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Network neighborhood for query Sequence : RCOR1_HUMAN

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RCOR1_HUMAN
SwissProt Accessions	Q9UKL0, Q15044, Q6P2I9, Q86VG5	Gene names	RCOR1, KIAA0071, RCOR
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RCOR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKL0, Q15044, Q6P2I9, Q86VG5	Gene names	RCOR1, KIAA0071, RCOR
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR1_MOUSE
θ value	0 (rank : 2)	NC score	0.997288 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFE3, Q3V092, Q8BK28, Q8CHI2	Gene names	Rcor1, D12Wsu95e, Kiaa0071
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR3_HUMAN
θ value	1.33454e-136 (rank : 3)	NC score	0.966469 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RCOR2_MOUSE
θ value	3.31004e-111 (rank : 4)	NC score	0.962815 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

RCOR2_HUMAN
θ value	4.77967e-110 (rank : 5)	NC score	0.963526 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR3_MOUSE
θ value	6.0463e-105 (rank : 6)	NC score	0.954482 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

NCOR2_HUMAN
θ value	1.92812e-18 (rank : 7)	NC score	0.488680 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	870	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	1.80466e-16 (rank : 8)	NC score	0.478294 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	790	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NCOR1_MOUSE
θ value	6.85773e-16 (rank : 9)	NC score	0.489453 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	521	Shared Neighborhood Hits	26
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

MTA3_MOUSE
θ value	1.52774e-15 (rank : 10)	NC score	0.534526 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q924K8, Q8VC18	Gene names	Mta3
Domain Architecture
Description	Metastasis-associated protein MTA3.

NCOR1_HUMAN
θ value	1.52774e-15 (rank : 11)	NC score	0.483127 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

MTA2_HUMAN
θ value	7.09661e-13 (rank : 12)	NC score	0.525135 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

MTA2_MOUSE
θ value	1.2105e-12 (rank : 13)	NC score	0.521717 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R190, Q3TVT8	Gene names	Mta2, Mta1l1
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1).

MTA3_HUMAN
θ value	6.00763e-12 (rank : 14)	NC score	0.522920 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BTC8, Q9NSP2, Q9ULF4	Gene names	MTA3, KIAA1266
Domain Architecture
Description	Metastasis-associated protein MTA3.

MTA1_HUMAN
θ value	6.64225e-11 (rank : 15)	NC score	0.494881 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q13330, Q8NFI8, Q96GI8	Gene names	MTA1
Domain Architecture
Description	Metastasis-associated protein MTA1.

MTA1_MOUSE
θ value	4.30538e-10 (rank : 16)	NC score	0.490252 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K4B0, Q80UI1, Q8K4D4, Q924K9	Gene names	Mta1
Domain Architecture
Description	Metastasis-associated protein MTA1.

ZN541_HUMAN
θ value	1.80886e-08 (rank : 17)	NC score	0.521040 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

TREF1_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.375363 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	682	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

TREF1_HUMAN
θ value	1.53129e-07 (rank : 19)	NC score	0.378194 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	651	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

RERE_MOUSE
θ value	2.88788e-06 (rank : 20)	NC score	0.336555 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RERE_HUMAN
θ value	4.92598e-06 (rank : 21)	NC score	0.334064 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MIER1_MOUSE
θ value	2.44474e-05 (rank : 22)	NC score	0.462567 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

MIER1_HUMAN
θ value	4.1701e-05 (rank : 23)	NC score	0.458124 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

MYSM1_HUMAN
θ value	0.00228821 (rank : 24)	NC score	0.244039 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MYSM1_MOUSE
θ value	0.00228821 (rank : 25)	NC score	0.244799 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NIN_HUMAN
θ value	0.00298849 (rank : 26)	NC score	0.041628 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	1416	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

MDC1_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.056732 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	1446	Shared Neighborhood Hits	19
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TRAIP_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.044637 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	745	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MYH3_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.023752 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	1660	Shared Neighborhood Hits	26
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PNMA1_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.032315 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8ND90, O95144, Q8NG07	Gene names	PNMA1, MA1
Domain Architecture	No domain graphic available
Description	Paraneoplastic antigen Ma1 (Neuron- and testis-specific protein 1) (37 kDa neuronal protein).

TPR_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.025767 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CUTL2_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.035428 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	24
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

KCD18_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.025648 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

RHG12_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.024674 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MYH7_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.020675 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	1559	Shared Neighborhood Hits	23
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RHG12_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.023474 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GSTK1_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.039007 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q3, Q9P1S4	Gene names	GSTK1
Domain Architecture
Description	Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (Glutathione S-transferase subunit 13) (GST class-kappa) (GSTK1-1) (hGSTK1).

MD1L1_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.031097 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	893	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

SPTA1_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.017247 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	675	Shared Neighborhood Hits	19
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

PLCB1_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.018604 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	614	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

JHD1B_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.010347 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MYH11_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.017807 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	1806	Shared Neighborhood Hits	26
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NUPL_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.012256 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

RAD18_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.017419 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRAIP_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.032561 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	780	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BIRC6_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.017623 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

MYH11_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.020103 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	1777	Shared Neighborhood Hits	26
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH4_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.018868 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	1476	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.020083 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	1600	Shared Neighborhood Hits	25
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NTRK2_HUMAN
θ value	5.27518 (rank : 50)	NC score	-0.001419 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	1081	Shared Neighborhood Hits	3
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	5.27518 (rank : 51)	NC score	-0.001439 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	1088	Shared Neighborhood Hits	3
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

CKAP4_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.015859 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	596	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYH8_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.019403 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	1610	Shared Neighborhood Hits	27
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SMC2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.019134 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

AP3D1_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.006058 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

CCD45_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.016060 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	663	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

FILA_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.015208 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	685	Shared Neighborhood Hits	9
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GRIN1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.017855 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	681	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NEST_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.017496 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	1305	Shared Neighborhood Hits	27
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PRDM2_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.006110 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RBP1_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.013850 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	521	Shared Neighborhood Hits	21
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

ATN1_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.065008 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	676	Shared Neighborhood Hits	12
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CJ108_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.054557 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

DCP1A_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.056555 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

FA47B_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.053790 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GA2L2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.054422 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

MDC1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.056954 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	998	Shared Neighborhood Hits	17
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SON_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.054860 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

Hits sorted by NC score

RCOR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKL0, Q15044, Q6P2I9, Q86VG5	Gene names	RCOR1, KIAA0071, RCOR
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR1_MOUSE
NC score	0.997288 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFE3, Q3V092, Q8BK28, Q8CHI2	Gene names	Rcor1, D12Wsu95e, Kiaa0071
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR3_HUMAN
NC score	0.966469 (rank : 3)	θ value	1.33454e-136 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RCOR2_HUMAN
NC score	0.963526 (rank : 4)	θ value	4.77967e-110 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
NC score	0.962815 (rank : 5)	θ value	3.31004e-111 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

RCOR3_MOUSE
NC score	0.954482 (rank : 6)	θ value	6.0463e-105 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

MTA3_MOUSE
NC score	0.534526 (rank : 7)	θ value	1.52774e-15 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q924K8, Q8VC18	Gene names	Mta3
Domain Architecture
Description	Metastasis-associated protein MTA3.

MTA2_HUMAN
NC score	0.525135 (rank : 8)	θ value	7.09661e-13 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

MTA3_HUMAN
NC score	0.522920 (rank : 9)	θ value	6.00763e-12 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BTC8, Q9NSP2, Q9ULF4	Gene names	MTA3, KIAA1266
Domain Architecture
Description	Metastasis-associated protein MTA3.

MTA2_MOUSE
NC score	0.521717 (rank : 10)	θ value	1.2105e-12 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R190, Q3TVT8	Gene names	Mta2, Mta1l1
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1).

ZN541_HUMAN
NC score	0.521040 (rank : 11)	θ value	1.80886e-08 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

MTA1_HUMAN
NC score	0.494881 (rank : 12)	θ value	6.64225e-11 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q13330, Q8NFI8, Q96GI8	Gene names	MTA1
Domain Architecture
Description	Metastasis-associated protein MTA1.

MTA1_MOUSE
NC score	0.490252 (rank : 13)	θ value	4.30538e-10 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K4B0, Q80UI1, Q8K4D4, Q924K9	Gene names	Mta1
Domain Architecture
Description	Metastasis-associated protein MTA1.

NCOR1_MOUSE
NC score	0.489453 (rank : 14)	θ value	6.85773e-16 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	521	Shared Neighborhood Hits	26
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NCOR2_HUMAN
NC score	0.488680 (rank : 15)	θ value	1.92812e-18 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	870	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR1_HUMAN
NC score	0.483127 (rank : 16)	θ value	1.52774e-15 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR2_MOUSE
NC score	0.478294 (rank : 17)	θ value	1.80466e-16 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	790	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MIER1_MOUSE
NC score	0.462567 (rank : 18)	θ value	2.44474e-05 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

MIER1_HUMAN
NC score	0.458124 (rank : 19)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

TREF1_HUMAN
NC score	0.378194 (rank : 20)	θ value	1.53129e-07 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	651	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TREF1_MOUSE
NC score	0.375363 (rank : 21)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	682	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

RERE_MOUSE
NC score	0.336555 (rank : 22)	θ value	2.88788e-06 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RERE_HUMAN
NC score	0.334064 (rank : 23)	θ value	4.92598e-06 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MYSM1_MOUSE
NC score	0.244799 (rank : 24)	θ value	0.00228821 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

MYSM1_HUMAN
NC score	0.244039 (rank : 25)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

ATN1_HUMAN
NC score	0.065008 (rank : 26)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	676	Shared Neighborhood Hits	12
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MDC1_MOUSE
NC score	0.056954 (rank : 27)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	998	Shared Neighborhood Hits	17
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDC1_HUMAN
NC score	0.056732 (rank : 28)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	1446	Shared Neighborhood Hits	19
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DCP1A_HUMAN
NC score	0.056555 (rank : 29)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

SON_HUMAN
NC score	0.054860 (rank : 30)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CJ108_HUMAN
NC score	0.054557 (rank : 31)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

GA2L2_MOUSE
NC score	0.054422 (rank : 32)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

FA47B_HUMAN
NC score	0.053790 (rank : 33)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TRAIP_MOUSE
NC score	0.044637 (rank : 34)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	745	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

NIN_HUMAN
NC score	0.041628 (rank : 35)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	1416	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

GSTK1_HUMAN
NC score	0.039007 (rank : 36)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q3, Q9P1S4	Gene names	GSTK1
Domain Architecture
Description	Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (Glutathione S-transferase subunit 13) (GST class-kappa) (GSTK1-1) (hGSTK1).

CUTL2_HUMAN
NC score	0.035428 (rank : 37)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	906	Shared Neighborhood Hits	24
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

TRAIP_HUMAN
NC score	0.032561 (rank : 38)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	780	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

PNMA1_HUMAN
NC score	0.032315 (rank : 39)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8ND90, O95144, Q8NG07	Gene names	PNMA1, MA1
Domain Architecture	No domain graphic available
Description	Paraneoplastic antigen Ma1 (Neuron- and testis-specific protein 1) (37 kDa neuronal protein).

MD1L1_HUMAN
NC score	0.031097 (rank : 40)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	893	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

TPR_HUMAN
NC score	0.025767 (rank : 41)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

KCD18_HUMAN
NC score	0.025648 (rank : 42)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

RHG12_HUMAN
NC score	0.024674 (rank : 43)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MYH3_HUMAN
NC score	0.023752 (rank : 44)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	1660	Shared Neighborhood Hits	26
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

RHG12_MOUSE
NC score	0.023474 (rank : 45)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MYH7_HUMAN
NC score	0.020675 (rank : 46)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	1559	Shared Neighborhood Hits	23
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH11_MOUSE
NC score	0.020103 (rank : 47)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	1777	Shared Neighborhood Hits	26
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH8_MOUSE
NC score	0.020083 (rank : 48)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	1600	Shared Neighborhood Hits	25
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_HUMAN
NC score	0.019403 (rank : 49)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	1610	Shared Neighborhood Hits	27
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SMC2_HUMAN
NC score	0.019134 (rank : 50)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

MYH4_MOUSE
NC score	0.018868 (rank : 51)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	1476	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

PLCB1_HUMAN
NC score	0.018604 (rank : 52)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	614	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

GRIN1_HUMAN
NC score	0.017855 (rank : 53)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	681	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MYH11_HUMAN
NC score	0.017807 (rank : 54)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	1806	Shared Neighborhood Hits	26
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BIRC6_HUMAN
NC score	0.017623 (rank : 55)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

NEST_HUMAN
NC score	0.017496 (rank : 56)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	1305	Shared Neighborhood Hits	27
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RAD18_MOUSE
NC score	0.017419 (rank : 57)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

SPTA1_MOUSE
NC score	0.017247 (rank : 58)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	675	Shared Neighborhood Hits	19
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CCD45_MOUSE
NC score	0.016060 (rank : 59)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	663	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CKAP4_MOUSE
NC score	0.015859 (rank : 60)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	596	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

FILA_HUMAN
NC score	0.015208 (rank : 61)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	685	Shared Neighborhood Hits	9
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RBP1_HUMAN
NC score	0.013850 (rank : 62)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	521	Shared Neighborhood Hits	21
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

NUPL_MOUSE
NC score	0.012256 (rank : 63)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

JHD1B_MOUSE
NC score	0.010347 (rank : 64)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

PRDM2_HUMAN
NC score	0.006110 (rank : 65)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

AP3D1_HUMAN
NC score	0.006058 (rank : 66)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

NTRK2_HUMAN
NC score	-0.001419 (rank : 67)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	1081	Shared Neighborhood Hits	3
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
NC score	-0.001439 (rank : 68)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	1088	Shared Neighborhood Hits	3
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).