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Network neighborhood for query Sequence : 3HIDH_HUMAN

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3HIDH_HUMAN
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

3HIDH_HUMAN
θ value	1.60882e-182 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

3HIDH_MOUSE
θ value	2.32852e-173 (rank : 2)	NC score	0.997794 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

6PGD_MOUSE
θ value	0.00228821 (rank : 3)	NC score	0.234082 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD0, Q3UD80	Gene names	Pgd
Domain Architecture
Description	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).

6PGD_HUMAN
θ value	0.00665767 (rank : 4)	NC score	0.226790 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P52209, Q9BWD8	Gene names	PGD, PGDH
Domain Architecture
Description	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).

SSDH_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.041448 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

SSDH_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.039544 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWF0	Gene names	Aldh5a1
Domain Architecture	No domain graphic available
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

LIGA_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.032272 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

CTBP1_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.035672 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

ECHP_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.017608 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBM2	Gene names	Ehhadh
Domain Architecture
Description	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)].

CTBP1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.034423 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

ZNFX1_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.012221 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	407	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CTBP2_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.033044 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.032979 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

DDFL1_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.007013 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GTR10_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.013586 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O95528, Q9H4I6	Gene names	SLC2A10, GLUT10
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 10 (Glucose transporter type 10).

Hits sorted by NC score

3HIDH_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.60882e-182 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P31937, Q9UDN3	Gene names	HIBADH
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

3HIDH_MOUSE
NC score	0.997794 (rank : 2)	θ value	2.32852e-173 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L13, Q8BJY2	Gene names	Hibadh
Domain Architecture
Description	3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor (EC 1.1.1.31) (HIBADH).

6PGD_MOUSE
NC score	0.234082 (rank : 3)	θ value	0.00228821 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCD0, Q3UD80	Gene names	Pgd
Domain Architecture
Description	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).

6PGD_HUMAN
NC score	0.226790 (rank : 4)	θ value	0.00665767 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P52209, Q9BWD8	Gene names	PGD, PGDH
Domain Architecture
Description	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).

SSDH_HUMAN
NC score	0.041448 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

SSDH_MOUSE
NC score	0.039544 (rank : 6)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWF0	Gene names	Aldh5a1
Domain Architecture	No domain graphic available
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

CTBP1_HUMAN
NC score	0.035672 (rank : 7)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q13363	Gene names	CTBP1, CTBP
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP1_MOUSE
NC score	0.034423 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O88712, Q9QYG2	Gene names	Ctbp1
Domain Architecture
Description	C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1).

CTBP2_HUMAN
NC score	0.033044 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P56545, O43449	Gene names	CTBP2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

CTBP2_MOUSE
NC score	0.032979 (rank : 10)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P56546, O54855, O88462	Gene names	Ctbp2
Domain Architecture
Description	C-terminal-binding protein 2 (CtBP2).

LIGA_HUMAN
NC score	0.032272 (rank : 11)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

ECHP_MOUSE
NC score	0.017608 (rank : 12)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBM2	Gene names	Ehhadh
Domain Architecture
Description	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)].

GTR10_HUMAN
NC score	0.013586 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O95528, Q9H4I6	Gene names	SLC2A10, GLUT10
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 10 (Glucose transporter type 10).

ZNFX1_MOUSE
NC score	0.012221 (rank : 14)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	407	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

DDFL1_MOUSE
NC score	0.007013 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.