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Network neighborhood for query Sequence : SSDH_HUMAN

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SSDH_HUMAN
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SSDH_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

SSDH_MOUSE
θ value	0 (rank : 2)	NC score	0.998954 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BWF0	Gene names	Aldh5a1
Domain Architecture	No domain graphic available
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

AL1A2_MOUSE
θ value	2.47765e-74 (rank : 3)	NC score	0.964468 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q62148, Q6DI79	Gene names	Aldh1a2, Aldh1a7, Raldh2
Domain Architecture
Description	Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2).

AL1A2_HUMAN
θ value	2.09745e-73 (rank : 4)	NC score	0.964428 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	O94788, Q2PJS6, Q8NHQ4, Q9UBR8, Q9UFY0	Gene names	ALDH1A2, RALDH2
Domain Architecture
Description	Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2).

AL9A1_MOUSE
θ value	1.50314e-71 (rank : 5)	NC score	0.972573 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLJ2	Gene names	Aldh9a1
Domain Architecture	No domain graphic available
Description	4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3).

AL1A1_MOUSE
θ value	2.56397e-71 (rank : 6)	NC score	0.965200 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P24549, Q7TQJ0, Q811J0	Gene names	Aldh1a1, Ahd-2, Ahd2, Aldh1
Domain Architecture
Description	Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1).

AL1A1_HUMAN
θ value	1.07722e-69 (rank : 7)	NC score	0.964020 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P00352, O00768	Gene names	ALDH1A1, ALDC, ALDH1
Domain Architecture
Description	Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1).

FTHFD_MOUSE
θ value	1.07722e-69 (rank : 8)	NC score	0.953844 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R0Y6	Gene names	Aldh1l1, Fthfd
Domain Architecture
Description	10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1).

AL1A3_HUMAN
θ value	1.83746e-69 (rank : 9)	NC score	0.964827 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P47895, Q6NT64	Gene names	ALDH1A3, ALDH6
Domain Architecture
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

AL1A3_MOUSE
θ value	1.00825e-67 (rank : 10)	NC score	0.964884 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHW9, Q9EQP7, Q9JI72	Gene names	Aldh1a3, Aldh6, Raldh3
Domain Architecture	No domain graphic available
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

AL9A1_HUMAN
θ value	1.00825e-67 (rank : 11)	NC score	0.972210 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P49189, Q5VV90, Q6LCL1, Q9NZT7	Gene names	ALDH9A1, ALDH7, ALDH9
Domain Architecture
Description	4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) (Aldehyde dehydrogenase E3 isozyme) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R- aminobutyraldehyde dehydrogenase).

FTHFD_HUMAN
θ value	1.00825e-67 (rank : 12)	NC score	0.954414 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	O75891, Q68CS1	Gene names	ALDH1L1, FTHFD
Domain Architecture
Description	10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1).

ALDH2_HUMAN
θ value	7.98882e-65 (rank : 13)	NC score	0.961879 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P05091, Q03639, Q6IB13, Q6IV71	Gene names	ALDH2, ALDM
Domain Architecture
Description	Aldehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2).

AL1B1_HUMAN
θ value	8.26713e-62 (rank : 14)	NC score	0.962588 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P30837	Gene names	ALDH1B1, ALDH5, ALDHX
Domain Architecture
Description	Aldehyde dehydrogenase X, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2).

ALDH2_MOUSE
θ value	5.35859e-61 (rank : 15)	NC score	0.960460 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P47738	Gene names	Aldh2, Ahd-1, Ahd1
Domain Architecture
Description	Aldehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2) (AHD-M1) (ALDHI) (ALDH-E2).

MMSA_HUMAN
θ value	9.48078e-50 (rank : 16)	NC score	0.965124 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q02252, Q9UKM8	Gene names	ALDH6A1, MMSDH
Domain Architecture
Description	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18).

AL7A1_HUMAN
θ value	1.19932e-44 (rank : 17)	NC score	0.942310 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	P49419, O14619, Q6IPU8, Q9BUL4	Gene names	ALDH7A1, ATQ1
Domain Architecture
Description	Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3) (Antiquitin-1).

AL7A1_MOUSE
θ value	1.12253e-42 (rank : 18)	NC score	0.941671 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBF1	Gene names	Aldh7a1, Ald7a1
Domain Architecture
Description	Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3) (Antiquitin-1).

AL3B1_MOUSE
θ value	1.98606e-31 (rank : 19)	NC score	0.853202 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VQ0, Q63ZW3, Q8VHW0, Q9CW05	Gene names	Aldh3b1, Aldh7
Domain Architecture	No domain graphic available
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

AL3A1_HUMAN
θ value	2.86786e-30 (rank : 20)	NC score	0.869854 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

AL3A1_MOUSE
θ value	2.86786e-30 (rank : 21)	NC score	0.869378 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P47739, Q9R203	Gene names	Aldh3a1, Ahd-4, Ahd4, Aldh3, Aldh4
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (Dioxin-inducible aldehyde dehydrogenase 3).

AL3B1_HUMAN
θ value	3.74554e-30 (rank : 22)	NC score	0.851921 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P43353, Q53XL5, Q8N515, Q96CK8	Gene names	ALDH3B1, ALDH7
Domain Architecture
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

AL3A2_MOUSE
θ value	7.06379e-29 (rank : 23)	NC score	0.864241 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P47740	Gene names	Aldh3a2, Ahd-3, Ahd3, Aldh3, Aldh4
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

AL3B2_HUMAN
θ value	3.87602e-27 (rank : 24)	NC score	0.861906 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

AL3A2_HUMAN
θ value	2.51237e-26 (rank : 25)	NC score	0.853965 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P51648, Q93011, Q96J37	Gene names	ALDH3A2, ALDH10, FALDH
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

AL4A1_HUMAN
θ value	2.06002e-20 (rank : 26)	NC score	0.867277 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P30038, Q16882, Q8IZ38, Q96IF0	Gene names	ALDH4A1, ALDH4, P5CDH
Domain Architecture
Description	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1).

AL4A1_MOUSE
θ value	2.5182e-18 (rank : 27)	NC score	0.857296 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHT0, Q7TND0, Q8BXM3, Q8R0N1, Q8R1S2	Gene names	Aldh4a1
Domain Architecture	No domain graphic available
Description	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1).

3HIDH_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.041448 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

3HIDH_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.034353 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

CO5_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.006378 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

PRRT3_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.009278 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TOP2B_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.006781 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.006822 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

FMT_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.071130 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DP5	Gene names	MTFMT, FMT, FMT1
Domain Architecture
Description	Methionyl-tRNA formyltransferase, mitochondrial precursor (EC 2.1.2.9) (MtFMT).

FMT_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.074107 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D799, Q8VE89	Gene names	Mtfmt, Fmt
Domain Architecture
Description	Methionyl-tRNA formyltransferase, mitochondrial precursor (EC 2.1.2.9) (MtFMT).

Hits sorted by NC score

SSDH_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

SSDH_MOUSE
NC score	0.998954 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BWF0	Gene names	Aldh5a1
Domain Architecture	No domain graphic available
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

AL9A1_MOUSE
NC score	0.972573 (rank : 3)	θ value	1.50314e-71 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLJ2	Gene names	Aldh9a1
Domain Architecture	No domain graphic available
Description	4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3).

AL9A1_HUMAN
NC score	0.972210 (rank : 4)	θ value	1.00825e-67 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P49189, Q5VV90, Q6LCL1, Q9NZT7	Gene names	ALDH9A1, ALDH7, ALDH9
Domain Architecture
Description	4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) (Aldehyde dehydrogenase E3 isozyme) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R- aminobutyraldehyde dehydrogenase).

AL1A1_MOUSE
NC score	0.965200 (rank : 5)	θ value	2.56397e-71 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P24549, Q7TQJ0, Q811J0	Gene names	Aldh1a1, Ahd-2, Ahd2, Aldh1
Domain Architecture
Description	Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1).

MMSA_HUMAN
NC score	0.965124 (rank : 6)	θ value	9.48078e-50 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q02252, Q9UKM8	Gene names	ALDH6A1, MMSDH
Domain Architecture
Description	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18).

AL1A3_MOUSE
NC score	0.964884 (rank : 7)	θ value	1.00825e-67 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHW9, Q9EQP7, Q9JI72	Gene names	Aldh1a3, Aldh6, Raldh3
Domain Architecture	No domain graphic available
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

AL1A3_HUMAN
NC score	0.964827 (rank : 8)	θ value	1.83746e-69 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P47895, Q6NT64	Gene names	ALDH1A3, ALDH6
Domain Architecture
Description	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3).

AL1A2_MOUSE
NC score	0.964468 (rank : 9)	θ value	2.47765e-74 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q62148, Q6DI79	Gene names	Aldh1a2, Aldh1a7, Raldh2
Domain Architecture
Description	Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2).

AL1A2_HUMAN
NC score	0.964428 (rank : 10)	θ value	2.09745e-73 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	O94788, Q2PJS6, Q8NHQ4, Q9UBR8, Q9UFY0	Gene names	ALDH1A2, RALDH2
Domain Architecture
Description	Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2) (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2).

AL1A1_HUMAN
NC score	0.964020 (rank : 11)	θ value	1.07722e-69 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P00352, O00768	Gene names	ALDH1A1, ALDC, ALDH1
Domain Architecture
Description	Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1).

AL1B1_HUMAN
NC score	0.962588 (rank : 12)	θ value	8.26713e-62 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P30837	Gene names	ALDH1B1, ALDH5, ALDHX
Domain Architecture
Description	Aldehyde dehydrogenase X, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2).

ALDH2_HUMAN
NC score	0.961879 (rank : 13)	θ value	7.98882e-65 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P05091, Q03639, Q6IB13, Q6IV71	Gene names	ALDH2, ALDM
Domain Architecture
Description	Aldehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2).

ALDH2_MOUSE
NC score	0.960460 (rank : 14)	θ value	5.35859e-61 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P47738	Gene names	Aldh2, Ahd-1, Ahd1
Domain Architecture
Description	Aldehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2) (AHD-M1) (ALDHI) (ALDH-E2).

FTHFD_HUMAN
NC score	0.954414 (rank : 15)	θ value	1.00825e-67 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	O75891, Q68CS1	Gene names	ALDH1L1, FTHFD
Domain Architecture
Description	10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1).

FTHFD_MOUSE
NC score	0.953844 (rank : 16)	θ value	1.07722e-69 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R0Y6	Gene names	Aldh1l1, Fthfd
Domain Architecture
Description	10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1).

AL7A1_HUMAN
NC score	0.942310 (rank : 17)	θ value	1.19932e-44 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	P49419, O14619, Q6IPU8, Q9BUL4	Gene names	ALDH7A1, ATQ1
Domain Architecture
Description	Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3) (Antiquitin-1).

AL7A1_MOUSE
NC score	0.941671 (rank : 18)	θ value	1.12253e-42 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBF1	Gene names	Aldh7a1, Ald7a1
Domain Architecture
Description	Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3) (Antiquitin-1).

AL3A1_HUMAN
NC score	0.869854 (rank : 19)	θ value	2.86786e-30 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

AL3A1_MOUSE
NC score	0.869378 (rank : 20)	θ value	2.86786e-30 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P47739, Q9R203	Gene names	Aldh3a1, Ahd-4, Ahd4, Aldh3, Aldh4
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (Dioxin-inducible aldehyde dehydrogenase 3).

AL4A1_HUMAN
NC score	0.867277 (rank : 21)	θ value	2.06002e-20 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P30038, Q16882, Q8IZ38, Q96IF0	Gene names	ALDH4A1, ALDH4, P5CDH
Domain Architecture
Description	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1).

AL3A2_MOUSE
NC score	0.864241 (rank : 22)	θ value	7.06379e-29 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P47740	Gene names	Aldh3a2, Ahd-3, Ahd3, Aldh3, Aldh4
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

AL3B2_HUMAN
NC score	0.861906 (rank : 23)	θ value	3.87602e-27 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P48448, Q8NAL5, Q96IB2	Gene names	ALDH3B2, ALDH8
Domain Architecture
Description	Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8).

AL4A1_MOUSE
NC score	0.857296 (rank : 24)	θ value	2.5182e-18 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHT0, Q7TND0, Q8BXM3, Q8R0N1, Q8R1S2	Gene names	Aldh4a1
Domain Architecture	No domain graphic available
Description	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1).

AL3A2_HUMAN
NC score	0.853965 (rank : 25)	θ value	2.51237e-26 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P51648, Q93011, Q96J37	Gene names	ALDH3A2, ALDH10, FALDH
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

AL3B1_MOUSE
NC score	0.853202 (rank : 26)	θ value	1.98606e-31 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VQ0, Q63ZW3, Q8VHW0, Q9CW05	Gene names	Aldh3b1, Aldh7
Domain Architecture	No domain graphic available
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

AL3B1_HUMAN
NC score	0.851921 (rank : 27)	θ value	3.74554e-30 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P43353, Q53XL5, Q8N515, Q96CK8	Gene names	ALDH3B1, ALDH7
Domain Architecture
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

FMT_MOUSE
NC score	0.074107 (rank : 28)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D799, Q8VE89	Gene names	Mtfmt, Fmt
Domain Architecture
Description	Methionyl-tRNA formyltransferase, mitochondrial precursor (EC 2.1.2.9) (MtFMT).

FMT_HUMAN
NC score	0.071130 (rank : 29)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DP5	Gene names	MTFMT, FMT, FMT1
Domain Architecture
Description	Methionyl-tRNA formyltransferase, mitochondrial precursor (EC 2.1.2.9) (MtFMT).

3HIDH_HUMAN
NC score	0.041448 (rank : 30)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

3HIDH_MOUSE
NC score	0.034353 (rank : 31)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

PRRT3_MOUSE
NC score	0.009278 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TOP2B_MOUSE
NC score	0.006822 (rank : 33)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_HUMAN
NC score	0.006781 (rank : 34)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

CO5_HUMAN
NC score	0.006378 (rank : 35)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].