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Network neighborhood for query Sequence : NPAS2_MOUSE

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NPAS2_MOUSE
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CLOCK_HUMAN
θ value	0 (rank : 1)	NC score	0.970057 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	127	Shared Neighborhood Hits	66
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	0 (rank : 2)	NC score	0.967751 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

NPAS2_HUMAN
θ value	0 (rank : 3)	NC score	0.988447 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

BMAL1_HUMAN
θ value	3.4976e-36 (rank : 5)	NC score	0.844334 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	61
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	5.0505e-35 (rank : 6)	NC score	0.840459 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

EPAS1_HUMAN
θ value	2.59387e-31 (rank : 7)	NC score	0.799120 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

ARNT_HUMAN
θ value	1.28732e-30 (rank : 8)	NC score	0.806646 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	2.19584e-30 (rank : 9)	NC score	0.794218 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	213	Shared Neighborhood Hits	67
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

EPAS1_MOUSE
θ value	2.86786e-30 (rank : 10)	NC score	0.796372 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HIF1A_HUMAN
θ value	7.06379e-29 (rank : 11)	NC score	0.789520 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
θ value	1.12775e-26 (rank : 12)	NC score	0.788253 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

ARNT2_HUMAN
θ value	3.62785e-25 (rank : 13)	NC score	0.792269 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	3.62785e-25 (rank : 14)	NC score	0.792977 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SIM1_HUMAN
θ value	2.27762e-19 (rank : 15)	NC score	0.739487 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	2.27762e-19 (rank : 16)	NC score	0.739351 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
θ value	2.27762e-19 (rank : 17)	NC score	0.735514 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
θ value	1.92812e-18 (rank : 18)	NC score	0.734706 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

AHR_HUMAN
θ value	4.74913e-17 (rank : 19)	NC score	0.728155 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
θ value	6.85773e-16 (rank : 20)	NC score	0.719342 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NCOA1_MOUSE
θ value	6.85773e-16 (rank : 21)	NC score	0.632798 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	196	Shared Neighborhood Hits	55
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
θ value	1.52774e-15 (rank : 22)	NC score	0.627691 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
θ value	2.88119e-14 (rank : 23)	NC score	0.574757 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NPAS3_MOUSE
θ value	2.88119e-14 (rank : 24)	NC score	0.694680 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
θ value	1.86753e-13 (rank : 25)	NC score	0.690279 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NCOA2_MOUSE
θ value	3.18553e-13 (rank : 26)	NC score	0.572526 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_HUMAN
θ value	2.13673e-09 (rank : 27)	NC score	0.572833 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NPAS1_HUMAN
θ value	2.79066e-09 (rank : 28)	NC score	0.670979 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

PER3_MOUSE
θ value	2.79066e-09 (rank : 29)	NC score	0.449966 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

NPAS1_MOUSE
θ value	3.64472e-09 (rank : 30)	NC score	0.673607 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

PER3_HUMAN
θ value	6.21693e-09 (rank : 31)	NC score	0.415191 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	479	Shared Neighborhood Hits	46
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
θ value	8.11959e-09 (rank : 32)	NC score	0.405560 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER2_HUMAN
θ value	1.80886e-08 (rank : 33)	NC score	0.428411 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
θ value	1.17247e-07 (rank : 34)	NC score	0.423274 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	215	Shared Neighborhood Hits	39
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	1.17247e-07 (rank : 35)	NC score	0.417672 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

NCOA3_MOUSE
θ value	1.53129e-07 (rank : 36)	NC score	0.534608 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	203	Shared Neighborhood Hits	40
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NPAS4_HUMAN
θ value	4.45536e-07 (rank : 37)	NC score	0.523407 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	7.1131e-05 (rank : 38)	NC score	0.506795 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

EMSY_HUMAN
θ value	0.000786445 (rank : 39)	NC score	0.106111 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	296	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

SON_HUMAN
θ value	0.00390308 (rank : 40)	NC score	0.063305 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	1568	Shared Neighborhood Hits	55
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

EMSY_MOUSE
θ value	0.00509761 (rank : 41)	NC score	0.102766 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	294	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

CSPG2_MOUSE
θ value	0.0113563 (rank : 42)	NC score	0.020779 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	711	Shared Neighborhood Hits	22
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

BSN_MOUSE
θ value	0.0148317 (rank : 43)	NC score	0.047096 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	2057	Shared Neighborhood Hits	58
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GP112_HUMAN
θ value	0.0431538 (rank : 44)	NC score	0.026228 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

MLL3_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.044168 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYH9_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.025776 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.025373 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	1829	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GLI2_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.003061 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	971	Shared Neighborhood Hits	18
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MAML3_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.075763 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SON_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.051990 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	957	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TFE3_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.176752 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

HES7_HUMAN
θ value	0.279714 (rank : 52)	NC score	0.096850 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MITF_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.170312 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.279714 (rank : 54)	NC score	0.171355 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NCOA6_MOUSE
θ value	0.279714 (rank : 55)	NC score	0.082389 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	1076	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BHLH2_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.111490 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	0.365318 (rank : 57)	NC score	0.110622 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

HES7_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.092848 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MLL3_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.048374 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLX_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.159474 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.159039 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

USF1_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.142898 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.47712 (rank : 63)	NC score	0.142882 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

NCOA6_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.073872 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	1202	Shared Neighborhood Hits	53
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TULP4_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.027272 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MAML2_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.052058 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

SELPL_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.032057 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

USF2_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.134909 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	155	Shared Neighborhood Hits	30
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

ATX7_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.022761 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

MYH10_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.020172 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ZIMP7_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.035947 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	566	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CCAR1_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.018769 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CEP35_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.018712 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	811	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

MYH10_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.020011 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	1612	Shared Neighborhood Hits	25
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

USF2_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.127617 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

BHLH3_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.110704 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.108355 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

EPC1_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.013924 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MAML1_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.040924 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MYO15_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.021958 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CIKS_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.025726 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

MYH11_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.019352 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	1806	Shared Neighborhood Hits	28
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.019534 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	1777	Shared Neighborhood Hits	26
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NOTC1_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.001367 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NUAK1_MOUSE
θ value	2.36792 (rank : 85)	NC score	-0.003826 (rank : 144)
Query Neighborhood Hits	132	Target Neighborhood Hits	881	Shared Neighborhood Hits	6
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

OSBP2_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.010216 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	150	Shared Neighborhood Hits	7
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

SPTN5_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.008536 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

BAT3_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.026706 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CBP_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.028090 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	1051	Shared Neighborhood Hits	43
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PAX3_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.003564 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

RRBP1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.008541 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	1650	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SRBP2_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.083563 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TFEB_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.150652 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.151286 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

NACAM_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.032347 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RFX1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.022352 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

ZN746_HUMAN
θ value	4.03905 (rank : 97)	NC score	-0.003229 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

FA47A_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.014751 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

K1219_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.014433 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

MAGE1_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.023394 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	1389	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MED12_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.019810 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	262	Shared Neighborhood Hits	15
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

PI5PA_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.021221 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SCML1_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.012269 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UN30	Gene names	SCML1
Domain Architecture
Description	Sex comb on midleg-like protein 1.

TCFL5_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.127927 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

CEP63_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.010320 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	1005	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

EP400_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.020858 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

HES5_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.106550 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HEY1_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.128451 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.133608 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

KAD7_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.008944 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H2, Q8BVH3	Gene names	Ak7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

KAISO_MOUSE
θ value	6.88961 (rank : 111)	NC score	-0.002486 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	821	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

KIF4A_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.003742 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	1033	Shared Neighborhood Hits	21
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MAST4_HUMAN
θ value	6.88961 (rank : 113)	NC score	-0.001144 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	1804	Shared Neighborhood Hits	34
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MCM6_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.007552 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97311, Q80YQ7	Gene names	Mcm6, Mcmd6, Mis5
Domain Architecture
Description	DNA replication licensing factor MCM6 (Mis5 homolog).

MYCL1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.077527 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	146	Shared Neighborhood Hits	28
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.081913 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

PCLO_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.029895 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	2275	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TAF6_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.016189 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

TPR_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.008985 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	1921	Shared Neighborhood Hits	35
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

BARH2_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.000371 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

CU058_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.022782 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

DACH1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.020026 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

IRAK2_HUMAN
θ value	8.99809 (rank : 123)	NC score	-0.001279 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	714	Shared Neighborhood Hits	6
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

K1219_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.013046 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KCND3_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.001202 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

PCLO_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.025846 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	2046	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RHG09_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.003901 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SNPC4_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.012481 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SOX13_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.007505 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	495	Shared Neighborhood Hits	20
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

STK10_MOUSE
θ value	8.99809 (rank : 130)	NC score	-0.000182 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	2132	Shared Neighborhood Hits	37
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SYNPO_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.014370 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TEKT2_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.012288 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

BSN_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.050928 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	1537	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

HES3_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.070720 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES4_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.055333 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HEY2_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.132485 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.129758 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MAD4_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.053426 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAX_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.072135 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.083715 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MUC7_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.059939 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCQAP_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.053667 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	39
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SRBP1_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.103715 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.091758 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

Hits sorted by NC score

NPAS2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.988447 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

CLOCK_HUMAN
NC score	0.970057 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	127	Shared Neighborhood Hits	66
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.967751 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

BMAL1_HUMAN
NC score	0.844334 (rank : 5)	θ value	3.4976e-36 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	61
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.840459 (rank : 6)	θ value	5.0505e-35 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ARNT_HUMAN
NC score	0.806646 (rank : 7)	θ value	1.28732e-30 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

EPAS1_HUMAN
NC score	0.799120 (rank : 8)	θ value	2.59387e-31 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.796372 (rank : 9)	θ value	2.86786e-30 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

ARNT_MOUSE
NC score	0.794218 (rank : 10)	θ value	2.19584e-30 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	213	Shared Neighborhood Hits	67
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT2_MOUSE
NC score	0.792977 (rank : 11)	θ value	3.62785e-25 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.792269 (rank : 12)	θ value	3.62785e-25 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

HIF1A_HUMAN
NC score	0.789520 (rank : 13)	θ value	7.06379e-29 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.788253 (rank : 14)	θ value	1.12775e-26 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SIM1_HUMAN
NC score	0.739487 (rank : 15)	θ value	2.27762e-19 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.739351 (rank : 16)	θ value	2.27762e-19 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
NC score	0.735514 (rank : 17)	θ value	2.27762e-19 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
NC score	0.734706 (rank : 18)	θ value	1.92812e-18 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

AHR_HUMAN
NC score	0.728155 (rank : 19)	θ value	4.74913e-17 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.719342 (rank : 20)	θ value	6.85773e-16 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS3_MOUSE
NC score	0.694680 (rank : 21)	θ value	2.88119e-14 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
NC score	0.690279 (rank : 22)	θ value	1.86753e-13 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_MOUSE
NC score	0.673607 (rank : 23)	θ value	3.64472e-09 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.670979 (rank : 24)	θ value	2.79066e-09 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NCOA1_MOUSE
NC score	0.632798 (rank : 25)	θ value	6.85773e-16 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	196	Shared Neighborhood Hits	55
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.627691 (rank : 26)	θ value	1.52774e-15 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
NC score	0.574757 (rank : 27)	θ value	2.88119e-14 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
NC score	0.572833 (rank : 28)	θ value	2.13673e-09 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_MOUSE
NC score	0.572526 (rank : 29)	θ value	3.18553e-13 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_MOUSE
NC score	0.534608 (rank : 30)	θ value	1.53129e-07 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	203	Shared Neighborhood Hits	40
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NPAS4_HUMAN
NC score	0.523407 (rank : 31)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.506795 (rank : 32)	θ value	7.1131e-05 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PER3_MOUSE
NC score	0.449966 (rank : 33)	θ value	2.79066e-09 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_HUMAN
NC score	0.428411 (rank : 34)	θ value	1.80886e-08 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
NC score	0.423274 (rank : 35)	θ value	1.17247e-07 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	215	Shared Neighborhood Hits	39
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.417672 (rank : 36)	θ value	1.17247e-07 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
NC score	0.415191 (rank : 37)	θ value	6.21693e-09 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	479	Shared Neighborhood Hits	46
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.405560 (rank : 38)	θ value	8.11959e-09 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

TFE3_HUMAN
NC score	0.176752 (rank : 39)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_MOUSE
NC score	0.171355 (rank : 40)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_HUMAN
NC score	0.170312 (rank : 41)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
NC score	0.159474 (rank : 42)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.159039 (rank : 43)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TFEB_MOUSE
NC score	0.151286 (rank : 44)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.150652 (rank : 45)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
NC score	0.142898 (rank : 46)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.142882 (rank : 47)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.134909 (rank : 48)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	155	Shared Neighborhood Hits	30
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

HEY1_MOUSE
NC score	0.133608 (rank : 49)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
NC score	0.132485 (rank : 50)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.129758 (rank : 51)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_HUMAN
NC score	0.128451 (rank : 52)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TCFL5_HUMAN
NC score	0.127927 (rank : 53)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

USF2_MOUSE
NC score	0.127617 (rank : 54)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

BHLH2_HUMAN
NC score	0.111490 (rank : 55)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH3_HUMAN
NC score	0.110704 (rank : 56)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH2_MOUSE
NC score	0.110622 (rank : 57)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH3_MOUSE
NC score	0.108355 (rank : 58)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

HES5_MOUSE
NC score	0.106550 (rank : 59)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

EMSY_HUMAN
NC score	0.106111 (rank : 60)	θ value	0.000786445 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	296	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

SRBP1_HUMAN
NC score	0.103715 (rank : 61)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

EMSY_MOUSE
NC score	0.102766 (rank : 62)	θ value	0.00509761 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	294	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

HES7_HUMAN
NC score	0.096850 (rank : 63)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
NC score	0.092848 (rank : 64)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

SRBP1_MOUSE
NC score	0.091758 (rank : 65)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	132	Target Neighborhood Hits	384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAX_MOUSE
NC score	0.083715 (rank : 66)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

SRBP2_HUMAN
NC score	0.083563 (rank : 67)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

NCOA6_MOUSE
NC score	0.082389 (rank : 68)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	1076	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MYCL1_MOUSE
NC score	0.081913 (rank : 69)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_HUMAN
NC score	0.077527 (rank : 70)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	146	Shared Neighborhood Hits	28
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MAML3_HUMAN
NC score	0.075763 (rank : 71)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NCOA6_HUMAN
NC score	0.073872 (rank : 72)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	1202	Shared Neighborhood Hits	53
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MAX_HUMAN
NC score	0.072135 (rank : 73)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

HES3_MOUSE
NC score	0.070720 (rank : 74)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

SON_HUMAN
NC score	0.063305 (rank : 75)	θ value	0.00390308 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	1568	Shared Neighborhood Hits	55
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MUC7_HUMAN
NC score	0.059939 (rank : 76)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

HES4_HUMAN
NC score	0.055333 (rank : 77)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

PCQAP_HUMAN
NC score	0.053667 (rank : 78)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	39
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

MAD4_HUMAN
NC score	0.053426 (rank : 79)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAML2_HUMAN
NC score	0.052058 (rank : 80)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

SON_MOUSE
NC score	0.051990 (rank : 81)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	957	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BSN_HUMAN
NC score	0.050928 (rank : 82)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	1537	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MLL3_HUMAN
NC score	0.048374 (rank : 83)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BSN_MOUSE
NC score	0.047096 (rank : 84)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	2057	Shared Neighborhood Hits	58
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MLL3_MOUSE
NC score	0.044168 (rank : 85)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MAML1_MOUSE
NC score	0.040924 (rank : 86)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

ZIMP7_MOUSE
NC score	0.035947 (rank : 87)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	566	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

NACAM_MOUSE
NC score	0.032347 (rank : 88)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SELPL_MOUSE
NC score	0.032057 (rank : 89)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PCLO_MOUSE
NC score	0.029895 (rank : 90)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	2275	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CBP_MOUSE
NC score	0.028090 (rank : 91)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	1051	Shared Neighborhood Hits	43
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TULP4_HUMAN
NC score	0.027272 (rank : 92)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BAT3_HUMAN
NC score	0.026706 (rank : 93)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

GP112_HUMAN
NC score	0.026228 (rank : 94)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

PCLO_HUMAN
NC score	0.025846 (rank : 95)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	2046	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MYH9_HUMAN
NC score	0.025776 (rank : 96)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CIKS_HUMAN
NC score	0.025726 (rank : 97)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

MYH9_MOUSE
NC score	0.025373 (rank : 98)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	1829	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MAGE1_HUMAN
NC score	0.023394 (rank : 99)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	1389	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CU058_HUMAN
NC score	0.022782 (rank : 100)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P58505	Gene names	C21orf58
Domain Architecture	No domain graphic available
Description	Protein C21orf58.

ATX7_HUMAN
NC score	0.022761 (rank : 101)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

RFX1_HUMAN
NC score	0.022352 (rank : 102)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

MYO15_MOUSE
NC score	0.021958 (rank : 103)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PI5PA_HUMAN
NC score	0.021221 (rank : 104)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

EP400_HUMAN
NC score	0.020858 (rank : 105)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

CSPG2_MOUSE
NC score	0.020779 (rank : 106)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	711	Shared Neighborhood Hits	22
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MYH10_HUMAN
NC score	0.020172 (rank : 107)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

DACH1_HUMAN
NC score	0.020026 (rank : 108)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

MYH10_MOUSE
NC score	0.020011 (rank : 109)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	1612	Shared Neighborhood Hits	25
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MED12_HUMAN
NC score	0.019810 (rank : 110)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	262	Shared Neighborhood Hits	15
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MYH11_MOUSE
NC score	0.019534 (rank : 111)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	1777	Shared Neighborhood Hits	26
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.019352 (rank : 112)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	1806	Shared Neighborhood Hits	28
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CCAR1_MOUSE
NC score	0.018769 (rank : 113)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	414	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CEP35_HUMAN
NC score	0.018712 (rank : 114)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	811	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

TAF6_MOUSE
NC score	0.016189 (rank : 115)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

FA47A_HUMAN
NC score	0.014751 (rank : 116)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	451	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

K1219_HUMAN
NC score	0.014433 (rank : 117)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

SYNPO_MOUSE
NC score	0.014370 (rank : 118)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

EPC1_HUMAN
NC score	0.013924 (rank : 119)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

K1219_MOUSE
NC score	0.013046 (rank : 120)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

SNPC4_MOUSE
NC score	0.012481 (rank : 121)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

TEKT2_HUMAN
NC score	0.012288 (rank : 122)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

SCML1_HUMAN
NC score	0.012269 (rank : 123)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UN30	Gene names	SCML1
Domain Architecture
Description	Sex comb on midleg-like protein 1.

CEP63_HUMAN
NC score	0.010320 (rank : 124)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	1005	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

OSBP2_MOUSE
NC score	0.010216 (rank : 125)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	150	Shared Neighborhood Hits	7
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

TPR_HUMAN
NC score	0.008985 (rank : 126)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	1921	Shared Neighborhood Hits	35
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

KAD7_MOUSE
NC score	0.008944 (rank : 127)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H2, Q8BVH3	Gene names	Ak7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

RRBP1_MOUSE
NC score	0.008541 (rank : 128)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	1650	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SPTN5_HUMAN
NC score	0.008536 (rank : 129)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MCM6_MOUSE
NC score	0.007552 (rank : 130)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97311, Q80YQ7	Gene names	Mcm6, Mcmd6, Mis5
Domain Architecture
Description	DNA replication licensing factor MCM6 (Mis5 homolog).

SOX13_MOUSE
NC score	0.007505 (rank : 131)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	495	Shared Neighborhood Hits	20
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

RHG09_HUMAN
NC score	0.003901 (rank : 132)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

KIF4A_MOUSE
NC score	0.003742 (rank : 133)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	1033	Shared Neighborhood Hits	21
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

PAX3_HUMAN
NC score	0.003564 (rank : 134)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

GLI2_HUMAN
NC score	0.003061 (rank : 135)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	971	Shared Neighborhood Hits	18
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NOTC1_MOUSE
NC score	0.001367 (rank : 136)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	916	Shared Neighborhood Hits	11
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KCND3_HUMAN
NC score	0.001202 (rank : 137)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

BARH2_HUMAN
NC score	0.000371 (rank : 138)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

STK10_MOUSE
NC score	-0.000182 (rank : 139)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	2132	Shared Neighborhood Hits	37
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MAST4_HUMAN
NC score	-0.001144 (rank : 140)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	1804	Shared Neighborhood Hits	34
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IRAK2_HUMAN
NC score	-0.001279 (rank : 141)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	714	Shared Neighborhood Hits	6
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

KAISO_MOUSE
NC score	-0.002486 (rank : 142)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	821	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

ZN746_HUMAN
NC score	-0.003229 (rank : 143)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

NUAK1_MOUSE
NC score	-0.003826 (rank : 144)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	881	Shared Neighborhood Hits	6
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).