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Network neighborhood for query Sequence : RFA1_HUMAN

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RFA1_HUMAN
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RFA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

RFA1_MOUSE
θ value	0 (rank : 2)	NC score	0.994212 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEE4, Q3TEJ8	Gene names	Rpa1
Domain Architecture	No domain graphic available
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (p70).

MBIP1_MOUSE
θ value	0.365318 (rank : 3)	NC score	0.072040 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

XRN2_HUMAN
θ value	1.81305 (rank : 4)	NC score	0.044434 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

XRN2_MOUSE
θ value	1.81305 (rank : 5)	NC score	0.044446 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

DTNB_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.017683 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

MCM3A_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.023046 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

NACAM_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.009536 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1866	Shared Neighborhood Hits	4
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SOX13_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.012683 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	495	Shared Neighborhood Hits	3
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

MBIP1_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.050655 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

ZN275_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.000794 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	761	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.

LMAN1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.019470 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

TAU_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.011096 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	502	Shared Neighborhood Hits	3
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

Hits sorted by NC score

RFA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

RFA1_MOUSE
NC score	0.994212 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEE4, Q3TEJ8	Gene names	Rpa1
Domain Architecture	No domain graphic available
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (p70).

MBIP1_MOUSE
NC score	0.072040 (rank : 3)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

MBIP1_HUMAN
NC score	0.050655 (rank : 4)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

XRN2_MOUSE
NC score	0.044446 (rank : 5)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR1, Q3TI26, Q3TKF2, Q3UZT9, Q61489, Q99KS7	Gene names	Xrn2, Dhm1
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (Protein Dhm1).

XRN2_HUMAN
NC score	0.044434 (rank : 6)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0D6, Q3L8N4, Q6KGZ9, Q9BQL1, Q9NTW0, Q9NXS6, Q9UL53	Gene names	XRN2
Domain Architecture
Description	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein).

MCM3A_MOUSE
NC score	0.023046 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

LMAN1_MOUSE
NC score	0.019470 (rank : 8)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

DTNB_MOUSE
NC score	0.017683 (rank : 9)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

SOX13_MOUSE
NC score	0.012683 (rank : 10)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	495	Shared Neighborhood Hits	3
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TAU_MOUSE
NC score	0.011096 (rank : 11)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	502	Shared Neighborhood Hits	3
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NACAM_MOUSE
NC score	0.009536 (rank : 12)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	1866	Shared Neighborhood Hits	4
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ZN275_HUMAN
NC score	0.000794 (rank : 13)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	761	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.