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Network neighborhood for query Sequence : XRN1_MOUSE

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XRN1_MOUSE
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

XRN1_HUMAN
θ value	0 (rank : 1)	NC score	0.990918 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

XRN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

XRN2_HUMAN
θ value	2.5521e-87 (rank : 3)	NC score	0.839006 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

XRN2_MOUSE
θ value	2.5521e-87 (rank : 4)	NC score	0.838761 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

YLPM1_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.039568 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

TP53B_MOUSE
θ value	0.279714 (rank : 6)	NC score	0.033143 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TMC2_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.026882 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

FOS_HUMAN
θ value	0.62314 (rank : 8)	NC score	0.040342 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

REXO4_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.037008 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

FOS_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.039149 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

IMP4_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.057647 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHZ7, Q3U8H6, Q8CI42, Q9CWN6, Q9CYT5	Gene names	Imp4, D1Wsu40e
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4).

CP053_MOUSE
θ value	1.06291 (rank : 12)	NC score	0.046920 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

JHD3D_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.018588 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

TAU_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.022723 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	502	Shared Neighborhood Hits	6
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

DZIP1_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.021903 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	675	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

LAP2A_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.025812 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

SYNG_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.026365 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

EHMT2_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.009999 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	498	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EURL_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.032083 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYK6, Q9H8C6	Gene names	EURL, C21orf7, C21orf91, YG81
Domain Architecture
Description	Protein EURL homolog.

GAB2_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.020092 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

MLL3_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.013790 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SDCG1_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.026104 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

AP3D1_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.020921 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	254	Shared Neighborhood Hits	6
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

CH3L1_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.022283 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P36222, P30923, Q8IVA4, Q96HI7	Gene names	CHI3L1
Domain Architecture
Description	Chitinase-3-like protein 1 precursor (Cartilage glycoprotein 39) (GP- 39) (39 kDa synovial protein) (HCgp-39) (YKL-40).

CPNE8_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.014873 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.014921 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

FAT2_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.007692 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

PININ_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.015267 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	753	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

BRD2_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.011855 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

NFH_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.009285 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	1242	Shared Neighborhood Hits	18
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOTC2_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.006963 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	1069	Shared Neighborhood Hits	9
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PGBM_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.005804 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	1113	Shared Neighborhood Hits	7
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PRGC2_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.020946 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SMC2_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.007419 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	1405	Shared Neighborhood Hits	13
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TULP1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.018209 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

TXLNA_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.009907 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	982	Shared Neighborhood Hits	8
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UBXD8_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.021447 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

ARNT_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.009829 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CDC20_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.007345 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

EEA1_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.003564 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	1796	Shared Neighborhood Hits	11
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FIBA_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.012531 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

NCOA6_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.012023 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	1202	Shared Neighborhood Hits	13
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TOP1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.015617 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

AP3D1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.017954 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

LYAR_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.019230 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

NOTC2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.006338 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

UDB11_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.009183 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

ATX1_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.013597 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CEBPZ_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.013767 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

CO4B_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.007615 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CP053_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.032412 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

DCC_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.003467 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	583	Shared Neighborhood Hits	5
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

ERIC1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.012879 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

HPCL_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.024652 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ83, Q9BV42, Q9P0A2	Gene names	HPCL, HPCL2, PHYH2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

JARD2_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.013420 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

SFR12_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.009287 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	486	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TUB_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.014240 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

ZC3H6_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.010486 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CELR1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.004717 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	613	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

DLX5_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.002694 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	434	Shared Neighborhood Hits	3
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

GP1BA_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.004679 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	407	Shared Neighborhood Hits	6
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

K1383_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.015188 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

NALD2_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.006503 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

TAF3_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.010340 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	568	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

Hits sorted by NC score

XRN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

XRN1_HUMAN
NC score	0.990918 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

XRN2_HUMAN
NC score	0.839006 (rank : 3)	θ value	2.5521e-87 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

XRN2_MOUSE
NC score	0.838761 (rank : 4)	θ value	2.5521e-87 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

IMP4_MOUSE
NC score	0.057647 (rank : 5)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHZ7, Q3U8H6, Q8CI42, Q9CWN6, Q9CYT5	Gene names	Imp4, D1Wsu40e
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4).

CP053_MOUSE
NC score	0.046920 (rank : 6)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

FOS_HUMAN
NC score	0.040342 (rank : 7)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

YLPM1_HUMAN
NC score	0.039568 (rank : 8)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

FOS_MOUSE
NC score	0.039149 (rank : 9)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

REXO4_HUMAN
NC score	0.037008 (rank : 10)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

TP53B_MOUSE
NC score	0.033143 (rank : 11)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CP053_HUMAN
NC score	0.032412 (rank : 12)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

EURL_HUMAN
NC score	0.032083 (rank : 13)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYK6, Q9H8C6	Gene names	EURL, C21orf7, C21orf91, YG81
Domain Architecture
Description	Protein EURL homolog.

TMC2_HUMAN
NC score	0.026882 (rank : 14)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

SYNG_HUMAN
NC score	0.026365 (rank : 15)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SDCG1_MOUSE
NC score	0.026104 (rank : 16)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

LAP2A_MOUSE
NC score	0.025812 (rank : 17)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

HPCL_HUMAN
NC score	0.024652 (rank : 18)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ83, Q9BV42, Q9P0A2	Gene names	HPCL, HPCL2, PHYH2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

TAU_MOUSE
NC score	0.022723 (rank : 19)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	502	Shared Neighborhood Hits	6
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CH3L1_HUMAN
NC score	0.022283 (rank : 20)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P36222, P30923, Q8IVA4, Q96HI7	Gene names	CHI3L1
Domain Architecture
Description	Chitinase-3-like protein 1 precursor (Cartilage glycoprotein 39) (GP- 39) (39 kDa synovial protein) (HCgp-39) (YKL-40).

DZIP1_HUMAN
NC score	0.021903 (rank : 21)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	675	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

UBXD8_HUMAN
NC score	0.021447 (rank : 22)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

PRGC2_HUMAN
NC score	0.020946 (rank : 23)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

AP3D1_HUMAN
NC score	0.020921 (rank : 24)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	254	Shared Neighborhood Hits	6
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

GAB2_HUMAN
NC score	0.020092 (rank : 25)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

LYAR_HUMAN
NC score	0.019230 (rank : 26)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

JHD3D_MOUSE
NC score	0.018588 (rank : 27)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

TULP1_HUMAN
NC score	0.018209 (rank : 28)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

AP3D1_MOUSE
NC score	0.017954 (rank : 29)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

TOP1_HUMAN
NC score	0.015617 (rank : 30)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

PININ_HUMAN
NC score	0.015267 (rank : 31)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	753	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

K1383_HUMAN
NC score	0.015188 (rank : 32)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

CPNE8_MOUSE
NC score	0.014921 (rank : 33)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_HUMAN
NC score	0.014873 (rank : 34)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

TUB_HUMAN
NC score	0.014240 (rank : 35)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

MLL3_HUMAN
NC score	0.013790 (rank : 36)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	1644	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CEBPZ_HUMAN
NC score	0.013767 (rank : 37)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

ATX1_MOUSE
NC score	0.013597 (rank : 38)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

JARD2_MOUSE
NC score	0.013420 (rank : 39)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

ERIC1_HUMAN
NC score	0.012879 (rank : 40)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

FIBA_HUMAN
NC score	0.012531 (rank : 41)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

NCOA6_HUMAN
NC score	0.012023 (rank : 42)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	1202	Shared Neighborhood Hits	13
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BRD2_HUMAN
NC score	0.011855 (rank : 43)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ZC3H6_MOUSE
NC score	0.010486 (rank : 44)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

TAF3_HUMAN
NC score	0.010340 (rank : 45)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	568	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

EHMT2_HUMAN
NC score	0.009999 (rank : 46)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	498	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TXLNA_HUMAN
NC score	0.009907 (rank : 47)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	982	Shared Neighborhood Hits	8
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ARNT_MOUSE
NC score	0.009829 (rank : 48)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SFR12_MOUSE
NC score	0.009287 (rank : 49)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	486	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

NFH_HUMAN
NC score	0.009285 (rank : 50)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	1242	Shared Neighborhood Hits	18
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UDB11_HUMAN
NC score	0.009183 (rank : 51)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

FAT2_HUMAN
NC score	0.007692 (rank : 52)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CO4B_MOUSE
NC score	0.007615 (rank : 53)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

SMC2_HUMAN
NC score	0.007419 (rank : 54)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	1405	Shared Neighborhood Hits	13
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CDC20_HUMAN
NC score	0.007345 (rank : 55)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

NOTC2_MOUSE
NC score	0.006963 (rank : 56)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	1069	Shared Neighborhood Hits	9
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NALD2_HUMAN
NC score	0.006503 (rank : 57)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3Q0	Gene names	NAALAD2
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (N- acetylated-alpha-linked acidic dipeptidase II) (NAALADase II).

NOTC2_HUMAN
NC score	0.006338 (rank : 58)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PGBM_HUMAN
NC score	0.005804 (rank : 59)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	1113	Shared Neighborhood Hits	7
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CELR1_HUMAN
NC score	0.004717 (rank : 60)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	613	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

GP1BA_HUMAN
NC score	0.004679 (rank : 61)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	407	Shared Neighborhood Hits	6
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

EEA1_HUMAN
NC score	0.003564 (rank : 62)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	1796	Shared Neighborhood Hits	11
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

DCC_HUMAN
NC score	0.003467 (rank : 63)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	583	Shared Neighborhood Hits	5
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DLX5_MOUSE
NC score	0.002694 (rank : 64)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	434	Shared Neighborhood Hits	3
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.