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Network neighborhood for query Sequence : MYCL2_HUMAN

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MYCL2_HUMAN
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYCL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_HUMAN
θ value	1.13238e-127 (rank : 2)	NC score	0.944511 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	1.2549e-118 (rank : 3)	NC score	0.938542 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
θ value	4.43474e-23 (rank : 4)	NC score	0.745339 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
θ value	7.56453e-23 (rank : 5)	NC score	0.743515 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	2.27762e-19 (rank : 6)	NC score	0.716184 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_MOUSE
θ value	1.47631e-18 (rank : 7)	NC score	0.712192 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	37
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	1.63225e-17 (rank : 8)	NC score	0.715749 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MAX_MOUSE
θ value	1.87187e-05 (rank : 9)	NC score	0.473922 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	139	Shared Neighborhood Hits	36
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MAX_HUMAN
θ value	3.19293e-05 (rank : 10)	NC score	0.477860 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAD3_HUMAN
θ value	0.00020696 (rank : 11)	NC score	0.322557 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	0.000461057 (rank : 12)	NC score	0.311234 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MYCB_MOUSE
θ value	0.000602161 (rank : 13)	NC score	0.563294 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MXI1_MOUSE
θ value	0.000786445 (rank : 14)	NC score	0.343227 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

WBS14_HUMAN
θ value	0.00228821 (rank : 15)	NC score	0.184373 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	273	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MXI1_HUMAN
θ value	0.00298849 (rank : 16)	NC score	0.331716 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD4_HUMAN
θ value	0.00509761 (rank : 17)	NC score	0.308661 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
θ value	0.0148317 (rank : 18)	NC score	0.276291 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD1_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.219959 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

NDF2_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.088897 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	0.0431538 (rank : 21)	NC score	0.088414 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

TFE3_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.214758 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.195983 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	27
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.0961366 (rank : 24)	NC score	0.193340 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

KIF5C_HUMAN
θ value	0.125558 (rank : 25)	NC score	0.019221 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	974	Shared Neighborhood Hits	8
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

USF2_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.225708 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	35
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.125558 (rank : 27)	NC score	0.226476 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

KIF5C_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.018562 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

FIGLA_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.202124 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

WBS14_MOUSE
θ value	0.365318 (rank : 30)	NC score	0.117644 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

NFH_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.021560 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	2247	Shared Neighborhood Hits	22
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SIGIR_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.029775 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

NDF1_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.059692 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	209	Shared Neighborhood Hits	18
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

T22D2_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.031045 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TJAP1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.026434 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TITIN_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.002373 (rank : 94)
Query Neighborhood Hits	63	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FIGLA_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.191538 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

TMAP1_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.057720 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

MELPH_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.022230 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

NDF1_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.056101 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

RBM6_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.019999 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

TFEB_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.155368 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	25
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.156604 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MINT_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.020878 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	1291	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST3_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.007965 (rank : 91)
Query Neighborhood Hits	63	Target Neighborhood Hits	772	Shared Neighborhood Hits	8
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PDXL2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.017674 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SCN3A_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.005454 (rank : 92)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SRRM2_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.011645 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	1296	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ARNT_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.091801 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.089262 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	26
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BHLH8_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.135029 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.142936 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

FOXGB_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.004143 (rank : 93)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

GLU2B_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.012874 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

IF2P_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.010188 (rank : 87)
Query Neighborhood Hits	63	Target Neighborhood Hits	889	Shared Neighborhood Hits	8
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MLL3_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.009788 (rank : 88)
Query Neighborhood Hits	63	Target Neighborhood Hits	1399	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

U2AFL_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.010321 (rank : 86)
Query Neighborhood Hits	63	Target Neighborhood Hits	503	Shared Neighborhood Hits	7
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

GGA3_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.008336 (rank : 89)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HAND1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.077417 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.081872 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HAND2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.098406 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.098406 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

NCOR1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.008229 (rank : 90)
Query Neighborhood Hits	63	Target Neighborhood Hits	521	Shared Neighborhood Hits	5
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

ARNT2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.076119 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.076638 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	23
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ASCL1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.100564 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.088775 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL2_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.063083 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ASCL2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.092801 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ATOH1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052450 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.052211 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

BHLH3_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.053577 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

MAD1_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.164398 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	68	Shared Neighborhood Hits	20
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MLX_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.165798 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.166920 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	22
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MNT_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.205997 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	496	Shared Neighborhood Hits	31
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.213227 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	432	Shared Neighborhood Hits	32
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NGN2_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.054975 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.053465 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.073218 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

NGN3_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.054883 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

PTF1A_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.089601 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.087364 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SCX_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.072438 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

SRBP1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.127698 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.119167 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	384	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.137927 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	133	Shared Neighborhood Hits	30
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TFAP4_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.149720 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TWST1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.076583 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.076503 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

TWST2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.081713 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.081838 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

USF1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.206737 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.208848 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

Hits sorted by NC score

MYCL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_HUMAN
NC score	0.944511 (rank : 2)	θ value	1.13238e-127 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.938542 (rank : 3)	θ value	1.2549e-118 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
NC score	0.745339 (rank : 4)	θ value	4.43474e-23 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.743515 (rank : 5)	θ value	7.56453e-23 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.716184 (rank : 6)	θ value	2.27762e-19 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_HUMAN
NC score	0.715749 (rank : 7)	θ value	1.63225e-17 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
NC score	0.712192 (rank : 8)	θ value	1.47631e-18 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	37
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCB_MOUSE
NC score	0.563294 (rank : 9)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
NC score	0.477860 (rank : 10)	θ value	3.19293e-05 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.473922 (rank : 11)	θ value	1.87187e-05 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	139	Shared Neighborhood Hits	36
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MXI1_MOUSE
NC score	0.343227 (rank : 12)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
NC score	0.331716 (rank : 13)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_HUMAN
NC score	0.322557 (rank : 14)	θ value	0.00020696 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.311234 (rank : 15)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_HUMAN
NC score	0.308661 (rank : 16)	θ value	0.00509761 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
NC score	0.276291 (rank : 17)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

USF2_MOUSE
NC score	0.226476 (rank : 18)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF2_HUMAN
NC score	0.225708 (rank : 19)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	35
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MAD1_MOUSE
NC score	0.219959 (rank : 20)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

TFE3_HUMAN
NC score	0.214758 (rank : 21)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MNT_MOUSE
NC score	0.213227 (rank : 22)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	432	Shared Neighborhood Hits	32
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

USF1_MOUSE
NC score	0.208848 (rank : 23)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.206737 (rank : 24)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MNT_HUMAN
NC score	0.205997 (rank : 25)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	496	Shared Neighborhood Hits	31
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

FIGLA_HUMAN
NC score	0.202124 (rank : 26)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MITF_HUMAN
NC score	0.195983 (rank : 27)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	27
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.193340 (rank : 28)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

FIGLA_MOUSE
NC score	0.191538 (rank : 29)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

WBS14_HUMAN
NC score	0.184373 (rank : 30)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	273	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MLX_MOUSE
NC score	0.166920 (rank : 31)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	22
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.165798 (rank : 32)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MAD1_HUMAN
NC score	0.164398 (rank : 33)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	68	Shared Neighborhood Hits	20
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

TFEB_MOUSE
NC score	0.156604 (rank : 34)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.155368 (rank : 35)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	25
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFAP4_HUMAN
NC score	0.149720 (rank : 36)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

BHLH8_MOUSE
NC score	0.142936 (rank : 37)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

SRBP2_HUMAN
NC score	0.137927 (rank : 38)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	63	Target Neighborhood Hits	133	Shared Neighborhood Hits	30
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

BHLH8_HUMAN
NC score	0.135029 (rank : 39)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

SRBP1_HUMAN
NC score	0.127698 (rank : 40)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
NC score	0.119167 (rank : 41)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	63	Target Neighborhood Hits	384	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

WBS14_MOUSE
NC score	0.117644 (rank : 42)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ASCL1_HUMAN
NC score	0.100564 (rank : 43)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

HAND2_HUMAN
NC score	0.098406 (rank : 44)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.098406 (rank : 45)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

ASCL2_MOUSE
NC score	0.092801 (rank : 46)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ARNT_HUMAN
NC score	0.091801 (rank : 47)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

PTF1A_HUMAN
NC score	0.089601 (rank : 48)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ARNT_MOUSE
NC score	0.089262 (rank : 49)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	26
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NDF2_HUMAN
NC score	0.088897 (rank : 50)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

ASCL1_MOUSE
NC score	0.088775 (rank : 51)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

NDF2_MOUSE
NC score	0.088414 (rank : 52)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

PTF1A_MOUSE
NC score	0.087364 (rank : 53)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

HAND1_MOUSE
NC score	0.081872 (rank : 54)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

TWST2_MOUSE
NC score	0.081838 (rank : 55)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.081713 (rank : 56)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

HAND1_HUMAN
NC score	0.077417 (rank : 57)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

ARNT2_MOUSE
NC score	0.076638 (rank : 58)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	23
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

TWST1_HUMAN
NC score	0.076583 (rank : 59)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.076503 (rank : 60)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	63	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ARNT2_HUMAN
NC score	0.076119 (rank : 61)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NGN3_HUMAN
NC score	0.073218 (rank : 62)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

SCX_MOUSE
NC score	0.072438 (rank : 63)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

ASCL2_HUMAN
NC score	0.063083 (rank : 64)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

NDF1_MOUSE
NC score	0.059692 (rank : 65)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	209	Shared Neighborhood Hits	18
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

TMAP1_MOUSE
NC score	0.057720 (rank : 66)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

NDF1_HUMAN
NC score	0.056101 (rank : 67)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NGN2_HUMAN
NC score	0.054975 (rank : 68)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN3_MOUSE
NC score	0.054883 (rank : 69)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

BHLH3_HUMAN
NC score	0.053577 (rank : 70)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

NGN2_MOUSE
NC score	0.053465 (rank : 71)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

ATOH1_HUMAN
NC score	0.052450 (rank : 72)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
NC score	0.052211 (rank : 73)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

T22D2_HUMAN
NC score	0.031045 (rank : 74)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SIGIR_HUMAN
NC score	0.029775 (rank : 75)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

TJAP1_MOUSE
NC score	0.026434 (rank : 76)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MELPH_HUMAN
NC score	0.022230 (rank : 77)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

NFH_MOUSE
NC score	0.021560 (rank : 78)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	2247	Shared Neighborhood Hits	22
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MINT_HUMAN
NC score	0.020878 (rank : 79)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	1291	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RBM6_HUMAN
NC score	0.019999 (rank : 80)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

KIF5C_HUMAN
NC score	0.019221 (rank : 81)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	974	Shared Neighborhood Hits	8
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
NC score	0.018562 (rank : 82)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PDXL2_HUMAN
NC score	0.017674 (rank : 83)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

GLU2B_MOUSE
NC score	0.012874 (rank : 84)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SRRM2_HUMAN
NC score	0.011645 (rank : 85)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	1296	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

U2AFL_HUMAN
NC score	0.010321 (rank : 86)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	503	Shared Neighborhood Hits	7
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

IF2P_HUMAN
NC score	0.010188 (rank : 87)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	889	Shared Neighborhood Hits	8
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MLL3_MOUSE
NC score	0.009788 (rank : 88)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	1399	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

GGA3_MOUSE
NC score	0.008336 (rank : 89)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

NCOR1_MOUSE
NC score	0.008229 (rank : 90)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	521	Shared Neighborhood Hits	5
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

MYST3_HUMAN
NC score	0.007965 (rank : 91)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	772	Shared Neighborhood Hits	8
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

SCN3A_HUMAN
NC score	0.005454 (rank : 92)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

FOXGB_HUMAN
NC score	0.004143 (rank : 93)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

TITIN_HUMAN
NC score	0.002373 (rank : 94)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).