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Network neighborhood for query Sequence : EI2BD_HUMAN

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EI2BD_HUMAN
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EI2BD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

EI2BD_MOUSE
θ value	0 (rank : 2)	NC score	0.987486 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

EI2BA_MOUSE
θ value	5.79196e-23 (rank : 3)	NC score	0.729860 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LC8	Gene names	Eif2b1
Domain Architecture
Description	Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha).

EI2BA_HUMAN
θ value	2.87452e-22 (rank : 4)	NC score	0.725957 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q14232	Gene names	EIF2B1, EIF2BA
Domain Architecture
Description	Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha).

EI2BB_HUMAN
θ value	4.74913e-17 (rank : 5)	NC score	0.652683 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P49770, O43201	Gene names	EIF2B2, EIF2BB
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta) (S20I15) (S20III15).

EI2BB_MOUSE
θ value	6.20254e-17 (rank : 6)	NC score	0.649929 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LD9	Gene names	Eif2b2
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta).

ZC11A_MOUSE
θ value	0.0193708 (rank : 7)	NC score	0.072096 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZEP1_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.044219 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	1036	Shared Neighborhood Hits	9
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZEP1_MOUSE
θ value	0.21417 (rank : 9)	NC score	0.041599 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

OGFR_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.024386 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	1582	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ZN366_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.005343 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	732	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

ALO17_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.051090 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NACAM_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.024020 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	1866	Shared Neighborhood Hits	14
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CDC20_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.016818 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

SPEG_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.011658 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	1762	Shared Neighborhood Hits	12
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.012097 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	1959	Shared Neighborhood Hits	10
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UD14_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.016115 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P22310	Gene names	UGT1A4, GNT1, UGT1
Domain Architecture
Description	UDP-glucuronosyltransferase 1-4 precursor (EC 2.4.1.17) (UDP- glucuronosyltransferase 1A4) (UDPGT) (UGT1*4) (UGT1-04) (UGT1.4) (UGT- 1D) (UGT1D) (Bilirubin-specific UDPGT isozyme 2) (HUG-BR2).

PPE2_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.019062 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

ADDB_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.018918 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	574	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BSN_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.021929 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	1537	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

LIMA1_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.021214 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

OXRP_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.015261 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	544	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PHF3_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.028143 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

UTS2_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.045531 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZQ3	Gene names	Uts2, Ucn2
Domain Architecture	No domain graphic available
Description	Urotensin-2 precursor (Urotensin-II) (U-II) (UII).

DDX49_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.005717 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DIDO1_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.021099 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

M3K15_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.002758 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	914	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

HES3_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.022345 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

KCNN3_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.008894 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

NEMO_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.005233 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	820	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

SC11A_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.005520 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

UD13_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.012476 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P35503	Gene names	UGT1A3, GNT1, UGT1
Domain Architecture
Description	UDP-glucuronosyltransferase 1-3 precursor (EC 2.4.1.17) (UDP- glucuronosyltransferase 1A3) (UDPGT) (UGT1*3) (UGT1-03) (UGT1.3) (UGT- 1C) (UGT1C).

MAVS_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.017797 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

PLCE_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.013013 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUQ2, Q8IZ47, Q9BQG4	Gene names	AGPAT5
Domain Architecture
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase-epsilon) (LPAAT-epsilon) (1-acylglycerol-3-phosphate O-acyltransferase 5).

Hits sorted by NC score

EI2BD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UI10, Q5BJF4, Q9BUV9, Q9UBG4, Q9UIQ9, Q9UJ95	Gene names	EIF2B4, EIF2BD
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

EI2BD_MOUSE
NC score	0.987486 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

EI2BA_MOUSE
NC score	0.729860 (rank : 3)	θ value	5.79196e-23 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LC8	Gene names	Eif2b1
Domain Architecture
Description	Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha).

EI2BA_HUMAN
NC score	0.725957 (rank : 4)	θ value	2.87452e-22 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q14232	Gene names	EIF2B1, EIF2BA
Domain Architecture
Description	Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha).

EI2BB_HUMAN
NC score	0.652683 (rank : 5)	θ value	4.74913e-17 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P49770, O43201	Gene names	EIF2B2, EIF2BB
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta) (S20I15) (S20III15).

EI2BB_MOUSE
NC score	0.649929 (rank : 6)	θ value	6.20254e-17 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LD9	Gene names	Eif2b2
Domain Architecture
Description	Translation initiation factor eIF-2B subunit beta (eIF-2B GDP-GTP exchange factor subunit beta).

ZC11A_MOUSE
NC score	0.072096 (rank : 7)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ALO17_HUMAN
NC score	0.051090 (rank : 8)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

UTS2_MOUSE
NC score	0.045531 (rank : 9)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZQ3	Gene names	Uts2, Ucn2
Domain Architecture	No domain graphic available
Description	Urotensin-2 precursor (Urotensin-II) (U-II) (UII).

ZEP1_HUMAN
NC score	0.044219 (rank : 10)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	1036	Shared Neighborhood Hits	9
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZEP1_MOUSE
NC score	0.041599 (rank : 11)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PHF3_HUMAN
NC score	0.028143 (rank : 12)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

OGFR_HUMAN
NC score	0.024386 (rank : 13)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	1582	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NACAM_MOUSE
NC score	0.024020 (rank : 14)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	1866	Shared Neighborhood Hits	14
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HES3_MOUSE
NC score	0.022345 (rank : 15)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

BSN_HUMAN
NC score	0.021929 (rank : 16)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	1537	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

LIMA1_HUMAN
NC score	0.021214 (rank : 17)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

DIDO1_HUMAN
NC score	0.021099 (rank : 18)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PPE2_MOUSE
NC score	0.019062 (rank : 19)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

ADDB_MOUSE
NC score	0.018918 (rank : 20)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	574	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

MAVS_MOUSE
NC score	0.017797 (rank : 21)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

CDC20_HUMAN
NC score	0.016818 (rank : 22)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

UD14_HUMAN
NC score	0.016115 (rank : 23)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P22310	Gene names	UGT1A4, GNT1, UGT1
Domain Architecture
Description	UDP-glucuronosyltransferase 1-4 precursor (EC 2.4.1.17) (UDP- glucuronosyltransferase 1A4) (UDPGT) (UGT1*4) (UGT1-04) (UGT1.4) (UGT- 1D) (UGT1D) (Bilirubin-specific UDPGT isozyme 2) (HUG-BR2).

OXRP_HUMAN
NC score	0.015261 (rank : 24)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	544	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PLCE_HUMAN
NC score	0.013013 (rank : 25)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUQ2, Q8IZ47, Q9BQG4	Gene names	AGPAT5
Domain Architecture
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase-epsilon) (LPAAT-epsilon) (1-acylglycerol-3-phosphate O-acyltransferase 5).

UD13_HUMAN
NC score	0.012476 (rank : 26)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P35503	Gene names	UGT1A3, GNT1, UGT1
Domain Architecture
Description	UDP-glucuronosyltransferase 1-3 precursor (EC 2.4.1.17) (UDP- glucuronosyltransferase 1A3) (UDPGT) (UGT1*3) (UGT1-03) (UGT1.3) (UGT- 1C) (UGT1C).

SPEG_MOUSE
NC score	0.012097 (rank : 27)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	1959	Shared Neighborhood Hits	10
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_HUMAN
NC score	0.011658 (rank : 28)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	1762	Shared Neighborhood Hits	12
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

KCNN3_HUMAN
NC score	0.008894 (rank : 29)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

DDX49_HUMAN
NC score	0.005717 (rank : 30)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	223	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

SC11A_MOUSE
NC score	0.005520 (rank : 31)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

ZN366_HUMAN
NC score	0.005343 (rank : 32)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	732	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

NEMO_HUMAN
NC score	0.005233 (rank : 33)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	820	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

M3K15_HUMAN
NC score	0.002758 (rank : 34)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	914	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).