Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MYF6_HUMAN

For an explanation of this page, click here

MYF6_HUMAN
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYF6_MOUSE
θ value	1.30163e-107 (rank : 1)	NC score	0.997866 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	72	Shared Neighborhood Hits	69
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYF6_HUMAN
θ value	2.22025e-107 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYOG_MOUSE
θ value	3.3877e-31 (rank : 3)	NC score	0.898127 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYOG_HUMAN
θ value	4.57862e-28 (rank : 4)	NC score	0.895886 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYF5_HUMAN
θ value	2.96777e-27 (rank : 5)	NC score	0.875816 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	1.6852e-22 (rank : 6)	NC score	0.865137 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_MOUSE
θ value	2.43343e-21 (rank : 7)	NC score	0.850711 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOD1_HUMAN
θ value	5.42112e-21 (rank : 8)	NC score	0.841764 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

PTF1A_HUMAN
θ value	8.40245e-06 (rank : 9)	NC score	0.499069 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
θ value	8.40245e-06 (rank : 10)	NC score	0.494130 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

FIGLA_HUMAN
θ value	4.1701e-05 (rank : 11)	NC score	0.507884 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

TWST2_MOUSE
θ value	9.29e-05 (rank : 12)	NC score	0.474176 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.473149 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST1_HUMAN
θ value	0.000158464 (rank : 14)	NC score	0.492276 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	60
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	0.000158464 (rank : 15)	NC score	0.492042 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ASCL3_MOUSE
θ value	0.000461057 (rank : 16)	NC score	0.473622 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

FIGLA_MOUSE
θ value	0.000602161 (rank : 17)	NC score	0.489860 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

ASCL3_HUMAN
θ value	0.00175202 (rank : 18)	NC score	0.456615 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

HAND2_HUMAN
θ value	0.00665767 (rank : 19)	NC score	0.399438 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	0.00665767 (rank : 20)	NC score	0.399438 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

ASCL2_HUMAN
θ value	0.0148317 (rank : 21)	NC score	0.438295 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

NGN1_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.376846 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	0.0148317 (rank : 23)	NC score	0.379200 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

TAL1_HUMAN
θ value	0.0148317 (rank : 24)	NC score	0.411339 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	0.0193708 (rank : 25)	NC score	0.414882 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TFAP4_HUMAN
θ value	0.0193708 (rank : 26)	NC score	0.338231 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

SCX_MOUSE
θ value	0.0252991 (rank : 27)	NC score	0.397186 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

MYC_MOUSE
θ value	0.0330416 (rank : 28)	NC score	0.204970 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

ASCL2_MOUSE
θ value	0.0431538 (rank : 29)	NC score	0.443237 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	98	Shared Neighborhood Hits	55
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

NDF2_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.333428 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	54
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	0.0431538 (rank : 31)	NC score	0.333022 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF4_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.322899 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	0.0431538 (rank : 33)	NC score	0.323938 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NGN3_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.377461 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

NGN3_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.365454 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

SRBP2_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.117255 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

HAND1_MOUSE
θ value	0.0736092 (rank : 37)	NC score	0.364450 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

NDF1_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.317905 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	186	Shared Neighborhood Hits	55
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	0.0961366 (rank : 39)	NC score	0.315712 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	209	Shared Neighborhood Hits	55
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NGN2_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.339503 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	0.0961366 (rank : 41)	NC score	0.340572 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

TFE2_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.188429 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

ASCL1_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.404055 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL1_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.408456 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

BHLH8_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.388323 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	0.163984 (rank : 46)	NC score	0.387633 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MNT_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.180171 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	496	Shared Neighborhood Hits	40
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	0.163984 (rank : 48)	NC score	0.186301 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	432	Shared Neighborhood Hits	39
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

HAND1_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.353730 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

LYL1_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.373025 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.369811 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

HTF4_MOUSE
θ value	0.813845 (rank : 52)	NC score	0.173772 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

HES1_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.100331 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.100453 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HTF4_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.165197 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

NBEAL_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.019476 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

TFE2_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.170617 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

ITF2_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.166093 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	168	Shared Neighborhood Hits	38
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.165729 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	154	Shared Neighborhood Hits	38
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

TCF15_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.347390 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

MYC_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.163252 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

SRBP1_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.085642 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

HES4_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.071754 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

TCF15_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.308134 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

EGLN2_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.014301 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

EMID1_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.007068 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

MITF_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.048296 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

EP400_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.008869 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	556	Shared Neighborhood Hits	4
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SRBP1_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.083325 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

FRS2_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.012651 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

MAX_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.115548 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MITF_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.044777 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MYCL1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.079802 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

SPTN2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.001663 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

ATOH1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.252073 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	49
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.256765 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

BHLH4_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.189665 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.184172 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

HEN1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.287337 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.284167 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.273411 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.272499 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

ID1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.138854 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.107364 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	64	Shared Neighborhood Hits	37
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.068183 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.061988 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID4_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.124192 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ID4_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.120177 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

MAX_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.119068 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MUSC_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.243307 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.247699 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MYCL1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.071310 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	123	Shared Neighborhood Hits	34
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.090744 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.093267 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.094001 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

NDF6_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.236152 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.234911 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

OLIG1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.170421 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.167400 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.169059 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.168838 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.161841 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.164015 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

TAL2_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.302585 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.303028 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF21_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.239073 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.237721 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

Hits sorted by NC score

MYF6_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.22025e-107 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
NC score	0.997866 (rank : 2)	θ value	1.30163e-107 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	72	Shared Neighborhood Hits	69
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYOG_MOUSE
NC score	0.898127 (rank : 3)	θ value	3.3877e-31 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYOG_HUMAN
NC score	0.895886 (rank : 4)	θ value	4.57862e-28 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYF5_HUMAN
NC score	0.875816 (rank : 5)	θ value	2.96777e-27 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
NC score	0.865137 (rank : 6)	θ value	1.6852e-22 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_MOUSE
NC score	0.850711 (rank : 7)	θ value	2.43343e-21 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOD1_HUMAN
NC score	0.841764 (rank : 8)	θ value	5.42112e-21 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

FIGLA_HUMAN
NC score	0.507884 (rank : 9)	θ value	4.1701e-05 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

PTF1A_HUMAN
NC score	0.499069 (rank : 10)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
NC score	0.494130 (rank : 11)	θ value	8.40245e-06 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

TWST1_HUMAN
NC score	0.492276 (rank : 12)	θ value	0.000158464 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	60
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.492042 (rank : 13)	θ value	0.000158464 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

FIGLA_MOUSE
NC score	0.489860 (rank : 14)	θ value	0.000602161 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

TWST2_MOUSE
NC score	0.474176 (rank : 15)	θ value	9.29e-05 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

ASCL3_MOUSE
NC score	0.473622 (rank : 16)	θ value	0.000461057 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

TWST2_HUMAN
NC score	0.473149 (rank : 17)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

ASCL3_HUMAN
NC score	0.456615 (rank : 18)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ASCL2_MOUSE
NC score	0.443237 (rank : 19)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	98	Shared Neighborhood Hits	55
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ASCL2_HUMAN
NC score	0.438295 (rank : 20)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

TAL1_MOUSE
NC score	0.414882 (rank : 21)	θ value	0.0193708 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL1_HUMAN
NC score	0.411339 (rank : 22)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

ASCL1_MOUSE
NC score	0.408456 (rank : 23)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL1_HUMAN
NC score	0.404055 (rank : 24)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

HAND2_HUMAN
NC score	0.399438 (rank : 25)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.399438 (rank : 26)	θ value	0.00665767 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

SCX_MOUSE
NC score	0.397186 (rank : 27)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

BHLH8_HUMAN
NC score	0.388323 (rank : 28)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
NC score	0.387633 (rank : 29)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

NGN1_MOUSE
NC score	0.379200 (rank : 30)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN3_MOUSE
NC score	0.377461 (rank : 31)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

NGN1_HUMAN
NC score	0.376846 (rank : 32)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

LYL1_HUMAN
NC score	0.373025 (rank : 33)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
NC score	0.369811 (rank : 34)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

NGN3_HUMAN
NC score	0.365454 (rank : 35)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

HAND1_MOUSE
NC score	0.364450 (rank : 36)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HAND1_HUMAN
NC score	0.353730 (rank : 37)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

TCF15_MOUSE
NC score	0.347390 (rank : 38)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

NGN2_MOUSE
NC score	0.340572 (rank : 39)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN2_HUMAN
NC score	0.339503 (rank : 40)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

TFAP4_HUMAN
NC score	0.338231 (rank : 41)	θ value	0.0193708 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

NDF2_HUMAN
NC score	0.333428 (rank : 42)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	54
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.333022 (rank : 43)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF4_MOUSE
NC score	0.323938 (rank : 44)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF4_HUMAN
NC score	0.322899 (rank : 45)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF1_HUMAN
NC score	0.317905 (rank : 46)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	186	Shared Neighborhood Hits	55
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
NC score	0.315712 (rank : 47)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	209	Shared Neighborhood Hits	55
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

TCF15_HUMAN
NC score	0.308134 (rank : 48)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TAL2_MOUSE
NC score	0.303028 (rank : 49)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TAL2_HUMAN
NC score	0.302585 (rank : 50)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

HEN1_HUMAN
NC score	0.287337 (rank : 51)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
NC score	0.284167 (rank : 52)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
NC score	0.273411 (rank : 53)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.272499 (rank : 54)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

ATOH1_MOUSE
NC score	0.256765 (rank : 55)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ATOH1_HUMAN
NC score	0.252073 (rank : 56)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	49
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

MUSC_MOUSE
NC score	0.247699 (rank : 57)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MUSC_HUMAN
NC score	0.243307 (rank : 58)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	46
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

TCF21_HUMAN
NC score	0.239073 (rank : 59)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
NC score	0.237721 (rank : 60)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

NDF6_HUMAN
NC score	0.236152 (rank : 61)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
NC score	0.234911 (rank : 62)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

MYC_MOUSE
NC score	0.204970 (rank : 63)	θ value	0.0330416 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

BHLH4_HUMAN
NC score	0.189665 (rank : 64)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

TFE2_HUMAN
NC score	0.188429 (rank : 65)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

MNT_MOUSE
NC score	0.186301 (rank : 66)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	432	Shared Neighborhood Hits	39
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

BHLH4_MOUSE
NC score	0.184172 (rank : 67)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

MNT_HUMAN
NC score	0.180171 (rank : 68)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	496	Shared Neighborhood Hits	40
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

HTF4_MOUSE
NC score	0.173772 (rank : 69)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

TFE2_MOUSE
NC score	0.170617 (rank : 70)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

OLIG1_HUMAN
NC score	0.170421 (rank : 71)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG2_HUMAN
NC score	0.169059 (rank : 72)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
NC score	0.168838 (rank : 73)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG1_MOUSE
NC score	0.167400 (rank : 74)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

ITF2_HUMAN
NC score	0.166093 (rank : 75)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	168	Shared Neighborhood Hits	38
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
NC score	0.165729 (rank : 76)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	154	Shared Neighborhood Hits	38
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

HTF4_HUMAN
NC score	0.165197 (rank : 77)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

OLIG3_MOUSE
NC score	0.164015 (rank : 78)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

MYC_HUMAN
NC score	0.163252 (rank : 79)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

OLIG3_HUMAN
NC score	0.161841 (rank : 80)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

ID1_HUMAN
NC score	0.138854 (rank : 81)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID4_HUMAN
NC score	0.124192 (rank : 82)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ID4_MOUSE
NC score	0.120177 (rank : 83)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

MAX_MOUSE
NC score	0.119068 (rank : 84)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

SRBP2_HUMAN
NC score	0.117255 (rank : 85)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MAX_HUMAN
NC score	0.115548 (rank : 86)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

ID1_MOUSE
NC score	0.107364 (rank : 87)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	64	Shared Neighborhood Hits	37
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

HES1_MOUSE
NC score	0.100453 (rank : 88)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.100331 (rank : 89)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

MYCS_MOUSE
NC score	0.094001 (rank : 90)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCN_MOUSE
NC score	0.093267 (rank : 91)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.090744 (rank : 92)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

SRBP1_MOUSE
NC score	0.085642 (rank : 93)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_HUMAN
NC score	0.083325 (rank : 94)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MYCL1_HUMAN
NC score	0.079802 (rank : 95)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	37
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

HES4_HUMAN
NC score	0.071754 (rank : 96)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

MYCL1_MOUSE
NC score	0.071310 (rank : 97)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	123	Shared Neighborhood Hits	34
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

ID2_HUMAN
NC score	0.068183 (rank : 98)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID2_MOUSE
NC score	0.061988 (rank : 99)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

MITF_HUMAN
NC score	0.048296 (rank : 100)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.044777 (rank : 101)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NBEAL_HUMAN
NC score	0.019476 (rank : 102)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

EGLN2_HUMAN
NC score	0.014301 (rank : 103)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

FRS2_MOUSE
NC score	0.012651 (rank : 104)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

EP400_HUMAN
NC score	0.008869 (rank : 105)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	556	Shared Neighborhood Hits	4
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EMID1_MOUSE
NC score	0.007068 (rank : 106)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

SPTN2_HUMAN
NC score	0.001663 (rank : 107)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).