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Network neighborhood for query Sequence : PAPS2_MOUSE

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PAPS2_MOUSE
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAPS1_HUMAN
θ value	0 (rank : 1)	NC score	0.996356 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_MOUSE
θ value	0 (rank : 2)	NC score	0.996211 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS2_HUMAN
θ value	0 (rank : 3)	NC score	0.999247 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	O95340, Q9BZL2, Q9P0G6, Q9UHM1, Q9UKD3, Q9UP30	Gene names	PAPSS2, ATPSK2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

HS12B_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.049935 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

ARL1_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.021477 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	P40616, P80417	Gene names	ARL1
Domain Architecture
Description	ADP-ribosylation factor-like protein 1.

ARL1_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.021572 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	215	Shared Neighborhood Hits	6
SwissProt Accessions	P61211, P41276	Gene names	Arl1
Domain Architecture
Description	ADP-ribosylation factor-like protein 1.

U334_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.094835 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSD7	Gene names	C1orf57
Domain Architecture	No domain graphic available
Description	Probable UPF0334 kinase-like protein C1orf57.

ARD1_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.018110 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	621	Shared Neighborhood Hits	6
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.018279 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

HS12B_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.037503 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

MCM3_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.029035 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

MCM3_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.029043 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

RYR1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.009594 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

MDR1_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.003811 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

CUTL2_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.004352 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	906	Shared Neighborhood Hits	3
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MYO5C_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.000788 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	1206	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

Hits sorted by NC score

PAPS2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS2_HUMAN
NC score	0.999247 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	O95340, Q9BZL2, Q9P0G6, Q9UHM1, Q9UKD3, Q9UP30	Gene names	PAPSS2, ATPSK2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_HUMAN
NC score	0.996356 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_MOUSE
NC score	0.996211 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

U334_HUMAN
NC score	0.094835 (rank : 5)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSD7	Gene names	C1orf57
Domain Architecture	No domain graphic available
Description	Probable UPF0334 kinase-like protein C1orf57.

HS12B_HUMAN
NC score	0.049935 (rank : 6)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

HS12B_MOUSE
NC score	0.037503 (rank : 7)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

MCM3_MOUSE
NC score	0.029043 (rank : 8)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

MCM3_HUMAN
NC score	0.029035 (rank : 9)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

ARL1_MOUSE
NC score	0.021572 (rank : 10)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	215	Shared Neighborhood Hits	6
SwissProt Accessions	P61211, P41276	Gene names	Arl1
Domain Architecture
Description	ADP-ribosylation factor-like protein 1.

ARL1_HUMAN
NC score	0.021477 (rank : 11)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	P40616, P80417	Gene names	ARL1
Domain Architecture
Description	ADP-ribosylation factor-like protein 1.

ARD1_MOUSE
NC score	0.018279 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

ARD1_HUMAN
NC score	0.018110 (rank : 13)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	621	Shared Neighborhood Hits	6
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

RYR1_HUMAN
NC score	0.009594 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

CUTL2_HUMAN
NC score	0.004352 (rank : 15)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	906	Shared Neighborhood Hits	3
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MDR1_HUMAN
NC score	0.003811 (rank : 16)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MYO5C_HUMAN
NC score	0.000788 (rank : 17)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	1206	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).