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Network neighborhood for query Sequence : SORC2_HUMAN

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SORC2_HUMAN
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SORC1_HUMAN
θ value	0 (rank : 1)	NC score	0.980588 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

SORC1_MOUSE
θ value	0 (rank : 2)	NC score	0.979600 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

SORC2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SORC2_MOUSE
θ value	0 (rank : 4)	NC score	0.992881 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPR5	Gene names	Sorcs2
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SORC3_HUMAN
θ value	0 (rank : 5)	NC score	0.976781 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORC3_MOUSE
θ value	0 (rank : 6)	NC score	0.978401 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORL_MOUSE
θ value	2.17053e-70 (rank : 7)	NC score	0.465750 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SORL_HUMAN
θ value	3.13423e-69 (rank : 8)	NC score	0.462021 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORT_HUMAN
θ value	6.32992e-62 (rank : 9)	NC score	0.871421 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q99523, Q8IZ49	Gene names	SORT1
Domain Architecture
Description	Sortilin precursor (Neurotensin receptor 3) (NTR3) (NT3) (Glycoprotein 95) (Gp95) (100 kDa NT receptor).

SORT_MOUSE
θ value	1.19377e-60 (rank : 10)	NC score	0.871880 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHU5, Q3UHE2, Q8K043, Q9QXW6	Gene names	Sort1
Domain Architecture	No domain graphic available
Description	Sortilin precursor (Neurotensin receptor 3) (NTR3) (mNTR3).

CO9A1_HUMAN
θ value	0.0113563 (rank : 11)	NC score	0.027533 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO5A2_HUMAN
θ value	0.0193708 (rank : 12)	NC score	0.023048 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	760	Shared Neighborhood Hits	23
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO9A1_MOUSE
θ value	0.0431538 (rank : 13)	NC score	0.024833 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

NRX2A_HUMAN
θ value	0.0431538 (rank : 14)	NC score	0.030539 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.0431538 (rank : 15)	NC score	0.043416 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SPS2_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.030936 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q99611, Q9BUQ2	Gene names	SEPHS2, SPS2
Domain Architecture
Description	Selenide, water dikinase 2 (EC 2.7.9.3) (Selenophosphate synthetase 2) (Selenium donor protein 2).

WDR46_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.035761 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	243	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

LSD1_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.025573 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PKD1_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.052288 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

FOXH1_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.021610 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

PUNC_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.020367 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	501	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TBX15_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.012848 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

CGRE1_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.026473 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

AAPK1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.003118 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	842	Shared Neighborhood Hits	8
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

AAPK1_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.003131 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

LTBP2_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.025187 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NEK3_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.002125 (rank : 82)
Query Neighborhood Hits	66	Target Neighborhood Hits	854	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

NACAM_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.011631 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SPEG_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.004811 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	1762	Shared Neighborhood Hits	29
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SSBP4_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.014573 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TNR16_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.021538 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

IRX5_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.010873 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

PDZD2_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.011796 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	772	Shared Neighborhood Hits	12
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TBX21_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.011607 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

ZAR1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.024255 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ITB5_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.008357 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NOS1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.009279 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SMOO_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.014226 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TITIN_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.011413 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	2923	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GLI1_HUMAN
θ value	3.0926 (rank : 40)	NC score	-0.000308 (rank : 85)
Query Neighborhood Hits	66	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

TARA_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.010260 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	1133	Shared Neighborhood Hits	15
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DRP2_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.008321 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

MY18B_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.004814 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	1299	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PCLO_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.009585 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PI5PA_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.011198 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	749	Shared Neighborhood Hits	27
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PLOD3_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.010744 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0E1, Q542E0, Q9CYY9	Gene names	Plod3
Domain Architecture
Description	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3).

PO121_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.011908 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PSG7_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.005136 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	239	Shared Neighborhood Hits	5
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

RIMB1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.008745 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	1479	Shared Neighborhood Hits	20
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.011374 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	1376	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SEN54_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.015217 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

CRTC1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.012122 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	230	Shared Neighborhood Hits	8
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CUL7_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.024519 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

NFH_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.005374 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	2247	Shared Neighborhood Hits	30
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SEM6C_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.004539 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

TNR16_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.019329 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

WDR46_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.024625 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

DMRTD_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.010956 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DOK7_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.012611 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

SHAN1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.008883 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	1041	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TLK2_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.001118 (rank : 83)
Query Neighborhood Hits	66	Target Neighborhood Hits	1044	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

CO4A2_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.013572 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	492	Shared Neighborhood Hits	15
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

FBX41_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.006987 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	430	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

TARA_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.007647 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCGAP_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.005727 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	872	Shared Neighborhood Hits	25
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ULK1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.000613 (rank : 84)
Query Neighborhood Hits	66	Target Neighborhood Hits	1214	Shared Neighborhood Hits	16
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

CD320_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.068771 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LDLR_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051795 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.053326 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	382	Shared Neighborhood Hits	5
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP12_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.052606 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.050932 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.051665 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	606	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.053681 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.058027 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	573	Shared Neighborhood Hits	4
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP3_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.053551 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.050369 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	355	Shared Neighborhood Hits	3
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.050399 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.052208 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.051946 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.052879 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.053225 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.053167 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	346	Shared Neighborhood Hits	3
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.053552 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VLDLR_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.054354 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.056497 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

Hits sorted by NC score

SORC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SORC2_MOUSE
NC score	0.992881 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPR5	Gene names	Sorcs2
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

SORC1_HUMAN
NC score	0.980588 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

SORC1_MOUSE
NC score	0.979600 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

SORC3_MOUSE
NC score	0.978401 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORC3_HUMAN
NC score	0.976781 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORT_MOUSE
NC score	0.871880 (rank : 7)	θ value	1.19377e-60 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PHU5, Q3UHE2, Q8K043, Q9QXW6	Gene names	Sort1
Domain Architecture	No domain graphic available
Description	Sortilin precursor (Neurotensin receptor 3) (NTR3) (mNTR3).

SORT_HUMAN
NC score	0.871421 (rank : 8)	θ value	6.32992e-62 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q99523, Q8IZ49	Gene names	SORT1
Domain Architecture
Description	Sortilin precursor (Neurotensin receptor 3) (NTR3) (NT3) (Glycoprotein 95) (Gp95) (100 kDa NT receptor).

SORL_MOUSE
NC score	0.465750 (rank : 9)	θ value	2.17053e-70 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SORL_HUMAN
NC score	0.462021 (rank : 10)	θ value	3.13423e-69 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CD320_HUMAN
NC score	0.068771 (rank : 11)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LRP2_HUMAN
NC score	0.058027 (rank : 12)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	573	Shared Neighborhood Hits	4
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

VLDLR_MOUSE
NC score	0.056497 (rank : 13)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	66	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_HUMAN
NC score	0.054354 (rank : 14)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	66	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP1_HUMAN
NC score	0.053681 (rank : 15)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP8_MOUSE
NC score	0.053552 (rank : 16)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	66	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP3_HUMAN
NC score	0.053551 (rank : 17)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LDLR_MOUSE
NC score	0.053326 (rank : 18)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	382	Shared Neighborhood Hits	5
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP6_MOUSE
NC score	0.053225 (rank : 19)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
NC score	0.053167 (rank : 20)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	66	Target Neighborhood Hits	346	Shared Neighborhood Hits	3
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP6_HUMAN
NC score	0.052879 (rank : 21)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP12_MOUSE
NC score	0.052606 (rank : 22)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

PKD1_HUMAN
NC score	0.052288 (rank : 23)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

LRP5_HUMAN
NC score	0.052208 (rank : 24)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
NC score	0.051946 (rank : 25)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LDLR_HUMAN
NC score	0.051795 (rank : 26)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_MOUSE
NC score	0.051665 (rank : 27)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	606	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
NC score	0.050932 (rank : 28)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP4_MOUSE
NC score	0.050399 (rank : 29)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP4_HUMAN
NC score	0.050369 (rank : 30)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	355	Shared Neighborhood Hits	3
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NRX2B_HUMAN
NC score	0.043416 (rank : 31)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

WDR46_MOUSE
NC score	0.035761 (rank : 32)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	243	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

SPS2_HUMAN
NC score	0.030936 (rank : 33)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q99611, Q9BUQ2	Gene names	SEPHS2, SPS2
Domain Architecture
Description	Selenide, water dikinase 2 (EC 2.7.9.3) (Selenophosphate synthetase 2) (Selenium donor protein 2).

NRX2A_HUMAN
NC score	0.030539 (rank : 34)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CO9A1_HUMAN
NC score	0.027533 (rank : 35)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CGRE1_HUMAN
NC score	0.026473 (rank : 36)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

LSD1_HUMAN
NC score	0.025573 (rank : 37)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LTBP2_HUMAN
NC score	0.025187 (rank : 38)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CO9A1_MOUSE
NC score	0.024833 (rank : 39)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

WDR46_HUMAN
NC score	0.024625 (rank : 40)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

CUL7_HUMAN
NC score	0.024519 (rank : 41)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

ZAR1_HUMAN
NC score	0.024255 (rank : 42)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CO5A2_HUMAN
NC score	0.023048 (rank : 43)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	760	Shared Neighborhood Hits	23
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FOXH1_HUMAN
NC score	0.021610 (rank : 44)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

TNR16_MOUSE
NC score	0.021538 (rank : 45)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

PUNC_MOUSE
NC score	0.020367 (rank : 46)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	501	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TNR16_HUMAN
NC score	0.019329 (rank : 47)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

SEN54_HUMAN
NC score	0.015217 (rank : 48)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

SSBP4_HUMAN
NC score	0.014573 (rank : 49)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SMOO_HUMAN
NC score	0.014226 (rank : 50)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CO4A2_MOUSE
NC score	0.013572 (rank : 51)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	492	Shared Neighborhood Hits	15
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

TBX15_MOUSE
NC score	0.012848 (rank : 52)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

DOK7_MOUSE
NC score	0.012611 (rank : 53)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CRTC1_MOUSE
NC score	0.012122 (rank : 54)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	230	Shared Neighborhood Hits	8
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

PO121_MOUSE
NC score	0.011908 (rank : 55)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PDZD2_HUMAN
NC score	0.011796 (rank : 56)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	772	Shared Neighborhood Hits	12
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

NACAM_MOUSE
NC score	0.011631 (rank : 57)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TBX21_HUMAN
NC score	0.011607 (rank : 58)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TITIN_HUMAN
NC score	0.011413 (rank : 59)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	2923	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RIMB1_MOUSE
NC score	0.011374 (rank : 60)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	1376	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PI5PA_HUMAN
NC score	0.011198 (rank : 61)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	749	Shared Neighborhood Hits	27
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

DMRTD_HUMAN
NC score	0.010956 (rank : 62)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

IRX5_MOUSE
NC score	0.010873 (rank : 63)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

PLOD3_MOUSE
NC score	0.010744 (rank : 64)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0E1, Q542E0, Q9CYY9	Gene names	Plod3
Domain Architecture
Description	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3).

TARA_MOUSE
NC score	0.010260 (rank : 65)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	1133	Shared Neighborhood Hits	15
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PCLO_MOUSE
NC score	0.009585 (rank : 66)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NOS1_HUMAN
NC score	0.009279 (rank : 67)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SHAN1_HUMAN
NC score	0.008883 (rank : 68)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	1041	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RIMB1_HUMAN
NC score	0.008745 (rank : 69)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	1479	Shared Neighborhood Hits	20
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ITB5_MOUSE
NC score	0.008357 (rank : 70)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

DRP2_HUMAN
NC score	0.008321 (rank : 71)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

TARA_HUMAN
NC score	0.007647 (rank : 72)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FBX41_MOUSE
NC score	0.006987 (rank : 73)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	430	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

TCGAP_HUMAN
NC score	0.005727 (rank : 74)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	872	Shared Neighborhood Hits	25
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NFH_MOUSE
NC score	0.005374 (rank : 75)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	2247	Shared Neighborhood Hits	30
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PSG7_HUMAN
NC score	0.005136 (rank : 76)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	239	Shared Neighborhood Hits	5
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

MY18B_HUMAN
NC score	0.004814 (rank : 77)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	1299	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SPEG_HUMAN
NC score	0.004811 (rank : 78)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	1762	Shared Neighborhood Hits	29
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SEM6C_MOUSE
NC score	0.004539 (rank : 79)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

AAPK1_MOUSE
NC score	0.003131 (rank : 80)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q5EG47	Gene names	Prkaa1
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

AAPK1_HUMAN
NC score	0.003118 (rank : 81)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	842	Shared Neighborhood Hits	8
SwissProt Accessions	Q13131, O00286, Q5D0E1, Q9UNQ4	Gene names	PRKAA1, AMPK1
Domain Architecture
Description	5'-AMP-activated protein kinase catalytic subunit alpha-1 (EC 2.7.11.1) (AMPK alpha-1 chain).

NEK3_MOUSE
NC score	0.002125 (rank : 82)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	854	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

TLK2_HUMAN
NC score	0.001118 (rank : 83)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	1044	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

ULK1_MOUSE
NC score	0.000613 (rank : 84)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	1214	Shared Neighborhood Hits	16
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

GLI1_HUMAN
NC score	-0.000308 (rank : 85)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).