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Network neighborhood for query Sequence : FRG1_HUMAN

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FRG1_HUMAN
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FRG1_MOUSE
θ value	4.9119e-131 (rank : 1)	NC score	0.998740 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRG1_HUMAN
θ value	2.36115e-125 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRGL_HUMAN
θ value	4.21644e-82 (rank : 3)	NC score	0.990934 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZ01	Gene names	C20orf80
Domain Architecture
Description	Putative FRG1-like protein C20orf80.

FSCN3_MOUSE
θ value	0.0193708 (rank : 4)	NC score	0.148497 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXW4	Gene names	Fscn3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN3_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.119415 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQT6	Gene names	FSCN3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.092393 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

MAP1B_MOUSE
θ value	4.03905 (rank : 7)	NC score	0.019231 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	977	Shared Neighborhood Hits	5
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

OPTN_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.015482 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	1120	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CELR2_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.005804 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	657	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

FSCN1_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.078623 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

MYO7A_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.010243 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.010265 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CELR2_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.005830 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	584	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FBX34_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.015830 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

CAC1C_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.007574 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CN130_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.020847 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

NARG1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.022574 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.022634 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

FSCN2_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.063490 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O14926	Gene names	FSCN2
Domain Architecture
Description	Fascin-2 (Retinal fascin).

Hits sorted by NC score

FRG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.36115e-125 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRG1_MOUSE
NC score	0.998740 (rank : 2)	θ value	4.9119e-131 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRGL_HUMAN
NC score	0.990934 (rank : 3)	θ value	4.21644e-82 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZ01	Gene names	C20orf80
Domain Architecture
Description	Putative FRG1-like protein C20orf80.

FSCN3_MOUSE
NC score	0.148497 (rank : 4)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXW4	Gene names	Fscn3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN3_HUMAN
NC score	0.119415 (rank : 5)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQT6	Gene names	FSCN3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN1_HUMAN
NC score	0.092393 (rank : 6)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

FSCN1_MOUSE
NC score	0.078623 (rank : 7)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

FSCN2_HUMAN
NC score	0.063490 (rank : 8)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O14926	Gene names	FSCN2
Domain Architecture
Description	Fascin-2 (Retinal fascin).

NARG1_MOUSE
NC score	0.022634 (rank : 9)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NARG1_HUMAN
NC score	0.022574 (rank : 10)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

CN130_HUMAN
NC score	0.020847 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

MAP1B_MOUSE
NC score	0.019231 (rank : 12)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	977	Shared Neighborhood Hits	5
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

FBX34_HUMAN
NC score	0.015830 (rank : 13)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

OPTN_MOUSE
NC score	0.015482 (rank : 14)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	1120	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

MYO7A_MOUSE
NC score	0.010265 (rank : 15)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.010243 (rank : 16)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CAC1C_HUMAN
NC score	0.007574 (rank : 17)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CELR2_MOUSE
NC score	0.005830 (rank : 18)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	584	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR2_HUMAN
NC score	0.005804 (rank : 19)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	657	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).