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Network neighborhood for query Sequence : MBD2_HUMAN

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MBD2_HUMAN
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MBD2_HUMAN
θ value	2.67656e-153 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD2_MOUSE
θ value	1.46868e-151 (rank : 2)	NC score	0.995763 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MBD3_HUMAN
θ value	3.31004e-111 (rank : 3)	NC score	0.986145 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_MOUSE
θ value	1.64275e-110 (rank : 4)	NC score	0.985775 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MB3L1_HUMAN
θ value	3.3877e-31 (rank : 5)	NC score	0.832795 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L1_MOUSE
θ value	2.27762e-19 (rank : 6)	NC score	0.784013 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MBD1_MOUSE
θ value	3.63628e-17 (rank : 7)	NC score	0.539285 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
θ value	1.38178e-16 (rank : 8)	NC score	0.532367 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MB3L2_HUMAN
θ value	7.58209e-15 (rank : 9)	NC score	0.720573 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

MECP2_HUMAN
θ value	1.133e-10 (rank : 10)	NC score	0.508760 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
θ value	1.47974e-10 (rank : 11)	NC score	0.502581 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MBD4_MOUSE
θ value	6.43352e-06 (rank : 12)	NC score	0.376482 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

MBD4_HUMAN
θ value	1.87187e-05 (rank : 13)	NC score	0.368141 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

RRBP1_MOUSE
θ value	3.19293e-05 (rank : 14)	NC score	0.042308 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CO7A1_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.018894 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	807	Shared Neighborhood Hits	11
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

BAZ2B_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.086071 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.074969 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.074892 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	744	Shared Neighborhood Hits	14
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

HCN2_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.024420 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

PGCA_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.021412 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	643	Shared Neighborhood Hits	8
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MORC2_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.023443 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

ZN148_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.005945 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	747	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

MY18A_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.012054 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	1929	Shared Neighborhood Hits	17
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NR2E3_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.005913 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

THIKA_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.018272 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q921H8	Gene names	Acaa1a, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase A, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase A) (Acetyl-CoA acyltransferase A) (Peroxisomal 3-oxoacyl- CoA thiolase A).

CO9A1_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.012736 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

NSMA2_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.023255 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

OPA1_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.028657 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

YLPM1_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.019114 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	670	Shared Neighborhood Hits	7
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZN148_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.004583 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

A20A1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.015124 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	698	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.015470 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	716	Shared Neighborhood Hits	9
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.014930 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.015059 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	710	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

CN104_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.033938 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

HEM6_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.016984 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P36551, Q14060, Q8IZ45, Q96AF3	Gene names	CPOX, CPO, CPX
Domain Architecture
Description	Coproporphyrinogen III oxidase, mitochondrial precursor (EC 1.3.3.3) (Coproporphyrinogenase) (Coprogen oxidase) (COX).

MY18B_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.015721 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	1299	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MELPH_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.016596 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MORN1_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.011999 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

PDCD7_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.013976 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PODO_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.009619 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

P80C_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.023327 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

SPEG_HUMAN
θ value	8.99809 (rank : 43)	NC score	-0.001371 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	1762	Shared Neighborhood Hits	11
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SURF6_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.015236 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

TNK1_HUMAN
θ value	8.99809 (rank : 45)	NC score	-0.001207 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	815	Shared Neighborhood Hits	3
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TOP2B_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.007868 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

CXCC1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.051168 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.051343 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

Hits sorted by NC score

MBD2_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.67656e-153 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD2_MOUSE
NC score	0.995763 (rank : 2)	θ value	1.46868e-151 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MBD3_HUMAN
NC score	0.986145 (rank : 3)	θ value	3.31004e-111 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_MOUSE
NC score	0.985775 (rank : 4)	θ value	1.64275e-110 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MB3L1_HUMAN
NC score	0.832795 (rank : 5)	θ value	3.3877e-31 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L1_MOUSE
NC score	0.784013 (rank : 6)	θ value	2.27762e-19 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L2_HUMAN
NC score	0.720573 (rank : 7)	θ value	7.58209e-15 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

MBD1_MOUSE
NC score	0.539285 (rank : 8)	θ value	3.63628e-17 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
NC score	0.532367 (rank : 9)	θ value	1.38178e-16 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MECP2_HUMAN
NC score	0.508760 (rank : 10)	θ value	1.133e-10 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
NC score	0.502581 (rank : 11)	θ value	1.47974e-10 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MBD4_MOUSE
NC score	0.376482 (rank : 12)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

MBD4_HUMAN
NC score	0.368141 (rank : 13)	θ value	1.87187e-05 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

BAZ2B_HUMAN
NC score	0.086071 (rank : 14)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_HUMAN
NC score	0.074969 (rank : 15)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.074892 (rank : 16)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	744	Shared Neighborhood Hits	14
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CXCC1_MOUSE
NC score	0.051343 (rank : 17)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_HUMAN
NC score	0.051168 (rank : 18)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

RRBP1_MOUSE
NC score	0.042308 (rank : 19)	θ value	3.19293e-05 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CN104_MOUSE
NC score	0.033938 (rank : 20)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

OPA1_HUMAN
NC score	0.028657 (rank : 21)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

HCN2_HUMAN
NC score	0.024420 (rank : 22)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MORC2_HUMAN
NC score	0.023443 (rank : 23)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

P80C_HUMAN
NC score	0.023327 (rank : 24)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

NSMA2_MOUSE
NC score	0.023255 (rank : 25)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PGCA_MOUSE
NC score	0.021412 (rank : 26)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	643	Shared Neighborhood Hits	8
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

YLPM1_HUMAN
NC score	0.019114 (rank : 27)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	670	Shared Neighborhood Hits	7
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CO7A1_HUMAN
NC score	0.018894 (rank : 28)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	807	Shared Neighborhood Hits	11
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

THIKA_MOUSE
NC score	0.018272 (rank : 29)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q921H8	Gene names	Acaa1a, Acaa1
Domain Architecture	No domain graphic available
Description	3-ketoacyl-CoA thiolase A, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase A) (Acetyl-CoA acyltransferase A) (Peroxisomal 3-oxoacyl- CoA thiolase A).

HEM6_HUMAN
NC score	0.016984 (rank : 30)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P36551, Q14060, Q8IZ45, Q96AF3	Gene names	CPOX, CPO, CPX
Domain Architecture
Description	Coproporphyrinogen III oxidase, mitochondrial precursor (EC 1.3.3.3) (Coproporphyrinogenase) (Coprogen oxidase) (COX).

MELPH_MOUSE
NC score	0.016596 (rank : 31)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MY18B_HUMAN
NC score	0.015721 (rank : 32)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	1299	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

A20A2_HUMAN
NC score	0.015470 (rank : 33)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	716	Shared Neighborhood Hits	9
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

SURF6_MOUSE
NC score	0.015236 (rank : 34)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

A20A1_HUMAN
NC score	0.015124 (rank : 35)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	698	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.015059 (rank : 36)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	710	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

A20A3_HUMAN
NC score	0.014930 (rank : 37)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

PDCD7_HUMAN
NC score	0.013976 (rank : 38)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

CO9A1_HUMAN
NC score	0.012736 (rank : 39)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

MY18A_HUMAN
NC score	0.012054 (rank : 40)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	1929	Shared Neighborhood Hits	17
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MORN1_HUMAN
NC score	0.011999 (rank : 41)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

PODO_HUMAN
NC score	0.009619 (rank : 42)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

TOP2B_HUMAN
NC score	0.007868 (rank : 43)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

ZN148_HUMAN
NC score	0.005945 (rank : 44)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	747	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

NR2E3_MOUSE
NC score	0.005913 (rank : 45)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

ZN148_MOUSE
NC score	0.004583 (rank : 46)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

TNK1_HUMAN
NC score	-0.001207 (rank : 47)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	815	Shared Neighborhood Hits	3
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

SPEG_HUMAN
NC score	-0.001371 (rank : 48)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	1762	Shared Neighborhood Hits	11
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).