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Network neighborhood for query Sequence : CCD47_HUMAN

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CCD47_HUMAN
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CC47_MOUSE
θ value	0 (rank : 1)	NC score	0.933362 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CCD47_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

LIN1_HUMAN
θ value	0.00665767 (rank : 3)	NC score	0.132291 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

PP2CG_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.122837 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

RGP1_MOUSE
θ value	0.0252991 (rank : 5)	NC score	0.141480 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

AN32B_MOUSE
θ value	0.0330416 (rank : 6)	NC score	0.149752 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

ATAD2_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.060369 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	322	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

UBF1_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.104609 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	415	Shared Neighborhood Hits	22
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

PP2CG_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.104766 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

CK5P2_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.061203 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	1433	Shared Neighborhood Hits	66
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

NEK1_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.022927 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	1311	Shared Neighborhood Hits	65
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

SET_MOUSE
θ value	0.21417 (rank : 12)	NC score	0.096516 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

FBXW7_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.038154 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

LEO1_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.116257 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	958	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

AN32B_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.121138 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

AN32E_HUMAN
θ value	0.47712 (rank : 16)	NC score	0.099377 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

RGP1_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.132696 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CL011_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.096615 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

LEO1_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.121573 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	946	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CCD39_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.052448 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	1026	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

NUCL_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.052532 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

TRPM7_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.041602 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

UBF1_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.102310 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

AN32C_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.126703 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

HTSF1_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.081182 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

NOP14_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.078487 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PKN3_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.011407 (rank : 136)
Query Neighborhood Hits	119	Target Neighborhood Hits	1009	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RUFY2_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.044389 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	1208	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

ZN318_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.057985 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	642	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

CCAR1_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.068223 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	444	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCD96_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.054427 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	704	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC9_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.095807 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

MYH1_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.043360 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH8_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.045115 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	1610	Shared Neighborhood Hits	60
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	1.38821 (rank : 35)	NC score	0.043877 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	1600	Shared Neighborhood Hits	55
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

REST_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.045611 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	1605	Shared Neighborhood Hits	63
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SMC2_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.050221 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	1405	Shared Neighborhood Hits	63
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SPT5H_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.068004 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	437	Shared Neighborhood Hits	9
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CASP_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.055030 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	1152	Shared Neighborhood Hits	55
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CDS1_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.040079 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P98191, Q8CGZ1	Gene names	Cds1, Cds
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CENPB_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.064271 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CUTL1_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.054004 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

IF2P_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.073510 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	889	Shared Neighborhood Hits	54
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MYT1L_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.081808 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	461	Shared Neighborhood Hits	25
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

MYT1_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.068397 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ZC313_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.081164 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CJ118_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.045977 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	1132	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

MYH2_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.042450 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	1491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PELP1_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.057091 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	709	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CCD45_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.046518 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	663	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MRE11_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.046663 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

MYT1L_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.069209 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	471	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NUCL_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.042207 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

S6A15_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.017200 (rank : 129)
Query Neighborhood Hits	119	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2J7	Gene names	SLC6A15, NTT73
Domain Architecture
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73 (Orphan transporter v7-3) (Solute carrier family 6 member 15).

SIAL_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.060056 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

TITIN_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.013995 (rank : 131)
Query Neighborhood Hits	119	Target Neighborhood Hits	2923	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI44_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.062850 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

AN32A_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.113195 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

AN32A_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.105436 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.105436 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

CASP_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.052941 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	1131	Shared Neighborhood Hits	57
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CD2L1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.021434 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	1463	Shared Neighborhood Hits	53
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CL011_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.075860 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

CUTL1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.050315 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	1574	Shared Neighborhood Hits	57
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GON4L_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.058092 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	555	Shared Neighborhood Hits	26
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GON4L_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.056019 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HUWE1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.037122 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.036885 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

JIP3_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.043995 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	1039	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KI21A_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.037657 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	1543	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.036836 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	1317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MYH1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.041615 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PLCB1_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.043515 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	614	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RPA1_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.041876 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

TRPM7_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.032749 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

A4_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.032122 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	20
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CCD46_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.044267 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	1405	Shared Neighborhood Hits	64
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CK051_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.073721 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60006, Q9CXK2, Q9Y269	Gene names	C11orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51.

CK051_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.071993 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60007, Q3UXV5, Q9CXK2, Q9Y269	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51 homolog.

ITSN1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.030653 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	1669	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

JIP3_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.044183 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	759	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

KIF14_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.025010 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	732	Shared Neighborhood Hits	41
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

MRCKB_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.022463 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	2180	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MY18A_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.045447 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.046165 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	1989	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RPO3G_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.072205 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NXY9, Q8K0W5, Q9CV05	Gene names	Polr3g
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase III subunit G (EC 2.7.7.6) (DNA-directed RNA polymerase III 32 kDa polypeptide) (RNA polymerase III C32 subunit).

SCN8A_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.012108 (rank : 134)
Query Neighborhood Hits	119	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.012047 (rank : 135)
Query Neighborhood Hits	119	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SET_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.072246 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

ANS4B_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.016179 (rank : 130)
Query Neighborhood Hits	119	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

EMSY_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.021341 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

HNRCL_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.062184 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	232	Shared Neighborhood Hits	21
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

NCKX1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.031315 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NEK1_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.012402 (rank : 133)
Query Neighborhood Hits	119	Target Neighborhood Hits	1129	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

NFM_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.029048 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	1328	Shared Neighborhood Hits	54
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RPA1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.036539 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

RPGR1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.078442 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	713	Shared Neighborhood Hits	47
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RYR1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.024830 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SEC20_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.049912 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.050676 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

STK10_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.018261 (rank : 128)
Query Neighborhood Hits	119	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STT3A_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.020907 (rank : 125)
Query Neighborhood Hits	119	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P46977	Gene names	STT3A, ITM1
Domain Architecture
Description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (EC 2.4.1.119) (Oligosaccharyl transferase subunit STT3A) (STT3- A) (B5) (Integral membrane protein 1) (TMC).

STT3A_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.020881 (rank : 126)
Query Neighborhood Hits	119	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P46978	Gene names	Stt3a, Itm1
Domain Architecture
Description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (EC 2.4.1.119) (Oligosaccharyl transferase subunit STT3A) (STT3- A) (B5) (Integral membrane protein 1).

LIPA3_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.036480 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.036107 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	636	Shared Neighborhood Hits	37
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MIER1_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.019240 (rank : 127)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

MST4_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.004513 (rank : 138)
Query Neighborhood Hits	119	Target Neighborhood Hits	860	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MYPT2_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.012662 (rank : 132)
Query Neighborhood Hits	119	Target Neighborhood Hits	707	Shared Neighborhood Hits	38
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYT1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.074162 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	475	Shared Neighborhood Hits	37
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NCOR1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.023248 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	521	Shared Neighborhood Hits	30
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PLCB1_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.037154 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	531	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PPIG_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.028058 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PTMA_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.133256 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RENT2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.059896 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RRMJ3_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.028436 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SPRL1_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.051477 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	403	Shared Neighborhood Hits	44
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SPT5H_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.054877 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	436	Shared Neighborhood Hits	8
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TCF8_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.007215 (rank : 137)
Query Neighborhood Hits	119	Target Neighborhood Hits	1057	Shared Neighborhood Hits	38
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

UACA_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.033232 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	1620	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ABTAP_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.052372 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	381	Shared Neighborhood Hits	33
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AN32D_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.068135 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

AN32E_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.081245 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	16
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

CALD1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.051972 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	959	Shared Neighborhood Hits	54
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCAR1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.056401 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CENPB_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.056527 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

ERIC1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.090963 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

HTSF1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.050301 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

IWS1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.056508 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	1241	Shared Neighborhood Hits	69
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.060750 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	1258	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NSBP1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.101611 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	681	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PELP1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.053661 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PTMA_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.101398 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.051089 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SEC63_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.054065 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	586	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.054383 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	601	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TCAL5_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.080308 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	806	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TNNT2_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.050782 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	433	Shared Neighborhood Hits	34
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TUR8_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.060625 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

Hits sorted by NC score

CCD47_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CC47_MOUSE
NC score	0.933362 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	245	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

AN32B_MOUSE
NC score	0.149752 (rank : 3)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

RGP1_MOUSE
NC score	0.141480 (rank : 4)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

PTMA_HUMAN
NC score	0.133256 (rank : 5)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RGP1_HUMAN
NC score	0.132696 (rank : 6)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LIN1_HUMAN
NC score	0.132291 (rank : 7)	θ value	0.00665767 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

AN32C_HUMAN
NC score	0.126703 (rank : 8)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

PP2CG_HUMAN
NC score	0.122837 (rank : 9)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

LEO1_MOUSE
NC score	0.121573 (rank : 10)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	946	Shared Neighborhood Hits	70
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

AN32B_HUMAN
NC score	0.121138 (rank : 11)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

LEO1_HUMAN
NC score	0.116257 (rank : 12)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	958	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

AN32A_HUMAN
NC score	0.113195 (rank : 13)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

AN32A_MOUSE
NC score	0.105436 (rank : 14)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.105436 (rank : 15)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

PP2CG_MOUSE
NC score	0.104766 (rank : 16)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

UBF1_HUMAN
NC score	0.104609 (rank : 17)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	415	Shared Neighborhood Hits	22
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.102310 (rank : 18)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

NSBP1_MOUSE
NC score	0.101611 (rank : 19)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	119	Target Neighborhood Hits	681	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PTMA_MOUSE
NC score	0.101398 (rank : 20)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

AN32E_HUMAN
NC score	0.099377 (rank : 21)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

CL011_MOUSE
NC score	0.096615 (rank : 22)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

SET_MOUSE
NC score	0.096516 (rank : 23)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

CCDC9_MOUSE
NC score	0.095807 (rank : 24)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

ERIC1_HUMAN
NC score	0.090963 (rank : 25)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	119	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

MYT1L_MOUSE
NC score	0.081808 (rank : 26)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	461	Shared Neighborhood Hits	25
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

AN32E_MOUSE
NC score	0.081245 (rank : 27)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	16
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

HTSF1_MOUSE
NC score	0.081182 (rank : 28)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

ZC313_HUMAN
NC score	0.081164 (rank : 29)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

TCAL5_HUMAN
NC score	0.080308 (rank : 30)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	119	Target Neighborhood Hits	806	Shared Neighborhood Hits	72
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NOP14_MOUSE
NC score	0.078487 (rank : 31)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

RPGR1_MOUSE
NC score	0.078442 (rank : 32)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	713	Shared Neighborhood Hits	47
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CL011_HUMAN
NC score	0.075860 (rank : 33)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVM9, Q86WE2, Q96HM2, Q9BTX2, Q9NTB6, Q9NVM5	Gene names	C12orf11
Domain Architecture	No domain graphic available
Description	Protein C12orf11 (Sarcoma antigen NY-SAR-95).

MYT1_HUMAN
NC score	0.074162 (rank : 34)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	475	Shared Neighborhood Hits	37
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

CK051_HUMAN
NC score	0.073721 (rank : 35)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60006, Q9CXK2, Q9Y269	Gene names	C11orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51.

IF2P_HUMAN
NC score	0.073510 (rank : 36)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	889	Shared Neighborhood Hits	54
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SET_HUMAN
NC score	0.072246 (rank : 37)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

RPO3G_MOUSE
NC score	0.072205 (rank : 38)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NXY9, Q8K0W5, Q9CV05	Gene names	Polr3g
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase III subunit G (EC 2.7.7.6) (DNA-directed RNA polymerase III 32 kDa polypeptide) (RNA polymerase III C32 subunit).

CK051_MOUSE
NC score	0.071993 (rank : 39)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P60007, Q3UXV5, Q9CXK2, Q9Y269	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf51 homolog.

MYT1L_HUMAN
NC score	0.069209 (rank : 40)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	471	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MYT1_MOUSE
NC score	0.068397 (rank : 41)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

CCAR1_HUMAN
NC score	0.068223 (rank : 42)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	444	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

AN32D_HUMAN
NC score	0.068135 (rank : 43)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

SPT5H_MOUSE
NC score	0.068004 (rank : 44)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	437	Shared Neighborhood Hits	9
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CENPB_HUMAN
NC score	0.064271 (rank : 45)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

TRI44_MOUSE
NC score	0.062850 (rank : 46)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

HNRCL_HUMAN
NC score	0.062184 (rank : 47)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	232	Shared Neighborhood Hits	21
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

CK5P2_HUMAN
NC score	0.061203 (rank : 48)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	1433	Shared Neighborhood Hits	66
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

IWS1_MOUSE
NC score	0.060750 (rank : 49)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	119	Target Neighborhood Hits	1258	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TUR8_MOUSE
NC score	0.060625 (rank : 50)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

ATAD2_HUMAN
NC score	0.060369 (rank : 51)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	322	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SIAL_MOUSE
NC score	0.060056 (rank : 52)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

RENT2_HUMAN
NC score	0.059896 (rank : 53)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

GON4L_HUMAN
NC score	0.058092 (rank : 54)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	555	Shared Neighborhood Hits	26
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ZN318_MOUSE
NC score	0.057985 (rank : 55)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	642	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

PELP1_MOUSE
NC score	0.057091 (rank : 56)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	709	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CENPB_MOUSE
NC score	0.056527 (rank : 57)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	119	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

IWS1_HUMAN
NC score	0.056508 (rank : 58)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	119	Target Neighborhood Hits	1241	Shared Neighborhood Hits	69
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCAR1_MOUSE
NC score	0.056401 (rank : 59)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

GON4L_MOUSE
NC score	0.056019 (rank : 60)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

CASP_MOUSE
NC score	0.055030 (rank : 61)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	1152	Shared Neighborhood Hits	55
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SPT5H_HUMAN
NC score	0.054877 (rank : 62)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	436	Shared Neighborhood Hits	8
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

CCD96_MOUSE
NC score	0.054427 (rank : 63)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	704	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

SEC63_MOUSE
NC score	0.054383 (rank : 64)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	119	Target Neighborhood Hits	601	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_HUMAN
NC score	0.054065 (rank : 65)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	119	Target Neighborhood Hits	586	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

CUTL1_MOUSE
NC score	0.054004 (rank : 66)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	1620	Shared Neighborhood Hits	60
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PELP1_HUMAN
NC score	0.053661 (rank : 67)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	119	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CASP_HUMAN
NC score	0.052941 (rank : 68)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	1131	Shared Neighborhood Hits	57
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

NUCL_HUMAN
NC score	0.052532 (rank : 69)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

CCD39_MOUSE
NC score	0.052448 (rank : 70)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	1026	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

ABTAP_MOUSE
NC score	0.052372 (rank : 71)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	381	Shared Neighborhood Hits	33
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CALD1_HUMAN
NC score	0.051972 (rank : 72)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	959	Shared Neighborhood Hits	54
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SPRL1_MOUSE
NC score	0.051477 (rank : 73)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	403	Shared Neighborhood Hits	44
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

PTMS_HUMAN
NC score	0.051089 (rank : 74)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	119	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

TNNT2_HUMAN
NC score	0.050782 (rank : 75)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	119	Target Neighborhood Hits	433	Shared Neighborhood Hits	34
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

SEC20_MOUSE
NC score	0.050676 (rank : 76)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

CUTL1_HUMAN
NC score	0.050315 (rank : 77)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	1574	Shared Neighborhood Hits	57
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

HTSF1_HUMAN
NC score	0.050301 (rank : 78)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	119	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

SMC2_HUMAN
NC score	0.050221 (rank : 79)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	1405	Shared Neighborhood Hits	63
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SEC20_HUMAN
NC score	0.049912 (rank : 80)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

MRE11_MOUSE
NC score	0.046663 (rank : 81)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

CCD45_MOUSE
NC score	0.046518 (rank : 82)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	663	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MY18A_MOUSE
NC score	0.046165 (rank : 83)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	1989	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CJ118_MOUSE
NC score	0.045977 (rank : 84)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	1132	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

REST_HUMAN
NC score	0.045611 (rank : 85)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	1605	Shared Neighborhood Hits	63
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MY18A_HUMAN
NC score	0.045447 (rank : 86)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH8_HUMAN
NC score	0.045115 (rank : 87)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	1610	Shared Neighborhood Hits	60
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RUFY2_HUMAN
NC score	0.044389 (rank : 88)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	1208	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CCD46_MOUSE
NC score	0.044267 (rank : 89)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	1405	Shared Neighborhood Hits	64
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

JIP3_MOUSE
NC score	0.044183 (rank : 90)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	759	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

JIP3_HUMAN
NC score	0.043995 (rank : 91)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	1039	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MYH8_MOUSE
NC score	0.043877 (rank : 92)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	1600	Shared Neighborhood Hits	55
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PLCB1_HUMAN
NC score	0.043515 (rank : 93)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	614	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

MYH1_MOUSE
NC score	0.043360 (rank : 94)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	1461	Shared Neighborhood Hits	49
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
NC score	0.042450 (rank : 95)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	1491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

NUCL_MOUSE
NC score	0.042207 (rank : 96)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

RPA1_MOUSE
NC score	0.041876 (rank : 97)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

MYH1_HUMAN
NC score	0.041615 (rank : 98)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

TRPM7_MOUSE
NC score	0.041602 (rank : 99)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

CDS1_MOUSE
NC score	0.040079 (rank : 100)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P98191, Q8CGZ1	Gene names	Cds1, Cds
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

FBXW7_HUMAN
NC score	0.038154 (rank : 101)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

KI21A_HUMAN
NC score	0.037657 (rank : 102)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	1543	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PLCB1_MOUSE
NC score	0.037154 (rank : 103)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	531	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

HUWE1_HUMAN
NC score	0.037122 (rank : 104)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.036885 (rank : 105)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

KI21A_MOUSE
NC score	0.036836 (rank : 106)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	1317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

RPA1_HUMAN
NC score	0.036539 (rank : 107)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

LIPA3_HUMAN
NC score	0.036480 (rank : 108)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
NC score	0.036107 (rank : 109)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	636	Shared Neighborhood Hits	37
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

UACA_MOUSE
NC score	0.033232 (rank : 110)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	1620	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TRPM7_HUMAN
NC score	0.032749 (rank : 111)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

A4_HUMAN
NC score	0.032122 (rank : 112)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	20
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

NCKX1_HUMAN
NC score	0.031315 (rank : 113)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ITSN1_MOUSE
NC score	0.030653 (rank : 114)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	1669	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NFM_HUMAN
NC score	0.029048 (rank : 115)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	1328	Shared Neighborhood Hits	54
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RRMJ3_MOUSE
NC score	0.028436 (rank : 116)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

PPIG_HUMAN
NC score	0.028058 (rank : 117)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

KIF14_HUMAN
NC score	0.025010 (rank : 118)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	732	Shared Neighborhood Hits	41
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

RYR1_HUMAN
NC score	0.024830 (rank : 119)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

NCOR1_MOUSE
NC score	0.023248 (rank : 120)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	521	Shared Neighborhood Hits	30
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NEK1_MOUSE
NC score	0.022927 (rank : 121)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	1311	Shared Neighborhood Hits	65
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

MRCKB_MOUSE
NC score	0.022463 (rank : 122)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	2180	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CD2L1_MOUSE
NC score	0.021434 (rank : 123)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	1463	Shared Neighborhood Hits	53
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

EMSY_MOUSE
NC score	0.021341 (rank : 124)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

STT3A_HUMAN
NC score	0.020907 (rank : 125)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P46977	Gene names	STT3A, ITM1
Domain Architecture
Description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (EC 2.4.1.119) (Oligosaccharyl transferase subunit STT3A) (STT3- A) (B5) (Integral membrane protein 1) (TMC).

STT3A_MOUSE
NC score	0.020881 (rank : 126)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P46978	Gene names	Stt3a, Itm1
Domain Architecture
Description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (EC 2.4.1.119) (Oligosaccharyl transferase subunit STT3A) (STT3- A) (B5) (Integral membrane protein 1).

MIER1_MOUSE
NC score	0.019240 (rank : 127)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

STK10_HUMAN
NC score	0.018261 (rank : 128)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

S6A15_HUMAN
NC score	0.017200 (rank : 129)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2J7	Gene names	SLC6A15, NTT73
Domain Architecture
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73 (Orphan transporter v7-3) (Solute carrier family 6 member 15).

ANS4B_HUMAN
NC score	0.016179 (rank : 130)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

TITIN_HUMAN
NC score	0.013995 (rank : 131)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	2923	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MYPT2_HUMAN
NC score	0.012662 (rank : 132)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	707	Shared Neighborhood Hits	38
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

NEK1_HUMAN
NC score	0.012402 (rank : 133)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	1129	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

SCN8A_HUMAN
NC score	0.012108 (rank : 134)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.012047 (rank : 135)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

PKN3_MOUSE
NC score	0.011407 (rank : 136)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	1009	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

TCF8_HUMAN
NC score	0.007215 (rank : 137)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	1057	Shared Neighborhood Hits	38
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

MST4_MOUSE
NC score	0.004513 (rank : 138)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	860	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).