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Network neighborhood for query Sequence : S100Z_HUMAN

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S100Z_HUMAN
SwissProt Accessions	Q8WXG8	Gene names	S100Z
Domain Architecture
Description	Protein S100-Z (S100 calcium-binding protein Z).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

S100Z_HUMAN
θ value	1.23823e-49 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXG8	Gene names	S100Z
Domain Architecture
Description	Protein S100-Z (S100 calcium-binding protein Z).

S10A1_HUMAN
θ value	1.16704e-23 (rank : 2)	NC score	0.953230 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	52
SwissProt Accessions	P23297	Gene names	S100A1, S100A
Domain Architecture
Description	Protein S100-A1 (S100 calcium-binding protein A1) (S-100 protein alpha subunit) (S-100 protein alpha chain).

S10A1_MOUSE
θ value	5.79196e-23 (rank : 3)	NC score	0.972094 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P56565, O88949	Gene names	S100a1
Domain Architecture
Description	Protein S100-A1 (S100 calcium-binding protein A1) (S-100 protein alpha subunit) (S-100 protein alpha chain).

S10AA_MOUSE
θ value	7.82807e-20 (rank : 4)	NC score	0.931350 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	P08207	Gene names	S100a10, Cal1l
Domain Architecture
Description	Protein S100-A10 (S100 calcium-binding protein A10) (Calpactin-1 light chain) (Calpactin I light chain) (p10 protein) (p11) (Cellular ligand of annexin II).

S100P_HUMAN
θ value	2.97466e-19 (rank : 5)	NC score	0.965829 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	58	Shared Neighborhood Hits	51
SwissProt Accessions	P25815	Gene names	S100P, S100E
Domain Architecture
Description	Protein S100-P (S100 calcium-binding protein P).

S10AA_HUMAN
θ value	1.47631e-18 (rank : 6)	NC score	0.930003 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	P60903, P08206	Gene names	S100A10, ANX2LG, CAL1L, CLP11
Domain Architecture
Description	Protein S100-A10 (S100 calcium-binding protein A10) (Calpactin-1 light chain) (Calpactin I light chain) (p10 protein) (p11) (Cellular ligand of annexin II).

S10A4_HUMAN
θ value	7.32683e-18 (rank : 7)	NC score	0.942983 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P26447	Gene names	S100A4, CAPL, MTS1
Domain Architecture
Description	Protein S100-A4 (S100 calcium-binding protein A4) (Metastasin) (Protein Mts1) (Placental calcium-binding protein) (Calvasculin).

S10A4_MOUSE
θ value	3.63628e-17 (rank : 8)	NC score	0.921268 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	P07091, P20066	Gene names	S100a4, Capl, Mts1
Domain Architecture
Description	Protein S100-A4 (S100 calcium-binding protein A4) (Metastasin) (Protein Mts1) (Metastatic cell protein) (Placental calcium-binding protein) (18A2) (PEL98).

S100B_MOUSE
θ value	1.058e-16 (rank : 9)	NC score	0.943560 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	P50114	Gene names	S100b
Domain Architecture
Description	Protein S100-B (S100 calcium-binding protein B) (S-100 protein beta subunit) (S-100 protein beta chain).

S100B_HUMAN
θ value	1.38178e-16 (rank : 10)	NC score	0.944547 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	P04271	Gene names	S100B
Domain Architecture
Description	Protein S100-B (S100 calcium-binding protein B) (S-100 protein beta subunit) (S-100 protein beta chain).

S10A2_HUMAN
θ value	2.60593e-15 (rank : 11)	NC score	0.943211 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	P29034, O00266, Q9BU83	Gene names	S100A2, S100L
Domain Architecture
Description	Protein S100-A2 (S100 calcium-binding protein A2) (Protein S-100L) (CAN19).

S10AB_MOUSE
θ value	8.38298e-14 (rank : 12)	NC score	0.917954 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	P50543, Q545S1	Gene names	S100a11, S100c
Domain Architecture
Description	Protein S100-A11 (S100 calcium-binding protein A11) (Protein S100C) (Calgizzarin) (Endothelial monocyte-activating polypeptide) (EMAP).

S10A5_MOUSE
θ value	2.43908e-13 (rank : 13)	NC score	0.924857 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	P63084, O88945, P82540	Gene names	S100a5, S100d
Domain Architecture	No domain graphic available
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).

S10A5_HUMAN
θ value	3.18553e-13 (rank : 14)	NC score	0.894252 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	P33763	Gene names	S100A5, S100D
Domain Architecture
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).

S10AB_HUMAN
θ value	5.43371e-13 (rank : 15)	NC score	0.908995 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	P31949, Q5VTK0	Gene names	S100A11, MLN70, S100C
Domain Architecture
Description	Protein S100-A11 (S100 calcium-binding protein A11) (Protein S100C) (Calgizzarin) (MLN 70).

S10AC_HUMAN
θ value	1.02475e-11 (rank : 16)	NC score	0.922352 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	P80511, P83219	Gene names	S100A12
Domain Architecture
Description	Protein S100-A12 (S100 calcium-binding protein A12) (Calgranulin-C) (CAGC) (CGRP) (Neutrophil S100 protein) (Calcium-binding protein in amniotic fluid 1) (CAAF1) (p6) [Contains: Calcitermin].

S10A6_MOUSE
θ value	2.28291e-11 (rank : 17)	NC score	0.868728 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	P14069	Gene names	S100a6, Cacy
Domain Architecture
Description	Protein S100-A6 (S100 calcium-binding protein A6) (Calcyclin) (Prolactin receptor-associated protein) (5B10).

S10A6_HUMAN
θ value	2.98157e-11 (rank : 18)	NC score	0.872226 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P06703	Gene names	S100A6, CACY
Domain Architecture
Description	Protein S100-A6 (S100 calcium-binding protein A6) (Calcyclin) (Prolactin receptor-associated protein) (PRA) (Growth factor-inducible protein 2A9) (MLN 4).

S10A9_MOUSE
θ value	8.67504e-11 (rank : 19)	NC score	0.911844 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	P31725	Gene names	S100a9, Cagb, Mrp14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain).

S10A3_MOUSE
θ value	1.9326e-10 (rank : 20)	NC score	0.823449 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P62818, P56566	Gene names	S100a3
Domain Architecture	No domain graphic available
Description	Protein S100-A3 (S100 calcium-binding protein A3) (Protein S-100E).

S10A9_HUMAN
θ value	1.9326e-10 (rank : 21)	NC score	0.879333 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P06702, Q9NYM0, Q9UCJ1	Gene names	S100A9, CAGB, MRP14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit).

S10A3_HUMAN
θ value	2.52405e-10 (rank : 22)	NC score	0.801367 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P33764	Gene names	S100A3, S100E
Domain Architecture
Description	Protein S100-A3 (S100 calcium-binding protein A3) (Protein S-100E).

S11Y_HUMAN
θ value	6.21693e-09 (rank : 23)	NC score	0.845825 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UDP3	Gene names
Domain Architecture
Description	Putative S100 calcium-binding protein H_NH0456N16.1.

S10AG_HUMAN
θ value	6.87365e-08 (rank : 24)	NC score	0.833247 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q96FQ6	Gene names	S100A16
Domain Architecture
Description	Protein S100-A16 (S100 calcium-binding protein A16) (Protein S100F).

HORN_MOUSE
θ value	1.17247e-07 (rank : 25)	NC score	0.607268 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	218	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

S100G_HUMAN
θ value	5.81887e-07 (rank : 26)	NC score	0.815594 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	P29377	Gene names	S100G, CABP9K, CALB3, S100D
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

FILA_HUMAN
θ value	1.69304e-06 (rank : 27)	NC score	0.334819 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

HORN_HUMAN
θ value	2.21117e-06 (rank : 28)	NC score	0.495244 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	206	Shared Neighborhood Hits	30
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

S10A8_MOUSE
θ value	2.21117e-06 (rank : 29)	NC score	0.811726 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	P27005, P31724	Gene names	S100a8, Caga, Mrp8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (P8) (Leukocyte L1 complex light chain) (Chemotactic cytokine CP-10) (Pro- inflammatory S100 cytokine).

RPTN_HUMAN
θ value	1.43324e-05 (rank : 30)	NC score	0.390788 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	406	Shared Neighborhood Hits	33
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

S100G_MOUSE
θ value	4.1701e-05 (rank : 31)	NC score	0.815318 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	P97816	Gene names	S100g, Calb3, S100d
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

S10A8_HUMAN
θ value	5.44631e-05 (rank : 32)	NC score	0.821838 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	P05109, Q9UC92, Q9UCJ0	Gene names	S100A8, CAGA, MRP8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (Calprotectin L1L subunit) (Urinary stone protein band A).

RPTN_MOUSE
θ value	0.000158464 (rank : 33)	NC score	0.250503 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TRHY_HUMAN
θ value	0.00020696 (rank : 34)	NC score	0.167970 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	1385	Shared Neighborhood Hits	36
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

S10AD_HUMAN
θ value	0.000270298 (rank : 35)	NC score	0.738328 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q99584	Gene names	S100A13
Domain Architecture
Description	Protein S100-A13 (S100 calcium-binding protein A13).

S10AD_MOUSE
θ value	0.000270298 (rank : 36)	NC score	0.728808 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P97352	Gene names	S100a13
Domain Architecture
Description	Protein S100-A13 (S100 calcium-binding protein A13).

S10A7_HUMAN
θ value	0.000602161 (rank : 37)	NC score	0.519102 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P31151, Q9H1E2	Gene names	S100A7, PSOR1
Domain Architecture
Description	Protein S100-A7 (S100 calcium-binding protein A7) (Psoriasin).

SA7L1_HUMAN
θ value	0.00175202 (rank : 38)	NC score	0.577617 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	33	Shared Neighborhood Hits	31
SwissProt Accessions	Q86SG5	Gene names	S100A7L1, S100A15
Domain Architecture
Description	Protein S100-A7-like 1 (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A15).

CABP2_HUMAN
θ value	0.00298849 (rank : 39)	NC score	0.131794 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_MOUSE
θ value	0.00390308 (rank : 40)	NC score	0.133622 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

GPDM_HUMAN
θ value	0.163984 (rank : 41)	NC score	0.095016 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

CABP5_MOUSE
θ value	0.47712 (rank : 42)	NC score	0.100417 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP3_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.116032 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.129542 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.129367 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP5_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.099497 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CANB1_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.101373 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.101346 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB2_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.080194 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

GPDM_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.080045 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

PLSI_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.074532 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	209	Shared Neighborhood Hits	31
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

PLST_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.040983 (rank : 82)
Query Neighborhood Hits	61	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

S10AE_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.369303 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D2Q8, Q9D1D8	Gene names	S100a14, S100a15
Domain Architecture
Description	Protein S100-A14 (S100 calcium-binding protein A14) (S114).

GUC1C_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.037634 (rank : 84)
Query Neighborhood Hits	61	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

S10AE_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.414068 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCY8, Q5RHT0	Gene names	S100A14, S100A15
Domain Architecture
Description	Protein S100-A14 (S100 calcium-binding protein A14) (S114).

CABP4_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.106353 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP4_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.118139 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CANB2_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.075762 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

PPE1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.029409 (rank : 85)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

FSCN1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.007827 (rank : 86)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

PLST_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.040275 (rank : 83)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

CABP7_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.089674 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	35
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.089674 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CALL3_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.059549 (rank : 72)
Query Neighborhood Hits	61	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALL5_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.066088 (rank : 69)
Query Neighborhood Hits	61	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.058525 (rank : 74)
Query Neighborhood Hits	61	Target Neighborhood Hits	229	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALM_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.067699 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.067699 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CALN1_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.082981 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.082939 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CETN1_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.057134 (rank : 75)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN1_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.055882 (rank : 76)
Query Neighborhood Hits	61	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CETN2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.052305 (rank : 79)
Query Neighborhood Hits	61	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.052885 (rank : 78)
Query Neighborhood Hits	61	Target Neighborhood Hits	211	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN3_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.051837 (rank : 81)
Query Neighborhood Hits	61	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.051841 (rank : 80)
Query Neighborhood Hits	61	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CHP2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.058574 (rank : 73)
Query Neighborhood Hits	61	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CHP2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.053933 (rank : 77)
Query Neighborhood Hits	61	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

KIP2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.066346 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.067777 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

SEMG1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.065252 (rank : 70)
Query Neighborhood Hits	61	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEMG2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.064689 (rank : 71)
Query Neighborhood Hits	61	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

TNNC1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.074127 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	219	Shared Neighborhood Hits	33
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.074081 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	221	Shared Neighborhood Hits	33
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.081932 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	234	Shared Neighborhood Hits	39
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

TNNC2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.082955 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	233	Shared Neighborhood Hits	39
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

Hits sorted by NC score

S100Z_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.23823e-49 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXG8	Gene names	S100Z
Domain Architecture
Description	Protein S100-Z (S100 calcium-binding protein Z).

S10A1_MOUSE
NC score	0.972094 (rank : 2)	θ value	5.79196e-23 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P56565, O88949	Gene names	S100a1
Domain Architecture
Description	Protein S100-A1 (S100 calcium-binding protein A1) (S-100 protein alpha subunit) (S-100 protein alpha chain).

S100P_HUMAN
NC score	0.965829 (rank : 3)	θ value	2.97466e-19 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	58	Shared Neighborhood Hits	51
SwissProt Accessions	P25815	Gene names	S100P, S100E
Domain Architecture
Description	Protein S100-P (S100 calcium-binding protein P).

S10A1_HUMAN
NC score	0.953230 (rank : 4)	θ value	1.16704e-23 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	52
SwissProt Accessions	P23297	Gene names	S100A1, S100A
Domain Architecture
Description	Protein S100-A1 (S100 calcium-binding protein A1) (S-100 protein alpha subunit) (S-100 protein alpha chain).

S100B_HUMAN
NC score	0.944547 (rank : 5)	θ value	1.38178e-16 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	P04271	Gene names	S100B
Domain Architecture
Description	Protein S100-B (S100 calcium-binding protein B) (S-100 protein beta subunit) (S-100 protein beta chain).

S100B_MOUSE
NC score	0.943560 (rank : 6)	θ value	1.058e-16 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	P50114	Gene names	S100b
Domain Architecture
Description	Protein S100-B (S100 calcium-binding protein B) (S-100 protein beta subunit) (S-100 protein beta chain).

S10A2_HUMAN
NC score	0.943211 (rank : 7)	θ value	2.60593e-15 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	P29034, O00266, Q9BU83	Gene names	S100A2, S100L
Domain Architecture
Description	Protein S100-A2 (S100 calcium-binding protein A2) (Protein S-100L) (CAN19).

S10A4_HUMAN
NC score	0.942983 (rank : 8)	θ value	7.32683e-18 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	P26447	Gene names	S100A4, CAPL, MTS1
Domain Architecture
Description	Protein S100-A4 (S100 calcium-binding protein A4) (Metastasin) (Protein Mts1) (Placental calcium-binding protein) (Calvasculin).

S10AA_MOUSE
NC score	0.931350 (rank : 9)	θ value	7.82807e-20 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	P08207	Gene names	S100a10, Cal1l
Domain Architecture
Description	Protein S100-A10 (S100 calcium-binding protein A10) (Calpactin-1 light chain) (Calpactin I light chain) (p10 protein) (p11) (Cellular ligand of annexin II).

S10AA_HUMAN
NC score	0.930003 (rank : 10)	θ value	1.47631e-18 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	P60903, P08206	Gene names	S100A10, ANX2LG, CAL1L, CLP11
Domain Architecture
Description	Protein S100-A10 (S100 calcium-binding protein A10) (Calpactin-1 light chain) (Calpactin I light chain) (p10 protein) (p11) (Cellular ligand of annexin II).

S10A5_MOUSE
NC score	0.924857 (rank : 11)	θ value	2.43908e-13 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	P63084, O88945, P82540	Gene names	S100a5, S100d
Domain Architecture	No domain graphic available
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).

S10AC_HUMAN
NC score	0.922352 (rank : 12)	θ value	1.02475e-11 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	P80511, P83219	Gene names	S100A12
Domain Architecture
Description	Protein S100-A12 (S100 calcium-binding protein A12) (Calgranulin-C) (CAGC) (CGRP) (Neutrophil S100 protein) (Calcium-binding protein in amniotic fluid 1) (CAAF1) (p6) [Contains: Calcitermin].

S10A4_MOUSE
NC score	0.921268 (rank : 13)	θ value	3.63628e-17 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	P07091, P20066	Gene names	S100a4, Capl, Mts1
Domain Architecture
Description	Protein S100-A4 (S100 calcium-binding protein A4) (Metastasin) (Protein Mts1) (Metastatic cell protein) (Placental calcium-binding protein) (18A2) (PEL98).

S10AB_MOUSE
NC score	0.917954 (rank : 14)	θ value	8.38298e-14 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	56	Shared Neighborhood Hits	45
SwissProt Accessions	P50543, Q545S1	Gene names	S100a11, S100c
Domain Architecture
Description	Protein S100-A11 (S100 calcium-binding protein A11) (Protein S100C) (Calgizzarin) (Endothelial monocyte-activating polypeptide) (EMAP).

S10A9_MOUSE
NC score	0.911844 (rank : 15)	θ value	8.67504e-11 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	P31725	Gene names	S100a9, Cagb, Mrp14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain).

S10AB_HUMAN
NC score	0.908995 (rank : 16)	θ value	5.43371e-13 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	P31949, Q5VTK0	Gene names	S100A11, MLN70, S100C
Domain Architecture
Description	Protein S100-A11 (S100 calcium-binding protein A11) (Protein S100C) (Calgizzarin) (MLN 70).

S10A5_HUMAN
NC score	0.894252 (rank : 17)	θ value	3.18553e-13 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	P33763	Gene names	S100A5, S100D
Domain Architecture
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).

S10A9_HUMAN
NC score	0.879333 (rank : 18)	θ value	1.9326e-10 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P06702, Q9NYM0, Q9UCJ1	Gene names	S100A9, CAGB, MRP14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit).

S10A6_HUMAN
NC score	0.872226 (rank : 19)	θ value	2.98157e-11 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P06703	Gene names	S100A6, CACY
Domain Architecture
Description	Protein S100-A6 (S100 calcium-binding protein A6) (Calcyclin) (Prolactin receptor-associated protein) (PRA) (Growth factor-inducible protein 2A9) (MLN 4).

S10A6_MOUSE
NC score	0.868728 (rank : 20)	θ value	2.28291e-11 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	57	Shared Neighborhood Hits	42
SwissProt Accessions	P14069	Gene names	S100a6, Cacy
Domain Architecture
Description	Protein S100-A6 (S100 calcium-binding protein A6) (Calcyclin) (Prolactin receptor-associated protein) (5B10).

S11Y_HUMAN
NC score	0.845825 (rank : 21)	θ value	6.21693e-09 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UDP3	Gene names
Domain Architecture
Description	Putative S100 calcium-binding protein H_NH0456N16.1.

S10AG_HUMAN
NC score	0.833247 (rank : 22)	θ value	6.87365e-08 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q96FQ6	Gene names	S100A16
Domain Architecture
Description	Protein S100-A16 (S100 calcium-binding protein A16) (Protein S100F).

S10A3_MOUSE
NC score	0.823449 (rank : 23)	θ value	1.9326e-10 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P62818, P56566	Gene names	S100a3
Domain Architecture	No domain graphic available
Description	Protein S100-A3 (S100 calcium-binding protein A3) (Protein S-100E).

S10A8_HUMAN
NC score	0.821838 (rank : 24)	θ value	5.44631e-05 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	P05109, Q9UC92, Q9UCJ0	Gene names	S100A8, CAGA, MRP8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (Calprotectin L1L subunit) (Urinary stone protein band A).

S100G_HUMAN
NC score	0.815594 (rank : 25)	θ value	5.81887e-07 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	P29377	Gene names	S100G, CABP9K, CALB3, S100D
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

S100G_MOUSE
NC score	0.815318 (rank : 26)	θ value	4.1701e-05 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	P97816	Gene names	S100g, Calb3, S100d
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

S10A8_MOUSE
NC score	0.811726 (rank : 27)	θ value	2.21117e-06 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	52	Shared Neighborhood Hits	42
SwissProt Accessions	P27005, P31724	Gene names	S100a8, Caga, Mrp8
Domain Architecture
Description	Protein S100-A8 (S100 calcium-binding protein A8) (Calgranulin-A) (Migration inhibitory factor-related protein 8) (MRP-8) (P8) (Leukocyte L1 complex light chain) (Chemotactic cytokine CP-10) (Pro- inflammatory S100 cytokine).

S10A3_HUMAN
NC score	0.801367 (rank : 28)	θ value	2.52405e-10 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P33764	Gene names	S100A3, S100E
Domain Architecture
Description	Protein S100-A3 (S100 calcium-binding protein A3) (Protein S-100E).

S10AD_HUMAN
NC score	0.738328 (rank : 29)	θ value	0.000270298 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q99584	Gene names	S100A13
Domain Architecture
Description	Protein S100-A13 (S100 calcium-binding protein A13).

S10AD_MOUSE
NC score	0.728808 (rank : 30)	θ value	0.000270298 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P97352	Gene names	S100a13
Domain Architecture
Description	Protein S100-A13 (S100 calcium-binding protein A13).

HORN_MOUSE
NC score	0.607268 (rank : 31)	θ value	1.17247e-07 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	218	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

SA7L1_HUMAN
NC score	0.577617 (rank : 32)	θ value	0.00175202 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	33	Shared Neighborhood Hits	31
SwissProt Accessions	Q86SG5	Gene names	S100A7L1, S100A15
Domain Architecture
Description	Protein S100-A7-like 1 (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A15).

S10A7_HUMAN
NC score	0.519102 (rank : 33)	θ value	0.000602161 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P31151, Q9H1E2	Gene names	S100A7, PSOR1
Domain Architecture
Description	Protein S100-A7 (S100 calcium-binding protein A7) (Psoriasin).

HORN_HUMAN
NC score	0.495244 (rank : 34)	θ value	2.21117e-06 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	206	Shared Neighborhood Hits	30
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

S10AE_HUMAN
NC score	0.414068 (rank : 35)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCY8, Q5RHT0	Gene names	S100A14, S100A15
Domain Architecture
Description	Protein S100-A14 (S100 calcium-binding protein A14) (S114).

RPTN_HUMAN
NC score	0.390788 (rank : 36)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	406	Shared Neighborhood Hits	33
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

S10AE_MOUSE
NC score	0.369303 (rank : 37)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D2Q8, Q9D1D8	Gene names	S100a14, S100a15
Domain Architecture
Description	Protein S100-A14 (S100 calcium-binding protein A14) (S114).

FILA_HUMAN
NC score	0.334819 (rank : 38)	θ value	1.69304e-06 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RPTN_MOUSE
NC score	0.250503 (rank : 39)	θ value	0.000158464 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TRHY_HUMAN
NC score	0.167970 (rank : 40)	θ value	0.00020696 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	1385	Shared Neighborhood Hits	36
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CABP2_MOUSE
NC score	0.133622 (rank : 41)	θ value	0.00390308 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_HUMAN
NC score	0.131794 (rank : 42)	θ value	0.00298849 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP1_HUMAN
NC score	0.129542 (rank : 43)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
NC score	0.129367 (rank : 44)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP4_MOUSE
NC score	0.118139 (rank : 45)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CABP3_HUMAN
NC score	0.116032 (rank : 46)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP4_HUMAN
NC score	0.106353 (rank : 47)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CANB1_HUMAN
NC score	0.101373 (rank : 48)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.101346 (rank : 49)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CABP5_MOUSE
NC score	0.100417 (rank : 50)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP5_HUMAN
NC score	0.099497 (rank : 51)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

GPDM_HUMAN
NC score	0.095016 (rank : 52)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

CABP7_HUMAN
NC score	0.089674 (rank : 53)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	35
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.089674 (rank : 54)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	205	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CALN1_HUMAN
NC score	0.082981 (rank : 55)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

TNNC2_MOUSE
NC score	0.082955 (rank : 56)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	61	Target Neighborhood Hits	233	Shared Neighborhood Hits	39
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CALN1_MOUSE
NC score	0.082939 (rank : 57)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

TNNC2_HUMAN
NC score	0.081932 (rank : 58)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	61	Target Neighborhood Hits	234	Shared Neighborhood Hits	39
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CANB2_HUMAN
NC score	0.080194 (rank : 59)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

GPDM_MOUSE
NC score	0.080045 (rank : 60)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

CANB2_MOUSE
NC score	0.075762 (rank : 61)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

PLSI_HUMAN
NC score	0.074532 (rank : 62)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	209	Shared Neighborhood Hits	31
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

TNNC1_HUMAN
NC score	0.074127 (rank : 63)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	61	Target Neighborhood Hits	219	Shared Neighborhood Hits	33
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_MOUSE
NC score	0.074081 (rank : 64)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	61	Target Neighborhood Hits	221	Shared Neighborhood Hits	33
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

KIP2_MOUSE
NC score	0.067777 (rank : 65)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	61	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

CALM_HUMAN
NC score	0.067699 (rank : 66)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.067699 (rank : 67)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	33
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

KIP2_HUMAN
NC score	0.066346 (rank : 68)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	61	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

CALL5_HUMAN
NC score	0.066088 (rank : 69)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

SEMG1_HUMAN
NC score	0.065252 (rank : 70)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	61	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SEMG2_HUMAN
NC score	0.064689 (rank : 71)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	61	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

CALL3_HUMAN
NC score	0.059549 (rank : 72)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CHP2_HUMAN
NC score	0.058574 (rank : 73)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	61	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CALM4_MOUSE
NC score	0.058525 (rank : 74)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	229	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CETN1_HUMAN
NC score	0.057134 (rank : 75)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	61	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN1_MOUSE
NC score	0.055882 (rank : 76)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	61	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CHP2_MOUSE
NC score	0.053933 (rank : 77)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	61	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

CETN2_MOUSE
NC score	0.052885 (rank : 78)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	61	Target Neighborhood Hits	211	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_HUMAN
NC score	0.052305 (rank : 79)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	61	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN3_MOUSE
NC score	0.051841 (rank : 80)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	61	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CETN3_HUMAN
NC score	0.051837 (rank : 81)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	61	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

PLST_MOUSE
NC score	0.040983 (rank : 82)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

PLST_HUMAN
NC score	0.040275 (rank : 83)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

GUC1C_HUMAN
NC score	0.037634 (rank : 84)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	148	Shared Neighborhood Hits	22
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

PPE1_HUMAN
NC score	0.029409 (rank : 85)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

FSCN1_HUMAN
NC score	0.007827 (rank : 86)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).