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Network neighborhood for query Sequence : K1267_HUMAN

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K1267_HUMAN
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K1267_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

K1267_MOUSE
θ value	0 (rank : 2)	NC score	0.988113 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

ZN282_HUMAN
θ value	0.0431538 (rank : 3)	NC score	0.012376 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	796	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

IWS1_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.039076 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	1241	Shared Neighborhood Hits	23
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NFAT5_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.040383 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

RGS3_MOUSE
θ value	0.163984 (rank : 6)	NC score	0.037215 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	1621	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MDC1_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.045853 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CP135_MOUSE
θ value	0.47712 (rank : 8)	NC score	0.017840 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	1278	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TXLNG_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.045647 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	568	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

TXLNG_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.043892 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

MRCKB_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.012222 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	2239	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SCYBG_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.058507 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

TARA_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.034851 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	1133	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LCP2_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.046757 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SPTB1_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.014545 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	541	Shared Neighborhood Hits	9
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SLC2B_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.045862 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

ATBF1_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.015499 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	27
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DAF1_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.026337 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MLL2_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.027620 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	1788	Shared Neighborhood Hits	34
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PER3_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.027368 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	479	Shared Neighborhood Hits	18
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

FA5_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.018912 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

ILDR1_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.029989 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

PCLO_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.026340 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	2275	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SRRM2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.053197 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	1296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TGON2_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.039220 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	1037	Shared Neighborhood Hits	29
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AKAP6_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.029625 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

C163B_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.016294 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

CUTL1_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.021409 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GOGA2_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.017727 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LAD1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.034906 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LR37A_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.025037 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	720	Shared Neighborhood Hits	23
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LRP1B_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.009462 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SOX6_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.015097 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SRRM1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.042165 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TXLNB_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.038984 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	912	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

UBAP1_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.044310 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH48, Q8BQ80, Q8BSW6, Q9D749, Q9ERV5	Gene names	Ubap1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP) (Ubiquitin-associated protein NAG20).

ADA12_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.008971 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ERCC5_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.024357 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

CMGA_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.026667 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

GIT2_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.016316 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GRB7_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.018459 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

SRRM1_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.046194 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	966	Shared Neighborhood Hits	27
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.037079 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYNPO_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.027705 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

4ET_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.026488 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

A4_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.016156 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.016092 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AKA12_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.022545 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	19
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ANR11_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.019877 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ARHGC_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.010061 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CN037_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.018693 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

DTNB_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.012901 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

FOG2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.013981 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	731	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

HTF4_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.018019 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

PHF2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.016416 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.020109 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PPIL2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.009596 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

PRR12_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.032422 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	460	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SSFA2_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.036751 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

ABCF3_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.014047 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ATS8_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.004468 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

EXO1_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.015789 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

I10R2_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.013291 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

K1543_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.021389 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KCMA1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.010536 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

MAST2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.003087 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYCD_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.012150 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

UBP53_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.012979 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

ZEP1_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.010381 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

Hits sorted by NC score

K1267_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

K1267_MOUSE
NC score	0.988113 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

SCYBG_MOUSE
NC score	0.058507 (rank : 3)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

SRRM2_HUMAN
NC score	0.053197 (rank : 4)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	1296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

LCP2_MOUSE
NC score	0.046757 (rank : 5)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SRRM1_MOUSE
NC score	0.046194 (rank : 6)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	966	Shared Neighborhood Hits	27
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SLC2B_HUMAN
NC score	0.045862 (rank : 7)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	214	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

MDC1_MOUSE
NC score	0.045853 (rank : 8)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

TXLNG_HUMAN
NC score	0.045647 (rank : 9)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	568	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

UBAP1_MOUSE
NC score	0.044310 (rank : 10)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH48, Q8BQ80, Q8BSW6, Q9D749, Q9ERV5	Gene names	Ubap1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP) (Ubiquitin-associated protein NAG20).

TXLNG_MOUSE
NC score	0.043892 (rank : 11)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

SRRM1_HUMAN
NC score	0.042165 (rank : 12)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

NFAT5_HUMAN
NC score	0.040383 (rank : 13)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

TGON2_HUMAN
NC score	0.039220 (rank : 14)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	1037	Shared Neighborhood Hits	29
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

IWS1_HUMAN
NC score	0.039076 (rank : 15)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	1241	Shared Neighborhood Hits	23
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TXLNB_HUMAN
NC score	0.038984 (rank : 16)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	912	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

RGS3_MOUSE
NC score	0.037215 (rank : 17)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	1621	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SRRM2_MOUSE
NC score	0.037079 (rank : 18)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSFA2_HUMAN
NC score	0.036751 (rank : 19)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

LAD1_HUMAN
NC score	0.034906 (rank : 20)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

TARA_MOUSE
NC score	0.034851 (rank : 21)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	1133	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PRR12_HUMAN
NC score	0.032422 (rank : 22)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	460	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ILDR1_MOUSE
NC score	0.029989 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

AKAP6_HUMAN
NC score	0.029625 (rank : 24)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

SYNPO_HUMAN
NC score	0.027705 (rank : 25)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

MLL2_HUMAN
NC score	0.027620 (rank : 26)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	1788	Shared Neighborhood Hits	34
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PER3_HUMAN
NC score	0.027368 (rank : 27)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	479	Shared Neighborhood Hits	18
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CMGA_HUMAN
NC score	0.026667 (rank : 28)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

4ET_HUMAN
NC score	0.026488 (rank : 29)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

PCLO_MOUSE
NC score	0.026340 (rank : 30)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	2275	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DAF1_MOUSE
NC score	0.026337 (rank : 31)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

LR37A_HUMAN
NC score	0.025037 (rank : 32)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	720	Shared Neighborhood Hits	23
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ERCC5_MOUSE
NC score	0.024357 (rank : 33)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

AKA12_HUMAN
NC score	0.022545 (rank : 34)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	19
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CUTL1_MOUSE
NC score	0.021409 (rank : 35)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

K1543_MOUSE
NC score	0.021389 (rank : 36)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	497	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PHF2_MOUSE
NC score	0.020109 (rank : 37)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ANR11_HUMAN
NC score	0.019877 (rank : 38)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

FA5_HUMAN
NC score	0.018912 (rank : 39)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

CN037_MOUSE
NC score	0.018693 (rank : 40)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

GRB7_MOUSE
NC score	0.018459 (rank : 41)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

HTF4_MOUSE
NC score	0.018019 (rank : 42)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

CP135_MOUSE
NC score	0.017840 (rank : 43)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	1278	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA2_HUMAN
NC score	0.017727 (rank : 44)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

PHF2_HUMAN
NC score	0.016416 (rank : 45)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

GIT2_HUMAN
NC score	0.016316 (rank : 46)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

C163B_HUMAN
NC score	0.016294 (rank : 47)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

A4_HUMAN
NC score	0.016156 (rank : 48)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
NC score	0.016092 (rank : 49)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

EXO1_MOUSE
NC score	0.015789 (rank : 50)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

ATBF1_MOUSE
NC score	0.015499 (rank : 51)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	27
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SOX6_MOUSE
NC score	0.015097 (rank : 52)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SPTB1_HUMAN
NC score	0.014545 (rank : 53)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	541	Shared Neighborhood Hits	9
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

ABCF3_MOUSE
NC score	0.014047 (rank : 54)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

FOG2_HUMAN
NC score	0.013981 (rank : 55)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	731	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

I10R2_MOUSE
NC score	0.013291 (rank : 56)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

UBP53_MOUSE
NC score	0.012979 (rank : 57)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

DTNB_HUMAN
NC score	0.012901 (rank : 58)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	O60941, O43782, O60881, O75538, Q9UE14, Q9UE15, Q9UE16	Gene names	DTNB
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B).

ZN282_HUMAN
NC score	0.012376 (rank : 59)	θ value	0.0431538 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	796	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

MRCKB_HUMAN
NC score	0.012222 (rank : 60)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	2239	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYCD_MOUSE
NC score	0.012150 (rank : 61)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

KCMA1_HUMAN
NC score	0.010536 (rank : 62)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

ZEP1_HUMAN
NC score	0.010381 (rank : 63)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ARHGC_MOUSE
NC score	0.010061 (rank : 64)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PPIL2_MOUSE
NC score	0.009596 (rank : 65)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

LRP1B_HUMAN
NC score	0.009462 (rank : 66)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ADA12_MOUSE
NC score	0.008971 (rank : 67)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ATS8_HUMAN
NC score	0.004468 (rank : 68)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

MAST2_HUMAN
NC score	0.003087 (rank : 69)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).