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Network neighborhood for query Sequence : DCE2_HUMAN

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DCE2_HUMAN
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DCE1_HUMAN
θ value	0 (rank : 1)	NC score	0.995625 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE1_MOUSE
θ value	0 (rank : 2)	NC score	0.995613 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE2_MOUSE
θ value	0 (rank : 4)	NC score	0.999703 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

CSAD_HUMAN
θ value	2.76981e-150 (rank : 5)	NC score	0.985657 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CSAD_MOUSE
θ value	5.77539e-148 (rank : 6)	NC score	0.984530 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

DDC_HUMAN
θ value	1.0531e-32 (rank : 7)	NC score	0.774092 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_MOUSE
θ value	1.16434e-31 (rank : 8)	NC score	0.770532 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCHS_HUMAN
θ value	4.57862e-28 (rank : 9)	NC score	0.737448 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_MOUSE
θ value	7.80994e-28 (rank : 10)	NC score	0.733996 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

SGPL1_HUMAN
θ value	0.00509761 (rank : 11)	NC score	0.161414 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_MOUSE
θ value	0.163984 (rank : 12)	NC score	0.136484 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

CAC1H_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.010262 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

MMSA_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.022366 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q02252, Q9UKM8	Gene names	ALDH6A1, MMSDH
Domain Architecture
Description	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18).

ADDG_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.016157 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYB5, Q9D2M5, Q9QYB6	Gene names	Add3, Addl
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

Hits sorted by NC score

DCE2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE2_MOUSE
NC score	0.999703 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_HUMAN
NC score	0.995625 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE1_MOUSE
NC score	0.995613 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

CSAD_HUMAN
NC score	0.985657 (rank : 5)	θ value	2.76981e-150 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CSAD_MOUSE
NC score	0.984530 (rank : 6)	θ value	5.77539e-148 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

DDC_HUMAN
NC score	0.774092 (rank : 7)	θ value	1.0531e-32 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_MOUSE
NC score	0.770532 (rank : 8)	θ value	1.16434e-31 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCHS_HUMAN
NC score	0.737448 (rank : 9)	θ value	4.57862e-28 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_MOUSE
NC score	0.733996 (rank : 10)	θ value	7.80994e-28 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

SGPL1_HUMAN
NC score	0.161414 (rank : 11)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_MOUSE
NC score	0.136484 (rank : 12)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

MMSA_HUMAN
NC score	0.022366 (rank : 13)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q02252, Q9UKM8	Gene names	ALDH6A1, MMSDH
Domain Architecture
Description	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18).

ADDG_MOUSE
NC score	0.016157 (rank : 14)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYB5, Q9D2M5, Q9QYB6	Gene names	Add3, Addl
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

CAC1H_HUMAN
NC score	0.010262 (rank : 15)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).