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Network neighborhood for query Sequence : HXK4_HUMAN

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HXK4_HUMAN
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HXK4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK4_MOUSE
θ value	0 (rank : 2)	NC score	0.999390 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P52792, P52791	Gene names	Gck, Gk
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK2_MOUSE
θ value	4.42207e-148 (rank : 3)	NC score	0.977742 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O08528	Gene names	Hk2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II).

HXK2_HUMAN
θ value	1.28662e-147 (rank : 4)	NC score	0.977904 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P52789, Q8WU87, Q9UN82	Gene names	HK2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase).

HXK1_HUMAN
θ value	9.54178e-143 (rank : 5)	NC score	0.977285 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P19367, O43443, O43444, O75574, Q5VTC3, Q96HC8, Q9NNZ4, Q9NNZ5	Gene names	HK1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain form hexokinase).

HXK1_MOUSE
θ value	9.87422e-140 (rank : 6)	NC score	0.976420 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P17710, Q61659, Q64476, Q64479	Gene names	Hk1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Hexokinase, tumor isozyme).

HXK3_MOUSE
θ value	1.16911e-132 (rank : 7)	NC score	0.976916 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK3_HUMAN
θ value	8.37844e-131 (rank : 8)	NC score	0.976613 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	P52790	Gene names	HK3
Domain Architecture
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

CROCC_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.020798 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	1460	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.019255 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	1409	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ARHG6_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.008808 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

FA76A_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.031459 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76A_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.026555 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

NOP5_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.021343 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

CCD19_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.007538 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	639	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

E2AK4_HUMAN
θ value	6.88961 (rank : 16)	NC score	-0.000125 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1012	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

SPAG5_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.007244 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	625	Shared Neighborhood Hits	8
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

UACA_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.002538 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1622	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BPAEA_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.004318 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1480	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAC1H_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.002865 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

INCE_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.008245 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	903	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

Hits sorted by NC score

HXK4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK4_MOUSE
NC score	0.999390 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	P52792, P52791	Gene names	Gck, Gk
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

HXK2_HUMAN
NC score	0.977904 (rank : 3)	θ value	1.28662e-147 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P52789, Q8WU87, Q9UN82	Gene names	HK2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase).

HXK2_MOUSE
NC score	0.977742 (rank : 4)	θ value	4.42207e-148 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O08528	Gene names	Hk2
Domain Architecture
Description	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II).

HXK1_HUMAN
NC score	0.977285 (rank : 5)	θ value	9.54178e-143 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P19367, O43443, O43444, O75574, Q5VTC3, Q96HC8, Q9NNZ4, Q9NNZ5	Gene names	HK1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain form hexokinase).

HXK3_MOUSE
NC score	0.976916 (rank : 6)	θ value	1.16911e-132 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TRM8, Q3TAX6, Q3UDP1, Q3UEA4	Gene names	Hk3
Domain Architecture	No domain graphic available
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK3_HUMAN
NC score	0.976613 (rank : 7)	θ value	8.37844e-131 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	P52790	Gene names	HK3
Domain Architecture
Description	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III).

HXK1_MOUSE
NC score	0.976420 (rank : 8)	θ value	9.87422e-140 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P17710, Q61659, Q64476, Q64479	Gene names	Hk1
Domain Architecture
Description	Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Hexokinase, tumor isozyme).

FA76A_HUMAN
NC score	0.031459 (rank : 9)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76A_MOUSE
NC score	0.026555 (rank : 10)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

NOP5_HUMAN
NC score	0.021343 (rank : 11)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

CROCC_MOUSE
NC score	0.020798 (rank : 12)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	1460	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_HUMAN
NC score	0.019255 (rank : 13)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	1409	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ARHG6_HUMAN
NC score	0.008808 (rank : 14)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

INCE_MOUSE
NC score	0.008245 (rank : 15)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	903	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

CCD19_HUMAN
NC score	0.007538 (rank : 16)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	639	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

SPAG5_HUMAN
NC score	0.007244 (rank : 17)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	625	Shared Neighborhood Hits	8
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

BPAEA_MOUSE
NC score	0.004318 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1480	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAC1H_HUMAN
NC score	0.002865 (rank : 19)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

UACA_HUMAN
NC score	0.002538 (rank : 20)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	1622	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

E2AK4_HUMAN
NC score	-0.000125 (rank : 21)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	1012	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).