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Network neighborhood for query Sequence : SPYA_HUMAN

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SPYA_HUMAN
SwissProt Accessions	P21549	Gene names	AGXT, AGT1
Domain Architecture
Description	Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPYA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P21549	Gene names	AGXT, AGT1
Domain Architecture
Description	Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

SPYA_MOUSE
θ value	1.72287e-176 (rank : 2)	NC score	0.993124 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	O35423	Gene names	Agxt, Agxt1
Domain Architecture
Description	Serine--pyruvate aminotransferase, mitochondrial precursor (EC 2.6.1.51) (SPT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

SGPL1_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.087628 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

PKHD1_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.066759 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

NFS1_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.111129 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y697, Q6P0L8, Q9NTZ5, Q9Y481	Gene names	NFS1, NIFS
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7).

NFS1_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.102713 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1J3	Gene names	Nfs1, Nifs
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7) (m-Nfs1).

MSI1H_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.025485 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	O43347, Q96PU0, Q96PU1, Q96PU2, Q96PU3	Gene names	MSI1
Domain Architecture	No domain graphic available
Description	RNA-binding protein Musashi homolog 1 (Musashi-1).

MSI1H_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.024869 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q61474, Q8BNC7	Gene names	Msi1, Msi1h
Domain Architecture	No domain graphic available
Description	RNA-binding protein Musashi homolog 1 (Musashi-1).

CSAD_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.011968 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

OSB10_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.009990 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

PISD_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.017667 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSF4, Q8BSD6	Gene names	Pisd
Domain Architecture
Description	Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65) [Contains: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain].

SGPL1_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.050846 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

Hits sorted by NC score

SPYA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P21549	Gene names	AGXT, AGT1
Domain Architecture
Description	Serine--pyruvate aminotransferase (EC 2.6.1.51) (SPT) (Alanine-- glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

SPYA_MOUSE
NC score	0.993124 (rank : 2)	θ value	1.72287e-176 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	O35423	Gene names	Agxt, Agxt1
Domain Architecture
Description	Serine--pyruvate aminotransferase, mitochondrial precursor (EC 2.6.1.51) (SPT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44) (AGT).

NFS1_HUMAN
NC score	0.111129 (rank : 3)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y697, Q6P0L8, Q9NTZ5, Q9Y481	Gene names	NFS1, NIFS
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7).

NFS1_MOUSE
NC score	0.102713 (rank : 4)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1J3	Gene names	Nfs1, Nifs
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7) (m-Nfs1).

SGPL1_HUMAN
NC score	0.087628 (rank : 5)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

PKHD1_HUMAN
NC score	0.066759 (rank : 6)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

SGPL1_MOUSE
NC score	0.050846 (rank : 7)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

MSI1H_HUMAN
NC score	0.025485 (rank : 8)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	O43347, Q96PU0, Q96PU1, Q96PU2, Q96PU3	Gene names	MSI1
Domain Architecture	No domain graphic available
Description	RNA-binding protein Musashi homolog 1 (Musashi-1).

MSI1H_MOUSE
NC score	0.024869 (rank : 9)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q61474, Q8BNC7	Gene names	Msi1, Msi1h
Domain Architecture	No domain graphic available
Description	RNA-binding protein Musashi homolog 1 (Musashi-1).

PISD_MOUSE
NC score	0.017667 (rank : 10)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSF4, Q8BSD6	Gene names	Pisd
Domain Architecture
Description	Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65) [Contains: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain].

CSAD_HUMAN
NC score	0.011968 (rank : 11)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y600, Q9UNJ5, Q9Y601	Gene names	CSAD, CSD
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

OSB10_HUMAN
NC score	0.009990 (rank : 12)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).