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Network neighborhood for query Sequence : LAP2A_MOUSE

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LAP2A_MOUSE
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LAP2A_HUMAN
θ value	0 (rank : 1)	NC score	0.987922 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LAP2A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

LAP2B_MOUSE
θ value	6.95003e-85 (rank : 3)	NC score	0.925510 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q61029, Q61030, Q61031, Q61032	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms beta/delta/epsilon/gamma (Thymopoietin isoforms beta/delta/epsilon/gamma) (TP beta/delta/epsilon/gamma).

LAP2B_HUMAN
θ value	8.22888e-78 (rank : 4)	NC score	0.911662 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

EMD_HUMAN
θ value	0.00134147 (rank : 5)	NC score	0.291719 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P50402	Gene names	EMD, EDMD, STA
Domain Architecture
Description	Emerin.

EMD_MOUSE
θ value	0.00134147 (rank : 6)	NC score	0.298350 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O08579	Gene names	Emd, Sta
Domain Architecture
Description	Emerin.

MAN1_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.181885 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

FNBP2_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.026086 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	432	Shared Neighborhood Hits	4
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

LARP1_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.103346 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

CCNI_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.110410 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

M3K14_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.016276 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	889	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

SON_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.025164 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	957	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CN104_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.045630 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

SALL3_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.006184 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	1066	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

AT2C2_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.024909 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O75185	Gene names	KIAA0703
Domain Architecture	No domain graphic available
Description	Probable calcium-transporting ATPase KIAA0703 (EC 3.6.3.8).

HIPK1_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.009961 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

PASK_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.007399 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	867	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

XRN1_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.025812 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

MRCKB_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.005740 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	2180	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ZFP37_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.005419 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).

M3K14_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.011424 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	887	Shared Neighborhood Hits	8
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

FOXN1_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.010445 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	300	Shared Neighborhood Hits	3
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

HIPK1_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.008782 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

NKTR_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.010695 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RIMS2_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.010981 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

WBS14_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.019539 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

CCNI_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.063481 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

MRCKB_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.004814 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	2239	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PITX2_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.005696 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.005547 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	383	Shared Neighborhood Hits	3
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

SNIP_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.013894 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

VAV3_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.006755 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	398	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ZC3H3_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.013677 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

AKAP1_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.011391 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

ASXL1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.011758 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

DDX24_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.006405 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

SNPC4_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.009780 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	589	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TARA_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.007919 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

Hits sorted by NC score

LAP2A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

LAP2A_HUMAN
NC score	0.987922 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LAP2B_MOUSE
NC score	0.925510 (rank : 3)	θ value	6.95003e-85 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q61029, Q61030, Q61031, Q61032	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms beta/delta/epsilon/gamma (Thymopoietin isoforms beta/delta/epsilon/gamma) (TP beta/delta/epsilon/gamma).

LAP2B_HUMAN
NC score	0.911662 (rank : 4)	θ value	8.22888e-78 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

EMD_MOUSE
NC score	0.298350 (rank : 5)	θ value	0.00134147 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	O08579	Gene names	Emd, Sta
Domain Architecture
Description	Emerin.

EMD_HUMAN
NC score	0.291719 (rank : 6)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P50402	Gene names	EMD, EDMD, STA
Domain Architecture
Description	Emerin.

MAN1_HUMAN
NC score	0.181885 (rank : 7)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

CCNI_HUMAN
NC score	0.110410 (rank : 8)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

LARP1_HUMAN
NC score	0.103346 (rank : 9)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

CCNI_MOUSE
NC score	0.063481 (rank : 10)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

CN104_MOUSE
NC score	0.045630 (rank : 11)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

FNBP2_HUMAN
NC score	0.026086 (rank : 12)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	432	Shared Neighborhood Hits	4
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

XRN1_MOUSE
NC score	0.025812 (rank : 13)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

SON_MOUSE
NC score	0.025164 (rank : 14)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	957	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

AT2C2_HUMAN
NC score	0.024909 (rank : 15)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O75185	Gene names	KIAA0703
Domain Architecture	No domain graphic available
Description	Probable calcium-transporting ATPase KIAA0703 (EC 3.6.3.8).

WBS14_MOUSE
NC score	0.019539 (rank : 16)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

M3K14_MOUSE
NC score	0.016276 (rank : 17)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	889	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

SNIP_HUMAN
NC score	0.013894 (rank : 18)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ZC3H3_MOUSE
NC score	0.013677 (rank : 19)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ASXL1_MOUSE
NC score	0.011758 (rank : 20)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	182	Shared Neighborhood Hits	4
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

M3K14_HUMAN
NC score	0.011424 (rank : 21)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	887	Shared Neighborhood Hits	8
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

AKAP1_HUMAN
NC score	0.011391 (rank : 22)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

RIMS2_HUMAN
NC score	0.010981 (rank : 23)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

NKTR_HUMAN
NC score	0.010695 (rank : 24)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

FOXN1_MOUSE
NC score	0.010445 (rank : 25)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	300	Shared Neighborhood Hits	3
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

HIPK1_MOUSE
NC score	0.009961 (rank : 26)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

SNPC4_HUMAN
NC score	0.009780 (rank : 27)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	589	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

HIPK1_HUMAN
NC score	0.008782 (rank : 28)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

TARA_MOUSE
NC score	0.007919 (rank : 29)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PASK_MOUSE
NC score	0.007399 (rank : 30)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	867	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

VAV3_HUMAN
NC score	0.006755 (rank : 31)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	398	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

DDX24_MOUSE
NC score	0.006405 (rank : 32)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

SALL3_HUMAN
NC score	0.006184 (rank : 33)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	1066	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

MRCKB_MOUSE
NC score	0.005740 (rank : 34)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	2180	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PITX2_HUMAN
NC score	0.005696 (rank : 35)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
NC score	0.005547 (rank : 36)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	383	Shared Neighborhood Hits	3
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

ZFP37_HUMAN
NC score	0.005419 (rank : 37)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).

MRCKB_HUMAN
NC score	0.004814 (rank : 38)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	2239	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).