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Network neighborhood for query Sequence : CAZA3_HUMAN

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CAZA3_HUMAN
SwissProt Accessions	Q96KX2, Q969J0	Gene names	CAPZA3, CAPAA3, GSG3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAZA3_HUMAN
θ value	5.01279e-176 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KX2, Q969J0	Gene names	CAPZA3, CAPAA3, GSG3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3).

CAZA3_MOUSE
θ value	2.58046e-164 (rank : 2)	NC score	0.999262 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P70190, Q9D4N3	Gene names	Capza3, Cappa3, Gsg3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (Germ cell- specific protein 3).

CAZA2_MOUSE
θ value	7.25919e-50 (rank : 3)	NC score	0.920211 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P47754	Gene names	Capza2, Cappa2
Domain Architecture
Description	F-actin capping protein alpha-2 subunit (CapZ alpha-2).

CAZA2_HUMAN
θ value	1.23823e-49 (rank : 4)	NC score	0.919682 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P47755	Gene names	CAPZA2
Domain Architecture
Description	F-actin capping protein alpha-2 subunit (CapZ alpha-2).

CAZA1_HUMAN
θ value	1.36902e-48 (rank : 5)	NC score	0.918408 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P52907, Q53FQ6, Q6FHD5	Gene names	CAPZA1
Domain Architecture
Description	F-actin capping protein alpha-1 subunit (CapZ alpha-1).

CAZA1_MOUSE
θ value	2.58187e-47 (rank : 6)	NC score	0.916200 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P47753, Q91YN7	Gene names	Capza1, Cappa1
Domain Architecture
Description	F-actin capping protein alpha-1 subunit (CapZ alpha-1).

CDK7_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.002922 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	833	Shared Neighborhood Hits	3
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

CDK7_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.002936 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

HMDH_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.042691 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P04035, Q8N190	Gene names	HMGCR
Domain Architecture
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

HMDH_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.042595 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

CEP27_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.021965 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVX0, Q9H9B3	Gene names	CEP27, C15orf25
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 27 kDa (Cep27 protein).

THYG_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.006250 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

UACA_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.001815 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1620	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

Hits sorted by NC score

CAZA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.01279e-176 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q96KX2, Q969J0	Gene names	CAPZA3, CAPAA3, GSG3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3).

CAZA3_MOUSE
NC score	0.999262 (rank : 2)	θ value	2.58046e-164 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	P70190, Q9D4N3	Gene names	Capza3, Cappa3, Gsg3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (Germ cell- specific protein 3).

CAZA2_MOUSE
NC score	0.920211 (rank : 3)	θ value	7.25919e-50 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P47754	Gene names	Capza2, Cappa2
Domain Architecture
Description	F-actin capping protein alpha-2 subunit (CapZ alpha-2).

CAZA2_HUMAN
NC score	0.919682 (rank : 4)	θ value	1.23823e-49 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P47755	Gene names	CAPZA2
Domain Architecture
Description	F-actin capping protein alpha-2 subunit (CapZ alpha-2).

CAZA1_HUMAN
NC score	0.918408 (rank : 5)	θ value	1.36902e-48 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P52907, Q53FQ6, Q6FHD5	Gene names	CAPZA1
Domain Architecture
Description	F-actin capping protein alpha-1 subunit (CapZ alpha-1).

CAZA1_MOUSE
NC score	0.916200 (rank : 6)	θ value	2.58187e-47 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P47753, Q91YN7	Gene names	Capza1, Cappa1
Domain Architecture
Description	F-actin capping protein alpha-1 subunit (CapZ alpha-1).

HMDH_HUMAN
NC score	0.042691 (rank : 7)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P04035, Q8N190	Gene names	HMGCR
Domain Architecture
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

HMDH_MOUSE
NC score	0.042595 (rank : 8)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

CEP27_HUMAN
NC score	0.021965 (rank : 9)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVX0, Q9H9B3	Gene names	CEP27, C15orf25
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 27 kDa (Cep27 protein).

THYG_HUMAN
NC score	0.006250 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

CDK7_MOUSE
NC score	0.002936 (rank : 11)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q03147, Q99KK3	Gene names	Cdk7, Cdkn7, Crk4, Mo15, Mpk-7
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinase) (CRK4).

CDK7_HUMAN
NC score	0.002922 (rank : 12)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	833	Shared Neighborhood Hits	3
SwissProt Accessions	P50613, Q9BS60, Q9UE19	Gene names	CDK7, MO15
Domain Architecture
Description	Cell division protein kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1).

UACA_MOUSE
NC score	0.001815 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1620	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).