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Network neighborhood for query Sequence : HIF1A_HUMAN

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HIF1A_HUMAN
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HIF1A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
θ value	0 (rank : 2)	NC score	0.993764 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

EPAS1_HUMAN
θ value	3.1544e-162 (rank : 3)	NC score	0.976450 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
θ value	2.04462e-161 (rank : 4)	NC score	0.975288 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

SIM2_HUMAN
θ value	9.41505e-74 (rank : 5)	NC score	0.933296 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
θ value	3.57772e-73 (rank : 6)	NC score	0.932070 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM1_HUMAN
θ value	5.1662e-72 (rank : 7)	NC score	0.930358 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	5.1662e-72 (rank : 8)	NC score	0.929965 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

NPAS3_HUMAN
θ value	8.55514e-59 (rank : 9)	NC score	0.905775 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
θ value	8.55514e-59 (rank : 10)	NC score	0.905553 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_HUMAN
θ value	6.56568e-51 (rank : 11)	NC score	0.906437 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS1_MOUSE
θ value	1.04822e-48 (rank : 12)	NC score	0.906407 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

BMAL1_HUMAN
θ value	1.37539e-32 (rank : 13)	NC score	0.824301 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	1.37539e-32 (rank : 14)	NC score	0.822124 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	121	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_HUMAN
θ value	8.3442e-30 (rank : 15)	NC score	0.803915 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	3.17079e-29 (rank : 16)	NC score	0.800620 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

NPAS2_HUMAN
θ value	7.06379e-29 (rank : 17)	NC score	0.783999 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	7.06379e-29 (rank : 18)	NC score	0.789520 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

AHR_MOUSE
θ value	2.27234e-27 (rank : 19)	NC score	0.823816 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

ARNT_HUMAN
θ value	3.87602e-27 (rank : 20)	NC score	0.775330 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	5.06226e-27 (rank : 21)	NC score	0.762996 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

AHR_HUMAN
θ value	8.63488e-27 (rank : 22)	NC score	0.826852 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

ARNT2_HUMAN
θ value	4.28545e-26 (rank : 23)	NC score	0.780297 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	5.59698e-26 (rank : 24)	NC score	0.779499 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS4_HUMAN
θ value	2.35696e-16 (rank : 25)	NC score	0.675250 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	214	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	3.76295e-14 (rank : 26)	NC score	0.656738 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	245	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA2_MOUSE
θ value	1.42992e-13 (rank : 27)	NC score	0.566777 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	281	Shared Neighborhood Hits	44
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA1_HUMAN
θ value	3.18553e-13 (rank : 28)	NC score	0.622421 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	5.43371e-13 (rank : 29)	NC score	0.624412 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	42
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA2_HUMAN
θ value	9.26847e-13 (rank : 30)	NC score	0.566636 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	281	Shared Neighborhood Hits	46
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
θ value	1.47974e-10 (rank : 31)	NC score	0.565466 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	6.21693e-09 (rank : 32)	NC score	0.529163 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
θ value	6.43352e-06 (rank : 33)	NC score	0.338288 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER1_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.316526 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	215	Shared Neighborhood Hits	37
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	1.43324e-05 (rank : 35)	NC score	0.313510 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
θ value	0.000461057 (rank : 36)	NC score	0.303804 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_HUMAN
θ value	0.00228821 (rank : 37)	NC score	0.308402 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

SN1L2_HUMAN
θ value	0.00869519 (rank : 38)	NC score	0.003544 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

PER2_MOUSE
θ value	0.0113563 (rank : 39)	NC score	0.285404 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

MAGC1_HUMAN
θ value	0.0252991 (rank : 40)	NC score	0.040290 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

HCN1_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.014898 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

RGS3_MOUSE
θ value	0.163984 (rank : 42)	NC score	0.020047 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	1621	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ARHGF_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.019095 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

RIF1_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.022135 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	320	Shared Neighborhood Hits	10
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

MDC1_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.029222 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	1446	Shared Neighborhood Hits	50
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUC7_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.056982 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	538	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RUFY2_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.013438 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	1208	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

GPR64_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.009452 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

ASPP1_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.022139 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	1244	Shared Neighborhood Hits	41
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PHLB1_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.018226 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	1038	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

STON2_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.018980 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TARA_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.031600 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	1626	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LR37B_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.015031 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	392	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MEGF9_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.009977 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MYST4_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.009791 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

S12A7_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.007585 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

ANK2_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.009324 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

APBA2_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.008984 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	220	Shared Neighborhood Hits	5
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

GP156_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.016761 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

LIPS_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.016478 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

RUFY2_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.012204 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	820	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CJ047_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.017511 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

DDHD1_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.019565 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

NCOR2_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.014099 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	790	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PO6F2_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.014703 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

GSCR1_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.018285 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	674	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HES1_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.033216 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.033449 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

IRS2_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.014045 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SEPT9_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.009955 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	706	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SRRM2_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.039779 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	1296	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ASPP1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.013384 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	956	Shared Neighborhood Hits	28
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENPT_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.015770 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

CJ078_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.025507 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

EEA1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.000424 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	1796	Shared Neighborhood Hits	19
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGB1_HUMAN
θ value	4.03905 (rank : 76)	NC score	-0.000653 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	2297	Shared Neighborhood Hits	22
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HYES_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.012019 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

LRRC4_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.000813 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

PALM_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.012160 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PHF13_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.012909 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PO6F2_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.013438 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SRRM1_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.018454 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	966	Shared Neighborhood Hits	34
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TARSH_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.027499 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	768	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCRG1_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.007456 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

ATS1_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.001135 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

DOK4_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.010237 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.010259 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

IF16_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.009115 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

MUC2_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.019184 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PACS1_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.011837 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PASK_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.002822 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	867	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

PRG4_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.023960 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SN1L2_MOUSE
θ value	5.27518 (rank : 93)	NC score	-0.000594 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	944	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

TRI47_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.005670 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

ZN410_HUMAN
θ value	5.27518 (rank : 95)	NC score	-0.003887 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	716	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VK4, O00153, Q9BQ19	Gene names	ZNF410, APA1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 410 (Zinc finger protein APA-1) (Another partner for ARF 1).

AP2A1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.004387 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

BCL7B_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.008766 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q921K9, O89022, Q3TV31, Q3U2W0	Gene names	Bcl7b
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member B.

CBP_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.018302 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	1051	Shared Neighborhood Hits	35
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CF152_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.003682 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	704	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CMTA1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.008765 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

DTNA_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.004394 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

IFIH1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.004727 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LRRC7_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.000233 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	423	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MY18B_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.001481 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	1299	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYSM1_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.008220 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

ROBO1_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.000349 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	9
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SNPC2_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.010620 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

SRRM1_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.016777 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	690	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

FOXF2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.000805 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

G3BP2_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.003325 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

PDIP3_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.008763 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG81, Q6PE83, Q80X99, Q8CI28	Gene names	Poldip3
Domain Architecture	No domain graphic available
Description	Polymerase delta-interacting protein 3.

PLCB1_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.002718 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	531	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PP1RA_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.006405 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

PP4R1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.005868 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

ROBO1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.000101 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SRRM2_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.031561 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TACC2_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.005083 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	774	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ZN358_HUMAN
θ value	8.99809 (rank : 118)	NC score	-0.004702 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	840	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

HES5_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.064582 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HEY1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.083500 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	82	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.087321 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.093977 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.091866 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MITF_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.073595 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.075304 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.065863 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.065831 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TCFL5_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.075848 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.075204 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.070036 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	111	Shared Neighborhood Hits	15
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.069185 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.068423 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.068392 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.065699 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.061024 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

Hits sorted by NC score

HIF1A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.993764 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

EPAS1_HUMAN
NC score	0.976450 (rank : 3)	θ value	3.1544e-162 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.975288 (rank : 4)	θ value	2.04462e-161 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

SIM2_HUMAN
NC score	0.933296 (rank : 5)	θ value	9.41505e-74 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
NC score	0.932070 (rank : 6)	θ value	3.57772e-73 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM1_HUMAN
NC score	0.930358 (rank : 7)	θ value	5.1662e-72 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.929965 (rank : 8)	θ value	5.1662e-72 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

NPAS1_HUMAN
NC score	0.906437 (rank : 9)	θ value	6.56568e-51 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS1_MOUSE
NC score	0.906407 (rank : 10)	θ value	1.04822e-48 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS3_HUMAN
NC score	0.905775 (rank : 11)	θ value	8.55514e-59 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
NC score	0.905553 (rank : 12)	θ value	8.55514e-59 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

AHR_HUMAN
NC score	0.826852 (rank : 13)	θ value	8.63488e-27 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_HUMAN
NC score	0.824301 (rank : 14)	θ value	1.37539e-32 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

AHR_MOUSE
NC score	0.823816 (rank : 15)	θ value	2.27234e-27 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_MOUSE
NC score	0.822124 (rank : 16)	θ value	1.37539e-32 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	121	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_HUMAN
NC score	0.803915 (rank : 17)	θ value	8.3442e-30 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.800620 (rank : 18)	θ value	3.17079e-29 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

NPAS2_MOUSE
NC score	0.789520 (rank : 19)	θ value	7.06379e-29 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.783999 (rank : 20)	θ value	7.06379e-29 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ARNT2_HUMAN
NC score	0.780297 (rank : 21)	θ value	4.28545e-26 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.779499 (rank : 22)	θ value	5.59698e-26 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
NC score	0.775330 (rank : 23)	θ value	3.87602e-27 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.762996 (rank : 24)	θ value	5.06226e-27 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_HUMAN
NC score	0.675250 (rank : 25)	θ value	2.35696e-16 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	214	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.656738 (rank : 26)	θ value	3.76295e-14 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	245	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA1_MOUSE
NC score	0.624412 (rank : 27)	θ value	5.43371e-13 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	42
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.622421 (rank : 28)	θ value	3.18553e-13 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_MOUSE
NC score	0.566777 (rank : 29)	θ value	1.42992e-13 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	281	Shared Neighborhood Hits	44
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
NC score	0.566636 (rank : 30)	θ value	9.26847e-13 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	281	Shared Neighborhood Hits	46
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
NC score	0.565466 (rank : 31)	θ value	1.47974e-10 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
NC score	0.529163 (rank : 32)	θ value	6.21693e-09 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
NC score	0.338288 (rank : 33)	θ value	6.43352e-06 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER1_HUMAN
NC score	0.316526 (rank : 34)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	215	Shared Neighborhood Hits	37
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.313510 (rank : 35)	θ value	1.43324e-05 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
NC score	0.308402 (rank : 36)	θ value	0.00228821 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER3_HUMAN
NC score	0.303804 (rank : 37)	θ value	0.000461057 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.285404 (rank : 38)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

HEY2_HUMAN
NC score	0.093977 (rank : 39)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.091866 (rank : 40)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.087321 (rank : 41)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.083500 (rank : 42)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	82	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TCFL5_HUMAN
NC score	0.075848 (rank : 43)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MITF_MOUSE
NC score	0.075304 (rank : 44)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFE3_HUMAN
NC score	0.075204 (rank : 45)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
NC score	0.073595 (rank : 46)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFEB_HUMAN
NC score	0.070036 (rank : 47)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	111	Shared Neighborhood Hits	15
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.069185 (rank : 48)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
NC score	0.068423 (rank : 49)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.068392 (rank : 50)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MLX_HUMAN
NC score	0.065863 (rank : 51)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.065831 (rank : 52)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

USF2_HUMAN
NC score	0.065699 (rank : 53)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

HES5_MOUSE
NC score	0.064582 (rank : 54)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

USF2_MOUSE
NC score	0.061024 (rank : 55)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MUC7_HUMAN
NC score	0.056982 (rank : 56)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	538	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MAGC1_HUMAN
NC score	0.040290 (rank : 57)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SRRM2_HUMAN
NC score	0.039779 (rank : 58)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	1296	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

HES1_MOUSE
NC score	0.033449 (rank : 59)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.033216 (rank : 60)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

TARA_HUMAN
NC score	0.031600 (rank : 61)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	1626	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_MOUSE
NC score	0.031561 (rank : 62)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MDC1_HUMAN
NC score	0.029222 (rank : 63)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	1446	Shared Neighborhood Hits	50
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TARSH_HUMAN
NC score	0.027499 (rank : 64)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	768	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CJ078_MOUSE
NC score	0.025507 (rank : 65)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

PRG4_MOUSE
NC score	0.023960 (rank : 66)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ASPP1_MOUSE
NC score	0.022139 (rank : 67)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	1244	Shared Neighborhood Hits	41
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RIF1_HUMAN
NC score	0.022135 (rank : 68)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	320	Shared Neighborhood Hits	10
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

RGS3_MOUSE
NC score	0.020047 (rank : 69)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	1621	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DDHD1_HUMAN
NC score	0.019565 (rank : 70)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

MUC2_HUMAN
NC score	0.019184 (rank : 71)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ARHGF_HUMAN
NC score	0.019095 (rank : 72)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

STON2_HUMAN
NC score	0.018980 (rank : 73)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SRRM1_MOUSE
NC score	0.018454 (rank : 74)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	966	Shared Neighborhood Hits	34
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CBP_MOUSE
NC score	0.018302 (rank : 75)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	1051	Shared Neighborhood Hits	35
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GSCR1_HUMAN
NC score	0.018285 (rank : 76)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	674	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PHLB1_HUMAN
NC score	0.018226 (rank : 77)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	1038	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CJ047_MOUSE
NC score	0.017511 (rank : 78)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

SRRM1_HUMAN
NC score	0.016777 (rank : 79)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	690	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

GP156_MOUSE
NC score	0.016761 (rank : 80)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

LIPS_MOUSE
NC score	0.016478 (rank : 81)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

CENPT_MOUSE
NC score	0.015770 (rank : 82)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

LR37B_HUMAN
NC score	0.015031 (rank : 83)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	392	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

HCN1_HUMAN
NC score	0.014898 (rank : 84)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

PO6F2_MOUSE
NC score	0.014703 (rank : 85)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

NCOR2_MOUSE
NC score	0.014099 (rank : 86)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	790	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

IRS2_HUMAN
NC score	0.014045 (rank : 87)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

RUFY2_HUMAN
NC score	0.013438 (rank : 88)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	1208	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

PO6F2_HUMAN
NC score	0.013438 (rank : 89)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

ASPP1_HUMAN
NC score	0.013384 (rank : 90)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	956	Shared Neighborhood Hits	28
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PHF13_HUMAN
NC score	0.012909 (rank : 91)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

RUFY2_MOUSE
NC score	0.012204 (rank : 92)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	820	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

PALM_MOUSE
NC score	0.012160 (rank : 93)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

HYES_MOUSE
NC score	0.012019 (rank : 94)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

PACS1_MOUSE
NC score	0.011837 (rank : 95)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SNPC2_HUMAN
NC score	0.010620 (rank : 96)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

DOK4_MOUSE
NC score	0.010259 (rank : 97)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_HUMAN
NC score	0.010237 (rank : 98)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

MEGF9_MOUSE
NC score	0.009977 (rank : 99)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SEPT9_HUMAN
NC score	0.009955 (rank : 100)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	706	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

MYST4_HUMAN
NC score	0.009791 (rank : 101)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

GPR64_MOUSE
NC score	0.009452 (rank : 102)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

ANK2_HUMAN
NC score	0.009324 (rank : 103)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

IF16_HUMAN
NC score	0.009115 (rank : 104)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

APBA2_HUMAN
NC score	0.008984 (rank : 105)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	220	Shared Neighborhood Hits	5
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

BCL7B_MOUSE
NC score	0.008766 (rank : 106)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q921K9, O89022, Q3TV31, Q3U2W0	Gene names	Bcl7b
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member B.

CMTA1_HUMAN
NC score	0.008765 (rank : 107)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

PDIP3_MOUSE
NC score	0.008763 (rank : 108)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG81, Q6PE83, Q80X99, Q8CI28	Gene names	Poldip3
Domain Architecture	No domain graphic available
Description	Polymerase delta-interacting protein 3.

MYSM1_HUMAN
NC score	0.008220 (rank : 109)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

S12A7_MOUSE
NC score	0.007585 (rank : 110)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

TCRG1_MOUSE
NC score	0.007456 (rank : 111)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	947	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

PP1RA_MOUSE
NC score	0.006405 (rank : 112)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

PP4R1_MOUSE
NC score	0.005868 (rank : 113)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

TRI47_MOUSE
NC score	0.005670 (rank : 114)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TACC2_MOUSE
NC score	0.005083 (rank : 115)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	774	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

IFIH1_MOUSE
NC score	0.004727 (rank : 116)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DTNA_MOUSE
NC score	0.004394 (rank : 117)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

AP2A1_HUMAN
NC score	0.004387 (rank : 118)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

CF152_HUMAN
NC score	0.003682 (rank : 119)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	704	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

SN1L2_HUMAN
NC score	0.003544 (rank : 120)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

G3BP2_MOUSE
NC score	0.003325 (rank : 121)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

PASK_MOUSE
NC score	0.002822 (rank : 122)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	867	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

PLCB1_MOUSE
NC score	0.002718 (rank : 123)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	531	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

MY18B_HUMAN
NC score	0.001481 (rank : 124)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	1299	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ATS1_MOUSE
NC score	0.001135 (rank : 125)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

LRRC4_HUMAN
NC score	0.000813 (rank : 126)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

FOXF2_HUMAN
NC score	0.000805 (rank : 127)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

EEA1_HUMAN
NC score	0.000424 (rank : 128)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	1796	Shared Neighborhood Hits	19
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ROBO1_MOUSE
NC score	0.000349 (rank : 129)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	9
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

LRRC7_HUMAN
NC score	0.000233 (rank : 130)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	423	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

ROBO1_HUMAN
NC score	0.000101 (rank : 131)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SN1L2_MOUSE
NC score	-0.000594 (rank : 132)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	944	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

GOGB1_HUMAN
NC score	-0.000653 (rank : 133)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	2297	Shared Neighborhood Hits	22
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ZN410_HUMAN
NC score	-0.003887 (rank : 134)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	716	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VK4, O00153, Q9BQ19	Gene names	ZNF410, APA1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 410 (Zinc finger protein APA-1) (Another partner for ARF 1).

ZN358_HUMAN
NC score	-0.004702 (rank : 135)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	840	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.