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Network neighborhood for query Sequence : HYES_HUMAN

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HYES_HUMAN
SwissProt Accessions	P34913, Q16764, Q9HBJ1, Q9HBJ2	Gene names	EPHX2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HYES_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P34913, Q16764, Q9HBJ1, Q9HBJ2	Gene names	EPHX2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

HYES_MOUSE
θ value	0 (rank : 2)	NC score	0.991298 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

SERHL_HUMAN
θ value	1.87187e-05 (rank : 3)	NC score	0.294267 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4I8, Q5H973, Q9BR29, Q9BR30, Q9Y3I9	Gene names	SERHL
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-).

SEHL2_HUMAN
θ value	0.000121331 (rank : 4)	NC score	0.292408 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQF3, Q5JZ95, Q9UH21	Gene names	SERHL2
Domain Architecture
Description	Serine hydrolase-like protein 2 (EC 3.1.-.-).

ABHD4_HUMAN
θ value	0.000158464 (rank : 5)	NC score	0.282745 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TB40, Q9H9E0	Gene names	ABHD4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD4_MOUSE
θ value	0.000270298 (rank : 6)	NC score	0.287293 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD66	Gene names	Abhd4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD5_HUMAN
θ value	0.00228821 (rank : 7)	NC score	0.257118 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

ABHD5_MOUSE
θ value	0.00665767 (rank : 8)	NC score	0.251731 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBL9, Q9CTY3	Gene names	Abhd5
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5 (Lipid droplet-binding protein CGI-58).

SERHL_MOUSE
θ value	0.0113563 (rank : 9)	NC score	0.252639 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB5, Q9DCZ8	Gene names	Serhl
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-) (SHL).

AB14B_HUMAN
θ value	0.0252991 (rank : 10)	NC score	0.167901 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IU4, Q86VK8, Q8N8W5	Gene names	ABHD14B, CIB
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

PPME1_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.131366 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

HYEP_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.175609 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D379	Gene names	Ephx1
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

BPHL_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.100523 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R164, Q8BVH2, Q8R589, Q9DCC6	Gene names	Bphl
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein).

HYEP_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.155057 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P07099, Q5VTJ6, Q9NP75, Q9NPE7, Q9NQU6, Q9NQU7, Q9NQU8, Q9NQU9, Q9NQV0, Q9NQV1, Q9NQV2	Gene names	EPHX1, EPHX, EPOX
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

AB14B_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.144552 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCR7	Gene names	Abhd14b, Cib
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

CN029_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.084813 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5M8, Q7Z5M6, Q7Z5M7, Q8N4D2	Gene names	C14orf29
Domain Architecture
Description	Protein C14orf29.

MET7B_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.059076 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

DYHC_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.021136 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	729	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

CT135_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.031830 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YU0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf135 homolog.

DYHC_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.020453 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

KIT_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.005396 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

CT135_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.034310 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

BPHL_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.060068 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

PPME1_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.073292 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

Hits sorted by NC score

HYES_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P34913, Q16764, Q9HBJ1, Q9HBJ2	Gene names	EPHX2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

HYES_MOUSE
NC score	0.991298 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P34914, Q8CGV0	Gene names	Ephx2, Eph2
Domain Architecture
Description	Epoxide hydrolase 2 (EC 3.3.2.10) (Soluble epoxide hydrolase) (SEH) (Epoxide hydratase) (Cytosolic epoxide hydrolase) (CEH).

SERHL_HUMAN
NC score	0.294267 (rank : 3)	θ value	1.87187e-05 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4I8, Q5H973, Q9BR29, Q9BR30, Q9Y3I9	Gene names	SERHL
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-).

SEHL2_HUMAN
NC score	0.292408 (rank : 4)	θ value	0.000121331 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQF3, Q5JZ95, Q9UH21	Gene names	SERHL2
Domain Architecture
Description	Serine hydrolase-like protein 2 (EC 3.1.-.-).

ABHD4_MOUSE
NC score	0.287293 (rank : 5)	θ value	0.000270298 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD66	Gene names	Abhd4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD4_HUMAN
NC score	0.282745 (rank : 6)	θ value	0.000158464 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TB40, Q9H9E0	Gene names	ABHD4
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Lyso-N- acylphosphatidylethanolamine lipase) (Alpha/beta-hydrolase 4).

ABHD5_HUMAN
NC score	0.257118 (rank : 7)	θ value	0.00228821 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WTS1, Q9Y369	Gene names	ABHD5, NCIE2
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5.

SERHL_MOUSE
NC score	0.252639 (rank : 8)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB5, Q9DCZ8	Gene names	Serhl
Domain Architecture
Description	Serine hydrolase-like protein (EC 3.1.-.-) (SHL).

ABHD5_MOUSE
NC score	0.251731 (rank : 9)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBL9, Q9CTY3	Gene names	Abhd5
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 5 (Lipid droplet-binding protein CGI-58).

HYEP_MOUSE
NC score	0.175609 (rank : 10)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D379	Gene names	Ephx1
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

AB14B_HUMAN
NC score	0.167901 (rank : 11)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IU4, Q86VK8, Q8N8W5	Gene names	ABHD14B, CIB
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

HYEP_HUMAN
NC score	0.155057 (rank : 12)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P07099, Q5VTJ6, Q9NP75, Q9NPE7, Q9NQU6, Q9NQU7, Q9NQU8, Q9NQU9, Q9NQV0, Q9NQV1, Q9NQV2	Gene names	EPHX1, EPHX, EPOX
Domain Architecture
Description	Epoxide hydrolase 1 (EC 3.3.2.9) (Microsomal epoxide hydrolase) (Epoxide hydratase).

AB14B_MOUSE
NC score	0.144552 (rank : 13)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCR7	Gene names	Abhd14b, Cib
Domain Architecture	No domain graphic available
Description	Abhydrolase domain-containing protein 14B (CCG1-interacting factor B).

PPME1_MOUSE
NC score	0.131366 (rank : 14)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

BPHL_MOUSE
NC score	0.100523 (rank : 15)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R164, Q8BVH2, Q8R589, Q9DCC6	Gene names	Bphl
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein).

CN029_HUMAN
NC score	0.084813 (rank : 16)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5M8, Q7Z5M6, Q7Z5M7, Q8N4D2	Gene names	C14orf29
Domain Architecture
Description	Protein C14orf29.

PPME1_HUMAN
NC score	0.073292 (rank : 17)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

BPHL_HUMAN
NC score	0.060068 (rank : 18)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

MET7B_MOUSE
NC score	0.059076 (rank : 19)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

CT135_HUMAN
NC score	0.034310 (rank : 20)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

CT135_MOUSE
NC score	0.031830 (rank : 21)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YU0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf135 homolog.

DYHC_MOUSE
NC score	0.021136 (rank : 22)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	729	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.020453 (rank : 23)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

KIT_HUMAN
NC score	0.005396 (rank : 24)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).