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Network neighborhood for query Sequence : MBP_HUMAN

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MBP_HUMAN
SwissProt Accessions	P02686, Q15337, Q15338, Q15339, Q15340, Q6AI64, Q6FH37, Q6FI04, Q6PK23	Gene names	MBP
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MBP_HUMAN
θ value	8.26266e-179 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P02686, Q15337, Q15338, Q15339, Q15340, Q6AI64, Q6FH37, Q6FI04, Q6PK23	Gene names	MBP
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein).

MBP_MOUSE
θ value	2.89301e-115 (rank : 2)	NC score	0.978130 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P04370, Q01585, Q03139, Q03176, Q61836, Q61837, Q99KE4, Q9QWP1	Gene names	Mbp, Shi
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein).

FILA_HUMAN
θ value	6.43352e-06 (rank : 3)	NC score	0.176514 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	685	Shared Neighborhood Hits	20
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

BCAS1_MOUSE
θ value	0.00869519 (rank : 4)	NC score	0.118651 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	215	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

DSPP_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.110196 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RSF1_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.048483 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	539	Shared Neighborhood Hits	6
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

ZN219_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.016301 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	876	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

PP2CG_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.058083 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PP2CG_MOUSE
θ value	0.813845 (rank : 9)	NC score	0.061513 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

MAP9_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.042702 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	518	Shared Neighborhood Hits	7
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

TNR6A_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.073700 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	343	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

AP3B1_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.037113 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	283	Shared Neighborhood Hits	11
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

HORN_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.096556 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

SFRS4_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.037081 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

DSPP_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.085231 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HNRPR_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.020468 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	O43390	Gene names	HNRPR
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein R (hnRNP R).

RPTN_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.060127 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	650	Shared Neighborhood Hits	14
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CD2L1_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.005855 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	1467	Shared Neighborhood Hits	9
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CENPF_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.006859 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	1932	Shared Neighborhood Hits	10
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ILF3_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.027594 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

RNPS1_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.037690 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.037690 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

ARHG7_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.009905 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

CD2L1_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.004581 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	1463	Shared Neighborhood Hits	8
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

GDIB_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.014518 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

MUC13_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.018763 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	447	Shared Neighborhood Hits	4
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SRGP2_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.009501 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TOP2B_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.015670 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

AHI1_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.008619 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	537	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

DZIP3_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.012666 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

NPAS3_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.009852 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

TARA_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.028704 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	1626	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TTC14_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.025964 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

BCAS1_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.054146 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

HORN_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.066477 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

RPTN_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.052003 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

Hits sorted by NC score

MBP_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.26266e-179 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P02686, Q15337, Q15338, Q15339, Q15340, Q6AI64, Q6FH37, Q6FI04, Q6PK23	Gene names	MBP
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein).

MBP_MOUSE
NC score	0.978130 (rank : 2)	θ value	2.89301e-115 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P04370, Q01585, Q03139, Q03176, Q61836, Q61837, Q99KE4, Q9QWP1	Gene names	Mbp, Shi
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein).

FILA_HUMAN
NC score	0.176514 (rank : 3)	θ value	6.43352e-06 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	685	Shared Neighborhood Hits	20
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

BCAS1_MOUSE
NC score	0.118651 (rank : 4)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	215	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

DSPP_HUMAN
NC score	0.110196 (rank : 5)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HORN_HUMAN
NC score	0.096556 (rank : 6)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

DSPP_MOUSE
NC score	0.085231 (rank : 7)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TNR6A_HUMAN
NC score	0.073700 (rank : 8)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	343	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

HORN_MOUSE
NC score	0.066477 (rank : 9)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PP2CG_MOUSE
NC score	0.061513 (rank : 10)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

RPTN_MOUSE
NC score	0.060127 (rank : 11)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	650	Shared Neighborhood Hits	14
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

PP2CG_HUMAN
NC score	0.058083 (rank : 12)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

BCAS1_HUMAN
NC score	0.054146 (rank : 13)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

RPTN_HUMAN
NC score	0.052003 (rank : 14)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RSF1_HUMAN
NC score	0.048483 (rank : 15)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	539	Shared Neighborhood Hits	6
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MAP9_HUMAN
NC score	0.042702 (rank : 16)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	518	Shared Neighborhood Hits	7
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RNPS1_HUMAN
NC score	0.037690 (rank : 17)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.037690 (rank : 18)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

AP3B1_HUMAN
NC score	0.037113 (rank : 19)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	283	Shared Neighborhood Hits	11
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

SFRS4_MOUSE
NC score	0.037081 (rank : 20)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TARA_HUMAN
NC score	0.028704 (rank : 21)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	1626	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ILF3_HUMAN
NC score	0.027594 (rank : 22)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

TTC14_HUMAN
NC score	0.025964 (rank : 23)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

HNRPR_HUMAN
NC score	0.020468 (rank : 24)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	O43390	Gene names	HNRPR
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein R (hnRNP R).

MUC13_MOUSE
NC score	0.018763 (rank : 25)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	447	Shared Neighborhood Hits	4
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ZN219_HUMAN
NC score	0.016301 (rank : 26)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	876	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

TOP2B_HUMAN
NC score	0.015670 (rank : 27)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

GDIB_HUMAN
NC score	0.014518 (rank : 28)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

DZIP3_MOUSE
NC score	0.012666 (rank : 29)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ARHG7_HUMAN
NC score	0.009905 (rank : 30)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

NPAS3_MOUSE
NC score	0.009852 (rank : 31)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

SRGP2_MOUSE
NC score	0.009501 (rank : 32)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

AHI1_HUMAN
NC score	0.008619 (rank : 33)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	537	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CENPF_HUMAN
NC score	0.006859 (rank : 34)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	1932	Shared Neighborhood Hits	10
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CD2L1_HUMAN
NC score	0.005855 (rank : 35)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	1467	Shared Neighborhood Hits	9
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
NC score	0.004581 (rank : 36)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	1463	Shared Neighborhood Hits	8
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).