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Network neighborhood for query Sequence : NEU2_HUMAN

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NEU2_HUMAN
SwissProt Accessions	P01185, O14935	Gene names	AVP, ARVP, VP
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-II); Copeptin].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NEU2_HUMAN
θ value	4.19693e-98 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P01185, O14935	Gene names	AVP, ARVP, VP
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-II); Copeptin].

NEU2_MOUSE
θ value	2.82823e-78 (rank : 2)	NC score	0.987915 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P35455	Gene names	Avp
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-I); Copeptin].

NEU1_MOUSE
θ value	1.08223e-53 (rank : 3)	NC score	0.969034 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NEU1_HUMAN
θ value	2.66562e-52 (rank : 4)	NC score	0.978417 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	P01178, Q3MIG0	Gene names	OXT, OT
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

KR106_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.066487 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	347	Shared Neighborhood Hits	27
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.063577 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

TIE1_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.024400 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	1266	Shared Neighborhood Hits	28
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TENX_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.046333 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	789	Shared Neighborhood Hits	33
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KRA58_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.079050 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ERBB3_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.022134 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	918	Shared Neighborhood Hits	16
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

KRA55_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.079465 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NID2_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.029857 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	456	Shared Neighborhood Hits	17
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LRP2_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.043570 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	573	Shared Neighborhood Hits	32
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

TMPS6_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.015391 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA11_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.021443 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.021431 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	263	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

PGBM_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.031495 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	1113	Shared Neighborhood Hits	32
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TIE1_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.022436 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TMPS6_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.015248 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

KR107_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.057041 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	330	Shared Neighborhood Hits	29
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR10C_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.072761 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA51_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.061983 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LRP1B_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.036516 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF8_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.040443 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	528	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.038046 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	520	Shared Neighborhood Hits	27
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NELL2_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.033739 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

STAB2_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.037435 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	534	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

JAG2_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.032924 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.035126 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LRP8_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.036440 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	346	Shared Neighborhood Hits	25
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ERBB3_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.016141 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	898	Shared Neighborhood Hits	13
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

KR108_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.051461 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA54_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.040013 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

AGRIN_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.033496 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	582	Shared Neighborhood Hits	30
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

GRN_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.040266 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

NELL2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.032226 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	449	Shared Neighborhood Hits	30
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

RET_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.007428 (rank : 43)
Query Neighborhood Hits	37	Target Neighborhood Hits	884	Shared Neighborhood Hits	6
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

KR103_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.051900 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.053905 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR171_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.077043 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LCE2B_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.107661 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.095336 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.135249 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

Hits sorted by NC score

NEU2_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.19693e-98 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P01185, O14935	Gene names	AVP, ARVP, VP
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-II); Copeptin].

NEU2_MOUSE
NC score	0.987915 (rank : 2)	θ value	2.82823e-78 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P35455	Gene names	Avp
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-I); Copeptin].

NEU1_HUMAN
NC score	0.978417 (rank : 3)	θ value	2.66562e-52 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	P01178, Q3MIG0	Gene names	OXT, OT
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NEU1_MOUSE
NC score	0.969034 (rank : 4)	θ value	1.08223e-53 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

LCE2D_HUMAN
NC score	0.135249 (rank : 5)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE2B_HUMAN
NC score	0.107661 (rank : 6)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
NC score	0.095336 (rank : 7)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

KRA55_HUMAN
NC score	0.079465 (rank : 8)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA58_HUMAN
NC score	0.079050 (rank : 9)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR171_HUMAN
NC score	0.077043 (rank : 10)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR10C_HUMAN
NC score	0.072761 (rank : 11)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR106_HUMAN
NC score	0.066487 (rank : 12)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	347	Shared Neighborhood Hits	27
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
NC score	0.063577 (rank : 13)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA51_HUMAN
NC score	0.061983 (rank : 14)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KR107_HUMAN
NC score	0.057041 (rank : 15)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	330	Shared Neighborhood Hits	29
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR105_HUMAN
NC score	0.053905 (rank : 16)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR103_HUMAN
NC score	0.051900 (rank : 17)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR108_HUMAN
NC score	0.051461 (rank : 18)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

TENX_HUMAN
NC score	0.046333 (rank : 19)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	789	Shared Neighborhood Hits	33
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP2_HUMAN
NC score	0.043570 (rank : 20)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	573	Shared Neighborhood Hits	32
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MEGF8_HUMAN
NC score	0.040443 (rank : 21)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	528	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

GRN_MOUSE
NC score	0.040266 (rank : 22)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA54_HUMAN
NC score	0.040013 (rank : 23)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MEGF8_MOUSE
NC score	0.038046 (rank : 24)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	520	Shared Neighborhood Hits	27
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB2_HUMAN
NC score	0.037435 (rank : 25)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	534	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LRP1B_HUMAN
NC score	0.036516 (rank : 26)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP8_HUMAN
NC score	0.036440 (rank : 27)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	346	Shared Neighborhood Hits	25
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

JAG2_MOUSE
NC score	0.035126 (rank : 28)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NELL2_MOUSE
NC score	0.033739 (rank : 29)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

AGRIN_HUMAN
NC score	0.033496 (rank : 30)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	582	Shared Neighborhood Hits	30
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

JAG2_HUMAN
NC score	0.032924 (rank : 31)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NELL2_HUMAN
NC score	0.032226 (rank : 32)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	449	Shared Neighborhood Hits	30
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PGBM_HUMAN
NC score	0.031495 (rank : 33)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	1113	Shared Neighborhood Hits	32
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NID2_HUMAN
NC score	0.029857 (rank : 34)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	456	Shared Neighborhood Hits	17
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TIE1_MOUSE
NC score	0.024400 (rank : 35)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	1266	Shared Neighborhood Hits	28
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_HUMAN
NC score	0.022436 (rank : 36)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ERBB3_HUMAN
NC score	0.022134 (rank : 37)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	918	Shared Neighborhood Hits	16
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ADA11_HUMAN
NC score	0.021443 (rank : 38)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.021431 (rank : 39)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	263	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ERBB3_MOUSE
NC score	0.016141 (rank : 40)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	898	Shared Neighborhood Hits	13
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

TMPS6_MOUSE
NC score	0.015391 (rank : 41)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_HUMAN
NC score	0.015248 (rank : 42)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

RET_MOUSE
NC score	0.007428 (rank : 43)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	884	Shared Neighborhood Hits	6
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).