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Network neighborhood for query Sequence : HES3_MOUSE

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HES3_MOUSE
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HES3_MOUSE
θ value	1.18549e-84 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES5_MOUSE
θ value	8.97725e-08 (rank : 2)	NC score	0.749049 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HES1_HUMAN
θ value	1.17247e-07 (rank : 3)	NC score	0.687485 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	1.17247e-07 (rank : 4)	NC score	0.687323 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES4_HUMAN
θ value	1.17247e-07 (rank : 5)	NC score	0.714274 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES7_HUMAN
θ value	8.40245e-06 (rank : 6)	NC score	0.636604 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
θ value	8.40245e-06 (rank : 7)	NC score	0.634729 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES2_HUMAN
θ value	7.1131e-05 (rank : 8)	NC score	0.674816 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES2_MOUSE
θ value	0.000158464 (rank : 9)	NC score	0.676001 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HEY2_HUMAN
θ value	0.000602161 (rank : 10)	NC score	0.570131 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	0.00102713 (rank : 11)	NC score	0.568544 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

BHLH3_MOUSE
θ value	0.00228821 (rank : 12)	NC score	0.477905 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

HES6_MOUSE
θ value	0.00228821 (rank : 13)	NC score	0.572045 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

BHLH2_HUMAN
θ value	0.00298849 (rank : 14)	NC score	0.478036 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

HEY1_HUMAN
θ value	0.00298849 (rank : 15)	NC score	0.555748 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	0.00298849 (rank : 16)	NC score	0.558593 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

BHLH2_MOUSE
θ value	0.00390308 (rank : 17)	NC score	0.467223 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH3_HUMAN
θ value	0.00509761 (rank : 18)	NC score	0.475450 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

HES6_HUMAN
θ value	0.00509761 (rank : 19)	NC score	0.575043 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

OLIG2_HUMAN
θ value	0.125558 (rank : 20)	NC score	0.121758 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.121723 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

BMAL1_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.133008 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.134575 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

OLIG3_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.105780 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.104184 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

AHR_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.081527 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.080454 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

CLOCK_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.089257 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	127	Shared Neighborhood Hits	18
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.086471 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

LYL1_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.072799 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

ASCL2_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.071771 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ASCL2_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.068693 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

GNAS1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.010540 (rank : 66)
Query Neighborhood Hits	38	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TAL1_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.067980 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

MAD4_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.055790 (rank : 61)
Query Neighborhood Hits	38	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

TAL1_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.064523 (rank : 51)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

EI2BD_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.022345 (rank : 65)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

LYL1_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.066849 (rank : 46)
Query Neighborhood Hits	38	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

ARNT2_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.064946 (rank : 49)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.066273 (rank : 47)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.065116 (rank : 48)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.064924 (rank : 50)
Query Neighborhood Hits	38	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BHLH4_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.062154 (rank : 55)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.062813 (rank : 52)
Query Neighborhood Hits	38	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH8_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.053201 (rank : 63)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	14
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.054130 (rank : 62)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.050339 (rank : 64)
Query Neighborhood Hits	38	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.062715 (rank : 54)
Query Neighborhood Hits	38	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MITF_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.076704 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.074424 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.081453 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.081597 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

NPAS2_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.070983 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.070720 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

OLIG1_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.060842 (rank : 57)
Query Neighborhood Hits	38	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.058599 (rank : 59)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

SRBP1_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.067142 (rank : 45)
Query Neighborhood Hits	38	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.061978 (rank : 56)
Query Neighborhood Hits	38	Target Neighborhood Hits	384	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.071277 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TFE3_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.077970 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.057986 (rank : 60)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.058970 (rank : 58)
Query Neighborhood Hits	38	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.073600 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.073568 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.062808 (rank : 53)
Query Neighborhood Hits	38	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.067156 (rank : 44)
Query Neighborhood Hits	38	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

Hits sorted by NC score

HES3_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.18549e-84 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES5_MOUSE
NC score	0.749049 (rank : 2)	θ value	8.97725e-08 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HES4_HUMAN
NC score	0.714274 (rank : 3)	θ value	1.17247e-07 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES1_HUMAN
NC score	0.687485 (rank : 4)	θ value	1.17247e-07 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
NC score	0.687323 (rank : 5)	θ value	1.17247e-07 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES2_MOUSE
NC score	0.676001 (rank : 6)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES2_HUMAN
NC score	0.674816 (rank : 7)	θ value	7.1131e-05 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES7_HUMAN
NC score	0.636604 (rank : 8)	θ value	8.40245e-06 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
NC score	0.634729 (rank : 9)	θ value	8.40245e-06 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES6_HUMAN
NC score	0.575043 (rank : 10)	θ value	0.00509761 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

HES6_MOUSE
NC score	0.572045 (rank : 11)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

HEY2_HUMAN
NC score	0.570131 (rank : 12)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.568544 (rank : 13)	θ value	0.00102713 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.558593 (rank : 14)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.555748 (rank : 15)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

BHLH2_HUMAN
NC score	0.478036 (rank : 16)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH3_MOUSE
NC score	0.477905 (rank : 17)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH3_HUMAN
NC score	0.475450 (rank : 18)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH2_MOUSE
NC score	0.467223 (rank : 19)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BMAL1_MOUSE
NC score	0.134575 (rank : 20)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BMAL1_HUMAN
NC score	0.133008 (rank : 21)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

OLIG2_HUMAN
NC score	0.121758 (rank : 22)	θ value	0.125558 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
NC score	0.121723 (rank : 23)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
NC score	0.105780 (rank : 24)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
NC score	0.104184 (rank : 25)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

CLOCK_HUMAN
NC score	0.089257 (rank : 26)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	127	Shared Neighborhood Hits	18
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.086471 (rank : 27)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

MLX_MOUSE
NC score	0.081597 (rank : 28)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	38	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

AHR_HUMAN
NC score	0.081527 (rank : 29)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

MLX_HUMAN
NC score	0.081453 (rank : 30)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	38	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

AHR_MOUSE
NC score	0.080454 (rank : 31)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

TFE3_HUMAN
NC score	0.077970 (rank : 32)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	38	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
NC score	0.076704 (rank : 33)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	38	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.074424 (rank : 34)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	24
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF1_HUMAN
NC score	0.073600 (rank : 35)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.073568 (rank : 36)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	38	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

LYL1_MOUSE
NC score	0.072799 (rank : 37)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

ASCL2_HUMAN
NC score	0.071771 (rank : 38)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

SRBP2_HUMAN
NC score	0.071277 (rank : 39)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	38	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

NPAS2_HUMAN
NC score	0.070983 (rank : 40)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	38	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
NC score	0.070720 (rank : 41)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	38	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

ASCL2_MOUSE
NC score	0.068693 (rank : 42)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

TAL1_HUMAN
NC score	0.067980 (rank : 43)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

USF2_MOUSE
NC score	0.067156 (rank : 44)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	38	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

SRBP1_HUMAN
NC score	0.067142 (rank : 45)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	38	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

LYL1_HUMAN
NC score	0.066849 (rank : 46)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

ARNT2_MOUSE
NC score	0.066273 (rank : 47)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
NC score	0.065116 (rank : 48)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT2_HUMAN
NC score	0.064946 (rank : 49)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_MOUSE
NC score	0.064924 (rank : 50)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TAL1_MOUSE
NC score	0.064523 (rank : 51)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

BHLH4_MOUSE
NC score	0.062813 (rank : 52)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	38	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

USF2_HUMAN
NC score	0.062808 (rank : 53)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	38	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MAD1_MOUSE
NC score	0.062715 (rank : 54)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	38	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

BHLH4_HUMAN
NC score	0.062154 (rank : 55)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

SRBP1_MOUSE
NC score	0.061978 (rank : 56)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	38	Target Neighborhood Hits	384	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

OLIG1_HUMAN
NC score	0.060842 (rank : 57)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	38	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

TFEB_MOUSE
NC score	0.058970 (rank : 58)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	38	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

OLIG1_MOUSE
NC score	0.058599 (rank : 59)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

TFEB_HUMAN
NC score	0.057986 (rank : 60)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	38	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MAD4_HUMAN
NC score	0.055790 (rank : 61)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

BHLH8_MOUSE
NC score	0.054130 (rank : 62)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	38	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_HUMAN
NC score	0.053201 (rank : 63)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	14
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD1_HUMAN
NC score	0.050339 (rank : 64)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	38	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

EI2BD_HUMAN
NC score	0.022345 (rank : 65)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

GNAS1_HUMAN
NC score	0.010540 (rank : 66)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).