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Network neighborhood for query Sequence : XRN2_HUMAN

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XRN2_HUMAN
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

XRN2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

XRN2_MOUSE
θ value	0 (rank : 2)	NC score	0.999312 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

XRN1_HUMAN
θ value	3.0147e-88 (rank : 3)	NC score	0.843407 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

XRN1_MOUSE
θ value	2.5521e-87 (rank : 4)	NC score	0.839006 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

ANK2_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.018818 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1615	Shared Neighborhood Hits	4
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RFA1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.044434 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

SIPA1_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.023110 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

NDK7_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.020797 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

SIPA1_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.018509 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

ADDB_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.008647 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	574	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

SGCA_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.017643 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P82350, O35311, O88490	Gene names	Sgca
Domain Architecture
Description	Alpha-sarcoglycan precursor (Alpha-SG) (Adhalin) (50 kDa dystrophin- associated glycoprotein) (50DAG).

ZC3H5_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.013303 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

NFAC2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.015312 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

SGCA_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.016199 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q16586, Q13710, Q13712	Gene names	SGCA, ADL, DAG2
Domain Architecture
Description	Alpha-sarcoglycan precursor (Alpha-SG) (Adhalin) (50 kDa dystrophin- associated glycoprotein) (50DAG) (Dystroglycan 2).

Hits sorted by NC score

XRN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

XRN2_MOUSE
NC score	0.999312 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

XRN1_HUMAN
NC score	0.843407 (rank : 3)	θ value	3.0147e-88 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

XRN1_MOUSE
NC score	0.839006 (rank : 4)	θ value	2.5521e-87 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

RFA1_HUMAN
NC score	0.044434 (rank : 5)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

SIPA1_HUMAN
NC score	0.023110 (rank : 6)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

NDK7_MOUSE
NC score	0.020797 (rank : 7)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

ANK2_HUMAN
NC score	0.018818 (rank : 8)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1615	Shared Neighborhood Hits	4
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SIPA1_MOUSE
NC score	0.018509 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SGCA_MOUSE
NC score	0.017643 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P82350, O35311, O88490	Gene names	Sgca
Domain Architecture
Description	Alpha-sarcoglycan precursor (Alpha-SG) (Adhalin) (50 kDa dystrophin- associated glycoprotein) (50DAG).

SGCA_HUMAN
NC score	0.016199 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q16586, Q13710, Q13712	Gene names	SGCA, ADL, DAG2
Domain Architecture
Description	Alpha-sarcoglycan precursor (Alpha-SG) (Adhalin) (50 kDa dystrophin- associated glycoprotein) (50DAG) (Dystroglycan 2).

NFAC2_MOUSE
NC score	0.015312 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

ZC3H5_HUMAN
NC score	0.013303 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ADDB_MOUSE
NC score	0.008647 (rank : 14)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	574	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).