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Network neighborhood for query Sequence : UB2E3_HUMAN

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UB2E3_HUMAN
SwissProt Accessions	Q969T4, Q5U0R7, Q7Z4W4	Gene names	UBE2E3, UBCE4, UBCH9
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcH9) (UbcM2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UB2E1_MOUSE
θ value	2.82168e-86 (rank : 1)	NC score	0.997922 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	55
SwissProt Accessions	P52482	Gene names	Ube2e1, Ubce5, Ubcm3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcM3).

UB2E3_HUMAN
θ value	2.82168e-86 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	Q969T4, Q5U0R7, Q7Z4W4	Gene names	UBE2E3, UBCE4, UBCH9
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcH9) (UbcM2).

UB2E3_MOUSE
θ value	2.82168e-86 (rank : 3)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P52483, O09180, Q3TI00, Q91X63	Gene names	Ube2e3, Ubce4, Ubcm2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcM2).

UB2E1_HUMAN
θ value	2.23575e-83 (rank : 4)	NC score	0.997961 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	55
SwissProt Accessions	P51965	Gene names	UBE2E1, UBCH6
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcH6).

UB2E2_MOUSE
θ value	3.56943e-81 (rank : 5)	NC score	0.999481 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

UB2E2_HUMAN
θ value	1.03855e-80 (rank : 6)	NC score	0.999567 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

UB2D1_HUMAN
θ value	1.32293e-51 (rank : 7)	NC score	0.985766 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P51668	Gene names	UBE2D1, UBCH5, UBCH5A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (UbcH5) (Ubiquitin- conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D1_MOUSE
θ value	1.32293e-51 (rank : 8)	NC score	0.985766 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61080	Gene names	Ube2d1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D2_HUMAN
θ value	1.32293e-51 (rank : 9)	NC score	0.985068 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P62837, P51669	Gene names	UBE2D2, UBC4, UBCH5B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D2_MOUSE
θ value	1.32293e-51 (rank : 10)	NC score	0.985068 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P62838, P51669	Gene names	Ube2d2, Ubc4
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D3_HUMAN
θ value	1.72781e-51 (rank : 11)	NC score	0.985445 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P61077, P47986, Q6IB88, Q6NXS4	Gene names	UBE2D3, UBCH5C
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2D3_MOUSE
θ value	1.72781e-51 (rank : 12)	NC score	0.985445 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P61079	Gene names	Ube2d3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UBE2N_HUMAN
θ value	3.74554e-30 (rank : 13)	NC score	0.964977 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61088, Q16781	Gene names	UBE2N, BLU
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2N_MOUSE
θ value	3.74554e-30 (rank : 14)	NC score	0.964977 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61089, Q16781, Q6ZWZ0, Q9DAJ6	Gene names	Ube2n, Blu
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2T_MOUSE
θ value	1.73987e-27 (rank : 15)	NC score	0.955777 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQ37	Gene names	Ube2t
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBE2T_HUMAN
θ value	1.47289e-26 (rank : 16)	NC score	0.953601 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NPD8	Gene names	UBE2T
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBE2B_HUMAN
θ value	4.28545e-26 (rank : 17)	NC score	0.941347 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P63146, P23567, Q4PJ15, Q9D0J6	Gene names	UBE2B, RAD6B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (hHR6B) (E2-17 kDa).

UBE2B_MOUSE
θ value	4.28545e-26 (rank : 18)	NC score	0.941347 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P63147, P23567, Q3UGS2, Q9D0J6	Gene names	Ube2b, Rad6b
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (E214K).

UBE2A_HUMAN
θ value	1.62847e-25 (rank : 19)	NC score	0.940125 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P49459, Q4TTG1, Q96FX4	Gene names	UBE2A, RAD6A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (hHR6A).

UBE2A_MOUSE
θ value	1.62847e-25 (rank : 20)	NC score	0.940125 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z255	Gene names	Ube2a, Rad6a
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (mHR6A).

UBC1_HUMAN
θ value	1.5242e-23 (rank : 21)	NC score	0.945913 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	P61086, O54806, P27924, Q16721, Q9CVV9, Q9Y2D3	Gene names	HIP2, LIG
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBC1_MOUSE
θ value	1.5242e-23 (rank : 22)	NC score	0.945913 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	P61087, O54806, P27924, Q16721, Q9CVV9	Gene names	Hip2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBE2C_HUMAN
θ value	2.43343e-21 (rank : 23)	NC score	0.935844 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	O00762	Gene names	UBE2C, UBCH10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UB2L3_HUMAN
θ value	3.17815e-21 (rank : 24)	NC score	0.933880 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
θ value	3.17815e-21 (rank : 25)	NC score	0.933880 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

UBE2C_MOUSE
θ value	5.42112e-21 (rank : 26)	NC score	0.935965 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D1C1, Q3TUJ0	Gene names	Ube2c, Ubch10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UB2G1_HUMAN
θ value	1.2077e-20 (rank : 27)	NC score	0.927953 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62253, Q99462	Gene names	UBE2G1, UBE2G
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UB2G1_MOUSE
θ value	1.2077e-20 (rank : 28)	NC score	0.927953 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62254, Q99462	Gene names	Ube2g1, Ube2g
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UB2G2_HUMAN
θ value	5.99374e-20 (rank : 29)	NC score	0.924605 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P60604, P56554	Gene names	UBE2G2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UB2G2_MOUSE
θ value	5.99374e-20 (rank : 30)	NC score	0.924605 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P60605, P56554	Gene names	Ube2g2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UBC9_HUMAN
θ value	1.33526e-19 (rank : 31)	NC score	0.928966 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	P63279, P50550, Q15698, Q86VB3	Gene names	UBE2I, UBC9, UBCE9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (p18).

UBC9_MOUSE
θ value	1.33526e-19 (rank : 32)	NC score	0.928966 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	P63280, P50550, Q15698, Q86VB3	Gene names	Ube2i, Ubc9, Ubce9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (mUBC9).

UBE2S_HUMAN
θ value	5.07402e-19 (rank : 33)	NC score	0.929155 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	Q16763, Q9BTC1	Gene names	UBE2S, E2EPF
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UBE2S_MOUSE
θ value	8.65492e-19 (rank : 34)	NC score	0.927490 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q921J4, Q3U4V7	Gene names	Ube2s, E2epf
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UBE2W_HUMAN
θ value	1.47631e-18 (rank : 35)	NC score	0.916612 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q96B02, Q9H823, Q9HAG6, Q9NV07	Gene names	UBE2W
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UBE2W_MOUSE
θ value	1.47631e-18 (rank : 36)	NC score	0.916779 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VDW4, Q9D5H3	Gene names	Ube2w
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UBC12_HUMAN
θ value	8.10077e-17 (rank : 37)	NC score	0.896196 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61081, O76069, Q8VC50	Gene names	UBE2M, UBC12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBC12_MOUSE
θ value	8.10077e-17 (rank : 38)	NC score	0.896196 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61082, O76069, Q8VC50	Gene names	Ube2m, Ubc-rs2, Ubc12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBE2H_HUMAN
θ value	3.40345e-15 (rank : 39)	NC score	0.911080 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62256, P37286	Gene names	UBE2H
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UbcH2) (E2-20K).

UBE2H_MOUSE
θ value	3.40345e-15 (rank : 40)	NC score	0.911080 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62257, P37286	Gene names	Ube2h
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UBCH2) (E2-20K).

UB2L6_HUMAN
θ value	1.29331e-14 (rank : 41)	NC score	0.915447 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	O14933, Q9UEZ0	Gene names	UBE2L6, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcH8) (Retinoic acid- induced gene B protein) (RIG-B).

UB2R1_HUMAN
θ value	3.76295e-14 (rank : 42)	NC score	0.889745 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	P49427	Gene names	CDC34, UBE2R1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2R1_MOUSE
θ value	3.76295e-14 (rank : 43)	NC score	0.889944 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFI2, Q505K8	Gene names	Cdc34
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2J2_HUMAN
θ value	8.38298e-14 (rank : 44)	NC score	0.816182 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N2K1, Q96N26, Q96T84	Gene names	UBE2J2, NCUBE2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J2_MOUSE
θ value	1.86753e-13 (rank : 45)	NC score	0.818780 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	55	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P073, Q8C6A1, Q91Y64, Q9CWY5, Q9DC18, Q9QX58	Gene names	Ube2j2, Ncube2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J1_HUMAN
θ value	1.58096e-12 (rank : 46)	NC score	0.785995 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

UB2J1_MOUSE
θ value	1.58096e-12 (rank : 47)	NC score	0.785215 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

UB2L6_MOUSE
θ value	3.52202e-12 (rank : 48)	NC score	0.896642 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

UBE2U_HUMAN
θ value	1.38499e-08 (rank : 49)	NC score	0.863793 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VVX9, Q8N1D4	Gene names	UBE2U
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 U (EC 6.3.2.19) (Ubiquitin-protein ligase U) (Ubiquitin carrier protein U).

BIRC6_HUMAN
θ value	3.19293e-05 (rank : 50)	NC score	0.551164 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

UB2V1_HUMAN
θ value	0.000461057 (rank : 51)	NC score	0.512432 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q13404, Q13403, Q13532, Q96H34, Q9GZT0, Q9GZW1, Q9H4J3, Q9H4J4, Q9UKL1, Q9UM48, Q9UM49, Q9UM50	Gene names	UBE2V1, CROC1, UBE2V, UEV1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (Ubiquitin- conjugating enzyme variant Kua) (TRAF6-regulated IKK activator 1 beta Uev1A).

UB2V1_MOUSE
θ value	0.000786445 (rank : 52)	NC score	0.507421 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZY3, Q8VEB5, Q9ERI7	Gene names	Ube2v1, Croc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1).

UB2V2_MOUSE
θ value	0.00134147 (rank : 53)	NC score	0.511037 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D2M8, Q8BGH6, Q8CE99, Q8K2V7, Q9CYD7, Q9ERI8	Gene names	Ube2v2, Mms2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (Ubc-like protein MMS2).

UB2V2_HUMAN
θ value	0.00390308 (rank : 54)	NC score	0.509703 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	51	Shared Neighborhood Hits	49
SwissProt Accessions	Q15819	Gene names	UBE2V2, MMS2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) (Enterocyte differentiation-associated factor EDAF-1) (Enterocyte differentiation- promoting factor) (EDPF-1) (Vitamin D3-inducible protein) (DDVit 1).

UB2Q1_HUMAN
θ value	0.00665767 (rank : 55)	NC score	0.155859 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7E8, Q3B841, Q5I0X2, Q6IS04, Q6P7P2, Q96MV4, Q9BVX5, Q9UGL6	Gene names	UBE2Q1, NICE5, UBE2Q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1) (Protein NICE-5).

UB2Q1_MOUSE
θ value	0.00665767 (rank : 56)	NC score	0.155857 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TSS2, Q3UIY3, Q6P913, Q80UT5, Q8K2T0, Q9D7E1	Gene names	Ube2q1, Ube2q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1).

UB2Q2_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.132253 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	40	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVN8, Q8N4G6, Q96J08	Gene names	UBE2Q2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2).

UB2Q2_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.121812 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2Z8, Q3UBX3, Q3V3A5, Q8BUN2, Q8BVX5	Gene names	Ube2q2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2).

MDN1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.011457 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	662	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYCB2_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.005071 (rank : 63)
Query Neighborhood Hits	62	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

THAP4_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.007952 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

ERBB2_MOUSE
θ value	8.99809 (rank : 62)	NC score	-0.003452 (rank : 64)
Query Neighborhood Hits	62	Target Neighborhood Hits	918	Shared Neighborhood Hits	7
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FTS1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.245171 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H8T0	Gene names	FTS
Domain Architecture	No domain graphic available
Description	Fused toes protein homolog (Ft1).

FTS1_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.247993 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

Hits sorted by NC score

UB2E3_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.82168e-86 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	Q969T4, Q5U0R7, Q7Z4W4	Gene names	UBE2E3, UBCE4, UBCH9
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcH9) (UbcM2).

UB2E3_MOUSE
NC score	0.999962 (rank : 2)	θ value	2.82168e-86 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P52483, O09180, Q3TI00, Q91X63	Gene names	Ube2e3, Ubce4, Ubcm2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcM2).

UB2E2_HUMAN
NC score	0.999567 (rank : 3)	θ value	1.03855e-80 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

UB2E2_MOUSE
NC score	0.999481 (rank : 4)	θ value	3.56943e-81 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

UB2E1_HUMAN
NC score	0.997961 (rank : 5)	θ value	2.23575e-83 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	55
SwissProt Accessions	P51965	Gene names	UBE2E1, UBCH6
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcH6).

UB2E1_MOUSE
NC score	0.997922 (rank : 6)	θ value	2.82168e-86 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	55
SwissProt Accessions	P52482	Gene names	Ube2e1, Ubce5, Ubcm3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcM3).

UB2D1_HUMAN
NC score	0.985766 (rank : 7)	θ value	1.32293e-51 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P51668	Gene names	UBE2D1, UBCH5, UBCH5A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (UbcH5) (Ubiquitin- conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D1_MOUSE
NC score	0.985766 (rank : 8)	θ value	1.32293e-51 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61080	Gene names	Ube2d1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D3_HUMAN
NC score	0.985445 (rank : 9)	θ value	1.72781e-51 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P61077, P47986, Q6IB88, Q6NXS4	Gene names	UBE2D3, UBCH5C
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2D3_MOUSE
NC score	0.985445 (rank : 10)	θ value	1.72781e-51 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P61079	Gene names	Ube2d3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2D2_HUMAN
NC score	0.985068 (rank : 11)	θ value	1.32293e-51 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P62837, P51669	Gene names	UBE2D2, UBC4, UBCH5B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D2_MOUSE
NC score	0.985068 (rank : 12)	θ value	1.32293e-51 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	P62838, P51669	Gene names	Ube2d2, Ubc4
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UBE2N_HUMAN
NC score	0.964977 (rank : 13)	θ value	3.74554e-30 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61088, Q16781	Gene names	UBE2N, BLU
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2N_MOUSE
NC score	0.964977 (rank : 14)	θ value	3.74554e-30 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	54
SwissProt Accessions	P61089, Q16781, Q6ZWZ0, Q9DAJ6	Gene names	Ube2n, Blu
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2T_MOUSE
NC score	0.955777 (rank : 15)	θ value	1.73987e-27 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQ37	Gene names	Ube2t
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBE2T_HUMAN
NC score	0.953601 (rank : 16)	θ value	1.47289e-26 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NPD8	Gene names	UBE2T
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBC1_HUMAN
NC score	0.945913 (rank : 17)	θ value	1.5242e-23 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	P61086, O54806, P27924, Q16721, Q9CVV9, Q9Y2D3	Gene names	HIP2, LIG
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBC1_MOUSE
NC score	0.945913 (rank : 18)	θ value	1.5242e-23 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	65	Shared Neighborhood Hits	58
SwissProt Accessions	P61087, O54806, P27924, Q16721, Q9CVV9	Gene names	Hip2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBE2B_HUMAN
NC score	0.941347 (rank : 19)	θ value	4.28545e-26 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P63146, P23567, Q4PJ15, Q9D0J6	Gene names	UBE2B, RAD6B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (hHR6B) (E2-17 kDa).

UBE2B_MOUSE
NC score	0.941347 (rank : 20)	θ value	4.28545e-26 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P63147, P23567, Q3UGS2, Q9D0J6	Gene names	Ube2b, Rad6b
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (E214K).

UBE2A_HUMAN
NC score	0.940125 (rank : 21)	θ value	1.62847e-25 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P49459, Q4TTG1, Q96FX4	Gene names	UBE2A, RAD6A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (hHR6A).

UBE2A_MOUSE
NC score	0.940125 (rank : 22)	θ value	1.62847e-25 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z255	Gene names	Ube2a, Rad6a
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (mHR6A).

UBE2C_MOUSE
NC score	0.935965 (rank : 23)	θ value	5.42112e-21 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D1C1, Q3TUJ0	Gene names	Ube2c, Ubch10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UBE2C_HUMAN
NC score	0.935844 (rank : 24)	θ value	2.43343e-21 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	O00762	Gene names	UBE2C, UBCH10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UB2L3_HUMAN
NC score	0.933880 (rank : 25)	θ value	3.17815e-21 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
NC score	0.933880 (rank : 26)	θ value	3.17815e-21 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

UBE2S_HUMAN
NC score	0.929155 (rank : 27)	θ value	5.07402e-19 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	Q16763, Q9BTC1	Gene names	UBE2S, E2EPF
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UBC9_HUMAN
NC score	0.928966 (rank : 28)	θ value	1.33526e-19 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	P63279, P50550, Q15698, Q86VB3	Gene names	UBE2I, UBC9, UBCE9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (p18).

UBC9_MOUSE
NC score	0.928966 (rank : 29)	θ value	1.33526e-19 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	P63280, P50550, Q15698, Q86VB3	Gene names	Ube2i, Ubc9, Ubce9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (mUBC9).

UB2G1_HUMAN
NC score	0.927953 (rank : 30)	θ value	1.2077e-20 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62253, Q99462	Gene names	UBE2G1, UBE2G
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UB2G1_MOUSE
NC score	0.927953 (rank : 31)	θ value	1.2077e-20 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62254, Q99462	Gene names	Ube2g1, Ube2g
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UBE2S_MOUSE
NC score	0.927490 (rank : 32)	θ value	8.65492e-19 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q921J4, Q3U4V7	Gene names	Ube2s, E2epf
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UB2G2_HUMAN
NC score	0.924605 (rank : 33)	θ value	5.99374e-20 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P60604, P56554	Gene names	UBE2G2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UB2G2_MOUSE
NC score	0.924605 (rank : 34)	θ value	5.99374e-20 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P60605, P56554	Gene names	Ube2g2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UBE2W_MOUSE
NC score	0.916779 (rank : 35)	θ value	1.47631e-18 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VDW4, Q9D5H3	Gene names	Ube2w
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UBE2W_HUMAN
NC score	0.916612 (rank : 36)	θ value	1.47631e-18 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q96B02, Q9H823, Q9HAG6, Q9NV07	Gene names	UBE2W
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UB2L6_HUMAN
NC score	0.915447 (rank : 37)	θ value	1.29331e-14 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	O14933, Q9UEZ0	Gene names	UBE2L6, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcH8) (Retinoic acid- induced gene B protein) (RIG-B).

UBE2H_HUMAN
NC score	0.911080 (rank : 38)	θ value	3.40345e-15 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62256, P37286	Gene names	UBE2H
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UbcH2) (E2-20K).

UBE2H_MOUSE
NC score	0.911080 (rank : 39)	θ value	3.40345e-15 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	56	Shared Neighborhood Hits	54
SwissProt Accessions	P62257, P37286	Gene names	Ube2h
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UBCH2) (E2-20K).

UB2L6_MOUSE
NC score	0.896642 (rank : 40)	θ value	3.52202e-12 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

UBC12_HUMAN
NC score	0.896196 (rank : 41)	θ value	8.10077e-17 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61081, O76069, Q8VC50	Gene names	UBE2M, UBC12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBC12_MOUSE
NC score	0.896196 (rank : 42)	θ value	8.10077e-17 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61082, O76069, Q8VC50	Gene names	Ube2m, Ubc-rs2, Ubc12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UB2R1_MOUSE
NC score	0.889944 (rank : 43)	θ value	3.76295e-14 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFI2, Q505K8	Gene names	Cdc34
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2R1_HUMAN
NC score	0.889745 (rank : 44)	θ value	3.76295e-14 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	P49427	Gene names	CDC34, UBE2R1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UBE2U_HUMAN
NC score	0.863793 (rank : 45)	θ value	1.38499e-08 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VVX9, Q8N1D4	Gene names	UBE2U
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 U (EC 6.3.2.19) (Ubiquitin-protein ligase U) (Ubiquitin carrier protein U).

UB2J2_MOUSE
NC score	0.818780 (rank : 46)	θ value	1.86753e-13 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	55	Shared Neighborhood Hits	50
SwissProt Accessions	Q6P073, Q8C6A1, Q91Y64, Q9CWY5, Q9DC18, Q9QX58	Gene names	Ube2j2, Ncube2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J2_HUMAN
NC score	0.816182 (rank : 47)	θ value	8.38298e-14 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N2K1, Q96N26, Q96T84	Gene names	UBE2J2, NCUBE2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J1_HUMAN
NC score	0.785995 (rank : 48)	θ value	1.58096e-12 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

UB2J1_MOUSE
NC score	0.785215 (rank : 49)	θ value	1.58096e-12 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

BIRC6_HUMAN
NC score	0.551164 (rank : 50)	θ value	3.19293e-05 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

UB2V1_HUMAN
NC score	0.512432 (rank : 51)	θ value	0.000461057 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q13404, Q13403, Q13532, Q96H34, Q9GZT0, Q9GZW1, Q9H4J3, Q9H4J4, Q9UKL1, Q9UM48, Q9UM49, Q9UM50	Gene names	UBE2V1, CROC1, UBE2V, UEV1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (Ubiquitin- conjugating enzyme variant Kua) (TRAF6-regulated IKK activator 1 beta Uev1A).

UB2V2_MOUSE
NC score	0.511037 (rank : 52)	θ value	0.00134147 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D2M8, Q8BGH6, Q8CE99, Q8K2V7, Q9CYD7, Q9ERI8	Gene names	Ube2v2, Mms2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (Ubc-like protein MMS2).

UB2V2_HUMAN
NC score	0.509703 (rank : 53)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	51	Shared Neighborhood Hits	49
SwissProt Accessions	Q15819	Gene names	UBE2V2, MMS2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) (Enterocyte differentiation-associated factor EDAF-1) (Enterocyte differentiation- promoting factor) (EDPF-1) (Vitamin D3-inducible protein) (DDVit 1).

UB2V1_MOUSE
NC score	0.507421 (rank : 54)	θ value	0.000786445 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZY3, Q8VEB5, Q9ERI7	Gene names	Ube2v1, Croc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1).

FTS1_MOUSE
NC score	0.247993 (rank : 55)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

FTS1_HUMAN
NC score	0.245171 (rank : 56)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	62	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H8T0	Gene names	FTS
Domain Architecture	No domain graphic available
Description	Fused toes protein homolog (Ft1).

UB2Q1_HUMAN
NC score	0.155859 (rank : 57)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7E8, Q3B841, Q5I0X2, Q6IS04, Q6P7P2, Q96MV4, Q9BVX5, Q9UGL6	Gene names	UBE2Q1, NICE5, UBE2Q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1) (Protein NICE-5).

UB2Q1_MOUSE
NC score	0.155857 (rank : 58)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TSS2, Q3UIY3, Q6P913, Q80UT5, Q8K2T0, Q9D7E1	Gene names	Ube2q1, Ube2q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1).

UB2Q2_HUMAN
NC score	0.132253 (rank : 59)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	40	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WVN8, Q8N4G6, Q96J08	Gene names	UBE2Q2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2).

UB2Q2_MOUSE
NC score	0.121812 (rank : 60)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2Z8, Q3UBX3, Q3V3A5, Q8BUN2, Q8BVX5	Gene names	Ube2q2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2).

MDN1_HUMAN
NC score	0.011457 (rank : 61)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	662	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

THAP4_MOUSE
NC score	0.007952 (rank : 62)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

MYCB2_MOUSE
NC score	0.005071 (rank : 63)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ERBB2_MOUSE
NC score	-0.003452 (rank : 64)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	918	Shared Neighborhood Hits	7
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).