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Network neighborhood for query Sequence : HYES_MOUSE

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HYES_MOUSE
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HYES_HUMAN
θ value	0 (rank : 1)	NC score	0.991298 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P34913, Q16764, Q9HBJ1, Q9HBJ2	Gene names	EPHX2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

HYES_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

ABHD4_MOUSE
θ value	6.43352e-06 (rank : 3)	NC score	0.296124 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VD66	Gene names	Abhd4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD4_HUMAN
θ value	2.44474e-05 (rank : 4)	NC score	0.291771 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB40, Q9H9E0	Gene names	ABHD4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

HYEP_MOUSE
θ value	0.000461057 (rank : 5)	NC score	0.208858 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D379	Gene names	Ephx1
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

SERHL_HUMAN
θ value	0.00134147 (rank : 6)	NC score	0.252718 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4I8, Q5H973, Q9BR29, Q9BR30, Q9Y3I9	Gene names	SERHL
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-).

ABHD5_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.258744 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

SEHL2_HUMAN
θ value	0.00869519 (rank : 8)	NC score	0.249672 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQF3, Q5JZ95, Q9UH21	Gene names	SERHL2
Domain Architecture
Description	Serine hydrolase-like protein 2 (EC 3.1.-.-).

HYEP_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.187006 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P07099, Q5VTJ6, Q9NP75, Q9NPE7, Q9NQU6, Q9NQU7, Q9NQU8, Q9NQU9, Q9NQV0, Q9NQV1, Q9NQV2	Gene names	EPHX1, EPHX, EPOX
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

ABHD5_MOUSE
θ value	0.0252991 (rank : 10)	NC score	0.251572 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBL9, Q9CTY3	Gene names	Abhd5
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5 (Lipid droplet-binding protein CGI-58).

PPME1_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.164190 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

CN029_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.105109 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5M8, Q7Z5M6, Q7Z5M7, Q8N4D2	Gene names	C14orf29
Domain Architecture
Description	Protein C14orf29.

SERHL_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.216455 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB5, Q9DCZ8	Gene names	Serhl
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-) (SHL).

PPME1_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.108509 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

AB14B_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.138120 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IU4, Q86VK8, Q8N8W5	Gene names	ABHD14B, CIB
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

MET7B_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.059129 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

AB14B_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.112895 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCR7	Gene names	Abhd14b, Cib
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

ELMO1_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.026732 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92556, Q29R79, Q96PB0, Q9H0I1	Gene names	ELMO1, KIAA0281
Domain Architecture
Description	Engulfment and cell motility protein 1 (CED-12 homolog).

ELMO1_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.026748 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BPU7, Q8BSY9, Q8K2C5, Q91ZU3	Gene names	Elmo1
Domain Architecture
Description	Engulfment and cell motility protein 1 (CED-12 homolog).

KIT_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.007341 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	953	Shared Neighborhood Hits	4
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

HIF1A_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.012019 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

XTP3B_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.021831 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DZ1, O95901, Q6UWN7, Q9NUY7, Q9UQL4	Gene names	C2orf30, XTP3TPB
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein precursor.

CT135_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.025015 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

KIT_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.003819 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

BPHL_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.060072 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R164, Q8BVH2, Q8R589, Q9DCC6	Gene names	Bphl
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein).

Hits sorted by NC score

HYES_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

HYES_HUMAN
NC score	0.991298 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P34913, Q16764, Q9HBJ1, Q9HBJ2	Gene names	EPHX2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

ABHD4_MOUSE
NC score	0.296124 (rank : 3)	θ value	6.43352e-06 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VD66	Gene names	Abhd4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD4_HUMAN
NC score	0.291771 (rank : 4)	θ value	2.44474e-05 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB40, Q9H9E0	Gene names	ABHD4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD5_HUMAN
NC score	0.258744 (rank : 5)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

SERHL_HUMAN
NC score	0.252718 (rank : 6)	θ value	0.00134147 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4I8, Q5H973, Q9BR29, Q9BR30, Q9Y3I9	Gene names	SERHL
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-).

ABHD5_MOUSE
NC score	0.251572 (rank : 7)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBL9, Q9CTY3	Gene names	Abhd5
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5 (Lipid droplet-binding protein CGI-58).

SEHL2_HUMAN
NC score	0.249672 (rank : 8)	θ value	0.00869519 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQF3, Q5JZ95, Q9UH21	Gene names	SERHL2
Domain Architecture
Description	Serine hydrolase-like protein 2 (EC 3.1.-.-).

SERHL_MOUSE
NC score	0.216455 (rank : 9)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB5, Q9DCZ8	Gene names	Serhl
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-) (SHL).

HYEP_MOUSE
NC score	0.208858 (rank : 10)	θ value	0.000461057 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D379	Gene names	Ephx1
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

HYEP_HUMAN
NC score	0.187006 (rank : 11)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P07099, Q5VTJ6, Q9NP75, Q9NPE7, Q9NQU6, Q9NQU7, Q9NQU8, Q9NQU9, Q9NQV0, Q9NQV1, Q9NQV2	Gene names	EPHX1, EPHX, EPOX
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

PPME1_MOUSE
NC score	0.164190 (rank : 12)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

AB14B_HUMAN
NC score	0.138120 (rank : 13)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IU4, Q86VK8, Q8N8W5	Gene names	ABHD14B, CIB
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

AB14B_MOUSE
NC score	0.112895 (rank : 14)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCR7	Gene names	Abhd14b, Cib
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

PPME1_HUMAN
NC score	0.108509 (rank : 15)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

CN029_HUMAN
NC score	0.105109 (rank : 16)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5M8, Q7Z5M6, Q7Z5M7, Q8N4D2	Gene names	C14orf29
Domain Architecture
Description	Protein C14orf29.

BPHL_MOUSE
NC score	0.060072 (rank : 17)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R164, Q8BVH2, Q8R589, Q9DCC6	Gene names	Bphl
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein).

MET7B_MOUSE
NC score	0.059129 (rank : 18)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

ELMO1_MOUSE
NC score	0.026748 (rank : 19)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BPU7, Q8BSY9, Q8K2C5, Q91ZU3	Gene names	Elmo1
Domain Architecture
Description	Engulfment and cell motility protein 1 (CED-12 homolog).

ELMO1_HUMAN
NC score	0.026732 (rank : 20)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q92556, Q29R79, Q96PB0, Q9H0I1	Gene names	ELMO1, KIAA0281
Domain Architecture
Description	Engulfment and cell motility protein 1 (CED-12 homolog).

CT135_HUMAN
NC score	0.025015 (rank : 21)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

XTP3B_HUMAN
NC score	0.021831 (rank : 22)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DZ1, O95901, Q6UWN7, Q9NUY7, Q9UQL4	Gene names	C2orf30, XTP3TPB
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein precursor.

HIF1A_HUMAN
NC score	0.012019 (rank : 23)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

KIT_HUMAN
NC score	0.007341 (rank : 24)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	953	Shared Neighborhood Hits	4
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
NC score	0.003819 (rank : 25)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).