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Network neighborhood for query Sequence : DONS_HUMAN

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DONS_HUMAN
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DONS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

DONS_MOUSE
θ value	0 (rank : 2)	NC score	0.993457 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXP4, Q80V93, Q8BV55	Gene names	Donson, ORF60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (Protein 3SG).

RETST_MOUSE
θ value	0.813845 (rank : 3)	NC score	0.046502 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

DPOLA_HUMAN
θ value	2.36792 (rank : 4)	NC score	0.027069 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

ITAX_MOUSE
θ value	2.36792 (rank : 5)	NC score	0.015923 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

TTC16_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.027936 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SMBT1_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.031376 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

SON_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.009135 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	1568	Shared Neighborhood Hits	4
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TITIN_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.003225 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ITAX_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.013402 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

LAP2_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.005957 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	499	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

USP9X_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.009681 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

CN044_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.016695 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

HRX_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.009315 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	825	Shared Neighborhood Hits	4
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SMBT1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.022082 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

TULP4_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.010680 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	426	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

Hits sorted by NC score

DONS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

DONS_MOUSE
NC score	0.993457 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXP4, Q80V93, Q8BV55	Gene names	Donson, ORF60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (Protein 3SG).

RETST_MOUSE
NC score	0.046502 (rank : 3)	θ value	0.813845 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

SMBT1_MOUSE
NC score	0.031376 (rank : 4)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

TTC16_MOUSE
NC score	0.027936 (rank : 5)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DPOLA_HUMAN
NC score	0.027069 (rank : 6)	θ value	2.36792 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

SMBT1_HUMAN
NC score	0.022082 (rank : 7)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

CN044_MOUSE
NC score	0.016695 (rank : 8)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

ITAX_MOUSE
NC score	0.015923 (rank : 9)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

ITAX_HUMAN
NC score	0.013402 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

TULP4_HUMAN
NC score	0.010680 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	426	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

USP9X_MOUSE
NC score	0.009681 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

HRX_HUMAN
NC score	0.009315 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	825	Shared Neighborhood Hits	4
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SON_HUMAN
NC score	0.009135 (rank : 14)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	1568	Shared Neighborhood Hits	4
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

LAP2_HUMAN
NC score	0.005957 (rank : 15)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	499	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

TITIN_HUMAN
NC score	0.003225 (rank : 16)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).