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Network neighborhood for query Sequence : CCM2_HUMAN

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CCM2_HUMAN
SwissProt Accessions	Q9BSQ5, Q71RE5, Q8TAT4	Gene names	CCM2, C7orf22
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations 2 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CCM2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BSQ5, Q71RE5, Q8TAT4	Gene names	CCM2, C7orf22
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations 2 protein).

CCM2_MOUSE
θ value	0 (rank : 2)	NC score	0.999195 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

CT160_HUMAN
θ value	3.73686e-38 (rank : 3)	NC score	0.838808 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUG4, Q5JYR9, Q8N5F1, Q8N6G8, Q96MD5	Gene names	C20orf160
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160.

CT160_MOUSE
θ value	2.26708e-35 (rank : 4)	NC score	0.870524 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCC6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160 homolog.

SYNE1_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.012416 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1484	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MLH1_HUMAN
θ value	3.0926 (rank : 6)	NC score	0.042840 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

ACHA3_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.007461 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	P32297, Q15823, Q96RH3, Q99553, Q9BQ93	Gene names	CHRNA3, NACHRA3
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-3 precursor.

CD2L7_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.002526 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	1275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ACHA3_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.006957 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4G9, Q8BV44	Gene names	Chrna3
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit alpha-3 precursor.

BIRC6_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.017187 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

Hits sorted by NC score

CCM2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BSQ5, Q71RE5, Q8TAT4	Gene names	CCM2, C7orf22
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations 2 protein).

CCM2_MOUSE
NC score	0.999195 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

CT160_MOUSE
NC score	0.870524 (rank : 3)	θ value	2.26708e-35 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCC6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160 homolog.

CT160_HUMAN
NC score	0.838808 (rank : 4)	θ value	3.73686e-38 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUG4, Q5JYR9, Q8N5F1, Q8N6G8, Q96MD5	Gene names	C20orf160
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160.

MLH1_HUMAN
NC score	0.042840 (rank : 5)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

BIRC6_HUMAN
NC score	0.017187 (rank : 6)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

SYNE1_HUMAN
NC score	0.012416 (rank : 7)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	1484	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ACHA3_HUMAN
NC score	0.007461 (rank : 8)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	P32297, Q15823, Q96RH3, Q99553, Q9BQ93	Gene names	CHRNA3, NACHRA3
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-3 precursor.

ACHA3_MOUSE
NC score	0.006957 (rank : 9)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4G9, Q8BV44	Gene names	Chrna3
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit alpha-3 precursor.

CD2L7_HUMAN
NC score	0.002526 (rank : 10)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	1275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).