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Network neighborhood for query Sequence : CIKS_HUMAN

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CIKS_HUMAN
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CIKS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

RGS3_MOUSE
θ value	0.00298849 (rank : 2)	NC score	0.077284 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	1621	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PHC2_HUMAN
θ value	0.00665767 (rank : 3)	NC score	0.097016 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

ADA12_MOUSE
θ value	0.0113563 (rank : 4)	NC score	0.039409 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	474	Shared Neighborhood Hits	11
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CASL_HUMAN
θ value	0.0148317 (rank : 5)	NC score	0.111155 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

MLL4_HUMAN
θ value	0.0148317 (rank : 6)	NC score	0.089833 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	722	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ARS2_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.143152 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ARS2_MOUSE
θ value	0.0563607 (rank : 8)	NC score	0.141987 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CASL_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.096943 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

PAR3L_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.049587 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	297	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

LRBA_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.045888 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

WNK2_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.023791 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	1407	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

FOXB2_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.025868 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

PHLA1_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.095013 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

JHD2C_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.038503 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

SELPL_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.062395 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	588	Shared Neighborhood Hits	20
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MLL3_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.055596 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	1644	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AMELX_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.062000 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

PCLO_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.047345 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	2275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PHLA1_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.080697 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PLEC1_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.013084 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	1326	Shared Neighborhood Hits	8
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

TMC8_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.042591 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IU68, Q8IWU7, Q8N358, Q8NF04	Gene names	TMC8, EVER2, EVIN2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2).

AKAP2_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.037988 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MAST4_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.011069 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SYNM_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.040561 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

TMBI1_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.041951 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ3, Q8CH91, Q99KB6	Gene names	Tmbim1, Recs1
Domain Architecture
Description	Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein) (Responsive to centrifugal force and shear stress gene 1 protein).

KLF4_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.005794 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	694	Shared Neighborhood Hits	4
SwissProt Accessions	Q60793, P70421	Gene names	Klf4, Ezf, Gklf, Zie
Domain Architecture
Description	Krueppel-like factor 4 (Gut-enriched krueppel-like factor) (Epithelial zinc-finger protein EZF).

NPAS2_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.025726 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	132	Shared Neighborhood Hits	8
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

PO6F2_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.036765 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PTN23_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.032820 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	726	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RGS3_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.061348 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	27
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IF35_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.044302 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

K1024_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.035506 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

MILK1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.037101 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRBP1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.049400 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

4ET_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.036780 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CQ039_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.040366 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVV7, Q8TEB5, Q9BW50	Gene names	C17orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf39.

GP179_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.029115 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	372	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

NFAC1_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.030982 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SOX7_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.016499 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

TERF2_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.032116 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

DNER_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.008269 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	460	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

MAP1B_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.022415 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PCLO_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.045358 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	2046	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TNR6A_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.028542 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	343	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZN645_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.051732 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	265	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

KCNK4_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.017230 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

LEG3_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.019661 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

RC3H1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.021660 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RNF38_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.019184 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

SRBP2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.033999 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

BNC1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.013962 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	460	Shared Neighborhood Hits	5
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

CBPD_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.010243 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

GLIS3_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.002892 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

HXD10_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.006550 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	P28359, Q91WU9	Gene names	Hoxd10, Hox-4.5, Hoxd-10
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4.5) (Hox-5.3).

PO6F2_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.032351 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PTN23_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.027547 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	646	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TIF1G_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.014973 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZF106_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.016569 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ZN750_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.027646 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BCAR1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.062759 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	554	Shared Neighborhood Hits	18
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.061460 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	438	Shared Neighborhood Hits	15
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PHC2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.050700 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

Hits sorted by NC score

CIKS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

ARS2_HUMAN
NC score	0.143152 (rank : 2)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ARS2_MOUSE
NC score	0.141987 (rank : 3)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CASL_HUMAN
NC score	0.111155 (rank : 4)	θ value	0.0148317 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PHC2_HUMAN
NC score	0.097016 (rank : 5)	θ value	0.00665767 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

CASL_MOUSE
NC score	0.096943 (rank : 6)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

PHLA1_HUMAN
NC score	0.095013 (rank : 7)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

MLL4_HUMAN
NC score	0.089833 (rank : 8)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	722	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PHLA1_MOUSE
NC score	0.080697 (rank : 9)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

RGS3_MOUSE
NC score	0.077284 (rank : 10)	θ value	0.00298849 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	1621	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BCAR1_HUMAN
NC score	0.062759 (rank : 11)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	554	Shared Neighborhood Hits	18
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SELPL_MOUSE
NC score	0.062395 (rank : 12)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	588	Shared Neighborhood Hits	20
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

AMELX_HUMAN
NC score	0.062000 (rank : 13)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

BCAR1_MOUSE
NC score	0.061460 (rank : 14)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	438	Shared Neighborhood Hits	15
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

RGS3_HUMAN
NC score	0.061348 (rank : 15)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	27
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MLL3_HUMAN
NC score	0.055596 (rank : 16)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	1644	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ZN645_HUMAN
NC score	0.051732 (rank : 17)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	265	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

PHC2_MOUSE
NC score	0.050700 (rank : 18)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PAR3L_HUMAN
NC score	0.049587 (rank : 19)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	297	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

SRBP1_HUMAN
NC score	0.049400 (rank : 20)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PCLO_MOUSE
NC score	0.047345 (rank : 21)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	2275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LRBA_HUMAN
NC score	0.045888 (rank : 22)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

PCLO_HUMAN
NC score	0.045358 (rank : 23)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	2046	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

IF35_MOUSE
NC score	0.044302 (rank : 24)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

TMC8_HUMAN
NC score	0.042591 (rank : 25)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IU68, Q8IWU7, Q8N358, Q8NF04	Gene names	TMC8, EVER2, EVIN2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2).

TMBI1_MOUSE
NC score	0.041951 (rank : 26)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ3, Q8CH91, Q99KB6	Gene names	Tmbim1, Recs1
Domain Architecture
Description	Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein) (Responsive to centrifugal force and shear stress gene 1 protein).

SYNM_HUMAN
NC score	0.040561 (rank : 27)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96I59	Gene names	NARS2
Domain Architecture	No domain graphic available
Description	Probable asparaginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.22) (Asparagine--tRNA ligase) (AsnRS).

CQ039_HUMAN
NC score	0.040366 (rank : 28)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVV7, Q8TEB5, Q9BW50	Gene names	C17orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf39.

ADA12_MOUSE
NC score	0.039409 (rank : 29)	θ value	0.0113563 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	474	Shared Neighborhood Hits	11
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

JHD2C_HUMAN
NC score	0.038503 (rank : 30)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

AKAP2_HUMAN
NC score	0.037988 (rank : 31)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MILK1_HUMAN
NC score	0.037101 (rank : 32)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

4ET_HUMAN
NC score	0.036780 (rank : 33)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

PO6F2_MOUSE
NC score	0.036765 (rank : 34)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

K1024_HUMAN
NC score	0.035506 (rank : 35)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

SRBP2_HUMAN
NC score	0.033999 (rank : 36)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

PTN23_MOUSE
NC score	0.032820 (rank : 37)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	726	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PO6F2_HUMAN
NC score	0.032351 (rank : 38)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TERF2_HUMAN
NC score	0.032116 (rank : 39)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

NFAC1_HUMAN
NC score	0.030982 (rank : 40)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

GP179_HUMAN
NC score	0.029115 (rank : 41)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	372	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

TNR6A_HUMAN
NC score	0.028542 (rank : 42)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	343	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZN750_MOUSE
NC score	0.027646 (rank : 43)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	346	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

PTN23_HUMAN
NC score	0.027547 (rank : 44)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	646	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

FOXB2_MOUSE
NC score	0.025868 (rank : 45)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

NPAS2_MOUSE
NC score	0.025726 (rank : 46)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	132	Shared Neighborhood Hits	8
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

WNK2_HUMAN
NC score	0.023791 (rank : 47)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	1407	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MAP1B_HUMAN
NC score	0.022415 (rank : 48)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RC3H1_HUMAN
NC score	0.021660 (rank : 49)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

LEG3_MOUSE
NC score	0.019661 (rank : 50)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

RNF38_HUMAN
NC score	0.019184 (rank : 51)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

KCNK4_MOUSE
NC score	0.017230 (rank : 52)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

ZF106_MOUSE
NC score	0.016569 (rank : 53)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

SOX7_HUMAN
NC score	0.016499 (rank : 54)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

TIF1G_MOUSE
NC score	0.014973 (rank : 55)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

BNC1_HUMAN
NC score	0.013962 (rank : 56)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	460	Shared Neighborhood Hits	5
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

PLEC1_HUMAN
NC score	0.013084 (rank : 57)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	1326	Shared Neighborhood Hits	8
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MAST4_HUMAN
NC score	0.011069 (rank : 58)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CBPD_MOUSE
NC score	0.010243 (rank : 59)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

DNER_HUMAN
NC score	0.008269 (rank : 60)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	460	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

HXD10_MOUSE
NC score	0.006550 (rank : 61)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	P28359, Q91WU9	Gene names	Hoxd10, Hox-4.5, Hoxd-10
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4.5) (Hox-5.3).

KLF4_MOUSE
NC score	0.005794 (rank : 62)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	694	Shared Neighborhood Hits	4
SwissProt Accessions	Q60793, P70421	Gene names	Klf4, Ezf, Gklf, Zie
Domain Architecture
Description	Krueppel-like factor 4 (Gut-enriched krueppel-like factor) (Epithelial zinc-finger protein EZF).

GLIS3_HUMAN
NC score	0.002892 (rank : 63)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	758	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).