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Network neighborhood for query Sequence : FSCN1_HUMAN

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FSCN1_HUMAN
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FSCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

FSCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999485 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

FSCN2_HUMAN
θ value	7.76955e-161 (rank : 3)	NC score	0.982703 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O14926	Gene names	FSCN2
Domain Architecture
Description	Fascin-2 (Retinal fascin).

FSCN3_MOUSE
θ value	1.72781e-51 (rank : 4)	NC score	0.848054 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXW4	Gene names	Fscn3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN3_HUMAN
θ value	1.85029e-45 (rank : 5)	NC score	0.836844 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQT6	Gene names	FSCN3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FRG1_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.109594 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

CAC1C_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.015424 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

FRG1_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.092393 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

LYST_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.023331 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

LYST_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.021706 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

JIP4_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.007926 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	593	Shared Neighborhood Hits	3
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

FRGL_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.043739 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ01	Gene names	C20orf80
Domain Architecture
Description	Putative FRG1-like protein C20orf80.

GNL3_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.010729 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

S100Z_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.007827 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXG8	Gene names	S100Z
Domain Architecture
Description	Protein S100-Z (S100 calcium-binding protein Z).

Hits sorted by NC score

FSCN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

FSCN1_MOUSE
NC score	0.999485 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

FSCN2_HUMAN
NC score	0.982703 (rank : 3)	θ value	7.76955e-161 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O14926	Gene names	FSCN2
Domain Architecture
Description	Fascin-2 (Retinal fascin).

FSCN3_MOUSE
NC score	0.848054 (rank : 4)	θ value	1.72781e-51 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXW4	Gene names	Fscn3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FSCN3_HUMAN
NC score	0.836844 (rank : 5)	θ value	1.85029e-45 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQT6	Gene names	FSCN3
Domain Architecture
Description	Fascin-3 (Testis fascin).

FRG1_MOUSE
NC score	0.109594 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRG1_HUMAN
NC score	0.092393 (rank : 7)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRGL_HUMAN
NC score	0.043739 (rank : 8)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ01	Gene names	C20orf80
Domain Architecture
Description	Putative FRG1-like protein C20orf80.

LYST_MOUSE
NC score	0.023331 (rank : 9)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

LYST_HUMAN
NC score	0.021706 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

CAC1C_HUMAN
NC score	0.015424 (rank : 11)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

GNL3_HUMAN
NC score	0.010729 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

JIP4_MOUSE
NC score	0.007926 (rank : 13)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	593	Shared Neighborhood Hits	3
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

S100Z_HUMAN
NC score	0.007827 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXG8	Gene names	S100Z
Domain Architecture
Description	Protein S100-Z (S100 calcium-binding protein Z).