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Network neighborhood for query Sequence : MAD3_HUMAN

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MAD3_HUMAN
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAD3_HUMAN
θ value	8.81223e-72 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	4.24587e-58 (rank : 2)	NC score	0.972694 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD1_MOUSE
θ value	3.3877e-31 (rank : 3)	NC score	0.892487 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_HUMAN
θ value	1.02001e-27 (rank : 4)	NC score	0.890053 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD4_HUMAN
θ value	5.06226e-27 (rank : 5)	NC score	0.895203 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
θ value	5.06226e-27 (rank : 6)	NC score	0.891616 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MXI1_MOUSE
θ value	2.35151e-24 (rank : 7)	NC score	0.897169 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	1.99067e-23 (rank : 8)	NC score	0.902806 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MNT_MOUSE
θ value	9.59137e-10 (rank : 9)	NC score	0.519868 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	432	Shared Neighborhood Hits	41
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
θ value	1.63604e-09 (rank : 10)	NC score	0.499335 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	496	Shared Neighborhood Hits	39
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
θ value	5.81887e-07 (rank : 11)	NC score	0.386049 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	1.29631e-06 (rank : 12)	NC score	0.384205 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL2_HUMAN
θ value	0.00020696 (rank : 13)	NC score	0.322557 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

TFE3_HUMAN
θ value	0.000786445 (rank : 14)	NC score	0.273559 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

USF2_MOUSE
θ value	0.00509761 (rank : 15)	NC score	0.314071 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	173	Shared Neighborhood Hits	46
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

SRBP1_MOUSE
θ value	0.0113563 (rank : 16)	NC score	0.171002 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	384	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

USF2_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.313247 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MITF_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.255856 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.0563607 (rank : 19)	NC score	0.246156 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MYCL1_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.295018 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MD1L1_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.055999 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

RABE2_MOUSE
θ value	0.0961366 (rank : 22)	NC score	0.063879 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	598	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

BPAEA_MOUSE
θ value	0.125558 (rank : 23)	NC score	0.049777 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	1480	Shared Neighborhood Hits	44
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NEK11_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.007302 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	1043	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

ANKR6_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.015527 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

KIF5C_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.038530 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	1040	Shared Neighborhood Hits	41
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MYCL1_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.292473 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

CP135_MOUSE
θ value	0.279714 (rank : 28)	NC score	0.041583 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	1278	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TACC2_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.057029 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	856	Shared Neighborhood Hits	35
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CT2NL_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.043133 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GOGA5_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.038832 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	1434	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

SRBP1_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.150475 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CCD96_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.068215 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	704	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.077033 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	595	Shared Neighborhood Hits	36
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

TACC2_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.055503 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	774	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ZWINT_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.063631 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

AZI1_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.052878 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	990	Shared Neighborhood Hits	41
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CROCC_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.048497 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	1409	Shared Neighborhood Hits	45
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CYLN2_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.043426 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	1002	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

MAX_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.310358 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

RCOR3_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.039831 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RCOR3_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.042309 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

TFEB_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.211619 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.283053 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.284224 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

BHLH2_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.139083 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH3_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.151486 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

ARHGC_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.018228 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BHLH3_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.143988 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

MAX_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.303550 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

BHLH2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.127778 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH8_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.057991 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

KIF5C_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.036760 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	974	Shared Neighborhood Hits	41
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

ZGPAT_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.028752 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

BMAL1_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.089841 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.088454 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MYCN_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.256197 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.257458 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

PLEC1_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.040932 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	1326	Shared Neighborhood Hits	47
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

TFEB_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.211359 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

ARNT2_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.072784 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.073191 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

CCD21_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.041241 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	1228	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CYLN2_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.041908 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	1004	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

HES2_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.044445 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HIP1_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.042177 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	1016	Shared Neighborhood Hits	40
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MACF4_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.031820 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SYNE1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.031367 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CENPF_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.040604 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	1932	Shared Neighborhood Hits	45
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CING_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.045607 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	1432	Shared Neighborhood Hits	44
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CROCC_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.045570 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	1460	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

IFT81_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.034083 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	959	Shared Neighborhood Hits	33
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

LIPB2_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.031992 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MY18A_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.031499 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	1929	Shared Neighborhood Hits	45
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RIMB1_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.031649 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	1376	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TPR_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.033890 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	1921	Shared Neighborhood Hits	42
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

YAP1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.011746 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

AMOL2_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.035288 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	591	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ARHGC_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.016162 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARNT_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.085911 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.078608 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BRPF1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.011473 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	259	Shared Neighborhood Hits	7
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

FIGLA_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.054390 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

SRBP2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.177631 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

STIM1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.026225 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	665	Shared Neighborhood Hits	31
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

CCDC3_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.017022 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

HIP1R_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.040427 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	809	Shared Neighborhood Hits	37
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

K1802_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.007157 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	1596	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MY18B_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.029088 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	1299	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH6_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.026793 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	1501	Shared Neighborhood Hits	44
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SNW1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.026437 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.026225 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

BHLH8_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.061209 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

HES1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.093307 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.093715 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES4_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.072754 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HEY2_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.050810 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.050924 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MLX_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.077650 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.080152 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCB_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.145098 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MYCS_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.207112 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

TCFL5_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.153789 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFAP4_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.112162 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	289	Shared Neighborhood Hits	43
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

WBS14_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.062311 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

Hits sorted by NC score

MAD3_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.81223e-72 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.972694 (rank : 2)	θ value	4.24587e-58 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MXI1_HUMAN
NC score	0.902806 (rank : 3)	θ value	1.99067e-23 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
NC score	0.897169 (rank : 4)	θ value	2.35151e-24 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD4_HUMAN
NC score	0.895203 (rank : 5)	θ value	5.06226e-27 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD1_MOUSE
NC score	0.892487 (rank : 6)	θ value	3.3877e-31 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD4_MOUSE
NC score	0.891616 (rank : 7)	θ value	5.06226e-27 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD1_HUMAN
NC score	0.890053 (rank : 8)	θ value	1.02001e-27 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MNT_MOUSE
NC score	0.519868 (rank : 9)	θ value	9.59137e-10 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	432	Shared Neighborhood Hits	41
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.499335 (rank : 10)	θ value	1.63604e-09 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	496	Shared Neighborhood Hits	39
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
NC score	0.386049 (rank : 11)	θ value	5.81887e-07 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.384205 (rank : 12)	θ value	1.29631e-06 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL2_HUMAN
NC score	0.322557 (rank : 13)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

USF2_MOUSE
NC score	0.314071 (rank : 14)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	173	Shared Neighborhood Hits	46
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF2_HUMAN
NC score	0.313247 (rank : 15)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	155	Shared Neighborhood Hits	46
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MAX_HUMAN
NC score	0.310358 (rank : 16)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.303550 (rank : 17)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MYCL1_HUMAN
NC score	0.295018 (rank : 18)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.292473 (rank : 19)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

USF1_MOUSE
NC score	0.284224 (rank : 20)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.283053 (rank : 21)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFE3_HUMAN
NC score	0.273559 (rank : 22)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MYCN_MOUSE
NC score	0.257458 (rank : 23)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.256197 (rank : 24)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MITF_HUMAN
NC score	0.255856 (rank : 25)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.246156 (rank : 26)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFEB_HUMAN
NC score	0.211619 (rank : 27)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.211359 (rank : 28)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MYCS_MOUSE
NC score	0.207112 (rank : 29)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

SRBP2_HUMAN
NC score	0.177631 (rank : 30)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

SRBP1_MOUSE
NC score	0.171002 (rank : 31)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	384	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TCFL5_HUMAN
NC score	0.153789 (rank : 32)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

BHLH3_HUMAN
NC score	0.151486 (rank : 33)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

SRBP1_HUMAN
NC score	0.150475 (rank : 34)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MYCB_MOUSE
NC score	0.145098 (rank : 35)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

BHLH3_MOUSE
NC score	0.143988 (rank : 36)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_MOUSE
NC score	0.139083 (rank : 37)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH2_HUMAN
NC score	0.127778 (rank : 38)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

TFAP4_HUMAN
NC score	0.112162 (rank : 39)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	289	Shared Neighborhood Hits	43
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

HES1_MOUSE
NC score	0.093715 (rank : 40)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.093307 (rank : 41)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

BMAL1_HUMAN
NC score	0.089841 (rank : 42)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.088454 (rank : 43)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ARNT_HUMAN
NC score	0.085911 (rank : 44)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MLX_MOUSE
NC score	0.080152 (rank : 45)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

ARNT_MOUSE
NC score	0.078608 (rank : 46)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MLX_HUMAN
NC score	0.077650 (rank : 47)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

CCD96_HUMAN
NC score	0.077033 (rank : 48)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	595	Shared Neighborhood Hits	36
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ARNT2_MOUSE
NC score	0.073191 (rank : 49)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.072784 (rank : 50)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

HES4_HUMAN
NC score	0.072754 (rank : 51)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

CCD96_MOUSE
NC score	0.068215 (rank : 52)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	704	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RABE2_MOUSE
NC score	0.063879 (rank : 53)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	598	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

ZWINT_HUMAN
NC score	0.063631 (rank : 54)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

WBS14_HUMAN
NC score	0.062311 (rank : 55)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

BHLH8_MOUSE
NC score	0.061209 (rank : 56)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_HUMAN
NC score	0.057991 (rank : 57)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

TACC2_HUMAN
NC score	0.057029 (rank : 58)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	856	Shared Neighborhood Hits	35
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

MD1L1_HUMAN
NC score	0.055999 (rank : 59)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

TACC2_MOUSE
NC score	0.055503 (rank : 60)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	774	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

FIGLA_HUMAN
NC score	0.054390 (rank : 61)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

AZI1_MOUSE
NC score	0.052878 (rank : 62)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	990	Shared Neighborhood Hits	41
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

HEY2_MOUSE
NC score	0.050924 (rank : 63)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY2_HUMAN
NC score	0.050810 (rank : 64)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

BPAEA_MOUSE
NC score	0.049777 (rank : 65)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	1480	Shared Neighborhood Hits	44
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CROCC_HUMAN
NC score	0.048497 (rank : 66)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	1409	Shared Neighborhood Hits	45
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CING_MOUSE
NC score	0.045607 (rank : 67)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	1432	Shared Neighborhood Hits	44
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CROCC_MOUSE
NC score	0.045570 (rank : 68)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	1460	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HES2_MOUSE
NC score	0.044445 (rank : 69)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

CYLN2_MOUSE
NC score	0.043426 (rank : 70)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	1002	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CT2NL_MOUSE
NC score	0.043133 (rank : 71)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RCOR3_MOUSE
NC score	0.042309 (rank : 72)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

HIP1_HUMAN
NC score	0.042177 (rank : 73)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	1016	Shared Neighborhood Hits	40
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CYLN2_HUMAN
NC score	0.041908 (rank : 74)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	1004	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CP135_MOUSE
NC score	0.041583 (rank : 75)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	1278	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCD21_HUMAN
NC score	0.041241 (rank : 76)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	1228	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

PLEC1_HUMAN
NC score	0.040932 (rank : 77)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	1326	Shared Neighborhood Hits	47
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CENPF_HUMAN
NC score	0.040604 (rank : 78)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	1932	Shared Neighborhood Hits	45
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HIP1R_HUMAN
NC score	0.040427 (rank : 79)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	809	Shared Neighborhood Hits	37
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

RCOR3_HUMAN
NC score	0.039831 (rank : 80)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

GOGA5_MOUSE
NC score	0.038832 (rank : 81)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	1434	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KIF5C_MOUSE
NC score	0.038530 (rank : 82)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	1040	Shared Neighborhood Hits	41
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_HUMAN
NC score	0.036760 (rank : 83)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	974	Shared Neighborhood Hits	41
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

AMOL2_MOUSE
NC score	0.035288 (rank : 84)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	591	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

IFT81_MOUSE
NC score	0.034083 (rank : 85)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	959	Shared Neighborhood Hits	33
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

TPR_HUMAN
NC score	0.033890 (rank : 86)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	1921	Shared Neighborhood Hits	42
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

LIPB2_MOUSE
NC score	0.031992 (rank : 87)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MACF4_HUMAN
NC score	0.031820 (rank : 88)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

RIMB1_MOUSE
NC score	0.031649 (rank : 89)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	1376	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MY18A_HUMAN
NC score	0.031499 (rank : 90)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	1929	Shared Neighborhood Hits	45
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SYNE1_HUMAN
NC score	0.031367 (rank : 91)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MY18B_HUMAN
NC score	0.029088 (rank : 92)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	1299	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ZGPAT_MOUSE
NC score	0.028752 (rank : 93)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

MYH6_MOUSE
NC score	0.026793 (rank : 94)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	1501	Shared Neighborhood Hits	44
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SNW1_HUMAN
NC score	0.026437 (rank : 95)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

STIM1_HUMAN
NC score	0.026225 (rank : 96)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	665	Shared Neighborhood Hits	31
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SNW1_MOUSE
NC score	0.026225 (rank : 97)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

ARHGC_MOUSE
NC score	0.018228 (rank : 98)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CCDC3_HUMAN
NC score	0.017022 (rank : 99)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

ARHGC_HUMAN
NC score	0.016162 (rank : 100)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ANKR6_HUMAN
NC score	0.015527 (rank : 101)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	439	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

YAP1_MOUSE
NC score	0.011746 (rank : 102)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

BRPF1_HUMAN
NC score	0.011473 (rank : 103)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	259	Shared Neighborhood Hits	7
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

NEK11_HUMAN
NC score	0.007302 (rank : 104)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	1043	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

K1802_MOUSE
NC score	0.007157 (rank : 105)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	1596	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.