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Network neighborhood for query Sequence : DKK1_HUMAN

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DKK1_HUMAN
SwissProt Accessions	O94907	Gene names	DKK1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (hDkk-1) (SK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DKK1_HUMAN
θ value	6.59259e-152 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	O94907	Gene names	DKK1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (hDkk-1) (SK).

DKK1_MOUSE
θ value	4.60808e-121 (rank : 2)	NC score	0.995128 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O54908	Gene names	Dkk1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (mDkk-1).

DKK2_MOUSE
θ value	1.01294e-51 (rank : 3)	NC score	0.935500 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

DKK2_HUMAN
θ value	2.94719e-51 (rank : 4)	NC score	0.935493 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

DKK4_MOUSE
θ value	3.86705e-35 (rank : 5)	NC score	0.912771 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEJ3	Gene names	Dkk4
Domain Architecture	No domain graphic available
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4).

DKK4_HUMAN
θ value	6.59618e-35 (rank : 6)	NC score	0.901966 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBT3, Q9Y4C3	Gene names	DKK4
Domain Architecture
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4) (hDkk-4) [Contains: Dickkopf-related protein 4 short form].

DKK3_HUMAN
θ value	8.97725e-08 (rank : 7)	NC score	0.480967 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	74	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	1.53129e-07 (rank : 8)	NC score	0.474241 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

PROK1_HUMAN
θ value	0.0193708 (rank : 9)	NC score	0.398784 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P58294	Gene names	PROK1
Domain Architecture
Description	Prokineticin-1 precursor (Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine).

PROK2_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.283090 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC23	Gene names	PROK2, BV8
Domain Architecture
Description	Prokineticin-2 precursor (PK2) (Protein Bv8 homolog).

GAS1_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.079455 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

PROK2_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.267094 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXU7, Q9QXU5, Q9QXU6	Gene names	Prok2, Bv8
Domain Architecture
Description	Prokineticin-2 precursor (PK2) (Protein Bv8 homolog).

MEGF6_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.028551 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	671	Shared Neighborhood Hits	14
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC1_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.015161 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	916	Shared Neighborhood Hits	13
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TRAF5_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.013369 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

COL_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.047514 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQC2, Q8VHR2, Q8VHR3	Gene names	Clps
Domain Architecture
Description	Colipase precursor.

FA12_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.006030 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

GAS1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.067175 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

LTBP4_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.019395 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN2_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.017842 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	560	Shared Neighborhood Hits	12
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.017929 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	549	Shared Neighborhood Hits	12
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

COL_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.041865 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P04118	Gene names	CLPS
Domain Architecture
Description	Colipase precursor.

FBN3_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.015040 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	543	Shared Neighborhood Hits	9
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MEGF8_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.012900 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NICE1_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.290502 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

Hits sorted by NC score

DKK1_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.59259e-152 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	O94907	Gene names	DKK1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (hDkk-1) (SK).

DKK1_MOUSE
NC score	0.995128 (rank : 2)	θ value	4.60808e-121 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O54908	Gene names	Dkk1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (mDkk-1).

DKK2_MOUSE
NC score	0.935500 (rank : 3)	θ value	1.01294e-51 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

DKK2_HUMAN
NC score	0.935493 (rank : 4)	θ value	2.94719e-51 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

DKK4_MOUSE
NC score	0.912771 (rank : 5)	θ value	3.86705e-35 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEJ3	Gene names	Dkk4
Domain Architecture	No domain graphic available
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4).

DKK4_HUMAN
NC score	0.901966 (rank : 6)	θ value	6.59618e-35 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBT3, Q9Y4C3	Gene names	DKK4
Domain Architecture
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4) (hDkk-4) [Contains: Dickkopf-related protein 4 short form].

DKK3_HUMAN
NC score	0.480967 (rank : 7)	θ value	8.97725e-08 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	74	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
NC score	0.474241 (rank : 8)	θ value	1.53129e-07 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

PROK1_HUMAN
NC score	0.398784 (rank : 9)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P58294	Gene names	PROK1
Domain Architecture
Description	Prokineticin-1 precursor (Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine).

NICE1_HUMAN
NC score	0.290502 (rank : 10)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

PROK2_HUMAN
NC score	0.283090 (rank : 11)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC23	Gene names	PROK2, BV8
Domain Architecture
Description	Prokineticin-2 precursor (PK2) (Protein Bv8 homolog).

PROK2_MOUSE
NC score	0.267094 (rank : 12)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXU7, Q9QXU5, Q9QXU6	Gene names	Prok2, Bv8
Domain Architecture
Description	Prokineticin-2 precursor (PK2) (Protein Bv8 homolog).

GAS1_MOUSE
NC score	0.079455 (rank : 13)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

GAS1_HUMAN
NC score	0.067175 (rank : 14)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

COL_MOUSE
NC score	0.047514 (rank : 15)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQC2, Q8VHR2, Q8VHR3	Gene names	Clps
Domain Architecture
Description	Colipase precursor.

COL_HUMAN
NC score	0.041865 (rank : 16)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P04118	Gene names	CLPS
Domain Architecture
Description	Colipase precursor.

MEGF6_HUMAN
NC score	0.028551 (rank : 17)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	671	Shared Neighborhood Hits	14
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LTBP4_MOUSE
NC score	0.019395 (rank : 18)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN2_MOUSE
NC score	0.017929 (rank : 19)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	549	Shared Neighborhood Hits	12
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.017842 (rank : 20)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	560	Shared Neighborhood Hits	12
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC1_MOUSE
NC score	0.015161 (rank : 21)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	916	Shared Neighborhood Hits	13
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBN3_HUMAN
NC score	0.015040 (rank : 22)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	543	Shared Neighborhood Hits	9
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

TRAF5_HUMAN
NC score	0.013369 (rank : 23)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

MEGF8_HUMAN
NC score	0.012900 (rank : 24)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FA12_HUMAN
NC score	0.006030 (rank : 25)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].