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Network neighborhood for query Sequence : RT35_HUMAN

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RT35_HUMAN
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RT35_HUMAN
θ value	1.07914e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

RT35_MOUSE
θ value	2.77624e-142 (rank : 2)	NC score	0.963876 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

ITK_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.017654 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	1016	Shared Neighborhood Hits	7
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ATX2_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.053191 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

AMOT_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.049396 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	712	Shared Neighborhood Hits	25
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

K1543_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.079893 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	497	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TITIN_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.018682 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	2923	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLE4_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.037461 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	477	Shared Neighborhood Hits	16
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	0.365318 (rank : 9)	NC score	0.037471 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	482	Shared Neighborhood Hits	16
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

ZIM10_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.060893 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.061155 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	430	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

RAD50_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.039902 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	1317	Shared Neighborhood Hits	30
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.038004 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	1366	Shared Neighborhood Hits	28
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

YLPM1_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.057620 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

NP1L3_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.039294 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

SF01_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.048215 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ESX1L_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.015475 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

ITK_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.015730 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	985	Shared Neighborhood Hits	7
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

ROBO3_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.015876 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

TP53B_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.054966 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	644	Shared Neighborhood Hits	22
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BMX_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.017974 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	942	Shared Neighborhood Hits	7
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CK024_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.041436 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CKAP4_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.031192 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CTGE4_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.030445 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	393	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

NUF2_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.039006 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	585	Shared Neighborhood Hits	16
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

SETD2_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.031207 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	412	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMC2_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.034413 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

ARI4A_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.041471 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	434	Shared Neighborhood Hits	12
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ATS12_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.010393 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	251	Shared Neighborhood Hits	3
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CLSPN_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.032406 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

HCFC1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.039334 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.039693 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

PCLO_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.036633 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	2275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

POGZ_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.012263 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RUFY2_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.022645 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1208	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

C8AP2_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.031378 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	548	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

COVA1_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.035288 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

HMMR_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.028215 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	1082	Shared Neighborhood Hits	24
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PCLO_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.038491 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHF14_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.022227 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PRR12_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.037167 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RTN4_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.029010 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SMC2_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.035351 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	1131	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

BMX_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.013737 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	912	Shared Neighborhood Hits	6
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

DIAP2_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.017672 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

HXB2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.009070 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

PAR14_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.020165 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

RIN3_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.022307 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	239	Shared Neighborhood Hits	10
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ANX11_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.013185 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

BPAEA_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.019381 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	1480	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

G3PT_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.019825 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

K1543_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.056951 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NUF2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.035630 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	661	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PPIG_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.018383 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	670	Shared Neighborhood Hits	20
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TCRG1_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.028475 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	929	Shared Neighborhood Hits	25
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

ABCF1_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.015902 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

CSKI2_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.008847 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DNMBP_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.014557 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

LIPA3_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.016044 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	828	Shared Neighborhood Hits	15
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MNT_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.025491 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	19
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PIBF1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.021444 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

POLH_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.028867 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

SF3A2_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.034217 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.033193 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

ANR12_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.016836 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	1081	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GP126_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.005808 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

IF35_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.022563 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

PTN23_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.012267 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

REST_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.021032 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	1605	Shared Neighborhood Hits	30
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SRCA_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.011050 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TREF1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.010329 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	682	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

WASIP_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.018836 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YLPM1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.042150 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	670	Shared Neighborhood Hits	18
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

RT35_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.07914e-178 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

RT35_MOUSE
NC score	0.963876 (rank : 2)	θ value	2.77624e-142 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

K1543_MOUSE
NC score	0.079893 (rank : 3)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	497	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ZIM10_MOUSE
NC score	0.061155 (rank : 4)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	430	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_HUMAN
NC score	0.060893 (rank : 5)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

YLPM1_MOUSE
NC score	0.057620 (rank : 6)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

K1543_HUMAN
NC score	0.056951 (rank : 7)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TP53B_MOUSE
NC score	0.054966 (rank : 8)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	644	Shared Neighborhood Hits	22
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATX2_HUMAN
NC score	0.053191 (rank : 9)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

AMOT_HUMAN
NC score	0.049396 (rank : 10)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	712	Shared Neighborhood Hits	25
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

SF01_MOUSE
NC score	0.048215 (rank : 11)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

YLPM1_HUMAN
NC score	0.042150 (rank : 12)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	670	Shared Neighborhood Hits	18
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ARI4A_HUMAN
NC score	0.041471 (rank : 13)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	434	Shared Neighborhood Hits	12
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CK024_HUMAN
NC score	0.041436 (rank : 14)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RAD50_HUMAN
NC score	0.039902 (rank : 15)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	1317	Shared Neighborhood Hits	30
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

HCFC1_MOUSE
NC score	0.039693 (rank : 16)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_HUMAN
NC score	0.039334 (rank : 17)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

NP1L3_HUMAN
NC score	0.039294 (rank : 18)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

NUF2_MOUSE
NC score	0.039006 (rank : 19)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	585	Shared Neighborhood Hits	16
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

PCLO_HUMAN
NC score	0.038491 (rank : 20)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	2046	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RAD50_MOUSE
NC score	0.038004 (rank : 21)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	1366	Shared Neighborhood Hits	28
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TLE4_MOUSE
NC score	0.037471 (rank : 22)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	482	Shared Neighborhood Hits	16
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.037461 (rank : 23)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	477	Shared Neighborhood Hits	16
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

PRR12_HUMAN
NC score	0.037167 (rank : 24)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PCLO_MOUSE
NC score	0.036633 (rank : 25)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	2275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NUF2_HUMAN
NC score	0.035630 (rank : 26)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	661	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

SMC2_MOUSE
NC score	0.035351 (rank : 27)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	1131	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

COVA1_MOUSE
NC score	0.035288 (rank : 28)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SMC2_HUMAN
NC score	0.034413 (rank : 29)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SF3A2_HUMAN
NC score	0.034217 (rank : 30)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
NC score	0.033193 (rank : 31)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CLSPN_MOUSE
NC score	0.032406 (rank : 32)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

C8AP2_HUMAN
NC score	0.031378 (rank : 33)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	548	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

SETD2_HUMAN
NC score	0.031207 (rank : 34)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	412	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CKAP4_HUMAN
NC score	0.031192 (rank : 35)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CTGE4_HUMAN
NC score	0.030445 (rank : 36)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	393	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

RTN4_MOUSE
NC score	0.029010 (rank : 37)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

POLH_MOUSE
NC score	0.028867 (rank : 38)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

TCRG1_HUMAN
NC score	0.028475 (rank : 39)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	929	Shared Neighborhood Hits	25
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

HMMR_HUMAN
NC score	0.028215 (rank : 40)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	1082	Shared Neighborhood Hits	24
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MNT_MOUSE
NC score	0.025491 (rank : 41)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	19
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RUFY2_HUMAN
NC score	0.022645 (rank : 42)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	1208	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

IF35_MOUSE
NC score	0.022563 (rank : 43)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

RIN3_MOUSE
NC score	0.022307 (rank : 44)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	239	Shared Neighborhood Hits	10
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

PHF14_MOUSE
NC score	0.022227 (rank : 45)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PIBF1_HUMAN
NC score	0.021444 (rank : 46)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

REST_HUMAN
NC score	0.021032 (rank : 47)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	1605	Shared Neighborhood Hits	30
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

PAR14_MOUSE
NC score	0.020165 (rank : 48)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

G3PT_HUMAN
NC score	0.019825 (rank : 49)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

BPAEA_MOUSE
NC score	0.019381 (rank : 50)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	1480	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

WASIP_MOUSE
NC score	0.018836 (rank : 51)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

TITIN_HUMAN
NC score	0.018682 (rank : 52)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	2923	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PPIG_HUMAN
NC score	0.018383 (rank : 53)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	670	Shared Neighborhood Hits	20
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

BMX_HUMAN
NC score	0.017974 (rank : 54)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	942	Shared Neighborhood Hits	7
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

DIAP2_HUMAN
NC score	0.017672 (rank : 55)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

ITK_HUMAN
NC score	0.017654 (rank : 56)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	1016	Shared Neighborhood Hits	7
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ANR12_HUMAN
NC score	0.016836 (rank : 57)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	1081	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

LIPA3_HUMAN
NC score	0.016044 (rank : 58)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	828	Shared Neighborhood Hits	15
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

ABCF1_HUMAN
NC score	0.015902 (rank : 59)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ROBO3_MOUSE
NC score	0.015876 (rank : 60)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ITK_MOUSE
NC score	0.015730 (rank : 61)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	985	Shared Neighborhood Hits	7
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

ESX1L_HUMAN
NC score	0.015475 (rank : 62)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

DNMBP_MOUSE
NC score	0.014557 (rank : 63)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

BMX_MOUSE
NC score	0.013737 (rank : 64)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	912	Shared Neighborhood Hits	6
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ANX11_HUMAN
NC score	0.013185 (rank : 65)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

PTN23_MOUSE
NC score	0.012267 (rank : 66)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

POGZ_HUMAN
NC score	0.012263 (rank : 67)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

SRCA_HUMAN
NC score	0.011050 (rank : 68)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

ATS12_HUMAN
NC score	0.010393 (rank : 69)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	251	Shared Neighborhood Hits	3
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

TREF1_MOUSE
NC score	0.010329 (rank : 70)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	682	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

HXB2_HUMAN
NC score	0.009070 (rank : 71)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

CSKI2_HUMAN
NC score	0.008847 (rank : 72)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GP126_HUMAN
NC score	0.005808 (rank : 73)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.