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Network neighborhood for query Sequence : SYMPK_MOUSE

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SYMPK_MOUSE
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYMPK_HUMAN
θ value	0 (rank : 1)	NC score	0.978265 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	49
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

IF39_HUMAN
θ value	0.00665767 (rank : 3)	NC score	0.085686 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

LYST_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.085395 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

RAF1_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.039284 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	15
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	0.0113563 (rank : 6)	NC score	0.039469 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	16
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

DNJCD_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.116144 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	O75165, Q6PI82, Q6UJ77, Q6ZSW1, Q6ZUT5, Q86XG3, Q96DC1, Q9BWK9	Gene names	DNAJC13, KIAA0678, RME8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8).

LYST_MOUSE
θ value	0.0431538 (rank : 8)	NC score	0.079248 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

ARAF_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.036853 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	874	Shared Neighborhood Hits	15
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

GRIN1_MOUSE
θ value	0.0736092 (rank : 10)	NC score	0.073642 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BRAF1_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.034010 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	883	Shared Neighborhood Hits	13
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

NAB2_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.098705 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q15742, O76006, Q14797	Gene names	NAB2, MADER
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma- associated delayed early response protein) (Protein MADER).

MTSS1_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.049261 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	592	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CHD4_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.035111 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

MINT_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.047772 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RBFAL_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.064704 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

ARAF_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.034490 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	924	Shared Neighborhood Hits	15
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

CCD21_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.023408 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	1135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MDC1_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.043451 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NAB2_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.086280 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

NOTC2_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.010792 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	1113	Shared Neighborhood Hits	15
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CD2L7_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.020547 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ATM_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.039717 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

CHD3_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.040828 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CN155_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.066347 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IRX6_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.025158 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

RREB1_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.011026 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	879	Shared Neighborhood Hits	14
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

CRSP7_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.042423 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

KI67_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.050804 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	581	Shared Neighborhood Hits	22
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NFH_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.031480 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	2247	Shared Neighborhood Hits	51
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CELR2_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.006266 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

DCR1A_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.042362 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

GRIN1_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.048892 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

M4A12_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.036085 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXJ0, Q8N6L4	Gene names	MS4A12
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 12.

MYO9B_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.012596 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	641	Shared Neighborhood Hits	23
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ORC3_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.061993 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK30	Gene names	Orc3l, Orc3
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

PI3R4_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.037693 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

SON_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.029948 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NEUM_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.052379 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

PAXI_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.018010 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

PHC3_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.047149 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SACS_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.046885 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

SYLM_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.035928 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

FBW1B_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.018549 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

KIFC1_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.009495 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	545	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

PAXI_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.017278 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

PKCB1_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.062512 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	488	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RABE1_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.015358 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	1104	Shared Neighborhood Hits	11
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CHD5_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.033226 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CLAT_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.015577 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	P28329, Q16488, Q9BQ23, Q9BQ35, Q9BQE1	Gene names	CHAT
Domain Architecture
Description	Choline O-acetyltransferase (EC 2.3.1.6) (CHOACTase) (Choline acetylase) (ChAT).

DYHC_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.028026 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	733	Shared Neighborhood Hits	10
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.028086 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	729	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

IPP2_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.030031 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

SACS_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.042772 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

SYNPO_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.034412 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TGON2_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.033749 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	1037	Shared Neighborhood Hits	39
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AP3D1_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.025786 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.024016 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

IF4G1_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.021304 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MAP2_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.019420 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

ORC3_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.049696 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

PCLO_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.022664 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	2275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

STX18_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.037605 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

SYNPO_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.033614 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ZN541_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.021563 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

GON4L_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.020834 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	555	Shared Neighborhood Hits	20
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MARCS_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.039657 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MINT_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.041124 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PIAS1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.020366 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

RAG1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.014160 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBM16_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.034481 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	300	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SRCA_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.020589 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	380	Shared Neighborhood Hits	16
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SYLM_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.030390 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

WNK1_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.015004 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	1179	Shared Neighborhood Hits	23
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ANK1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.004831 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR33_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.019667 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BAT2_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.024753 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	947	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAND2_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.016919 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

FBW1A_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.013772 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

HCN2_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.009575 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

LAP4_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.005568 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

M3K4_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.010486 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	911	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

MBB1A_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.026380 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	233	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

MGR5_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.006633 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MYT1L_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.009925 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NSD1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.022132 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NUAK1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.007700 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	874	Shared Neighborhood Hits	14
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

OGFR_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.050339 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	1582	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PKN3_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.006625 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1009	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RGS3_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.020232 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	1621	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SVIL_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.018416 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TNR21_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.011200 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

UBF1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.020972 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

AP3B1_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.013645 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	302	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CHD8_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.024203 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

GA2L2_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.013170 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

HGS_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.023657 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	589	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

JHD2B_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.012626 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2B_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.012877 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

K1802_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.014938 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	1596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LRRK1_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.011477 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	1267	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LTBP2_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.006006 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOLC1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.034410 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	452	Shared Neighborhood Hits	22
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PIAS1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.016584 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PO2F2_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.005198 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	379	Shared Neighborhood Hits	6
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RP1_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.014689 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

TBCD2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.010235 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ZAR1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.019809 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN688_HUMAN
θ value	8.99809 (rank : 109)	NC score	-0.000717 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	873	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

Hits sorted by NC score

SYMPK_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_HUMAN
NC score	0.978265 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	49
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

DNJCD_HUMAN
NC score	0.116144 (rank : 3)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	O75165, Q6PI82, Q6UJ77, Q6ZSW1, Q6ZUT5, Q86XG3, Q96DC1, Q9BWK9	Gene names	DNAJC13, KIAA0678, RME8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8).

NAB2_HUMAN
NC score	0.098705 (rank : 4)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q15742, O76006, Q14797	Gene names	NAB2, MADER
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma- associated delayed early response protein) (Protein MADER).

NAB2_MOUSE
NC score	0.086280 (rank : 5)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

IF39_HUMAN
NC score	0.085686 (rank : 6)	θ value	0.00665767 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

LYST_HUMAN
NC score	0.085395 (rank : 7)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
NC score	0.079248 (rank : 8)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

GRIN1_MOUSE
NC score	0.073642 (rank : 9)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CN155_HUMAN
NC score	0.066347 (rank : 10)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RBFAL_MOUSE
NC score	0.064704 (rank : 11)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P3B9	Gene names
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

PKCB1_HUMAN
NC score	0.062512 (rank : 12)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	488	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

ORC3_MOUSE
NC score	0.061993 (rank : 13)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK30	Gene names	Orc3l, Orc3
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

NEUM_HUMAN
NC score	0.052379 (rank : 14)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

KI67_HUMAN
NC score	0.050804 (rank : 15)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	581	Shared Neighborhood Hits	22
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

OGFR_HUMAN
NC score	0.050339 (rank : 16)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1582	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ORC3_HUMAN
NC score	0.049696 (rank : 17)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

MTSS1_MOUSE
NC score	0.049261 (rank : 18)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	592	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

GRIN1_HUMAN
NC score	0.048892 (rank : 19)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MINT_HUMAN
NC score	0.047772 (rank : 20)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PHC3_HUMAN
NC score	0.047149 (rank : 21)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SACS_MOUSE
NC score	0.046885 (rank : 22)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

MDC1_MOUSE
NC score	0.043451 (rank : 23)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SACS_HUMAN
NC score	0.042772 (rank : 24)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

CRSP7_HUMAN
NC score	0.042423 (rank : 25)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

DCR1A_MOUSE
NC score	0.042362 (rank : 26)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

MINT_MOUSE
NC score	0.041124 (rank : 27)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CHD3_HUMAN
NC score	0.040828 (rank : 28)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ATM_HUMAN
NC score	0.039717 (rank : 29)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

MARCS_HUMAN
NC score	0.039657 (rank : 30)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

RAF1_MOUSE
NC score	0.039469 (rank : 31)	θ value	0.0113563 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	16
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_HUMAN
NC score	0.039284 (rank : 32)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	15
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

PI3R4_HUMAN
NC score	0.037693 (rank : 33)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

STX18_HUMAN
NC score	0.037605 (rank : 34)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

ARAF_MOUSE
NC score	0.036853 (rank : 35)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	874	Shared Neighborhood Hits	15
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

M4A12_HUMAN
NC score	0.036085 (rank : 36)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXJ0, Q8N6L4	Gene names	MS4A12
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 12.

SYLM_HUMAN
NC score	0.035928 (rank : 37)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

CHD4_MOUSE
NC score	0.035111 (rank : 38)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ARAF_HUMAN
NC score	0.034490 (rank : 39)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	924	Shared Neighborhood Hits	15
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

RBM16_HUMAN
NC score	0.034481 (rank : 40)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	300	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SYNPO_MOUSE
NC score	0.034412 (rank : 41)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

NOLC1_HUMAN
NC score	0.034410 (rank : 42)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	452	Shared Neighborhood Hits	22
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BRAF1_HUMAN
NC score	0.034010 (rank : 43)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	883	Shared Neighborhood Hits	13
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

TGON2_HUMAN
NC score	0.033749 (rank : 44)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	1037	Shared Neighborhood Hits	39
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SYNPO_HUMAN
NC score	0.033614 (rank : 45)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CHD5_HUMAN
NC score	0.033226 (rank : 46)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

NFH_MOUSE
NC score	0.031480 (rank : 47)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	2247	Shared Neighborhood Hits	51
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SYLM_MOUSE
NC score	0.030390 (rank : 48)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

IPP2_MOUSE
NC score	0.030031 (rank : 49)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

SON_HUMAN
NC score	0.029948 (rank : 50)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DYHC_MOUSE
NC score	0.028086 (rank : 51)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	729	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.028026 (rank : 52)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	733	Shared Neighborhood Hits	10
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

MBB1A_MOUSE
NC score	0.026380 (rank : 53)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	233	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

AP3D1_HUMAN
NC score	0.025786 (rank : 54)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

IRX6_HUMAN
NC score	0.025158 (rank : 55)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

BAT2_MOUSE
NC score	0.024753 (rank : 56)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	947	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CHD8_HUMAN
NC score	0.024203 (rank : 57)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

AP3D1_MOUSE
NC score	0.024016 (rank : 58)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

HGS_MOUSE
NC score	0.023657 (rank : 59)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	589	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CCD21_MOUSE
NC score	0.023408 (rank : 60)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	1135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

PCLO_MOUSE
NC score	0.022664 (rank : 61)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	2275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NSD1_HUMAN
NC score	0.022132 (rank : 62)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ZN541_HUMAN
NC score	0.021563 (rank : 63)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

IF4G1_HUMAN
NC score	0.021304 (rank : 64)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

UBF1_HUMAN
NC score	0.020972 (rank : 65)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

GON4L_HUMAN
NC score	0.020834 (rank : 66)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	555	Shared Neighborhood Hits	20
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SRCA_HUMAN
NC score	0.020589 (rank : 67)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	380	Shared Neighborhood Hits	16
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CD2L7_HUMAN
NC score	0.020547 (rank : 68)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	1275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

PIAS1_HUMAN
NC score	0.020366 (rank : 69)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

RGS3_MOUSE
NC score	0.020232 (rank : 70)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	1621	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZAR1_HUMAN
NC score	0.019809 (rank : 71)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ANR33_MOUSE
NC score	0.019667 (rank : 72)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

MAP2_MOUSE
NC score	0.019420 (rank : 73)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

FBW1B_HUMAN
NC score	0.018549 (rank : 74)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

SVIL_HUMAN
NC score	0.018416 (rank : 75)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

PAXI_HUMAN
NC score	0.018010 (rank : 76)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

PAXI_MOUSE
NC score	0.017278 (rank : 77)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

CAND2_MOUSE
NC score	0.016919 (rank : 78)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

PIAS1_MOUSE
NC score	0.016584 (rank : 79)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

CLAT_HUMAN
NC score	0.015577 (rank : 80)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	P28329, Q16488, Q9BQ23, Q9BQ35, Q9BQE1	Gene names	CHAT
Domain Architecture
Description	Choline O-acetyltransferase (EC 2.3.1.6) (CHOACTase) (Choline acetylase) (ChAT).

RABE1_HUMAN
NC score	0.015358 (rank : 81)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	1104	Shared Neighborhood Hits	11
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

WNK1_MOUSE
NC score	0.015004 (rank : 82)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	1179	Shared Neighborhood Hits	23
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

K1802_MOUSE
NC score	0.014938 (rank : 83)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	1596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RP1_MOUSE
NC score	0.014689 (rank : 84)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

RAG1_MOUSE
NC score	0.014160 (rank : 85)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

FBW1A_HUMAN
NC score	0.013772 (rank : 86)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

AP3B1_MOUSE
NC score	0.013645 (rank : 87)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	302	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

GA2L2_HUMAN
NC score	0.013170 (rank : 88)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

JHD2B_MOUSE
NC score	0.012877 (rank : 89)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2B_HUMAN
NC score	0.012626 (rank : 90)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

MYO9B_HUMAN
NC score	0.012596 (rank : 91)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	641	Shared Neighborhood Hits	23
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

LRRK1_MOUSE
NC score	0.011477 (rank : 92)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	1267	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TNR21_HUMAN
NC score	0.011200 (rank : 93)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

RREB1_HUMAN
NC score	0.011026 (rank : 94)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	879	Shared Neighborhood Hits	14
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

NOTC2_HUMAN
NC score	0.010792 (rank : 95)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	1113	Shared Neighborhood Hits	15
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

M3K4_HUMAN
NC score	0.010486 (rank : 96)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	911	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

TBCD2_HUMAN
NC score	0.010235 (rank : 97)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	419	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

MYT1L_HUMAN
NC score	0.009925 (rank : 98)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

HCN2_MOUSE
NC score	0.009575 (rank : 99)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

KIFC1_HUMAN
NC score	0.009495 (rank : 100)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	545	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

NUAK1_HUMAN
NC score	0.007700 (rank : 101)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	874	Shared Neighborhood Hits	14
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

MGR5_HUMAN
NC score	0.006633 (rank : 102)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

PKN3_MOUSE
NC score	0.006625 (rank : 103)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	1009	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

CELR2_HUMAN
NC score	0.006266 (rank : 104)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LTBP2_MOUSE
NC score	0.006006 (rank : 105)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAP4_HUMAN
NC score	0.005568 (rank : 106)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PO2F2_HUMAN
NC score	0.005198 (rank : 107)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	379	Shared Neighborhood Hits	6
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

ANK1_HUMAN
NC score	0.004831 (rank : 108)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ZN688_HUMAN
NC score	-0.000717 (rank : 109)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	873	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.