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Network neighborhood for query Sequence : DCHS_HUMAN

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DCHS_HUMAN
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DCHS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_MOUSE
θ value	0 (rank : 2)	NC score	0.997270 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DDC_MOUSE
θ value	1.20145e-153 (rank : 3)	NC score	0.981439 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_HUMAN
θ value	2.95929e-152 (rank : 4)	NC score	0.980715 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCE2_MOUSE
θ value	3.50572e-28 (rank : 5)	NC score	0.737303 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_HUMAN
θ value	4.57862e-28 (rank : 6)	NC score	0.734705 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE2_HUMAN
θ value	4.57862e-28 (rank : 7)	NC score	0.737448 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_MOUSE
θ value	2.96777e-27 (rank : 8)	NC score	0.729943 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

CSAD_HUMAN
θ value	4.01107e-24 (rank : 9)	NC score	0.730778 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CSAD_MOUSE
θ value	3.39556e-23 (rank : 10)	NC score	0.727419 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CN104_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.026791 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

FA5_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.010008 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

SGPL1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.067540 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

IFIT3_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.012234 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

ILF2_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.019007 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.019007 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

LRBA_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.006601 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NSD1_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.006594 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TMM25_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.011047 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

SGPL1_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.068077 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

Hits sorted by NC score

DCHS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_MOUSE
NC score	0.997270 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DDC_MOUSE
NC score	0.981439 (rank : 3)	θ value	1.20145e-153 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_HUMAN
NC score	0.980715 (rank : 4)	θ value	2.95929e-152 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCE2_HUMAN
NC score	0.737448 (rank : 5)	θ value	4.57862e-28 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE2_MOUSE
NC score	0.737303 (rank : 6)	θ value	3.50572e-28 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_HUMAN
NC score	0.734705 (rank : 7)	θ value	4.57862e-28 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

CSAD_HUMAN
NC score	0.730778 (rank : 8)	θ value	4.01107e-24 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

DCE1_MOUSE
NC score	0.729943 (rank : 9)	θ value	2.96777e-27 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

CSAD_MOUSE
NC score	0.727419 (rank : 10)	θ value	3.39556e-23 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

SGPL1_HUMAN
NC score	0.068077 (rank : 11)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_MOUSE
NC score	0.067540 (rank : 12)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

CN104_MOUSE
NC score	0.026791 (rank : 13)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BPI1, Q9CZC7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf104 homolog.

ILF2_HUMAN
NC score	0.019007 (rank : 14)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
NC score	0.019007 (rank : 15)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

IFIT3_MOUSE
NC score	0.012234 (rank : 16)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

TMM25_MOUSE
NC score	0.011047 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

FA5_HUMAN
NC score	0.010008 (rank : 18)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

LRBA_HUMAN
NC score	0.006601 (rank : 19)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NSD1_MOUSE
NC score	0.006594 (rank : 20)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).