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Network neighborhood for query Sequence : DPP8_HUMAN

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DPP8_HUMAN
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPP8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
θ value	0 (rank : 2)	NC score	0.999147 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

DPP9_HUMAN
θ value	0 (rank : 3)	NC score	0.992018 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
θ value	0 (rank : 4)	NC score	0.991734 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP4_HUMAN
θ value	3.85808e-43 (rank : 5)	NC score	0.781021 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_MOUSE
θ value	5.39604e-37 (rank : 6)	NC score	0.774356 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

SEPR_MOUSE
θ value	1.57e-36 (rank : 7)	NC score	0.768297 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

SEPR_HUMAN
θ value	4.27553e-34 (rank : 8)	NC score	0.765059 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

DPP10_HUMAN
θ value	5.584e-34 (rank : 9)	NC score	0.759469 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP10_MOUSE
θ value	9.52487e-34 (rank : 10)	NC score	0.757404 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP6_MOUSE
θ value	2.34606e-32 (rank : 11)	NC score	0.760431 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_HUMAN
θ value	2.59387e-31 (rank : 12)	NC score	0.757358 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

APEH_MOUSE
θ value	1.80886e-08 (rank : 13)	NC score	0.453917 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

ACPH_HUMAN
θ value	8.97725e-08 (rank : 14)	NC score	0.444808 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

NLGN2_MOUSE
θ value	0.00509761 (rank : 15)	NC score	0.063800 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.063738 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

CO6A2_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.014777 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

EST2_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.050373 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

PPCE_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.126105 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PPCE_MOUSE
θ value	0.279714 (rank : 20)	NC score	0.120451 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

DUS1_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.025805 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

CYLC1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.021828 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

ESTN_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.026906 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

KPSH1_HUMAN
θ value	3.0926 (rank : 24)	NC score	-0.001163 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).

DUS1_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.016748 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

MUC5B_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.004634 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	1020	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PAFA2_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.056107 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q99487, O15458	Gene names	PAFAH2
Domain Architecture
Description	Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (HSD-PLA2).

DHX9_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.005343 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

S5A1_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.019489 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P18405, Q9UHY4, Q9UP36, Q9UP37	Gene names	SRD5A1
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) (Steroid 5- alpha-reductase 1) (SR type 1) (S5AR).

AFF1_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.005249 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

Hits sorted by NC score

DPP8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
NC score	0.999147 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

DPP9_HUMAN
NC score	0.992018 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
NC score	0.991734 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP4_HUMAN
NC score	0.781021 (rank : 5)	θ value	3.85808e-43 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_MOUSE
NC score	0.774356 (rank : 6)	θ value	5.39604e-37 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

SEPR_MOUSE
NC score	0.768297 (rank : 7)	θ value	1.57e-36 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

SEPR_HUMAN
NC score	0.765059 (rank : 8)	θ value	4.27553e-34 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	15
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

DPP6_MOUSE
NC score	0.760431 (rank : 9)	θ value	2.34606e-32 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP10_HUMAN
NC score	0.759469 (rank : 10)	θ value	5.584e-34 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP10_MOUSE
NC score	0.757404 (rank : 11)	θ value	9.52487e-34 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP6_HUMAN
NC score	0.757358 (rank : 12)	θ value	2.59387e-31 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

APEH_MOUSE
NC score	0.453917 (rank : 13)	θ value	1.80886e-08 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

ACPH_HUMAN
NC score	0.444808 (rank : 14)	θ value	8.97725e-08 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

PPCE_HUMAN
NC score	0.126105 (rank : 15)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PPCE_MOUSE
NC score	0.120451 (rank : 16)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

NLGN2_MOUSE
NC score	0.063800 (rank : 17)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
NC score	0.063738 (rank : 18)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

PAFA2_HUMAN
NC score	0.056107 (rank : 19)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q99487, O15458	Gene names	PAFAH2
Domain Architecture
Description	Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (HSD-PLA2).

EST2_HUMAN
NC score	0.050373 (rank : 20)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

ESTN_MOUSE
NC score	0.026906 (rank : 21)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

DUS1_MOUSE
NC score	0.025805 (rank : 22)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

CYLC1_HUMAN
NC score	0.021828 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

S5A1_HUMAN
NC score	0.019489 (rank : 24)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P18405, Q9UHY4, Q9UP36, Q9UP37	Gene names	SRD5A1
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) (Steroid 5- alpha-reductase 1) (SR type 1) (S5AR).

DUS1_HUMAN
NC score	0.016748 (rank : 25)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

CO6A2_HUMAN
NC score	0.014777 (rank : 26)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

DHX9_MOUSE
NC score	0.005343 (rank : 27)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

AFF1_MOUSE
NC score	0.005249 (rank : 28)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MUC5B_HUMAN
NC score	0.004634 (rank : 29)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	1020	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KPSH1_HUMAN
NC score	-0.001163 (rank : 30)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P11801, Q9NY19	Gene names	PSKH1
Domain Architecture
Description	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).