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Network neighborhood for query Sequence : CSAD_HUMAN

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CSAD_HUMAN
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSAD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CSAD_MOUSE
θ value	0 (rank : 2)	NC score	0.998994 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

DCE2_HUMAN
θ value	2.76981e-150 (rank : 3)	NC score	0.985657 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE2_MOUSE
θ value	2.76981e-150 (rank : 4)	NC score	0.985283 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_HUMAN
θ value	8.0589e-150 (rank : 5)	NC score	0.985250 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE1_MOUSE
θ value	5.77539e-148 (rank : 6)	NC score	0.985023 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DDC_MOUSE
θ value	8.63488e-27 (rank : 7)	NC score	0.762694 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_HUMAN
θ value	1.47289e-26 (rank : 8)	NC score	0.765756 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCHS_MOUSE
θ value	4.73814e-25 (rank : 9)	NC score	0.728723 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_HUMAN
θ value	4.01107e-24 (rank : 10)	NC score	0.730778 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

SGPL1_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.132229 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.108386 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

SYAM_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.013220 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

NFS1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.029784 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1J3	Gene names	Nfs1, Nifs
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7) (m-Nfs1).

HERC2_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.008368 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.008362 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

ITSN2_HUMAN
θ value	8.99809 (rank : 17)	NC score	-0.000019 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1173	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SPYA_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.011968 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P21549	Gene names	AGXT, AGT1
Domain Architecture
Description	Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

Hits sorted by NC score

CSAD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

CSAD_MOUSE
NC score	0.998994 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

DCE2_HUMAN
NC score	0.985657 (rank : 3)	θ value	2.76981e-150 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE2_MOUSE
NC score	0.985283 (rank : 4)	θ value	2.76981e-150 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P48320, O35519	Gene names	Gad2, Gad65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

DCE1_HUMAN
NC score	0.985250 (rank : 5)	θ value	8.0589e-150 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q99259, Q9BU91, Q9UHH4	Gene names	GAD1, GAD, GAD67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DCE1_MOUSE
NC score	0.985023 (rank : 6)	θ value	5.77539e-148 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P48318, O08685	Gene names	Gad1, Gad67
Domain Architecture
Description	Glutamate decarboxylase 1 (EC 4.1.1.15) (Glutamate decarboxylase 67 kDa isoform) (GAD-67) (67 kDa glutamic acid decarboxylase).

DDC_HUMAN
NC score	0.765756 (rank : 7)	θ value	1.47289e-26 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P20711, Q16723	Gene names	DDC, AADC
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DDC_MOUSE
NC score	0.762694 (rank : 8)	θ value	8.63488e-27 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88533	Gene names	Ddc
Domain Architecture
Description	Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).

DCHS_HUMAN
NC score	0.730778 (rank : 9)	θ value	4.01107e-24 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DCHS_MOUSE
NC score	0.728723 (rank : 10)	θ value	4.73814e-25 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P23738	Gene names	Hdc
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

SGPL1_HUMAN
NC score	0.132229 (rank : 11)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_MOUSE
NC score	0.108386 (rank : 12)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

NFS1_MOUSE
NC score	0.029784 (rank : 13)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1J3	Gene names	Nfs1, Nifs
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7) (m-Nfs1).

SYAM_HUMAN
NC score	0.013220 (rank : 14)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

SPYA_HUMAN
NC score	0.011968 (rank : 15)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P21549	Gene names	AGXT, AGT1
Domain Architecture
Description	Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

HERC2_HUMAN
NC score	0.008368 (rank : 16)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
NC score	0.008362 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

ITSN2_HUMAN
NC score	-0.000019 (rank : 18)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1173	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).