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Network neighborhood for query Sequence : HPCL_HUMAN

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HPCL_HUMAN
SwissProt Accessions	Q9UJ83, Q9BV42, Q9P0A2	Gene names	HPCL, HPCL2, PHYH2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HPCL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJ83, Q9BV42, Q9P0A2	Gene names	HPCL, HPCL2, PHYH2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

HPCL_MOUSE
θ value	0 (rank : 2)	NC score	0.997842 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXE0, Q543K1, Q9DAV1	Gene names	Hpcl, Phyh2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

PCTK3_HUMAN
θ value	1.38821 (rank : 3)	NC score	0.008708 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	827	Shared Neighborhood Hits	5
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

DPP10_HUMAN
θ value	1.81305 (rank : 4)	NC score	0.042312 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

PIGV_HUMAN
θ value	1.81305 (rank : 5)	NC score	0.060474 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUD9, Q5JYG7, Q5JYG8, Q5JYG9, Q9NX26	Gene names	PIGV
Domain Architecture	No domain graphic available
Description	GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V).

S4A7_MOUSE
θ value	1.81305 (rank : 6)	NC score	0.017154 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

DPP10_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.041705 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

KSR2_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.004776 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	920	Shared Neighborhood Hits	4
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

RBM4_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.010138 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

XRN1_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.026036 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

ANGL3_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.008024 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ARSJ_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.011561 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

PCTK3_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.004466 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	834	Shared Neighborhood Hits	4
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

XRN1_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.024652 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

Hits sorted by NC score

HPCL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJ83, Q9BV42, Q9P0A2	Gene names	HPCL, HPCL2, PHYH2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

HPCL_MOUSE
NC score	0.997842 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXE0, Q543K1, Q9DAV1	Gene names	Hpcl, Phyh2
Domain Architecture
Description	2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) (2-HPCL).

PIGV_HUMAN
NC score	0.060474 (rank : 3)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUD9, Q5JYG7, Q5JYG8, Q5JYG9, Q9NX26	Gene names	PIGV
Domain Architecture	No domain graphic available
Description	GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V).

DPP10_HUMAN
NC score	0.042312 (rank : 4)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP10_MOUSE
NC score	0.041705 (rank : 5)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

XRN1_HUMAN
NC score	0.026036 (rank : 6)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

XRN1_MOUSE
NC score	0.024652 (rank : 7)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

S4A7_MOUSE
NC score	0.017154 (rank : 8)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

ARSJ_MOUSE
NC score	0.011561 (rank : 9)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BM89, Q8BKG5, Q8BL46	Gene names	Arsj
Domain Architecture	No domain graphic available
Description	Arylsulfatase J precursor (EC 3.1.6.-) (ASJ).

RBM4_MOUSE
NC score	0.010138 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

PCTK3_HUMAN
NC score	0.008708 (rank : 11)	θ value	1.38821 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	827	Shared Neighborhood Hits	5
SwissProt Accessions	Q07002, Q5VXQ2, Q96F90	Gene names	PCTK3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).

ANGL3_MOUSE
NC score	0.008024 (rank : 12)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

KSR2_HUMAN
NC score	0.004776 (rank : 13)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	920	Shared Neighborhood Hits	4
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

PCTK3_MOUSE
NC score	0.004466 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	834	Shared Neighborhood Hits	4
SwissProt Accessions	Q04899	Gene names	Pctk3
Domain Architecture
Description	Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) (PCTAIRE- motif protein kinase 3).