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Network neighborhood for query Sequence : TNF13_HUMAN

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TNF13_HUMAN
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNF13_HUMAN
θ value	9.58617e-127 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

TNF13_MOUSE
θ value	7.14227e-106 (rank : 2)	NC score	0.992774 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D777, Q9ERP1	Gene names	Tnfsf13, April
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (CD256 antigen).

TN13B_HUMAN
θ value	4.29542e-18 (rank : 3)	NC score	0.724503 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y275	Gene names	TNFSF13B, BAFF, BLYS, TALL1, ZTNF4
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13B (TNF- and APOL- related leukocyte expressed ligand 1) (TALL-1) (B lymphocyte stimulator) (BLyS) (B cell-activating factor) (BAFF) (Dendritic cell- derived TNF-like molecule) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form].

TN13B_MOUSE
θ value	1.52774e-15 (rank : 4)	NC score	0.697911 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU72	Gene names	Tnfsf13b, Baff
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13B (B cell-activating factor) (BAFF) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form].

EDA_HUMAN
θ value	2.44474e-05 (rank : 5)	NC score	0.262357 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	2.44474e-05 (rank : 6)	NC score	0.260915 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

TNFA_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.154571 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P01375, O43647, Q9P1Q2, Q9UIV3	Gene names	TNF, TNFA, TNFSF2
Domain Architecture
Description	Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form].

SPT6H_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.085956 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

SPT6H_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.078262 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

TNF10_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.053840 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P50592	Gene names	Tnfsf10, Trail
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD253 antigen).

ATS18_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.007642 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

TNFA_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.110063 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P06804, O35853, Q62326, Q91VF3	Gene names	Tnf, Tnfa, Tnfsf2
Domain Architecture
Description	Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form].

TNFB_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.062853 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	P01374, Q8N4C3, Q9UKS8	Gene names	LTA, TNFB, TNFSF1
Domain Architecture
Description	Lymphotoxin-alpha precursor (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1).

BRCA1_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.012865 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

UBP53_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.015768 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

FREM1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.007977 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

RPGR_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.010878 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

TNF10_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.051754 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	P50591	Gene names	TNFSF10, APO2L, TRAIL
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD253 antigen).

TNF14_MOUSE
θ value	θ > 10 (rank : 19)	NC score	0.060772 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYH9	Gene names	Tnfsf14, Light
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 14 (CD258 antigen) [Contains: Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form].

Hits sorted by NC score

TNF13_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.58617e-127 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

TNF13_MOUSE
NC score	0.992774 (rank : 2)	θ value	7.14227e-106 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D777, Q9ERP1	Gene names	Tnfsf13, April
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (CD256 antigen).

TN13B_HUMAN
NC score	0.724503 (rank : 3)	θ value	4.29542e-18 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y275	Gene names	TNFSF13B, BAFF, BLYS, TALL1, ZTNF4
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13B (TNF- and APOL- related leukocyte expressed ligand 1) (TALL-1) (B lymphocyte stimulator) (BLyS) (B cell-activating factor) (BAFF) (Dendritic cell- derived TNF-like molecule) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form].

TN13B_MOUSE
NC score	0.697911 (rank : 4)	θ value	1.52774e-15 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU72	Gene names	Tnfsf13b, Baff
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13B (B cell-activating factor) (BAFF) (CD257 antigen) [Contains: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form].

EDA_HUMAN
NC score	0.262357 (rank : 5)	θ value	2.44474e-05 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
NC score	0.260915 (rank : 6)	θ value	2.44474e-05 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

TNFA_HUMAN
NC score	0.154571 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P01375, O43647, Q9P1Q2, Q9UIV3	Gene names	TNF, TNFA, TNFSF2
Domain Architecture
Description	Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form].

TNFA_MOUSE
NC score	0.110063 (rank : 8)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P06804, O35853, Q62326, Q91VF3	Gene names	Tnf, Tnfa, Tnfsf2
Domain Architecture
Description	Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form].

SPT6H_MOUSE
NC score	0.085956 (rank : 9)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

SPT6H_HUMAN
NC score	0.078262 (rank : 10)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

TNFB_HUMAN
NC score	0.062853 (rank : 11)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	P01374, Q8N4C3, Q9UKS8	Gene names	LTA, TNFB, TNFSF1
Domain Architecture
Description	Lymphotoxin-alpha precursor (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1).

TNF14_MOUSE
NC score	0.060772 (rank : 12)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYH9	Gene names	Tnfsf14, Light
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 14 (CD258 antigen) [Contains: Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form].

TNF10_MOUSE
NC score	0.053840 (rank : 13)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	P50592	Gene names	Tnfsf10, Trail
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD253 antigen).

TNF10_HUMAN
NC score	0.051754 (rank : 14)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	P50591	Gene names	TNFSF10, APO2L, TRAIL
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD253 antigen).

UBP53_HUMAN
NC score	0.015768 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

BRCA1_HUMAN
NC score	0.012865 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RPGR_HUMAN
NC score	0.010878 (rank : 17)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

FREM1_HUMAN
NC score	0.007977 (rank : 18)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

ATS18_MOUSE
NC score	0.007642 (rank : 19)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).