SH23A_HUMAN
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SwissProt Accessions | Q9BRG2, Q9Y2X4 | Gene names | SH2D3A, NSP1 | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing protein 3A (Novel SH2-containing protein 1). | |||||
Rank Plots |
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SH23A_HUMAN
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θ value | 0 (rank : 1) | NC score | 0.999962 (rank : 1) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 149 | Shared Neighborhood Hits | 149 | |
SwissProt Accessions | Q9BRG2, Q9Y2X4 | Gene names | SH2D3A, NSP1 | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing protein 3A (Novel SH2-containing protein 1). |
BCAR3_HUMAN
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θ value | 2.81514e-94 (rank : 2) | NC score | 0.921920 (rank : 2) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 129 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | O75815, Q6UW40, Q9BR50 | Gene names | BCAR3, NSP2, SH2D3B | |||
Domain Architecture |
No domain graphic available |
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Description | Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2). |
BCAR3_MOUSE
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θ value | 3.0147e-88 (rank : 3) | NC score | 0.918700 (rank : 3) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 127 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | Q9QZK2, Q3TNC9, Q3UP10 | Gene names | Bcar3, And34 | |||
Domain Architecture |
No domain graphic available |
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Description | Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34). |
SH2D3_HUMAN
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θ value | 2.03155e-68 (rank : 4) | NC score | 0.892190 (rank : 4) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 188 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5 | Gene names | SH2D3C, NSP3 | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing protein 3C (Novel SH2-containing protein 3). |
SH2D3_MOUSE
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θ value | 3.83135e-67 (rank : 5) | NC score | 0.890637 (rank : 5) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 174 | Shared Neighborhood Hits | 84 | |
SwissProt Accessions | Q9QZS8, Q9JME1 | Gene names | Sh2d3c, Chat, Shep1 | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer). |
FES_HUMAN
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θ value | 1.9326e-10 (rank : 6) | NC score | 0.149069 (rank : 82) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 978 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P07332 | Gene names | FES, FPS | |||
Domain Architecture |
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Description | Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes). |
SHC1_HUMAN
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θ value | 4.30538e-10 (rank : 7) | NC score | 0.552806 (rank : 6) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 170 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P29353, O15290, Q8N4K5, Q96CL1 | Gene names | SHC1, SHC, SHCA | |||
Domain Architecture |
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Description | SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1). |
SHC1_MOUSE
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θ value | 4.30538e-10 (rank : 8) | NC score | 0.551508 (rank : 7) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 180 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7 | Gene names | Shc1, Shc, ShcA | |||
Domain Architecture |
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Description | SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1). |
FES_MOUSE
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θ value | 1.63604e-09 (rank : 9) | NC score | 0.142137 (rank : 86) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 64 | |
SwissProt Accessions | P16879, Q62122 | Gene names | Fes, Fps | |||
Domain Architecture |
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Description | Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes). |
FER_HUMAN
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θ value | 3.64472e-09 (rank : 10) | NC score | 0.177321 (rank : 68) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1278 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | P16591 | Gene names | FER, TYK3 | |||
Domain Architecture |
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Description | Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER). |
SHC3_MOUSE
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θ value | 1.80886e-08 (rank : 11) | NC score | 0.530354 (rank : 10) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | Q61120 | Gene names | Shc3, Nshc, ShcC | |||
Domain Architecture |
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Description | SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc). |
SHC3_HUMAN
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θ value | 2.61198e-07 (rank : 12) | NC score | 0.523036 (rank : 11) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 155 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q92529, Q8TAP2, Q9UCX5 | Gene names | SHC3, NSHC, SHCC | |||
Domain Architecture |
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Description | SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai). |
SHC2_HUMAN
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θ value | 3.41135e-07 (rank : 13) | NC score | 0.533354 (rank : 9) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 170 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P98077, O60230, Q9NPL5, Q9UCX4 | Gene names | SHC2, SCK, SHCB | |||
Domain Architecture |
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Description | SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck). |
SHC2_MOUSE
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θ value | 5.81887e-07 (rank : 14) | NC score | 0.535343 (rank : 8) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 144 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q8BMC3 | Gene names | Shc2, Sck, ShcB | |||
Domain Architecture |
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Description | SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli). |
SHD_MOUSE
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θ value | 1.29631e-06 (rank : 15) | NC score | 0.448391 (rank : 12) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | O88834, Q3SYI7 | Gene names | Shd | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein D. |
CRK_HUMAN
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θ value | 8.40245e-06 (rank : 16) | NC score | 0.407449 (rank : 21) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 308 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P46108 | Gene names | CRK | |||
Domain Architecture |
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Description | Proto-oncogene C-crk (P38) (Adapter molecule crk). |
CRK_MOUSE
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θ value | 8.40245e-06 (rank : 17) | NC score | 0.399880 (rank : 23) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 314 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | Q64010 | Gene names | Crk, Crko | |||
Domain Architecture |
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Description | Proto-oncogene C-crk (P38) (Adapter molecule crk). |
ABL1_HUMAN
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θ value | 1.43324e-05 (rank : 18) | NC score | 0.164833 (rank : 76) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1220 | Shared Neighborhood Hits | 98 | |
SwissProt Accessions | P00519, Q13869, Q13870, Q16133, Q45F09 | Gene names | ABL1, ABL, JTK7 | |||
Domain Architecture |
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Description | Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). |
ABL1_MOUSE
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θ value | 1.43324e-05 (rank : 19) | NC score | 0.164333 (rank : 77) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1178 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4 | Gene names | Abl1, Abl | |||
Domain Architecture |
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Description | Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). |
ABL2_HUMAN
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θ value | 1.87187e-05 (rank : 20) | NC score | 0.167606 (rank : 74) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1045 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P42684, Q5T0X6, Q6NZY6 | Gene names | ABL2, ABLL, ARG | |||
Domain Architecture |
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Description | Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG). |
GRAP2_HUMAN
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θ value | 2.44474e-05 (rank : 21) | NC score | 0.336267 (rank : 36) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 304 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O75791, O43726 | Gene names | GRAP2, GADS, GRB2L, GRID | |||
Domain Architecture |
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Description | GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona). |
GRAP_HUMAN
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θ value | 3.19293e-05 (rank : 22) | NC score | 0.374047 (rank : 27) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q13588 | Gene names | GRAP | |||
Domain Architecture |
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Description | GRB2-related adapter protein. |
SHD_HUMAN
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θ value | 4.1701e-05 (rank : 23) | NC score | 0.425282 (rank : 18) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 204 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q96IW2, Q96NC2 | Gene names | SHD | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein D. |
GRAP2_MOUSE
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θ value | 5.44631e-05 (rank : 24) | NC score | 0.338384 (rank : 34) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 297 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O89100 | Gene names | Grap2, Gads, Grb2l, Grid, Mona | |||
Domain Architecture |
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Description | GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID). |
GRAP_MOUSE
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θ value | 9.29e-05 (rank : 25) | NC score | 0.370139 (rank : 28) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 309 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q9CX99, Q3U545 | Gene names | Grap | |||
Domain Architecture |
No domain graphic available |
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Description | GRB2-related adapter protein. |
LNK_HUMAN
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θ value | 9.29e-05 (rank : 26) | NC score | 0.445515 (rank : 14) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q9UQQ2, O95184 | Gene names | LNK | |||
Domain Architecture |
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Description | Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein). |
SHE_MOUSE
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θ value | 0.00020696 (rank : 27) | NC score | 0.407843 (rank : 20) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 169 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q8BSD5, Q3TZT0 | Gene names | She | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein E. |
SHE_HUMAN
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θ value | 0.000270298 (rank : 28) | NC score | 0.410392 (rank : 19) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 164 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q5VZ18, Q8TEQ5 | Gene names | SHE | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein E. |
NCK1_HUMAN
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θ value | 0.000602161 (rank : 29) | NC score | 0.352878 (rank : 32) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 312 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P16333 | Gene names | NCK1, NCK | |||
Domain Architecture |
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Description | Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha). |
CRKL_HUMAN
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θ value | 0.000786445 (rank : 30) | NC score | 0.395543 (rank : 24) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 313 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P46109 | Gene names | CRKL | |||
Domain Architecture |
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Description | Crk-like protein. |
SRMS_MOUSE
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θ value | 0.00102713 (rank : 31) | NC score | 0.127052 (rank : 101) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 964 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q62270, Q62360, Q923M5 | Gene names | Srms, Srm | |||
Domain Architecture |
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Description | Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70). |
APS_HUMAN
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θ value | 0.00175202 (rank : 32) | NC score | 0.446332 (rank : 13) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 162 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | O14492 | Gene names | APS | |||
Domain Architecture |
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Description | SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains). |
APS_MOUSE
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θ value | 0.00175202 (rank : 33) | NC score | 0.407163 (rank : 22) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 134 | Shared Neighborhood Hits | 77 | |
SwissProt Accessions | Q9JID9, O88936 | Gene names | Aps | |||
Domain Architecture |
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Description | SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains). |
CRKL_MOUSE
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θ value | 0.00175202 (rank : 34) | NC score | 0.394765 (rank : 25) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P47941, Q3TQ18, Q8BGC5 | Gene names | Crkl, Crkol | |||
Domain Architecture |
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Description | Crk-like protein. |
LNK_MOUSE
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θ value | 0.00175202 (rank : 35) | NC score | 0.436818 (rank : 16) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 132 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | O09039 | Gene names | Lnk | |||
Domain Architecture |
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Description | Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein). |
GRB2_HUMAN
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θ value | 0.00228821 (rank : 36) | NC score | 0.358145 (rank : 31) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P62993, P29354, Q14450, Q63057, Q63059 | Gene names | GRB2, ASH | |||
Domain Architecture |
No domain graphic available |
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Description | Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash). |
GRB2_MOUSE
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θ value | 0.00228821 (rank : 37) | NC score | 0.358279 (rank : 30) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 312 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q60631, Q61240 | Gene names | Grb2 | |||
Domain Architecture |
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Description | Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2). |
DAPP1_MOUSE
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θ value | 0.00298849 (rank : 38) | NC score | 0.364847 (rank : 29) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q9QXT1, Q9R178 | Gene names | Dapp1, Bam32 | |||
Domain Architecture |
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Description | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32). |
NCK2_HUMAN
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θ value | 0.00298849 (rank : 39) | NC score | 0.338362 (rank : 35) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | O43639, Q9BWN9, Q9UIC3 | Gene names | NCK2 | |||
Domain Architecture |
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Description | Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2). |
DAPP1_HUMAN
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θ value | 0.00390308 (rank : 40) | NC score | 0.374479 (rank : 26) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q9UN19, Q8TCK5, Q9UHF2 | Gene names | DAPP1, BAM32 | |||
Domain Architecture |
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Description | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32). |
SELV_HUMAN
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θ value | 0.00509761 (rank : 41) | NC score | 0.092259 (rank : 135) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 118 | Shared Neighborhood Hits | 7 | |
SwissProt Accessions | P59797 | Gene names | SELV | |||
Domain Architecture |
No domain graphic available |
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Description | Selenoprotein V. |
CSK_MOUSE
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θ value | 0.00665767 (rank : 42) | NC score | 0.149372 (rank : 81) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41241, Q03143 | Gene names | Csk | |||
Domain Architecture |
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Description | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK). |
HSH2D_HUMAN
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θ value | 0.00665767 (rank : 43) | NC score | 0.339739 (rank : 33) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 159 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | Q96JZ2, Q6ZNG7 | Gene names | HSH2D, ALX | |||
Domain Architecture |
No domain graphic available |
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Description | Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X). |
SHB_HUMAN
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θ value | 0.00665767 (rank : 44) | NC score | 0.434031 (rank : 17) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 141 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q15464, Q504U5, Q5VUM8 | Gene names | SHB | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein B. |
PTN6_MOUSE
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θ value | 0.00869519 (rank : 45) | NC score | 0.202226 (rank : 60) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6 | Gene names | Ptpn6, Hcp, Hcph, Ptp1C | |||
Domain Architecture |
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Description | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42). |
SHB_MOUSE
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θ value | 0.00869519 (rank : 46) | NC score | 0.437583 (rank : 15) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q6PD21, Q3ULM3 | Gene names | Shb | |||
Domain Architecture |
No domain graphic available |
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Description | SH2 domain-containing adapter protein B. |
PTK6_HUMAN
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θ value | 0.0148317 (rank : 47) | NC score | 0.129960 (rank : 94) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1020 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q13882 | Gene names | PTK6, BRK | |||
Domain Architecture |
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Description | Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK). |
PTN11_HUMAN
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θ value | 0.0148317 (rank : 48) | NC score | 0.217862 (rank : 57) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q06124, Q96HD7 | Gene names | PTPN11, PTP2C, SHPTP2 | |||
Domain Architecture |
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Description | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2). |
PTN11_MOUSE
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θ value | 0.0148317 (rank : 49) | NC score | 0.217887 (rank : 56) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P35235, Q3TQ84, Q64509, Q6PCL5 | Gene names | Ptpn11 | |||
Domain Architecture |
No domain graphic available |
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Description | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2). |
PTN6_HUMAN
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θ value | 0.0148317 (rank : 50) | NC score | 0.196063 (rank : 65) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 234 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P29350, Q969V8 | Gene names | PTPN6, HCP, PTP1C | |||
Domain Architecture |
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Description | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1). |
SRMS_HUMAN
|
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θ value | 0.0148317 (rank : 51) | NC score | 0.125074 (rank : 104) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 946 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | Q9H3Y6 | Gene names | SRMS, C20orf148 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Srms (EC 2.7.10.2). |
CSK_HUMAN
|
||||||
θ value | 0.0193708 (rank : 52) | NC score | 0.147739 (rank : 83) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41240, Q6FGZ6 | Gene names | CSK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL). |
MEGF9_HUMAN
|
||||||
θ value | 0.0252991 (rank : 53) | NC score | 0.022439 (rank : 376) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 557 | Shared Neighborhood Hits | 12 | |
SwissProt Accessions | Q9H1U4, O75098 | Gene names | MEGF9, EGFL5, KIAA0818 | |||
Domain Architecture |
|
|||||
Description | Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5). |
BMX_HUMAN
|
||||||
θ value | 0.0330416 (rank : 54) | NC score | 0.111559 (rank : 113) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 942 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | P51813, O60564, Q12871 | Gene names | BMX | |||
Domain Architecture |
|
|||||
Description | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38). |
VAV3_HUMAN
|
||||||
θ value | 0.0431538 (rank : 55) | NC score | 0.223120 (rank : 54) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 398 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q9UKW4, O95230, Q9Y5X8 | Gene names | VAV3 | |||
Domain Architecture |
|
|||||
Description | Protein vav-3. |
BMX_MOUSE
|
||||||
θ value | 0.0563607 (rank : 56) | NC score | 0.109777 (rank : 117) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 912 | Shared Neighborhood Hits | 78 | |
SwissProt Accessions | P97504 | Gene names | Bmx | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog). |
KSYK_HUMAN
|
||||||
θ value | 0.0563607 (rank : 57) | NC score | 0.127412 (rank : 98) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 901 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | P43405 | Gene names | SYK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase). |
MATK_HUMAN
|
||||||
θ value | 0.0563607 (rank : 58) | NC score | 0.136605 (rank : 90) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 954 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P42679 | Gene names | MATK, CTK, HYL | |||
Domain Architecture |
|
|||||
Description | Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase). |
PTK6_MOUSE
|
||||||
θ value | 0.0563607 (rank : 59) | NC score | 0.127872 (rank : 97) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q64434 | Gene names | Ptk6, Sik | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase). |
MATK_MOUSE
|
||||||
θ value | 0.0736092 (rank : 60) | NC score | 0.135683 (rank : 91) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 952 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41242, Q6LE90 | Gene names | Matk, Ctk, Ntk | |||
Domain Architecture |
|
|||||
Description | Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK). |
VAV3_MOUSE
|
||||||
θ value | 0.0736092 (rank : 61) | NC score | 0.222001 (rank : 55) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 404 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q9R0C8, Q7TS85 | Gene names | Vav3 | |||
Domain Architecture |
|
|||||
Description | Protein vav-3. |
RAD21_HUMAN
|
||||||
θ value | 0.0961366 (rank : 62) | NC score | 0.070000 (rank : 154) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 46 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | O60216, Q15001, Q99568 | Gene names | RAD21, HR21, KIAA0078, NXP1 | |||
Domain Architecture |
|
|||||
Description | Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog). |
SH22A_HUMAN
|
||||||
θ value | 0.0961366 (rank : 63) | NC score | 0.264426 (rank : 45) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 144 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q9NP31, O43817, Q9UPA7 | Gene names | SH2D2A, SCAP, TSAD, VRAP | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein). |
TCGAP_HUMAN
|
||||||
θ value | 0.0961366 (rank : 64) | NC score | 0.050572 (rank : 353) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 872 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23 | Gene names | SNX26, TCGAP | |||
Domain Architecture |
|
|||||
Description | TC10/CDC42 GTPase-activating protein (Sorting nexin-26). |
KSYK_MOUSE
|
||||||
θ value | 0.163984 (rank : 65) | NC score | 0.124748 (rank : 105) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 944 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P48025 | Gene names | Syk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase). |
GRB14_HUMAN
|
||||||
θ value | 0.21417 (rank : 66) | NC score | 0.274836 (rank : 43) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q14449, Q7Z6I1 | Gene names | GRB14 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 14 (GRB14 adapter protein). |
DOT1L_HUMAN
|
||||||
θ value | 0.279714 (rank : 67) | NC score | 0.045358 (rank : 361) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 660 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | Q8TEK3, O60379, Q96JL1 | Gene names | DOT1L, KIAA1814 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein). |
RAD21_MOUSE
|
||||||
θ value | 0.279714 (rank : 68) | NC score | 0.066130 (rank : 181) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 59 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q61550, P70219, Q91VB9, Q9DBU4 | Gene names | Rad21, Hr21 | |||
Domain Architecture |
|
|||||
Description | Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog). |
RAI1_HUMAN
|
||||||
θ value | 0.279714 (rank : 69) | NC score | 0.047662 (rank : 359) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 360 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69 | Gene names | RAI1, KIAA1820 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Retinoic acid-induced protein 1. |
SH21B_MOUSE
|
||||||
θ value | 0.279714 (rank : 70) | NC score | 0.291992 (rank : 40) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 101 | Shared Neighborhood Hits | 69 | |
SwissProt Accessions | O35324, Q8C268 | Gene names | Sh2d1b, Eat2, Sh2d1b1 | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2). |
B2L13_HUMAN
|
||||||
θ value | 0.365318 (rank : 71) | NC score | 0.043274 (rank : 364) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 57 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q9BXK5, Q96B37, Q96IB7, Q9BY01, Q9HC05, Q9UFE0, Q9UKN3 | Gene names | BCL2L13, MIL1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo). |
MBD6_HUMAN
|
||||||
θ value | 0.365318 (rank : 72) | NC score | 0.047734 (rank : 358) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 349 | Shared Neighborhood Hits | 17 | |
SwissProt Accessions | Q96DN6, Q8N3M0, Q8NA81, Q96Q00 | Gene names | MBD6, KIAA1887 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6). |
SELPL_MOUSE
|
||||||
θ value | 0.365318 (rank : 73) | NC score | 0.043280 (rank : 363) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 588 | Shared Neighborhood Hits | 24 | |
SwissProt Accessions | Q62170 | Gene names | Selplg, Selp1, Selpl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand). |
SON_HUMAN
|
||||||
θ value | 0.365318 (rank : 74) | NC score | 0.032436 (rank : 368) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1568 | Shared Neighborhood Hits | 44 | |
SwissProt Accessions | P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0 | Gene names | SON, C21orf50, DBP5, KIAA1019, NREBP | |||
Domain Architecture |
|
|||||
Description | SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1). |
VAV2_HUMAN
|
||||||
θ value | 0.365318 (rank : 75) | NC score | 0.201430 (rank : 61) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 453 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | P52735 | Gene names | VAV2 | |||
Domain Architecture |
|
|||||
Description | Protein vav-2. |
RASA1_HUMAN
|
||||||
θ value | 0.47712 (rank : 76) | NC score | 0.303440 (rank : 38) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 258 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | P20936 | Gene names | RASA1, RASA | |||
Domain Architecture |
|
|||||
Description | Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP). |
REL_HUMAN
|
||||||
θ value | 0.62314 (rank : 77) | NC score | 0.021048 (rank : 381) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 31 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | Q04864, Q2PNZ7, Q6LDY0 | Gene names | REL | |||
Domain Architecture |
|
|||||
Description | C-Rel proto-oncogene protein (C-Rel protein). |
FGRL1_HUMAN
|
||||||
θ value | 0.813845 (rank : 78) | NC score | 0.012191 (rank : 392) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 335 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q8N441, Q6PJN1, Q9BXN7, Q9H4D7 | Gene names | FGFRL1, FGFR5, FHFR | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor). |
GRB7_MOUSE
|
||||||
θ value | 0.813845 (rank : 79) | NC score | 0.280921 (rank : 41) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 157 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q03160 | Gene names | Grb7 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7). |
HSH2D_MOUSE
|
||||||
θ value | 0.813845 (rank : 80) | NC score | 0.296757 (rank : 39) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 124 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q6VYH9, Q52KL3 | Gene names | Hsh2d, Alx | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X). |
RAI1_MOUSE
|
||||||
θ value | 0.813845 (rank : 81) | NC score | 0.047211 (rank : 360) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 344 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | Q61818, Q6ZPH7, Q8CEV1 | Gene names | Rai1, Kiaa1820 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Retinoic acid-induced protein 1. |
ROBO3_MOUSE
|
||||||
θ value | 0.813845 (rank : 82) | NC score | 0.010109 (rank : 395) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 524 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q9Z2I4 | Gene names | Robo3, Rbig1 | |||
Domain Architecture |
|
|||||
Description | Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1). |
SH21B_HUMAN
|
||||||
θ value | 0.813845 (rank : 83) | NC score | 0.323565 (rank : 37) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 101 | Shared Neighborhood Hits | 70 | |
SwissProt Accessions | O14796, Q5T0L1, Q8NI18, Q969K9 | Gene names | SH2D1B, EAT2 | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2). |
FMNL_HUMAN
|
||||||
θ value | 1.06291 (rank : 84) | NC score | 0.029031 (rank : 369) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 529 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10 | Gene names | FMNL1, C17orf1, C17orf1B, FMNL | |||
Domain Architecture |
|
|||||
Description | Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13). |
GRB14_MOUSE
|
||||||
θ value | 1.06291 (rank : 85) | NC score | 0.279798 (rank : 42) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 149 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | Q9JLM9, Q3UI77, Q8VDI2, Q9CR03 | Gene names | Grb14 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 14 (GRB14 adapter protein). |
PLCB3_HUMAN
|
||||||
θ value | 1.06291 (rank : 86) | NC score | 0.016402 (rank : 387) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 445 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q01970 | Gene names | PLCB3 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3). |
RPGF3_HUMAN
|
||||||
θ value | 1.06291 (rank : 87) | NC score | 0.065251 (rank : 189) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 56 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | O95398, O95634, Q8WVN0 | Gene names | RAPGEF3, CGEF1, EPAC, EPAC1 | |||
Domain Architecture |
|
|||||
Description | Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). |
RTN4_MOUSE
|
||||||
θ value | 1.06291 (rank : 88) | NC score | 0.021435 (rank : 379) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 341 | Shared Neighborhood Hits | 10 | |
SwissProt Accessions | Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3 | Gene names | Rtn4, Kiaa0886, Nogo | |||
Domain Architecture |
|
|||||
Description | Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein). |
ST5_MOUSE
|
||||||
θ value | 1.06291 (rank : 89) | NC score | 0.016508 (rank : 386) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q924W7, Q78H54, Q8K2P3, Q924W8 | Gene names | St5, Dennd2b | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Suppression of tumorigenicity 5 (DENN domain-containing protein 2B). |
VAV2_MOUSE
|
||||||
θ value | 1.06291 (rank : 90) | NC score | 0.196483 (rank : 64) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 456 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q60992 | Gene names | Vav2 | |||
Domain Architecture |
|
|||||
Description | Protein vav-2. |
MNT_MOUSE
|
||||||
θ value | 1.38821 (rank : 91) | NC score | 0.026760 (rank : 371) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 432 | Shared Neighborhood Hits | 15 | |
SwissProt Accessions | O08789, P97349 | Gene names | Mnt, Rox | |||
Domain Architecture |
|
|||||
Description | Max-binding protein MNT (Protein ROX) (Myc antagonist MNT). |
MSX1_HUMAN
|
||||||
θ value | 1.38821 (rank : 92) | NC score | 0.006174 (rank : 401) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 374 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | P28360, Q96NY4 | Gene names | MSX1, HOX7 | |||
Domain Architecture |
|
|||||
Description | Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7). |
PCNT_HUMAN
|
||||||
θ value | 1.38821 (rank : 93) | NC score | 0.008209 (rank : 397) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1551 | Shared Neighborhood Hits | 21 | |
SwissProt Accessions | O95613, O43152, Q7Z7C9 | Gene names | PCNT, KIAA0402, PCNT2 | |||
Domain Architecture |
|
|||||
Description | Pericentrin (Pericentrin B) (Kendrin). |
RPGF3_MOUSE
|
||||||
θ value | 1.38821 (rank : 94) | NC score | 0.067411 (rank : 167) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 54 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q8VCC8, Q8BZK9, Q8R1R1 | Gene names | Rapgef3, Epac, Epac1 | |||
Domain Architecture |
|
|||||
Description | Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1). |
TIMD1_MOUSE
|
||||||
θ value | 1.38821 (rank : 95) | NC score | 0.024219 (rank : 375) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 97 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2 | Gene names | Havcr1, Tim1, Timd1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1). |
ZYX_HUMAN
|
||||||
θ value | 1.38821 (rank : 96) | NC score | 0.012645 (rank : 391) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 387 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | Q15942 | Gene names | ZYX | |||
Domain Architecture |
|
|||||
Description | Zyxin (Zyxin-2). |
BLNK_MOUSE
|
||||||
θ value | 1.81305 (rank : 97) | NC score | 0.108871 (rank : 119) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 296 | Shared Neighborhood Hits | 47 | |
SwissProt Accessions | Q9QUN3, O88504 | Gene names | Blnk, Bash, Ly57, Slp65 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57). |
CHIN_MOUSE
|
||||||
θ value | 1.81305 (rank : 98) | NC score | 0.144007 (rank : 85) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 229 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3 | Gene names | Chn1, Arhgap2 | |||
Domain Architecture |
|
|||||
Description | N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2). |
FMNL_MOUSE
|
||||||
θ value | 1.81305 (rank : 99) | NC score | 0.027368 (rank : 370) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 428 | Shared Neighborhood Hits | 12 | |
SwissProt Accessions | Q9JL26, Q6KAN4, Q9Z2V7 | Gene names | Fmnl1, Frl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Formin-like protein 1 (Formin-related protein). |
NKX24_MOUSE
|
||||||
θ value | 1.81305 (rank : 100) | NC score | 0.006876 (rank : 399) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 356 | Shared Neighborhood Hits | 5 | |
SwissProt Accessions | Q9EQM3, Q9EQM4 | Gene names | Nkx2-4, Nkx2d | |||
Domain Architecture |
|
|||||
Description | Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D). |
RIMB1_HUMAN
|
||||||
θ value | 1.81305 (rank : 101) | NC score | 0.036051 (rank : 366) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1479 | Shared Neighborhood Hits | 45 | |
SwissProt Accessions | O95153, O75111, Q8N5W3 | Gene names | BZRAP1, KIAA0612, RBP1 | |||
Domain Architecture |
|
|||||
Description | Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1). |
SH24A_MOUSE
|
||||||
θ value | 1.81305 (rank : 102) | NC score | 0.216365 (rank : 58) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 326 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q9D7V1 | Gene names | Sh2d4a | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 4A. |
FGR_MOUSE
|
||||||
θ value | 2.36792 (rank : 103) | NC score | 0.138135 (rank : 89) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1069 | Shared Neighborhood Hits | 98 | |
SwissProt Accessions | P14234, Q61404 | Gene names | Fgr | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR). |
MLL3_HUMAN
|
||||||
θ value | 2.36792 (rank : 104) | NC score | 0.024971 (rank : 372) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1644 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7 | Gene names | MLL3, HALR, KIAA1506 | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein). |
SH22A_MOUSE
|
||||||
θ value | 2.36792 (rank : 105) | NC score | 0.268332 (rank : 44) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 179 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q9QXK9, Q9JHP6 | Gene names | Sh2d2a, Lad, Ribp | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp). |
SOCS6_HUMAN
|
||||||
θ value | 2.36792 (rank : 106) | NC score | 0.166965 (rank : 75) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 63 | |
SwissProt Accessions | O14544 | Gene names | SOCS6, CIS4, SOCS4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4). |
SOCS6_MOUSE
|
||||||
θ value | 2.36792 (rank : 107) | NC score | 0.173828 (rank : 70) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 146 | Shared Neighborhood Hits | 65 | |
SwissProt Accessions | Q9JLY0, Q9D2A0 | Gene names | Socs6, Cis4, Cish4, Socs4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4). |
LCP2_HUMAN
|
||||||
θ value | 3.0926 (rank : 108) | NC score | 0.120079 (rank : 108) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 531 | Shared Neighborhood Hits | 63 | |
SwissProt Accessions | Q13094 | Gene names | LCP2 | |||
Domain Architecture |
|
|||||
Description | Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76). |
LCP2_MOUSE
|
||||||
θ value | 3.0926 (rank : 109) | NC score | 0.132056 (rank : 93) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 177 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q60787 | Gene names | Lcp2 | |||
Domain Architecture |
|
|||||
Description | Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76). |
LIPS_MOUSE
|
||||||
θ value | 3.0926 (rank : 110) | NC score | 0.020035 (rank : 383) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 17 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P54310, P97866, Q3TE34, Q6GU16 | Gene names | Lipe | |||
Domain Architecture |
|
|||||
Description | Hormone-sensitive lipase (EC 3.1.1.79) (HSL). |
SELPL_HUMAN
|
||||||
θ value | 3.0926 (rank : 111) | NC score | 0.044941 (rank : 362) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 68 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q14242, Q12775 | Gene names | SELPLG | |||
Domain Architecture |
No domain graphic available |
|||||
Description | P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen). |
SH24A_HUMAN
|
||||||
θ value | 3.0926 (rank : 112) | NC score | 0.197223 (rank : 63) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 455 | Shared Neighborhood Hits | 64 | |
SwissProt Accessions | Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7 | Gene names | SH2D4A, SH2A | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 4A (Protein SH(2)A). |
SOCS5_HUMAN
|
||||||
θ value | 3.0926 (rank : 113) | NC score | 0.087326 (rank : 136) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 91 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | O75159, Q8IYZ4 | Gene names | SOCS5, CIS6, CISH5, CISH6, KIAA0671 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6). |
SOCS5_MOUSE
|
||||||
θ value | 3.0926 (rank : 114) | NC score | 0.087224 (rank : 137) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 93 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | O54928 | Gene names | Socs5, Cish5 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5). |
YES_MOUSE
|
||||||
θ value | 3.0926 (rank : 115) | NC score | 0.126701 (rank : 103) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1052 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | Q04736 | Gene names | Yes1, Yes | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes). |
BASP_HUMAN
|
||||||
θ value | 4.03905 (rank : 116) | NC score | 0.022030 (rank : 377) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 321 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | P80723, O43596, Q5U0S0 | Gene names | BASP1, NAP22 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein). |
MUC2_HUMAN
|
||||||
θ value | 4.03905 (rank : 117) | NC score | 0.012936 (rank : 390) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 906 | Shared Neighborhood Hits | 17 | |
SwissProt Accessions | Q02817, Q14878 | Gene names | MUC2, SMUC | |||
Domain Architecture |
|
|||||
Description | Mucin-2 precursor (Intestinal mucin-2). |
P85B_HUMAN
|
||||||
θ value | 4.03905 (rank : 118) | NC score | 0.173886 (rank : 69) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 543 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O00459, Q9UPH9 | Gene names | PIK3R2 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta). |
PODXL_MOUSE
|
||||||
θ value | 4.03905 (rank : 119) | NC score | 0.024445 (rank : 374) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 130 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q9R0M4, Q9ESZ1 | Gene names | Podxl, Pclp1 | |||
Domain Architecture |
|
|||||
Description | Podocalyxin-like protein 1 precursor. |
SNPC4_MOUSE
|
||||||
θ value | 4.03905 (rank : 120) | NC score | 0.019378 (rank : 384) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 237 | Shared Neighborhood Hits | 13 | |
SwissProt Accessions | Q8BP86, Q6PGG7, Q80UG9, Q810L1 | Gene names | Snapc4 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit). |
TIRAP_HUMAN
|
||||||
θ value | 4.03905 (rank : 121) | NC score | 0.020690 (rank : 382) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 33 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P58753, Q8N5E5 | Gene names | TIRAP, MAL | |||
Domain Architecture |
|
|||||
Description | Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt). |
YES_HUMAN
|
||||||
θ value | 4.03905 (rank : 122) | NC score | 0.126919 (rank : 102) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1059 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P07947 | Gene names | YES1, YES | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes). |
ZAP70_HUMAN
|
||||||
θ value | 4.03905 (rank : 123) | NC score | 0.097833 (rank : 131) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 893 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | P43403 | Gene names | ZAP70, SRK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase). |
ZAP70_MOUSE
|
||||||
θ value | 4.03905 (rank : 124) | NC score | 0.098897 (rank : 130) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 905 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | P43404 | Gene names | Zap70, Srk, Zap-70 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase). |
CHIN_HUMAN
|
||||||
θ value | 5.27518 (rank : 125) | NC score | 0.134643 (rank : 92) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P15882, Q53SD6, Q53SH5, Q96FB0 | Gene names | CHN1, ARHGAP2, CHN | |||
Domain Architecture |
|
|||||
Description | N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2). |
CS016_HUMAN
|
||||||
θ value | 5.27518 (rank : 126) | NC score | 0.024931 (rank : 373) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 14 | |
SwissProt Accessions | Q8ND99 | Gene names | C19orf16 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Uncharacterized protein C19orf16. |
MLL2_HUMAN
|
||||||
θ value | 5.27518 (rank : 127) | NC score | 0.021364 (rank : 380) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1788 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | O14686, O14687 | Gene names | MLL2, ALR | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein). |
MLL3_MOUSE
|
||||||
θ value | 5.27518 (rank : 128) | NC score | 0.021435 (rank : 378) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1399 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6 | Gene names | Mll3 | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3). |
PLCG2_HUMAN
|
||||||
θ value | 5.27518 (rank : 129) | NC score | 0.240216 (rank : 49) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 280 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P16885, Q969T5 | Gene names | PLCG2 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV). |
RERE_HUMAN
|
||||||
θ value | 5.27518 (rank : 130) | NC score | 0.017983 (rank : 385) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 779 | Shared Neighborhood Hits | 19 | |
SwissProt Accessions | Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4 | Gene names | RERE, ARG, ARP, ATN1L, KIAA0458 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein). |
ZNF31_HUMAN
|
||||||
θ value | 5.27518 (rank : 131) | NC score | -0.004964 (rank : 405) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 769 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P17040, Q96H84 | Gene names | ZNF31, KOX29, ZNF360, ZSCAN20 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360). |
AGRIN_HUMAN
|
||||||
θ value | 6.88961 (rank : 132) | NC score | 0.004557 (rank : 403) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 582 | Shared Neighborhood Hits | 9 | |
SwissProt Accessions | O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4 | Gene names | AGRIN, AGRN | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Agrin precursor. |
ANR38_HUMAN
|
||||||
θ value | 6.88961 (rank : 133) | NC score | 0.003641 (rank : 404) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 443 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3 | Gene names | ANKRD38 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Ankyrin repeat domain-containing protein 38. |
B4GN1_HUMAN
|
||||||
θ value | 6.88961 (rank : 134) | NC score | 0.011006 (rank : 394) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 13 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q00973 | Gene names | B4GALNT1, GALGT, SIAT2 | |||
Domain Architecture |
|
|||||
Description | Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T). |
GRB7_HUMAN
|
||||||
θ value | 6.88961 (rank : 135) | NC score | 0.264415 (rank : 46) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 156 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q14451, Q92568, Q96DF9 | Gene names | GRB7 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47). |
HCFC1_MOUSE
|
||||||
θ value | 6.88961 (rank : 136) | NC score | 0.011841 (rank : 393) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 348 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2 | Gene names | Hcfc1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]. |
ROBO3_HUMAN
|
||||||
θ value | 6.88961 (rank : 137) | NC score | 0.005354 (rank : 402) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 570 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q96MS0 | Gene names | ROBO3 | |||
Domain Architecture |
|
|||||
Description | Roundabout homolog 3 precursor (Roundabout-like protein 3). |
SAFB1_HUMAN
|
||||||
θ value | 6.88961 (rank : 138) | NC score | 0.009975 (rank : 396) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 493 | Shared Neighborhood Hits | 7 | |
SwissProt Accessions | Q15424, O60406, Q59HH8 | Gene names | SAFB, HAP, HET, SAFB1 | |||
Domain Architecture |
|
|||||
Description | Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein). |
SAFB2_HUMAN
|
||||||
θ value | 6.88961 (rank : 139) | NC score | 0.007700 (rank : 398) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 720 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q14151, Q8TB13 | Gene names | SAFB2, KIAA0138 | |||
Domain Architecture |
|
|||||
Description | Scaffold attachment factor B2. |
VAV_HUMAN
|
||||||
θ value | 6.88961 (rank : 140) | NC score | 0.211781 (rank : 59) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 452 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P15498, Q15860 | Gene names | VAV1, VAV | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene vav. |
WNK2_HUMAN
|
||||||
θ value | 6.88961 (rank : 141) | NC score | 0.035896 (rank : 367) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1407 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4 | Gene names | WNK2, KIAA1760, PRKWNK2 | |||
Domain Architecture |
|
|||||
Description | Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2). |
ASPP1_MOUSE
|
||||||
θ value | 8.99809 (rank : 142) | NC score | 0.039301 (rank : 365) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1244 | Shared Neighborhood Hits | 46 | |
SwissProt Accessions | Q62415 | Gene names | Ppp1r13b, Aspp1 | |||
Domain Architecture |
|
|||||
Description | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B). |
BAT3_MOUSE
|
||||||
θ value | 8.99809 (rank : 143) | NC score | 0.014753 (rank : 389) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 518 | Shared Neighborhood Hits | 18 | |
SwissProt Accessions | Q9Z1R2, Q8SNA3 | Gene names | Bat3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Large proline-rich protein BAT3 (HLA-B-associated transcript 3). |
CALX_HUMAN
|
||||||
θ value | 8.99809 (rank : 144) | NC score | 0.006369 (rank : 400) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 96 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | P27824 | Gene names | CANX | |||
Domain Architecture |
|
|||||
Description | Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90). |
CHIO_HUMAN
|
||||||
θ value | 8.99809 (rank : 145) | NC score | 0.103038 (rank : 127) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 220 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | P52757, Q75MM2 | Gene names | CHN2, ARHGAP3, BCH | |||
Domain Architecture |
|
|||||
Description | Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3). |
LCK_HUMAN
|
||||||
θ value | 8.99809 (rank : 146) | NC score | 0.113991 (rank : 111) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 987 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8 | Gene names | LCK | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase). |
LCK_MOUSE
|
||||||
θ value | 8.99809 (rank : 147) | NC score | 0.113039 (rank : 112) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 981 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | P06240, Q61794, Q61795, Q62320, Q91X65 | Gene names | Lck, Lsk-t | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK). |
RERE_MOUSE
|
||||||
θ value | 8.99809 (rank : 148) | NC score | 0.016381 (rank : 388) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 785 | Shared Neighborhood Hits | 21 | |
SwissProt Accessions | Q80TZ9 | Gene names | Rere, Atr2, Kiaa0458 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Arginine-glutamic acid dipeptide repeats protein (Atrophin-2). |
SLAP2_HUMAN
|
||||||
θ value | 8.99809 (rank : 149) | NC score | 0.197762 (rank : 62) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 139 | Shared Neighborhood Hits | 75 | |
SwissProt Accessions | Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135 | Gene names | SLA2, C20orf156, SLAP2 | |||
Domain Architecture |
|
|||||
Description | Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS). |
AATK_HUMAN
|
||||||
θ value | θ > 10 (rank : 150) | NC score | 0.065134 (rank : 191) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1243 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q6ZMQ8, O75136, Q6ZN31, Q86X28 | Gene names | AATK, KIAA0641 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP). |
AATK_MOUSE
|
||||||
θ value | θ > 10 (rank : 151) | NC score | 0.066789 (rank : 174) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 942 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2 | Gene names | Aatk, Kiaa0641 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase). |
ABI2_HUMAN
|
||||||
θ value | θ > 10 (rank : 152) | NC score | 0.052414 (rank : 336) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 350 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9NYB9, Q13147, Q13249, Q13801, Q9BV70 | Gene names | ABI2, ARGBPIA | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1). |
ABI2_MOUSE
|
||||||
θ value | θ > 10 (rank : 153) | NC score | 0.051542 (rank : 343) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 266 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P62484, Q6PHU3 | Gene names | Abi2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Abl interactor 2 (Abelson interactor 2) (Abi-2). |
ABI3_HUMAN
|
||||||
θ value | θ > 10 (rank : 154) | NC score | 0.055062 (rank : 316) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q9P2A4, Q9H0P6 | Gene names | ABI3, NESH | |||
Domain Architecture |
No domain graphic available |
|||||
Description | ABI gene family member 3 (New molecule including SH3) (Nesh). |
ABI3_MOUSE
|
||||||
θ value | θ > 10 (rank : 155) | NC score | 0.050504 (rank : 355) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q8BYZ1, Q6PE63, Q9D7S4 | Gene names | Abi3, Nesh | |||
Domain Architecture |
No domain graphic available |
|||||
Description | ABI gene family member 3 (New molecule including SH3) (Nesh). |
ACK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 156) | NC score | 0.068536 (rank : 162) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1140 | Shared Neighborhood Hits | 46 | |
SwissProt Accessions | Q07912, Q8N6U7, Q96H59 | Gene names | TNK2, ACK1 | |||
Domain Architecture |
|
|||||
Description | Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2). |
ACK1_MOUSE
|
||||||
θ value | θ > 10 (rank : 157) | NC score | 0.068925 (rank : 160) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1080 | Shared Neighborhood Hits | 47 | |
SwissProt Accessions | O54967, Q8C2U0, Q8K0K4 | Gene names | Tnk2, Ack1 | |||
Domain Architecture |
|
|||||
Description | Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2). |
AHI1_MOUSE
|
||||||
θ value | θ > 10 (rank : 158) | NC score | 0.051890 (rank : 338) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 496 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q8K3E5, Q7TNV2, Q9CVY1 | Gene names | Ahi1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Jouberin (Abelson helper integration site 1 protein) (AHI-1). |
ALK_HUMAN
|
||||||
θ value | θ > 10 (rank : 159) | NC score | 0.069433 (rank : 157) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 795 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q9UM73, Q9Y4K6 | Gene names | ALK | |||
Domain Architecture |
|
|||||
Description | ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen). |
ALK_MOUSE
|
||||||
θ value | θ > 10 (rank : 160) | NC score | 0.069851 (rank : 156) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 811 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P97793 | Gene names | Alk | |||
Domain Architecture |
|
|||||
Description | ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen). |
ANPRA_HUMAN
|
||||||
θ value | θ > 10 (rank : 161) | NC score | 0.056196 (rank : 309) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 612 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P16066, Q6P4Q3 | Gene names | NPR1, ANPRA | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor). |
ANPRA_MOUSE
|
||||||
θ value | θ > 10 (rank : 162) | NC score | 0.055654 (rank : 315) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 600 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P18293 | Gene names | Npr1, Npra | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor). |
ANPRB_HUMAN
|
||||||
θ value | θ > 10 (rank : 163) | NC score | 0.051859 (rank : 339) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 646 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P20594, O60871, Q9UQ50 | Gene names | NPR2, ANPRB | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor). |
ANPRB_MOUSE
|
||||||
θ value | θ > 10 (rank : 164) | NC score | 0.052015 (rank : 337) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 607 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9 | Gene names | Npr2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor). |
ARHG4_HUMAN
|
||||||
θ value | θ > 10 (rank : 165) | NC score | 0.051469 (rank : 344) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 242 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q9NR80, Q9HDC6, Q9UPP0 | Gene names | ARHGEF4, KIAA1112 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef). |
ARHG6_HUMAN
|
||||||
θ value | θ > 10 (rank : 166) | NC score | 0.060761 (rank : 260) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 376 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q15052, Q15396, Q5JQ66, Q86XH0 | Gene names | ARHGEF6, COOL2, KIAA0006, PIXA | |||
Domain Architecture |
|
|||||
Description | Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2). |
ARHG6_MOUSE
|
||||||
θ value | θ > 10 (rank : 167) | NC score | 0.059576 (rank : 275) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 394 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8K4I3, Q8C9V4 | Gene names | Arhgef6 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6). |
ARHG7_HUMAN
|
||||||
θ value | θ > 10 (rank : 168) | NC score | 0.062432 (rank : 244) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 347 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1 | Gene names | ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85). |
ARHG7_MOUSE
|
||||||
θ value | θ > 10 (rank : 169) | NC score | 0.063194 (rank : 230) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 396 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q9ES28, O08757, Q9ES27 | Gene names | Arhgef7, Pak3bp | |||
Domain Architecture |
|
|||||
Description | Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR). |
BLK_HUMAN
|
||||||
θ value | θ > 10 (rank : 170) | NC score | 0.105466 (rank : 125) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 994 | Shared Neighborhood Hits | 74 | |
SwissProt Accessions | P51451, Q16291 | Gene names | BLK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK). |
BLK_MOUSE
|
||||||
θ value | θ > 10 (rank : 171) | NC score | 0.110798 (rank : 115) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 992 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P16277 | Gene names | Blk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK). |
BLNK_HUMAN
|
||||||
θ value | θ > 10 (rank : 172) | NC score | 0.093922 (rank : 134) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 228 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q8WV28, O75498, O75499 | Gene names | BLNK, BASH, SLP65 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65). |
BRAF1_HUMAN
|
||||||
θ value | θ > 10 (rank : 173) | NC score | 0.050672 (rank : 350) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 883 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | P15056, Q13878, Q9Y6T3 | Gene names | BRAF, BRAF1, RAFB1 | |||
Domain Architecture |
|
|||||
Description | B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1). |
BTK_HUMAN
|
||||||
θ value | θ > 10 (rank : 174) | NC score | 0.107285 (rank : 120) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 74 | |
SwissProt Accessions | Q06187 | Gene names | BTK, AGMX1, ATK, BPK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK). |
BTK_MOUSE
|
||||||
θ value | θ > 10 (rank : 175) | NC score | 0.106874 (rank : 121) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1017 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P35991, Q61365 | Gene names | Btk, Bpk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB). |
CD2AP_HUMAN
|
||||||
θ value | θ > 10 (rank : 176) | NC score | 0.075638 (rank : 141) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 315 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9Y5K6, Q9UG97 | Gene names | CD2AP | |||
Domain Architecture |
|
|||||
Description | CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS). |
CD2AP_MOUSE
|
||||||
θ value | θ > 10 (rank : 177) | NC score | 0.072009 (rank : 146) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 336 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9JLQ0, O88903, Q8K4Z1, Q8VCI9 | Gene names | Cd2ap, Mets1 | |||
Domain Architecture |
|
|||||
Description | CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1). |
CIP4_HUMAN
|
||||||
θ value | θ > 10 (rank : 178) | NC score | 0.052461 (rank : 335) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 374 | Shared Neighborhood Hits | 22 | |
SwissProt Accessions | Q15642, O15184, Q5TZN1 | Gene names | TRIP10, CIP4 | |||
Domain Architecture |
|
|||||
Description | Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10). |
CISH_HUMAN
|
||||||
θ value | θ > 10 (rank : 179) | NC score | 0.096727 (rank : 132) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 48 | |
SwissProt Accessions | Q9NSE2, Q9NS38, Q9Y5R1 | Gene names | CISH, G18 | |||
Domain Architecture |
|
|||||
Description | Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18). |
CISH_MOUSE
|
||||||
θ value | θ > 10 (rank : 180) | NC score | 0.095425 (rank : 133) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q62225, Q3TC70 | Gene names | Cish, Cis | |||
Domain Architecture |
|
|||||
Description | Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS). |
CSF1R_HUMAN
|
||||||
θ value | θ > 10 (rank : 181) | NC score | 0.064921 (rank : 196) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 943 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P07333, Q6LDW5, Q6LDY4 | Gene names | CSF1R, FMS | |||
Domain Architecture |
|
|||||
Description | Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen). |
CSF1R_MOUSE
|
||||||
θ value | θ > 10 (rank : 182) | NC score | 0.064241 (rank : 211) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 983 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P09581, Q3U3P1, Q9DBH9 | Gene names | Csf1r, Csfmr, Fms | |||
Domain Architecture |
|
|||||
Description | Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen). |
CT032_HUMAN
|
||||||
θ value | θ > 10 (rank : 183) | NC score | 0.051567 (rank : 342) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 235 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9NQ75, Q96K09, Q9BYL5 | Gene names | HEFL, C20orf32 | |||
Domain Architecture |
|
|||||
Description | HEF-like protein. |
DDR1_HUMAN
|
||||||
θ value | θ > 10 (rank : 184) | NC score | 0.064964 (rank : 195) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 819 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q08345, Q14196, Q16562, Q5ST12, Q9UD37 | Gene names | DDR1, CAK, EDDR1, RTK6, TRKE | |||
Domain Architecture |
|
|||||
Description | Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen). |
DDR1_MOUSE
|
||||||
θ value | θ > 10 (rank : 185) | NC score | 0.065126 (rank : 192) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 818 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q03146 | Gene names | Ddr1, Cak, Eddr1, Mpk6 | |||
Domain Architecture |
|
|||||
Description | Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen). |
DDR2_HUMAN
|
||||||
θ value | θ > 10 (rank : 186) | NC score | 0.063311 (rank : 227) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 818 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q16832 | Gene names | DDR2, NTRKR3, TKT, TYRO10 | |||
Domain Architecture |
|
|||||
Description | Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen). |
DDR2_MOUSE
|
||||||
θ value | θ > 10 (rank : 187) | NC score | 0.063249 (rank : 228) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 813 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q62371 | Gene names | Ddr2, Ntrkr3, Tkt, Tyro10 | |||
Domain Architecture |
|
|||||
Description | Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen). |
DNMBP_HUMAN
|
||||||
θ value | θ > 10 (rank : 188) | NC score | 0.068248 (rank : 163) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 413 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q6XZF7, Q8IVY3, Q9Y2L3 | Gene names | DNMBP, KIAA1010 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Dynamin-binding protein (Scaffold protein Tuba). |
DNMBP_MOUSE
|
||||||
θ value | θ > 10 (rank : 189) | NC score | 0.065943 (rank : 183) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 435 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2 | Gene names | Dnmbp, Kiaa1010 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Dynamin-binding protein (Scaffold protein Tuba). |
EGFR_HUMAN
|
||||||
θ value | θ > 10 (rank : 190) | NC score | 0.062796 (rank : 241) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 939 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5 | Gene names | EGFR, ERBB1 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1). |
EGFR_MOUSE
|
||||||
θ value | θ > 10 (rank : 191) | NC score | 0.063021 (rank : 236) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 927 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q01279 | Gene names | Egfr | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor precursor (EC 2.7.10.1). |
EPHA1_HUMAN
|
||||||
θ value | θ > 10 (rank : 192) | NC score | 0.061545 (rank : 252) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 997 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P21709, Q15405 | Gene names | EPHA1, EPH, EPHT, EPHT1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH). |
EPHA1_MOUSE
|
||||||
θ value | θ > 10 (rank : 193) | NC score | 0.062459 (rank : 243) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 958 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q60750, Q8CED9, Q9ESJ2 | Gene names | Epha1, Esk | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK). |
EPHA2_HUMAN
|
||||||
θ value | θ > 10 (rank : 194) | NC score | 0.060257 (rank : 266) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1021 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29317 | Gene names | EPHA2, ECK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase). |
EPHA2_MOUSE
|
||||||
θ value | θ > 10 (rank : 195) | NC score | 0.059783 (rank : 273) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1020 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q03145, Q60633, Q62212 | Gene names | Epha2, Eck, Sek2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2). |
EPHA3_HUMAN
|
||||||
θ value | θ > 10 (rank : 196) | NC score | 0.058559 (rank : 293) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1005 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29320, Q9H2V3, Q9H2V4 | Gene names | EPHA3, ETK, ETK1, HEK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4). |
EPHA3_MOUSE
|
||||||
θ value | θ > 10 (rank : 197) | NC score | 0.058795 (rank : 289) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29319 | Gene names | Epha3, Etk1, Mek4, Tyro4 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4). |
EPHA4_HUMAN
|
||||||
θ value | θ > 10 (rank : 198) | NC score | 0.058830 (rank : 287) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 975 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54764 | Gene names | EPHA4, HEK8, SEK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8). |
EPHA4_MOUSE
|
||||||
θ value | θ > 10 (rank : 199) | NC score | 0.058821 (rank : 288) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 982 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q03137 | Gene names | Epha4, Sek, Sek1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3). |
EPHA5_HUMAN
|
||||||
θ value | θ > 10 (rank : 200) | NC score | 0.058197 (rank : 295) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P54756 | Gene names | EPHA5, EHK1, HEK7 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7). |
EPHA5_MOUSE
|
||||||
θ value | θ > 10 (rank : 201) | NC score | 0.060772 (rank : 259) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 950 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q60629 | Gene names | Epha5, Bsk, Cek7, Ehk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7). |
EPHA6_HUMAN
|
||||||
θ value | θ > 10 (rank : 202) | NC score | 0.061477 (rank : 255) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 959 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9UF33 | Gene names | EPHA6, EHK2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2). |
EPHA6_MOUSE
|
||||||
θ value | θ > 10 (rank : 203) | NC score | 0.061326 (rank : 256) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 946 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q62413, Q8CCN2 | Gene names | Epha6, Ehk-2, Ehk2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2). |
EPHA7_HUMAN
|
||||||
θ value | θ > 10 (rank : 204) | NC score | 0.058143 (rank : 296) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1053 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124 | Gene names | EPHA7, EHK3, HEK11 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11). |
EPHA7_MOUSE
|
||||||
θ value | θ > 10 (rank : 205) | NC score | 0.058053 (rank : 298) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1025 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q61772, Q61505, Q61773, Q61774 | Gene names | Epha7, Ebk, Ehk3, Mdk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1). |
EPHA8_HUMAN
|
||||||
θ value | θ > 10 (rank : 206) | NC score | 0.059507 (rank : 276) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 956 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29322, Q9NUA9, Q9P269 | Gene names | EPHA8, EEK, KIAA1459 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3). |
EPHA8_MOUSE
|
||||||
θ value | θ > 10 (rank : 207) | NC score | 0.059659 (rank : 274) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 969 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O09127 | Gene names | Epha8, Eek | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase). |
EPHAA_HUMAN
|
||||||
θ value | θ > 10 (rank : 208) | NC score | 0.064993 (rank : 194) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 960 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q5JZY3, Q6NW42 | Gene names | EPHA10 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Ephrin type-A receptor 10 precursor (EC 2.7.10.1). |
EPHB1_HUMAN
|
||||||
θ value | θ > 10 (rank : 209) | NC score | 0.058578 (rank : 292) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P54762, O43569, O95142, O95143 | Gene names | EPHB1, EPHT2, NET | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK). |
EPHB2_HUMAN
|
||||||
θ value | θ > 10 (rank : 210) | NC score | 0.058833 (rank : 286) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 983 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8 | Gene names | EPHB2, DRT, EPTH3, ERK, HEK5 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen). |
EPHB2_MOUSE
|
||||||
θ value | θ > 10 (rank : 211) | NC score | 0.058851 (rank : 284) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 982 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54763, Q62213, Q9QVY4 | Gene names | Ephb2, Epth3, Nuk, Sek3 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3). |
EPHB3_HUMAN
|
||||||
θ value | θ > 10 (rank : 212) | NC score | 0.059384 (rank : 278) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 996 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54753, Q7Z740 | Gene names | EPHB3, ETK2, HEK2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2). |
EPHB3_MOUSE
|
||||||
θ value | θ > 10 (rank : 213) | NC score | 0.059417 (rank : 277) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 996 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54754, Q62214 | Gene names | Ephb3, Etk2, Mdk5, Sek4 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4). |
EPHB4_HUMAN
|
||||||
θ value | θ > 10 (rank : 214) | NC score | 0.059353 (rank : 279) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1056 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P54760, Q9BTA5, Q9BXP0 | Gene names | EPHB4, HTK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK). |
EPHB4_MOUSE
|
||||||
θ value | θ > 10 (rank : 215) | NC score | 0.058661 (rank : 290) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1013 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54761, Q60627 | Gene names | Ephb4, Htk, Mdk2, Myk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1). |
EPHB6_HUMAN
|
||||||
θ value | θ > 10 (rank : 216) | NC score | 0.064191 (rank : 213) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 912 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | O15197 | Gene names | EPHB6 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP). |
EPHB6_MOUSE
|
||||||
θ value | θ > 10 (rank : 217) | NC score | 0.064004 (rank : 218) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 906 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O08644, Q8BN76, Q8K0A9 | Gene names | Ephb6, Cekl | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP). |
EPS8_HUMAN
|
||||||
θ value | θ > 10 (rank : 218) | NC score | 0.054651 (rank : 319) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q12929, Q8N6J0 | Gene names | EPS8 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor kinase substrate 8. |
EPS8_MOUSE
|
||||||
θ value | θ > 10 (rank : 219) | NC score | 0.051378 (rank : 345) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 157 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q08509 | Gene names | Eps8 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor kinase substrate 8. |
ERBB2_HUMAN
|
||||||
θ value | θ > 10 (rank : 220) | NC score | 0.065031 (rank : 193) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1073 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | P04626, Q14256, Q6LDV1, Q9UMK4 | Gene names | ERBB2, HER2, NEU, NGL | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19). |
ERBB2_MOUSE
|
||||||
θ value | θ > 10 (rank : 221) | NC score | 0.064333 (rank : 208) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 918 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P70424, Q61525, Q6ZPE0 | Gene names | Erbb2, Kiaa3023, Neu | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene). |
ERBB3_HUMAN
|
||||||
θ value | θ > 10 (rank : 222) | NC score | 0.064357 (rank : 207) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 918 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P21860 | Gene names | ERBB3, HER3 | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3). |
ERBB3_MOUSE
|
||||||
θ value | θ > 10 (rank : 223) | NC score | 0.064566 (rank : 203) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 898 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317 | Gene names | Erbb3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor). |
ERBB4_HUMAN
|
||||||
θ value | θ > 10 (rank : 224) | NC score | 0.064239 (rank : 212) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 910 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q15303 | Gene names | ERBB4, HER4 | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4). |
ES8L2_HUMAN
|
||||||
θ value | θ > 10 (rank : 225) | NC score | 0.050023 (rank : 357) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 193 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9 | Gene names | EPS8L2, EPS8R2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2). |
ES8L3_MOUSE
|
||||||
θ value | θ > 10 (rank : 226) | NC score | 0.051637 (rank : 341) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 168 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q91WL0, Q3TJ14 | Gene names | Eps8l3, Eps8r3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3). |
FAK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 227) | NC score | 0.064290 (rank : 210) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q05397, Q14291, Q9UD85 | Gene names | PTK2, FAK, FAK1 | |||
Domain Architecture |
|
|||||
Description | Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2). |
FAK1_MOUSE
|
||||||
θ value | θ > 10 (rank : 228) | NC score | 0.064326 (rank : 209) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P34152, O08578 | Gene names | Ptk2, Fadk, Fak, Fak1 | |||
Domain Architecture |
|
|||||
Description | Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK). |
FAK2_HUMAN
|
||||||
θ value | θ > 10 (rank : 229) | NC score | 0.066504 (rank : 177) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q14289, Q13475, Q14290, Q16709 | Gene names | PTK2B, FAK2, PYK2, RAFTK | |||
Domain Architecture |
|
|||||
Description | Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK). |
FAK2_MOUSE
|
||||||
θ value | θ > 10 (rank : 230) | NC score | 0.065957 (rank : 182) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 851 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9QVP9 | Gene names | Ptk2b, Fak2, Pyk2, Raftk | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK). |
FGFR1_HUMAN
|
||||||
θ value | θ > 10 (rank : 231) | NC score | 0.060592 (rank : 262) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1069 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685 | Gene names | FGFR1, FGFBR, FLG, FLT2 | |||
Domain Architecture |
|
|||||
Description | Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen). |
FGFR1_MOUSE
|
||||||
θ value | θ > 10 (rank : 232) | NC score | 0.060620 (rank : 261) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1068 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P16092, Q01736, Q61562, Q80T10 | Gene names | Fgfr1, Flg | |||
Domain Architecture |
|
|||||
Description | Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen). |
FGFR2_HUMAN
|
||||||
θ value | θ > 10 (rank : 233) | NC score | 0.060900 (rank : 258) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1062 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0 | Gene names | FGFR2, BEK, KSAM | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen). |
FGFR2_MOUSE
|
||||||
θ value | θ > 10 (rank : 234) | NC score | 0.061073 (rank : 257) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1062 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P21803, O55141, Q00389, Q61342 | Gene names | Fgfr2, Bek, Ect1 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen). |
FGFR3_HUMAN
|
||||||
θ value | θ > 10 (rank : 235) | NC score | 0.061794 (rank : 251) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1042 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P22607, Q14308, Q16294, Q16608 | Gene names | FGFR3, JTK4 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). |
FGFR3_MOUSE
|
||||||
θ value | θ > 10 (rank : 236) | NC score | 0.061526 (rank : 254) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1059 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q61851, Q61564, Q63834 | Gene names | Fgfr3, Mfr3, Sam3 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen). |
FGFR4_HUMAN
|
||||||
θ value | θ > 10 (rank : 237) | NC score | 0.063080 (rank : 233) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1037 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P22455, O43785, Q14309 | Gene names | FGFR4, JTK2, TKF | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen). |
FGFR4_MOUSE
|
||||||
θ value | θ > 10 (rank : 238) | NC score | 0.064189 (rank : 214) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q03142, Q5J7D9, Q8C3V5, Q8CIB8 | Gene names | Fgfr4, Fgfr-4, Mpk-11 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen). |
FGR_HUMAN
|
||||||
θ value | θ > 10 (rank : 239) | NC score | 0.129075 (rank : 95) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1067 | Shared Neighborhood Hits | 96 | |
SwissProt Accessions | P09769, Q9UIQ3 | Gene names | FGR, SRC2 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR). |
FLT3_HUMAN
|
||||||
θ value | θ > 10 (rank : 240) | NC score | 0.065935 (rank : 184) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 843 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P36888, Q13414 | Gene names | FLT3, STK1 | |||
Domain Architecture |
|
|||||
Description | FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen). |
FLT3_MOUSE
|
||||||
θ value | θ > 10 (rank : 241) | NC score | 0.066239 (rank : 180) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q00342 | Gene names | Flt3, Flk-2, Flt-3 | |||
Domain Architecture |
|
|||||
Description | FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen). |
FRK_HUMAN
|
||||||
θ value | θ > 10 (rank : 242) | NC score | 0.127958 (rank : 96) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1058 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P42685, Q13128 | Gene names | FRK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK). |
FYN_HUMAN
|
||||||
θ value | θ > 10 (rank : 243) | NC score | 0.120247 (rank : 107) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1078 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P06241 | Gene names | FYN | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK). |
FYN_MOUSE
|
||||||
θ value | θ > 10 (rank : 244) | NC score | 0.120651 (rank : 106) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1073 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | P39688 | Gene names | Fyn | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn). |
GRB10_HUMAN
|
||||||
θ value | θ > 10 (rank : 245) | NC score | 0.237392 (rank : 51) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 147 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948 | Gene names | GRB10, GRBIR, KIAA0207 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR). |
GRB10_MOUSE
|
||||||
θ value | θ > 10 (rank : 246) | NC score | 0.238673 (rank : 50) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 156 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5 | Gene names | Grb10 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 10 (GRB10 adaptor protein). |
GUC2C_HUMAN
|
||||||
θ value | θ > 10 (rank : 247) | NC score | 0.053461 (rank : 327) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 624 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P25092 | Gene names | GUCY2C, GUC2C, STAR | |||
Domain Architecture |
|
|||||
Description | Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR). |
GUC2F_HUMAN
|
||||||
θ value | θ > 10 (rank : 248) | NC score | 0.055683 (rank : 314) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 740 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P51841, Q9UJF1 | Gene names | GUCY2F, GUC2F, RETGC2 | |||
Domain Architecture |
|
|||||
Description | Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F). |
HCK_HUMAN
|
||||||
θ value | θ > 10 (rank : 249) | NC score | 0.111228 (rank : 114) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1035 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5 | Gene names | HCK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase). |
HCK_MOUSE
|
||||||
θ value | θ > 10 (rank : 250) | NC score | 0.110274 (rank : 116) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1029 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | P08103 | Gene names | Hck | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK). |
HCLS1_HUMAN
|
||||||
θ value | θ > 10 (rank : 251) | NC score | 0.060173 (rank : 268) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 358 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | P14317 | Gene names | HCLS1, HS1 | |||
Domain Architecture |
|
|||||
Description | Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75). |
HCLS1_MOUSE
|
||||||
θ value | θ > 10 (rank : 252) | NC score | 0.060014 (rank : 272) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 329 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | P49710 | Gene names | Hcls1, Hs1 | |||
Domain Architecture |
|
|||||
Description | Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1). |
IGF1R_HUMAN
|
||||||
θ value | θ > 10 (rank : 253) | NC score | 0.065513 (rank : 188) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 977 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P08069 | Gene names | IGF1R | |||
Domain Architecture |
|
|||||
Description | Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]. |
IGF1R_MOUSE
|
||||||
θ value | θ > 10 (rank : 254) | NC score | 0.065528 (rank : 186) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 973 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q60751, O70438, Q62123 | Gene names | Igf1r | |||
Domain Architecture |
|
|||||
Description | Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]. |
ILK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 255) | NC score | 0.053547 (rank : 326) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 857 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q13418 | Gene names | ILK, ILK1 | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK). |
ILK2_HUMAN
|
||||||
θ value | θ > 10 (rank : 256) | NC score | 0.053053 (rank : 330) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 848 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P57043 | Gene names | ILK2 | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2). |
ILK_MOUSE
|
||||||
θ value | θ > 10 (rank : 257) | NC score | 0.054063 (rank : 322) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 858 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | O55222 | Gene names | Ilk | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase (EC 2.7.11.1). |
INSRR_HUMAN
|
||||||
θ value | θ > 10 (rank : 258) | NC score | 0.064549 (rank : 204) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 950 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P14616, O60724 | Gene names | INSRR, IRR | |||
Domain Architecture |
|
|||||
Description | Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]. |
INSRR_MOUSE
|
||||||
θ value | θ > 10 (rank : 259) | NC score | 0.064581 (rank : 202) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 961 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q9WTL4 | Gene names | Insrr, Irr | |||
Domain Architecture |
|
|||||
Description | Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]. |
INSR_HUMAN
|
||||||
θ value | θ > 10 (rank : 260) | NC score | 0.063506 (rank : 224) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 963 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P06213 | Gene names | INSR | |||
Domain Architecture |
|
|||||
Description | Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta]. |
INSR_MOUSE
|
||||||
θ value | θ > 10 (rank : 261) | NC score | 0.063060 (rank : 234) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 968 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P15208 | Gene names | Insr | |||
Domain Architecture |
|
|||||
Description | Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta]. |
ITK_HUMAN
|
||||||
θ value | θ > 10 (rank : 262) | NC score | 0.105799 (rank : 123) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1016 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | Q08881 | Gene names | ITK, EMT, LYK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT). |
ITK_MOUSE
|
||||||
θ value | θ > 10 (rank : 263) | NC score | 0.105031 (rank : 126) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 985 | Shared Neighborhood Hits | 78 | |
SwissProt Accessions | Q03526 | Gene names | Itk, Emt, Tlk, Tsk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK). |
ITSN2_HUMAN
|
||||||
θ value | θ > 10 (rank : 264) | NC score | 0.050602 (rank : 351) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1173 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4 | Gene names | ITSN2, KIAA1256, SH3D1B, SWAP | |||
Domain Architecture |
|
|||||
Description | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein). |
JAK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 265) | NC score | 0.057804 (rank : 300) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 858 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P23458 | Gene names | JAK1, JAK1A | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1). |
JAK1_MOUSE
|
||||||
θ value | θ > 10 (rank : 266) | NC score | 0.058650 (rank : 291) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 854 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P52332, Q62126 | Gene names | Jak1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1). |
JAK2_HUMAN
|
||||||
θ value | θ > 10 (rank : 267) | NC score | 0.054461 (rank : 320) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | O60674, O14636, O75297 | Gene names | JAK2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2). |
JAK2_MOUSE
|
||||||
θ value | θ > 10 (rank : 268) | NC score | 0.054953 (rank : 317) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 839 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q62120, Q62124 | Gene names | Jak2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2). |
JAK3_HUMAN
|
||||||
θ value | θ > 10 (rank : 269) | NC score | 0.056206 (rank : 308) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 827 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P52333, Q13259, Q13260, Q13611, Q9Y6S2 | Gene names | JAK3 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK). |
JAK3_MOUSE
|
||||||
θ value | θ > 10 (rank : 270) | NC score | 0.053669 (rank : 325) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 821 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q62137, Q61746, Q61747 | Gene names | Jak3 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3). |
KIT_HUMAN
|
||||||
θ value | θ > 10 (rank : 271) | NC score | 0.064415 (rank : 206) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 953 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P10721, Q9UM99 | Gene names | KIT | |||
Domain Architecture |
|
|||||
Description | Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen). |
KIT_MOUSE
|
||||||
θ value | θ > 10 (rank : 272) | NC score | 0.064503 (rank : 205) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 949 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P05532, Q61415, Q61416, Q61417, Q6LEE9 | Gene names | Kit, Sl | |||
Domain Architecture |
|
|||||
Description | Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen). |
KSR1_HUMAN
|
||||||
θ value | θ > 10 (rank : 273) | NC score | 0.051013 (rank : 348) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 867 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q8IVT5, Q13476 | Gene names | KSR1, KSR | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Kinase suppressor of ras-1 (Kinase suppressor of ras). |
KSR2_HUMAN
|
||||||
θ value | θ > 10 (rank : 274) | NC score | 0.051281 (rank : 347) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 920 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q6VAB6, Q8N775 | Gene names | KSR2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Kinase suppressor of ras-2 (hKSR2). |
LTK_HUMAN
|
||||||
θ value | θ > 10 (rank : 275) | NC score | 0.070957 (rank : 152) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 774 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P29376 | Gene names | LTK, TYK1 | |||
Domain Architecture |
|
|||||
Description | Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1). |
LTK_MOUSE
|
||||||
θ value | θ > 10 (rank : 276) | NC score | 0.070105 (rank : 153) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 770 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P08923 | Gene names | Ltk | |||
Domain Architecture |
|
|||||
Description | Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1). |
LYN_HUMAN
|
||||||
θ value | θ > 10 (rank : 277) | NC score | 0.105505 (rank : 124) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1022 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | P07948 | Gene names | LYN | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Lyn (EC 2.7.10.2). |
LYN_MOUSE
|
||||||
θ value | θ > 10 (rank : 278) | NC score | 0.106684 (rank : 122) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1023 | Shared Neighborhood Hits | 84 | |
SwissProt Accessions | P25911, Q62127 | Gene names | Lyn | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Lyn (EC 2.7.10.2). |
M3K10_HUMAN
|
||||||
θ value | θ > 10 (rank : 279) | NC score | 0.062716 (rank : 242) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1071 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q02779, Q12761, Q14871 | Gene names | MAP3K10, MLK2, MST | |||
Domain Architecture |
|
|||||
Description | Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST). |
M3K11_HUMAN
|
||||||
θ value | θ > 10 (rank : 280) | NC score | 0.065521 (rank : 187) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1136 | Shared Neighborhood Hits | 55 | |
SwissProt Accessions | Q16584, Q6P2G4 | Gene names | MAP3K11, MLK3, SPRK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase). |
M3K9_HUMAN
|
||||||
θ value | θ > 10 (rank : 281) | NC score | 0.063636 (rank : 222) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1123 | Shared Neighborhood Hits | 52 | |
SwissProt Accessions | P80192, Q6EH31, Q9H2N5 | Gene names | MAP3K9, MLK1, PRKE1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1). |
M3KL4_HUMAN
|
||||||
θ value | θ > 10 (rank : 282) | NC score | 0.066344 (rank : 178) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1087 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1 | Gene names | MLK4, KIAA1804 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4). |
MERTK_HUMAN
|
||||||
θ value | θ > 10 (rank : 283) | NC score | 0.067244 (rank : 170) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q12866, Q9HBB4 | Gene names | MERTK, MER | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). |
MERTK_MOUSE
|
||||||
θ value | θ > 10 (rank : 284) | NC score | 0.066507 (rank : 176) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 974 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q60805, Q62194 | Gene names | Mertk, Mer | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). |
MET_HUMAN
|
||||||
θ value | θ > 10 (rank : 285) | NC score | 0.062125 (rank : 248) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 831 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P08581, O60366, Q12875, Q9UDX7, Q9UPL8 | Gene names | MET | |||
Domain Architecture |
|
|||||
Description | Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met). |
MET_MOUSE
|
||||||
θ value | θ > 10 (rank : 286) | NC score | 0.062413 (rank : 245) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 844 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P16056, Q62125 | Gene names | Met | |||
Domain Architecture |
|
|||||
Description | Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met). |
MLKL_HUMAN
|
||||||
θ value | θ > 10 (rank : 287) | NC score | 0.062185 (rank : 247) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 600 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q8NB16, Q8N6V0 | Gene names | MLKL | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mixed lineage kinase domain-like protein. |
MLKL_MOUSE
|
||||||
θ value | θ > 10 (rank : 288) | NC score | 0.060176 (rank : 267) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 707 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9D2Y4, Q8CIJ5 | Gene names | Mlkl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mixed lineage kinase domain-like protein. |
MLTK_HUMAN
|
||||||
θ value | θ > 10 (rank : 289) | NC score | 0.050586 (rank : 352) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 911 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9 | Gene names | MLTK, ZAK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein). |
MLTK_MOUSE
|
||||||
θ value | θ > 10 (rank : 290) | NC score | 0.050533 (rank : 354) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 874 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3 | Gene names | Mltk | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK). |
MUSK_HUMAN
|
||||||
θ value | θ > 10 (rank : 291) | NC score | 0.061846 (rank : 250) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1074 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | O15146 | Gene names | MUSK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK). |
MUSK_MOUSE
|
||||||
θ value | θ > 10 (rank : 292) | NC score | 0.062302 (rank : 246) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1057 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q61006, Q61005, Q61987, Q61988 | Gene names | Musk, Nsk2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK). |
NCF1_HUMAN
|
||||||
θ value | θ > 10 (rank : 293) | NC score | 0.064010 (rank : 216) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 198 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2 | Gene names | NCF1 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2). |
NCF1_MOUSE
|
||||||
θ value | θ > 10 (rank : 294) | NC score | 0.063650 (rank : 221) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 198 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q09014, O70144, Q9JI34 | Gene names | Ncf1 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K). |
NCF2_HUMAN
|
||||||
θ value | θ > 10 (rank : 295) | NC score | 0.067852 (rank : 164) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 229 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P19878, Q2PP06, Q8NFC7, Q9BV51 | Gene names | NCF2 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2). |
NCF4_MOUSE
|
||||||
θ value | θ > 10 (rank : 296) | NC score | 0.050150 (rank : 356) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 177 | Shared Neighborhood Hits | 23 | |
SwissProt Accessions | P97369 | Gene names | Ncf4 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox). |
NPHP1_HUMAN
|
||||||
θ value | θ > 10 (rank : 297) | NC score | 0.083244 (rank : 139) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 288 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O15259, O14837 | Gene names | NPHP1, NPH1 | |||
Domain Architecture |
|
|||||
Description | Nephrocystin-1 (Juvenile nephronophthisis 1 protein). |
NPHP1_MOUSE
|
||||||
θ value | θ > 10 (rank : 298) | NC score | 0.086477 (rank : 138) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 267 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2 | Gene names | Nphp1, Nph1 | |||
Domain Architecture |
|
|||||
Description | Nephrocystin-1. |
NTRK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 299) | NC score | 0.064655 (rank : 200) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1023 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7 | Gene names | NTRK1, TRK | |||
Domain Architecture |
|
|||||
Description | High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A). |
NTRK2_HUMAN
|
||||||
θ value | θ > 10 (rank : 300) | NC score | 0.060515 (rank : 263) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1081 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q16620, Q16675, Q8WXJ6 | Gene names | NTRK2, TRKB | |||
Domain Architecture |
|
|||||
Description | BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B). |
NTRK2_MOUSE
|
||||||
θ value | θ > 10 (rank : 301) | NC score | 0.060506 (rank : 264) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1088 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P15209, Q3TUF9, Q80WU0, Q91XJ9 | Gene names | Ntrk2, Trkb | |||
Domain Architecture |
|
|||||
Description | BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B). |
NTRK3_HUMAN
|
||||||
θ value | θ > 10 (rank : 302) | NC score | 0.062929 (rank : 237) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1115 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q16288, Q12827, Q16289 | Gene names | NTRK3, TRKC | |||
Domain Architecture |
|
|||||
Description | NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C). |
OSTF1_HUMAN
|
||||||
θ value | θ > 10 (rank : 303) | NC score | 0.058378 (rank : 294) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 466 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q92882, Q5W126, Q96IJ4 | Gene names | OSTF1 | |||
Domain Architecture |
|
|||||
Description | Osteoclast-stimulating factor 1. |
OSTF1_MOUSE
|
||||||
θ value | θ > 10 (rank : 304) | NC score | 0.055943 (rank : 311) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 467 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q62422, Q3UF05 | Gene names | Ostf1, Sh3d3, Sh3p2 | |||
Domain Architecture |
|
|||||
Description | Osteoclast-stimulating factor 1 (SH3 domain protein 3). |
P55G_HUMAN
|
||||||
θ value | θ > 10 (rank : 305) | NC score | 0.150856 (rank : 80) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 451 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | Q92569, O60482 | Gene names | PIK3R3 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK). |
P55G_MOUSE
|
||||||
θ value | θ > 10 (rank : 306) | NC score | 0.146933 (rank : 84) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 401 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q64143 | Gene names | Pik3r3 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK). |
P85A_HUMAN
|
||||||
θ value | θ > 10 (rank : 307) | NC score | 0.157318 (rank : 79) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 479 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | P27986 | Gene names | PIK3R1, GRB1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K). |
P85A_MOUSE
|
||||||
θ value | θ > 10 (rank : 308) | NC score | 0.161354 (rank : 78) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 435 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P26450 | Gene names | Pik3r1 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K). |
P85B_MOUSE
|
||||||
θ value | θ > 10 (rank : 309) | NC score | 0.168702 (rank : 73) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 519 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | O08908 | Gene names | Pik3r2 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta). |
PACN1_HUMAN
|
||||||
θ value | θ > 10 (rank : 310) | NC score | 0.059098 (rank : 281) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 320 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9BY11, Q9P2G8 | Gene names | PACSIN1, KIAA1379 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 1. |
PACN1_MOUSE
|
||||||
θ value | θ > 10 (rank : 311) | NC score | 0.057285 (rank : 302) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 283 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q61644 | Gene names | Pacsin1, Pacsin | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 1. |
PACN2_HUMAN
|
||||||
θ value | θ > 10 (rank : 312) | NC score | 0.060077 (rank : 270) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 339 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2 | Gene names | PACSIN2 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 2. |
PACN2_MOUSE
|
||||||
θ value | θ > 10 (rank : 313) | NC score | 0.057135 (rank : 303) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 382 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | Q9WVE8 | Gene names | Pacsin2 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 2. |
PACN3_HUMAN
|
||||||
θ value | θ > 10 (rank : 314) | NC score | 0.055783 (rank : 312) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 385 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9UKS6, Q9H331, Q9NWV9 | Gene names | PACSIN3 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I). |
PACN3_MOUSE
|
||||||
θ value | θ > 10 (rank : 315) | NC score | 0.058075 (rank : 297) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 380 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q99JB8, Q9EQP9 | Gene names | Pacsin3 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase II substrate protein 3. |
PEX13_HUMAN
|
||||||
θ value | θ > 10 (rank : 316) | NC score | 0.056573 (rank : 306) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 128 | Shared Neighborhood Hits | 20 | |
SwissProt Accessions | Q92968 | Gene names | PEX13 | |||
Domain Architecture |
|
|||||
Description | Peroxisomal membrane protein PEX13 (Peroxin-13). |
PEX13_MOUSE
|
||||||
θ value | θ > 10 (rank : 317) | NC score | 0.051797 (rank : 340) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 19 | |
SwissProt Accessions | Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1 | Gene names | Pex13 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Peroxisomal membrane protein PEX13 (Peroxin-13). |
PGFRA_HUMAN
|
||||||
θ value | θ > 10 (rank : 318) | NC score | 0.063176 (rank : 231) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P16234, Q96KZ7 | Gene names | PDGFRA | |||
Domain Architecture |
|
|||||
Description | Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen). |
PGFRA_MOUSE
|
||||||
θ value | θ > 10 (rank : 319) | NC score | 0.063382 (rank : 225) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 975 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P26618, Q62046 | Gene names | Pdgfra | |||
Domain Architecture |
|
|||||
Description | Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen). |
PGFRB_HUMAN
|
||||||
θ value | θ > 10 (rank : 320) | NC score | 0.063738 (rank : 220) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 962 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P09619, Q8N5L4 | Gene names | PDGFRB | |||
Domain Architecture |
|
|||||
Description | Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen). |
PGFRB_MOUSE
|
||||||
θ value | θ > 10 (rank : 321) | NC score | 0.063612 (rank : 223) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 960 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P05622 | Gene names | Pdgfrb, Pdgfr | |||
Domain Architecture |
|
|||||
Description | Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen). |
PLCG1_HUMAN
|
||||||
θ value | θ > 10 (rank : 322) | NC score | 0.236532 (rank : 52) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 293 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P19174, Q2V575 | Gene names | PLCG1, PLC1 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148). |
PLCG1_MOUSE
|
||||||
θ value | θ > 10 (rank : 323) | NC score | 0.234748 (rank : 53) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 314 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | Q62077, Q6P1G1 | Gene names | Plcg1, Plcg-1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148). |
PPIP1_HUMAN
|
||||||
θ value | θ > 10 (rank : 324) | NC score | 0.067843 (rank : 165) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 389 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | O43586, O43585, O95657 | Gene names | PSTPIP1, CD2BP1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP). |
PPIP1_MOUSE
|
||||||
θ value | θ > 10 (rank : 325) | NC score | 0.064585 (rank : 201) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 377 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | P97814, Q4V9R4 | Gene names | Pstpip1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1). |
PTK7_HUMAN
|
||||||
θ value | θ > 10 (rank : 326) | NC score | 0.059272 (rank : 280) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q13308, Q13417 | Gene names | PTK7, CCK4 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4). |
RET_HUMAN
|
||||||
θ value | θ > 10 (rank : 327) | NC score | 0.063348 (rank : 226) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 873 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P07949, Q15250 | Gene names | RET | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret). |
RET_MOUSE
|
||||||
θ value | θ > 10 (rank : 328) | NC score | 0.062888 (rank : 239) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 884 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P35546, Q8BQ34, Q9QXH9 | Gene names | Ret | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret). |
RHG04_HUMAN
|
||||||
θ value | θ > 10 (rank : 329) | NC score | 0.053009 (rank : 331) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | P98171, Q14144 | Gene names | ARHGAP4, KIAA0131, RGC1, RHOGAP4 | |||
Domain Architecture |
|
|||||
Description | Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115). |
RON_HUMAN
|
||||||
θ value | θ > 10 (rank : 330) | NC score | 0.062823 (rank : 240) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 842 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q04912 | Gene names | MST1R, RON | |||
Domain Architecture |
|
|||||
Description | Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]. |
RON_MOUSE
|
||||||
θ value | θ > 10 (rank : 331) | NC score | 0.064014 (rank : 215) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 836 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q62190, Q62555 | Gene names | Mst1r, Ron, Stk | |||
Domain Architecture |
|
|||||
Description | Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]. |
ROR1_HUMAN
|
||||||
θ value | θ > 10 (rank : 332) | NC score | 0.062916 (rank : 238) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1018 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q01973, Q92776 | Gene names | ROR1, NTRKR1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1). |
ROR1_MOUSE
|
||||||
θ value | θ > 10 (rank : 333) | NC score | 0.063035 (rank : 235) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1025 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q9Z139 | Gene names | Ror1, Ntrkr1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1). |
ROR2_HUMAN
|
||||||
θ value | θ > 10 (rank : 334) | NC score | 0.063236 (rank : 229) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1014 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61 | Gene names | ROR2, NTRKR2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2). |
ROR2_MOUSE
|
||||||
θ value | θ > 10 (rank : 335) | NC score | 0.064704 (rank : 199) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1000 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9Z138 | Gene names | Ror2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2). |
ROS_HUMAN
|
||||||
θ value | θ > 10 (rank : 336) | NC score | 0.067372 (rank : 168) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 907 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P08922, Q15368 | Gene names | ROS1 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1). |
RYK_HUMAN
|
||||||
θ value | θ > 10 (rank : 337) | NC score | 0.072209 (rank : 145) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 701 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P34925, Q04696 | Gene names | RYK, JTK5A | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase RYK precursor (EC 2.7.10.1). |
RYK_MOUSE
|
||||||
θ value | θ > 10 (rank : 338) | NC score | 0.071648 (rank : 147) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 715 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q01887, Q61890 | Gene names | Ryk, Mrk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase). |
SH21A_HUMAN
|
||||||
θ value | θ > 10 (rank : 339) | NC score | 0.250337 (rank : 48) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 89 | Shared Neighborhood Hits | 60 | |
SwissProt Accessions | O60880, O95383, O95384, O95385, O95386, Q9UNR0 | Gene names | SH2D1A, DSHP, SAP | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein). |
SH21A_MOUSE
|
||||||
θ value | θ > 10 (rank : 340) | NC score | 0.251370 (rank : 47) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 89 | Shared Neighborhood Hits | 61 | |
SwissProt Accessions | O88890, Q9QWV6 | Gene names | Sh2d1a, Xlp | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP). |
SH3G1_HUMAN
|
||||||
θ value | θ > 10 (rank : 341) | NC score | 0.050866 (rank : 349) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q99961, Q99668 | Gene names | SH3GL1, CNSA1, SH3D2B | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL). |
SH3G1_MOUSE
|
||||||
θ value | θ > 10 (rank : 342) | NC score | 0.052616 (rank : 334) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 291 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q62419 | Gene names | Sh3gl1, Sh3d2b | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8). |
SH3G2_HUMAN
|
||||||
θ value | θ > 10 (rank : 343) | NC score | 0.053710 (rank : 324) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 324 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q99962, Q9NQK5 | Gene names | SH3GL2, CNSA2, SH3D2A | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1). |
SH3G3_HUMAN
|
||||||
θ value | θ > 10 (rank : 344) | NC score | 0.053084 (rank : 329) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 222 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q99963, O43553, O43554 | Gene names | SH3GL3, CNSA3, SH3D2C | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2). |
SH3G3_MOUSE
|
||||||
θ value | θ > 10 (rank : 345) | NC score | 0.054192 (rank : 321) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 236 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q62421 | Gene names | Sh3gl3, Sh3d2c, Sh3d2c2 | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13). |
SH3K1_HUMAN
|
||||||
θ value | θ > 10 (rank : 346) | NC score | 0.067431 (rank : 166) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 341 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0 | Gene names | SH3KBP1, CIN85 | |||
Domain Architecture |
|
|||||
Description | SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3). |
SH3K1_MOUSE
|
||||||
θ value | θ > 10 (rank : 347) | NC score | 0.066613 (rank : 175) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 332 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3 | Gene names | Sh3kbp1, Ruk, Seta | |||
Domain Architecture |
|
|||||
Description | SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk). |
SLAP1_HUMAN
|
||||||
θ value | θ > 10 (rank : 348) | NC score | 0.172108 (rank : 71) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 113 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | Q13239, Q9UMQ8 | Gene names | SLA, SLAP, SLAP1 | |||
Domain Architecture |
|
|||||
Description | SRC-like-adapter (Src-like-adapter protein 1) (hSLAP). |
SLAP1_MOUSE
|
||||||
θ value | θ > 10 (rank : 349) | NC score | 0.170353 (rank : 72) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 117 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8 | Gene names | Sla, Slap, Slap1 | |||
Domain Architecture |
|
|||||
Description | SRC-like-adapter (Src-like-adapter protein 1) (mSLAP). |
SLAP2_MOUSE
|
||||||
θ value | θ > 10 (rank : 350) | NC score | 0.183355 (rank : 67) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 136 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9 | Gene names | Sla2 | |||
Domain Architecture |
|
|||||
Description | Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2). |
SOCS1_HUMAN
|
||||||
θ value | θ > 10 (rank : 351) | NC score | 0.057486 (rank : 301) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 79 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O15524, O15097, Q9NSA7 | Gene names | SOCS1, SSI1, TIP3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3). |
SOCS1_MOUSE
|
||||||
θ value | θ > 10 (rank : 352) | NC score | 0.056184 (rank : 310) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 82 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O35716, O35960, Q3U3L0 | Gene names | Socs1, Cish1, Ssi1 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1). |
SOCS2_HUMAN
|
||||||
θ value | θ > 10 (rank : 353) | NC score | 0.138511 (rank : 88) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 104 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | O14508, O14542, O95102, Q9UKS5 | Gene names | SOCS2, CIS2, SSI2, STATI2 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2). |
SOCS2_MOUSE
|
||||||
θ value | θ > 10 (rank : 354) | NC score | 0.138990 (rank : 87) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | O35717 | Gene names | Socs2, Cis2, Cish2 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2). |
SOCS3_HUMAN
|
||||||
θ value | θ > 10 (rank : 355) | NC score | 0.071110 (rank : 150) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 77 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O14543, O14509 | Gene names | SOCS3, CIS3, SSI3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3). |
SOCS3_MOUSE
|
||||||
θ value | θ > 10 (rank : 356) | NC score | 0.069315 (rank : 158) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 72 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O35718, P97803, Q3U7X5 | Gene names | Socs3, Cis3, Cish3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10). |
SOCS4_HUMAN
|
||||||
θ value | θ > 10 (rank : 357) | NC score | 0.052788 (rank : 332) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 69 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q8WXH5 | Gene names | SOCS4, SOCS7 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7). |
SOCS4_MOUSE
|
||||||
θ value | θ > 10 (rank : 358) | NC score | 0.053355 (rank : 328) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 69 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q91ZA6 | Gene names | Socs4, Socs7 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7). |
SOCS7_MOUSE
|
||||||
θ value | θ > 10 (rank : 359) | NC score | 0.116880 (rank : 109) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 154 | Shared Neighborhood Hits | 58 | |
SwissProt Accessions | Q8VHQ2 | Gene names | Socs7, Cish7, Nap4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 7 (SOCS-7). |
SRBS1_HUMAN
|
||||||
θ value | θ > 10 (rank : 360) | NC score | 0.073765 (rank : 144) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 396 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338 | Gene names | SORBS1, KIAA1296, SH3D5 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12). |
SRBS1_MOUSE
|
||||||
θ value | θ > 10 (rank : 361) | NC score | 0.076661 (rank : 140) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 409 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9 | Gene names | Sorbs1, Kiaa1296, Sh3d5 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12). |
SRC8_HUMAN
|
||||||
θ value | θ > 10 (rank : 362) | NC score | 0.057885 (rank : 299) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 269 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q14247 | Gene names | CTTN, EMS1 | |||
Domain Architecture |
|
|||||
Description | Src substrate cortactin (Amplaxin) (Oncogene EMS1). |
SRC8_MOUSE
|
||||||
θ value | θ > 10 (rank : 363) | NC score | 0.056521 (rank : 307) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 292 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q60598 | Gene names | Cttn, Ems1 | |||
Domain Architecture |
|
|||||
Description | Src substrate cortactin. |
SRC_HUMAN
|
||||||
θ value | θ > 10 (rank : 364) | NC score | 0.127177 (rank : 100) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1058 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P12931, Q86VB9, Q9H5A8 | Gene names | SRC, SRC1 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). |
SRC_MOUSE
|
||||||
θ value | θ > 10 (rank : 365) | NC score | 0.127216 (rank : 99) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1033 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P05480 | Gene names | Src | |||
Domain Architecture |
|
|||||
Description | Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src). |
STAC3_HUMAN
|
||||||
θ value | θ > 10 (rank : 366) | NC score | 0.067205 (rank : 171) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 228 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q96MF2, Q96HU5 | Gene names | STAC3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH3 and cysteine-rich domain-containing protein 3. |
STAC3_MOUSE
|
||||||
θ value | θ > 10 (rank : 367) | NC score | 0.067145 (rank : 172) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 232 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8BZ71 | Gene names | Stac3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH3 and cysteine-rich domain-containing protein 3. |
STAC_HUMAN
|
||||||
θ value | θ > 10 (rank : 368) | NC score | 0.068735 (rank : 161) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 276 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q99469 | Gene names | STAC | |||
Domain Architecture |
|
|||||
Description | SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein). |
STAC_MOUSE
|
||||||
θ value | θ > 10 (rank : 369) | NC score | 0.071397 (rank : 149) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 268 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | P97306 | Gene names | Stac | |||
Domain Architecture |
|
|||||
Description | SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein). |
STAM1_HUMAN
|
||||||
θ value | θ > 10 (rank : 370) | NC score | 0.074397 (rank : 143) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 271 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q92783, Q8N6D9 | Gene names | STAM, STAM1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 1 (STAM-1). |
STAM1_MOUSE
|
||||||
θ value | θ > 10 (rank : 371) | NC score | 0.074465 (rank : 142) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 273 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | P70297 | Gene names | Stam, Stam1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 1 (STAM-1). |
STAM2_HUMAN
|
||||||
θ value | θ > 10 (rank : 372) | NC score | 0.068927 (rank : 159) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 288 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | O75886, Q7LDQ0, Q9UF58 | Gene names | STAM2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 2 (STAM-2). |
STAM2_MOUSE
|
||||||
θ value | θ > 10 (rank : 373) | NC score | 0.066276 (rank : 179) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 285 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O88811, Q8C8Y4 | Gene names | Stam2, Hbp | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein). |
STYK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 374) | NC score | 0.071599 (rank : 148) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 786 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q6J9G0, Q9BXY2, Q9NSH1 | Gene names | STYK1, NOK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique). |
STYK1_MOUSE
|
||||||
θ value | θ > 10 (rank : 375) | NC score | 0.071061 (rank : 151) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 779 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q6J9G1, Q8BZH6, Q8BZT1 | Gene names | Styk1, Nok | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK). |
TEC_HUMAN
|
||||||
θ value | θ > 10 (rank : 376) | NC score | 0.101934 (rank : 128) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1006 | Shared Neighborhood Hits | 69 | |
SwissProt Accessions | P42680 | Gene names | TEC, PSCTK4 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Tec (EC 2.7.10.2). |
TEC_MOUSE
|
||||||
θ value | θ > 10 (rank : 377) | NC score | 0.099293 (rank : 129) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1006 | Shared Neighborhood Hits | 65 | |
SwissProt Accessions | P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3 | Gene names | Tec | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Tec (EC 2.7.10.2). |
TENS1_HUMAN
|
||||||
θ value | θ > 10 (rank : 378) | NC score | 0.055698 (rank : 313) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 400 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | Q9HBL0 | Gene names | TNS1, TNS | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-1. |
TENS4_HUMAN
|
||||||
θ value | θ > 10 (rank : 379) | NC score | 0.063124 (rank : 232) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 214 | Shared Neighborhood Hits | 51 | |
SwissProt Accessions | Q8IZW8, Q71RB7, Q8WV64, Q96JV4 | Gene names | TNS4, CTEN | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-4 precursor (C-terminal tensin-like protein). |
TENS4_MOUSE
|
||||||
θ value | θ > 10 (rank : 380) | NC score | 0.066869 (rank : 173) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 54 | |
SwissProt Accessions | Q8BZ33, Q3TCM8, Q7TNR5 | Gene names | Tns4 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-4 precursor. |
TEX14_HUMAN
|
||||||
θ value | θ > 10 (rank : 381) | NC score | 0.051338 (rank : 346) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9 | Gene names | TEX14 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Testis-expressed protein 14 (Testis-expressed sequence 14). |
TEX14_MOUSE
|
||||||
θ value | θ > 10 (rank : 382) | NC score | 0.052695 (rank : 333) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1333 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8 | Gene names | Tex14 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Testis-expressed protein 14 (Testis-expressed sequence 14). |
TIE1_HUMAN
|
||||||
θ value | θ > 10 (rank : 383) | NC score | 0.062098 (rank : 249) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1241 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P35590 | Gene names | TIE1, TIE | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1). |
TIE1_MOUSE
|
||||||
θ value | θ > 10 (rank : 384) | NC score | 0.061534 (rank : 253) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1266 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q06806, Q811F4 | Gene names | Tie1, Tie, Tie-1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1). |
TIE2_HUMAN
|
||||||
θ value | θ > 10 (rank : 385) | NC score | 0.060169 (rank : 269) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1192 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q02763 | Gene names | TEK, TIE2 | |||
Domain Architecture |
|
|||||
Description | Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen). |
TIE2_MOUSE
|
||||||
θ value | θ > 10 (rank : 386) | NC score | 0.060304 (rank : 265) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1204 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q02858 | Gene names | Tek, Hyk, Tie-2, Tie2 | |||
Domain Architecture |
|
|||||
Description | Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen). |
TNK1_HUMAN
|
||||||
θ value | θ > 10 (rank : 387) | NC score | 0.065157 (rank : 190) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 815 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q13470, O95364, Q8IYI4 | Gene names | TNK1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1). |
TNK1_MOUSE
|
||||||
θ value | θ > 10 (rank : 388) | NC score | 0.064900 (rank : 197) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 806 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q99ML2, Q8CCC4, Q8K0X9, Q91V11 | Gene names | Tnk1, Kos1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells). |
TXK_HUMAN
|
||||||
θ value | θ > 10 (rank : 389) | NC score | 0.109062 (rank : 118) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 971 | Shared Neighborhood Hits | 77 | |
SwissProt Accessions | P42681, Q14220 | Gene names | TXK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase TXK (EC 2.7.10.2). |
TXK_MOUSE
|
||||||
θ value | θ > 10 (rank : 390) | NC score | 0.114373 (rank : 110) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P42682 | Gene names | Txk, Rlk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase). |
TYK2_HUMAN
|
||||||
θ value | θ > 10 (rank : 391) | NC score | 0.053946 (rank : 323) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 841 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P29597, Q6QB10, Q96CH0 | Gene names | TYK2 | |||
Domain Architecture |
|
|||||
Description | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2). |
TYK2_MOUSE
|
||||||
θ value | θ > 10 (rank : 392) | NC score | 0.054794 (rank : 318) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9R117, O88431, Q8VE41 | Gene names | Tyk2 | |||
Domain Architecture |
|
|||||
Description | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2). |
TYRO3_HUMAN
|
||||||
θ value | θ > 10 (rank : 393) | NC score | 0.063895 (rank : 219) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 995 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q06418, O14953, Q86VR3 | Gene names | TYRO3, BYK, DTK, RSE, SKY | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk). |
TYRO3_MOUSE
|
||||||
θ value | θ > 10 (rank : 394) | NC score | 0.064009 (rank : 217) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1007 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87 | Gene names | Tyro3, Dtk, Rse | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3). |
UFO_HUMAN
|
||||||
θ value | θ > 10 (rank : 395) | NC score | 0.065622 (rank : 185) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 981 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | P30530 | Gene names | AXL, UFO | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene). |
UFO_MOUSE
|
||||||
θ value | θ > 10 (rank : 396) | NC score | 0.064742 (rank : 198) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q00993 | Gene names | Axl, Ark, Ufo | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase). |
VAV_MOUSE
|
||||||
θ value | θ > 10 (rank : 397) | NC score | 0.191291 (rank : 66) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 430 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P27870, Q8BTV7 | Gene names | Vav1, Vav | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene vav (p95vav). |
VGFR1_HUMAN
|
||||||
θ value | θ > 10 (rank : 398) | NC score | 0.056883 (rank : 304) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1109 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P17948, O60722, P16057, Q12954 | Gene names | FLT1, FLT, FRT | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1). |
VGFR1_MOUSE
|
||||||
θ value | θ > 10 (rank : 399) | NC score | 0.056792 (rank : 305) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1118 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P35969, O55094, Q61517 | Gene names | Flt1, Emrk2, Flt | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2). |
VGFR2_HUMAN
|
||||||
θ value | θ > 10 (rank : 400) | NC score | 0.059014 (rank : 283) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P35968, O60723, Q14178 | Gene names | KDR, FLK1 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen). |
VGFR2_MOUSE
|
||||||
θ value | θ > 10 (rank : 401) | NC score | 0.058845 (rank : 285) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1089 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35918 | Gene names | Kdr, Flk-1, Flk1 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen). |
VGFR3_HUMAN
|
||||||
θ value | θ > 10 (rank : 402) | NC score | 0.060073 (rank : 271) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1037 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35916 | Gene names | FLT4 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4). |
VGFR3_MOUSE
|
||||||
θ value | θ > 10 (rank : 403) | NC score | 0.059066 (rank : 282) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1056 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35917 | Gene names | Flt4, Flt-4 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4). |
VINEX_HUMAN
|
||||||
θ value | θ > 10 (rank : 404) | NC score | 0.067276 (rank : 169) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 270 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | O60504, Q9UQE4 | Gene names | SORBS3, SCAM1 | |||
Domain Architecture |
|
|||||
Description | Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1). |
VINEX_MOUSE
|
||||||
θ value | θ > 10 (rank : 405) | NC score | 0.069936 (rank : 155) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 286 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9R1Z8, Q62423 | Gene names | Sorbs3, Scam1, Sh3d4 | |||
Domain Architecture |
|
|||||
Description | Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3). |
SH23A_HUMAN
|
||||||
NC score | 0.999962 (rank : 1) | θ value | 0 (rank : 1) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 149 | Shared Neighborhood Hits | 149 | |
SwissProt Accessions | Q9BRG2, Q9Y2X4 | Gene names | SH2D3A, NSP1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 3A (Novel SH2-containing protein 1). |
BCAR3_HUMAN
|
||||||
NC score | 0.921920 (rank : 2) | θ value | 2.81514e-94 (rank : 2) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 129 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | O75815, Q6UW40, Q9BR50 | Gene names | BCAR3, NSP2, SH2D3B | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2). |
BCAR3_MOUSE
|
||||||
NC score | 0.918700 (rank : 3) | θ value | 3.0147e-88 (rank : 3) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 127 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | Q9QZK2, Q3TNC9, Q3UP10 | Gene names | Bcar3, And34 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34). |
SH2D3_HUMAN
|
||||||
NC score | 0.892190 (rank : 4) | θ value | 2.03155e-68 (rank : 4) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 188 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5 | Gene names | SH2D3C, NSP3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 3C (Novel SH2-containing protein 3). |
SH2D3_MOUSE
|
||||||
NC score | 0.890637 (rank : 5) | θ value | 3.83135e-67 (rank : 5) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 174 | Shared Neighborhood Hits | 84 | |
SwissProt Accessions | Q9QZS8, Q9JME1 | Gene names | Sh2d3c, Chat, Shep1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer). |
SHC1_HUMAN
|
||||||
NC score | 0.552806 (rank : 6) | θ value | 4.30538e-10 (rank : 7) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 170 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P29353, O15290, Q8N4K5, Q96CL1 | Gene names | SHC1, SHC, SHCA | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1). |
SHC1_MOUSE
|
||||||
NC score | 0.551508 (rank : 7) | θ value | 4.30538e-10 (rank : 8) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 180 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7 | Gene names | Shc1, Shc, ShcA | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1). |
SHC2_MOUSE
|
||||||
NC score | 0.535343 (rank : 8) | θ value | 5.81887e-07 (rank : 14) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 144 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q8BMC3 | Gene names | Shc2, Sck, ShcB | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli). |
SHC2_HUMAN
|
||||||
NC score | 0.533354 (rank : 9) | θ value | 3.41135e-07 (rank : 13) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 170 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P98077, O60230, Q9NPL5, Q9UCX4 | Gene names | SHC2, SCK, SHCB | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck). |
SHC3_MOUSE
|
||||||
NC score | 0.530354 (rank : 10) | θ value | 1.80886e-08 (rank : 11) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | Q61120 | Gene names | Shc3, Nshc, ShcC | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc). |
SHC3_HUMAN
|
||||||
NC score | 0.523036 (rank : 11) | θ value | 2.61198e-07 (rank : 12) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 155 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q92529, Q8TAP2, Q9UCX5 | Gene names | SHC3, NSHC, SHCC | |||
Domain Architecture |
|
|||||
Description | SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai). |
SHD_MOUSE
|
||||||
NC score | 0.448391 (rank : 12) | θ value | 1.29631e-06 (rank : 15) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | O88834, Q3SYI7 | Gene names | Shd | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein D. |
APS_HUMAN
|
||||||
NC score | 0.446332 (rank : 13) | θ value | 0.00175202 (rank : 32) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 162 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | O14492 | Gene names | APS | |||
Domain Architecture |
|
|||||
Description | SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains). |
LNK_HUMAN
|
||||||
NC score | 0.445515 (rank : 14) | θ value | 9.29e-05 (rank : 26) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q9UQQ2, O95184 | Gene names | LNK | |||
Domain Architecture |
|
|||||
Description | Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein). |
SHB_MOUSE
|
||||||
NC score | 0.437583 (rank : 15) | θ value | 0.00869519 (rank : 46) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q6PD21, Q3ULM3 | Gene names | Shb | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein B. |
LNK_MOUSE
|
||||||
NC score | 0.436818 (rank : 16) | θ value | 0.00175202 (rank : 35) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 132 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | O09039 | Gene names | Lnk | |||
Domain Architecture |
|
|||||
Description | Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein). |
SHB_HUMAN
|
||||||
NC score | 0.434031 (rank : 17) | θ value | 0.00665767 (rank : 44) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 141 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q15464, Q504U5, Q5VUM8 | Gene names | SHB | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein B. |
SHD_HUMAN
|
||||||
NC score | 0.425282 (rank : 18) | θ value | 4.1701e-05 (rank : 23) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 204 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q96IW2, Q96NC2 | Gene names | SHD | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein D. |
SHE_HUMAN
|
||||||
NC score | 0.410392 (rank : 19) | θ value | 0.000270298 (rank : 28) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 164 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q5VZ18, Q8TEQ5 | Gene names | SHE | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein E. |
SHE_MOUSE
|
||||||
NC score | 0.407843 (rank : 20) | θ value | 0.00020696 (rank : 27) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 169 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q8BSD5, Q3TZT0 | Gene names | She | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing adapter protein E. |
CRK_HUMAN
|
||||||
NC score | 0.407449 (rank : 21) | θ value | 8.40245e-06 (rank : 16) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 308 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P46108 | Gene names | CRK | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene C-crk (P38) (Adapter molecule crk). |
APS_MOUSE
|
||||||
NC score | 0.407163 (rank : 22) | θ value | 0.00175202 (rank : 33) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 134 | Shared Neighborhood Hits | 77 | |
SwissProt Accessions | Q9JID9, O88936 | Gene names | Aps | |||
Domain Architecture |
|
|||||
Description | SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains). |
CRK_MOUSE
|
||||||
NC score | 0.399880 (rank : 23) | θ value | 8.40245e-06 (rank : 17) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 314 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | Q64010 | Gene names | Crk, Crko | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene C-crk (P38) (Adapter molecule crk). |
CRKL_HUMAN
|
||||||
NC score | 0.395543 (rank : 24) | θ value | 0.000786445 (rank : 30) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 313 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P46109 | Gene names | CRKL | |||
Domain Architecture |
|
|||||
Description | Crk-like protein. |
CRKL_MOUSE
|
||||||
NC score | 0.394765 (rank : 25) | θ value | 0.00175202 (rank : 34) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P47941, Q3TQ18, Q8BGC5 | Gene names | Crkl, Crkol | |||
Domain Architecture |
|
|||||
Description | Crk-like protein. |
DAPP1_HUMAN
|
||||||
NC score | 0.374479 (rank : 26) | θ value | 0.00390308 (rank : 40) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q9UN19, Q8TCK5, Q9UHF2 | Gene names | DAPP1, BAM32 | |||
Domain Architecture |
|
|||||
Description | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32). |
GRAP_HUMAN
|
||||||
NC score | 0.374047 (rank : 27) | θ value | 3.19293e-05 (rank : 22) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q13588 | Gene names | GRAP | |||
Domain Architecture |
|
|||||
Description | GRB2-related adapter protein. |
GRAP_MOUSE
|
||||||
NC score | 0.370139 (rank : 28) | θ value | 9.29e-05 (rank : 25) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 309 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q9CX99, Q3U545 | Gene names | Grap | |||
Domain Architecture |
No domain graphic available |
|||||
Description | GRB2-related adapter protein. |
DAPP1_MOUSE
|
||||||
NC score | 0.364847 (rank : 29) | θ value | 0.00298849 (rank : 38) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q9QXT1, Q9R178 | Gene names | Dapp1, Bam32 | |||
Domain Architecture |
|
|||||
Description | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32). |
GRB2_MOUSE
|
||||||
NC score | 0.358279 (rank : 30) | θ value | 0.00228821 (rank : 37) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 312 | Shared Neighborhood Hits | 94 | |
SwissProt Accessions | Q60631, Q61240 | Gene names | Grb2 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2). |
GRB2_HUMAN
|
||||||
NC score | 0.358145 (rank : 31) | θ value | 0.00228821 (rank : 36) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P62993, P29354, Q14450, Q63057, Q63059 | Gene names | GRB2, ASH | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash). |
NCK1_HUMAN
|
||||||
NC score | 0.352878 (rank : 32) | θ value | 0.000602161 (rank : 29) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 312 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P16333 | Gene names | NCK1, NCK | |||
Domain Architecture |
|
|||||
Description | Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha). |
HSH2D_HUMAN
|
||||||
NC score | 0.339739 (rank : 33) | θ value | 0.00665767 (rank : 43) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 159 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | Q96JZ2, Q6ZNG7 | Gene names | HSH2D, ALX | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X). |
GRAP2_MOUSE
|
||||||
NC score | 0.338384 (rank : 34) | θ value | 5.44631e-05 (rank : 24) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 297 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O89100 | Gene names | Grap2, Gads, Grb2l, Grid, Mona | |||
Domain Architecture |
|
|||||
Description | GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID). |
NCK2_HUMAN
|
||||||
NC score | 0.338362 (rank : 35) | θ value | 0.00298849 (rank : 39) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | O43639, Q9BWN9, Q9UIC3 | Gene names | NCK2 | |||
Domain Architecture |
|
|||||
Description | Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2). |
GRAP2_HUMAN
|
||||||
NC score | 0.336267 (rank : 36) | θ value | 2.44474e-05 (rank : 21) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 304 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O75791, O43726 | Gene names | GRAP2, GADS, GRB2L, GRID | |||
Domain Architecture |
|
|||||
Description | GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona). |
SH21B_HUMAN
|
||||||
NC score | 0.323565 (rank : 37) | θ value | 0.813845 (rank : 83) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 101 | Shared Neighborhood Hits | 70 | |
SwissProt Accessions | O14796, Q5T0L1, Q8NI18, Q969K9 | Gene names | SH2D1B, EAT2 | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2). |
RASA1_HUMAN
|
||||||
NC score | 0.303440 (rank : 38) | θ value | 0.47712 (rank : 76) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 258 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | P20936 | Gene names | RASA1, RASA | |||
Domain Architecture |
|
|||||
Description | Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP). |
HSH2D_MOUSE
|
||||||
NC score | 0.296757 (rank : 39) | θ value | 0.813845 (rank : 80) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 124 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q6VYH9, Q52KL3 | Gene names | Hsh2d, Alx | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X). |
SH21B_MOUSE
|
||||||
NC score | 0.291992 (rank : 40) | θ value | 0.279714 (rank : 70) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 101 | Shared Neighborhood Hits | 69 | |
SwissProt Accessions | O35324, Q8C268 | Gene names | Sh2d1b, Eat2, Sh2d1b1 | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2). |
GRB7_MOUSE
|
||||||
NC score | 0.280921 (rank : 41) | θ value | 0.813845 (rank : 79) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 157 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q03160 | Gene names | Grb7 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7). |
GRB14_MOUSE
|
||||||
NC score | 0.279798 (rank : 42) | θ value | 1.06291 (rank : 85) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 149 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | Q9JLM9, Q3UI77, Q8VDI2, Q9CR03 | Gene names | Grb14 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 14 (GRB14 adapter protein). |
GRB14_HUMAN
|
||||||
NC score | 0.274836 (rank : 43) | θ value | 0.21417 (rank : 66) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 137 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q14449, Q7Z6I1 | Gene names | GRB14 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 14 (GRB14 adapter protein). |
SH22A_MOUSE
|
||||||
NC score | 0.268332 (rank : 44) | θ value | 2.36792 (rank : 105) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 179 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q9QXK9, Q9JHP6 | Gene names | Sh2d2a, Lad, Ribp | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp). |
SH22A_HUMAN
|
||||||
NC score | 0.264426 (rank : 45) | θ value | 0.0961366 (rank : 63) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 144 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q9NP31, O43817, Q9UPA7 | Gene names | SH2D2A, SCAP, TSAD, VRAP | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein). |
GRB7_HUMAN
|
||||||
NC score | 0.264415 (rank : 46) | θ value | 6.88961 (rank : 135) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 156 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | Q14451, Q92568, Q96DF9 | Gene names | GRB7 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47). |
SH21A_MOUSE
|
||||||
NC score | 0.251370 (rank : 47) | θ value | θ > 10 (rank : 340) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 89 | Shared Neighborhood Hits | 61 | |
SwissProt Accessions | O88890, Q9QWV6 | Gene names | Sh2d1a, Xlp | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP). |
SH21A_HUMAN
|
||||||
NC score | 0.250337 (rank : 48) | θ value | θ > 10 (rank : 339) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 89 | Shared Neighborhood Hits | 60 | |
SwissProt Accessions | O60880, O95383, O95384, O95385, O95386, Q9UNR0 | Gene names | SH2D1A, DSHP, SAP | |||
Domain Architecture |
|
|||||
Description | SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein). |
PLCG2_HUMAN
|
||||||
NC score | 0.240216 (rank : 49) | θ value | 5.27518 (rank : 129) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 280 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P16885, Q969T5 | Gene names | PLCG2 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV). |
GRB10_MOUSE
|
||||||
NC score | 0.238673 (rank : 50) | θ value | θ > 10 (rank : 246) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 156 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5 | Gene names | Grb10 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 10 (GRB10 adaptor protein). |
GRB10_HUMAN
|
||||||
NC score | 0.237392 (rank : 51) | θ value | θ > 10 (rank : 245) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 147 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948 | Gene names | GRB10, GRBIR, KIAA0207 | |||
Domain Architecture |
|
|||||
Description | Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR). |
PLCG1_HUMAN
|
||||||
NC score | 0.236532 (rank : 52) | θ value | θ > 10 (rank : 322) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 293 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P19174, Q2V575 | Gene names | PLCG1, PLC1 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148). |
PLCG1_MOUSE
|
||||||
NC score | 0.234748 (rank : 53) | θ value | θ > 10 (rank : 323) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 314 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | Q62077, Q6P1G1 | Gene names | Plcg1, Plcg-1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148). |
VAV3_HUMAN
|
||||||
NC score | 0.223120 (rank : 54) | θ value | 0.0431538 (rank : 55) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 398 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q9UKW4, O95230, Q9Y5X8 | Gene names | VAV3 | |||
Domain Architecture |
|
|||||
Description | Protein vav-3. |
VAV3_MOUSE
|
||||||
NC score | 0.222001 (rank : 55) | θ value | 0.0736092 (rank : 61) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 404 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | Q9R0C8, Q7TS85 | Gene names | Vav3 | |||
Domain Architecture |
|
|||||
Description | Protein vav-3. |
PTN11_MOUSE
|
||||||
NC score | 0.217887 (rank : 56) | θ value | 0.0148317 (rank : 49) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P35235, Q3TQ84, Q64509, Q6PCL5 | Gene names | Ptpn11 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2). |
PTN11_HUMAN
|
||||||
NC score | 0.217862 (rank : 57) | θ value | 0.0148317 (rank : 48) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | Q06124, Q96HD7 | Gene names | PTPN11, PTP2C, SHPTP2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2). |
SH24A_MOUSE
|
||||||
NC score | 0.216365 (rank : 58) | θ value | 1.81305 (rank : 102) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 326 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q9D7V1 | Gene names | Sh2d4a | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 4A. |
VAV_HUMAN
|
||||||
NC score | 0.211781 (rank : 59) | θ value | 6.88961 (rank : 140) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 452 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P15498, Q15860 | Gene names | VAV1, VAV | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene vav. |
PTN6_MOUSE
|
||||||
NC score | 0.202226 (rank : 60) | θ value | 0.00869519 (rank : 45) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6 | Gene names | Ptpn6, Hcp, Hcph, Ptp1C | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42). |
VAV2_HUMAN
|
||||||
NC score | 0.201430 (rank : 61) | θ value | 0.365318 (rank : 75) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 453 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | P52735 | Gene names | VAV2 | |||
Domain Architecture |
|
|||||
Description | Protein vav-2. |
SLAP2_HUMAN
|
||||||
NC score | 0.197762 (rank : 62) | θ value | 8.99809 (rank : 149) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 139 | Shared Neighborhood Hits | 75 | |
SwissProt Accessions | Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135 | Gene names | SLA2, C20orf156, SLAP2 | |||
Domain Architecture |
|
|||||
Description | Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS). |
SH24A_HUMAN
|
||||||
NC score | 0.197223 (rank : 63) | θ value | 3.0926 (rank : 112) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 455 | Shared Neighborhood Hits | 64 | |
SwissProt Accessions | Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7 | Gene names | SH2D4A, SH2A | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH2 domain-containing protein 4A (Protein SH(2)A). |
VAV2_MOUSE
|
||||||
NC score | 0.196483 (rank : 64) | θ value | 1.06291 (rank : 90) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 456 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q60992 | Gene names | Vav2 | |||
Domain Architecture |
|
|||||
Description | Protein vav-2. |
PTN6_HUMAN
|
||||||
NC score | 0.196063 (rank : 65) | θ value | 0.0148317 (rank : 50) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 234 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P29350, Q969V8 | Gene names | PTPN6, HCP, PTP1C | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1). |
VAV_MOUSE
|
||||||
NC score | 0.191291 (rank : 66) | θ value | θ > 10 (rank : 397) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 430 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P27870, Q8BTV7 | Gene names | Vav1, Vav | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene vav (p95vav). |
SLAP2_MOUSE
|
||||||
NC score | 0.183355 (rank : 67) | θ value | θ > 10 (rank : 350) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 136 | Shared Neighborhood Hits | 71 | |
SwissProt Accessions | Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9 | Gene names | Sla2 | |||
Domain Architecture |
|
|||||
Description | Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2). |
FER_HUMAN
|
||||||
NC score | 0.177321 (rank : 68) | θ value | 3.64472e-09 (rank : 10) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1278 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | P16591 | Gene names | FER, TYK3 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER). |
P85B_HUMAN
|
||||||
NC score | 0.173886 (rank : 69) | θ value | 4.03905 (rank : 118) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 543 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | O00459, Q9UPH9 | Gene names | PIK3R2 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta). |
SOCS6_MOUSE
|
||||||
NC score | 0.173828 (rank : 70) | θ value | 2.36792 (rank : 107) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 146 | Shared Neighborhood Hits | 65 | |
SwissProt Accessions | Q9JLY0, Q9D2A0 | Gene names | Socs6, Cis4, Cish4, Socs4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4). |
SLAP1_HUMAN
|
||||||
NC score | 0.172108 (rank : 71) | θ value | θ > 10 (rank : 348) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 113 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | Q13239, Q9UMQ8 | Gene names | SLA, SLAP, SLAP1 | |||
Domain Architecture |
|
|||||
Description | SRC-like-adapter (Src-like-adapter protein 1) (hSLAP). |
SLAP1_MOUSE
|
||||||
NC score | 0.170353 (rank : 72) | θ value | θ > 10 (rank : 349) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 117 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8 | Gene names | Sla, Slap, Slap1 | |||
Domain Architecture |
|
|||||
Description | SRC-like-adapter (Src-like-adapter protein 1) (mSLAP). |
P85B_MOUSE
|
||||||
NC score | 0.168702 (rank : 73) | θ value | θ > 10 (rank : 309) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 519 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | O08908 | Gene names | Pik3r2 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta). |
ABL2_HUMAN
|
||||||
NC score | 0.167606 (rank : 74) | θ value | 1.87187e-05 (rank : 20) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1045 | Shared Neighborhood Hits | 95 | |
SwissProt Accessions | P42684, Q5T0X6, Q6NZY6 | Gene names | ABL2, ABLL, ARG | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG). |
SOCS6_HUMAN
|
||||||
NC score | 0.166965 (rank : 75) | θ value | 2.36792 (rank : 106) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 63 | |
SwissProt Accessions | O14544 | Gene names | SOCS6, CIS4, SOCS4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4). |
ABL1_HUMAN
|
||||||
NC score | 0.164833 (rank : 76) | θ value | 1.43324e-05 (rank : 18) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1220 | Shared Neighborhood Hits | 98 | |
SwissProt Accessions | P00519, Q13869, Q13870, Q16133, Q45F09 | Gene names | ABL1, ABL, JTK7 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). |
ABL1_MOUSE
|
||||||
NC score | 0.164333 (rank : 77) | θ value | 1.43324e-05 (rank : 19) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1178 | Shared Neighborhood Hits | 97 | |
SwissProt Accessions | P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4 | Gene names | Abl1, Abl | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). |
P85A_MOUSE
|
||||||
NC score | 0.161354 (rank : 78) | θ value | θ > 10 (rank : 308) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 435 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P26450 | Gene names | Pik3r1 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K). |
P85A_HUMAN
|
||||||
NC score | 0.157318 (rank : 79) | θ value | θ > 10 (rank : 307) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 479 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | P27986 | Gene names | PIK3R1, GRB1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K). |
P55G_HUMAN
|
||||||
NC score | 0.150856 (rank : 80) | θ value | θ > 10 (rank : 305) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 451 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | Q92569, O60482 | Gene names | PIK3R3 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK). |
CSK_MOUSE
|
||||||
NC score | 0.149372 (rank : 81) | θ value | 0.00665767 (rank : 42) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41241, Q03143 | Gene names | Csk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK). |
FES_HUMAN
|
||||||
NC score | 0.149069 (rank : 82) | θ value | 1.9326e-10 (rank : 6) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 978 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P07332 | Gene names | FES, FPS | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes). |
CSK_HUMAN
|
||||||
NC score | 0.147739 (rank : 83) | θ value | 0.0193708 (rank : 52) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41240, Q6FGZ6 | Gene names | CSK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL). |
P55G_MOUSE
|
||||||
NC score | 0.146933 (rank : 84) | θ value | θ > 10 (rank : 306) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 401 | Shared Neighborhood Hits | 76 | |
SwissProt Accessions | Q64143 | Gene names | Pik3r3 | |||
Domain Architecture |
|
|||||
Description | Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK). |
CHIN_MOUSE
|
||||||
NC score | 0.144007 (rank : 85) | θ value | 1.81305 (rank : 98) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 229 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3 | Gene names | Chn1, Arhgap2 | |||
Domain Architecture |
|
|||||
Description | N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2). |
FES_MOUSE
|
||||||
NC score | 0.142137 (rank : 86) | θ value | 1.63604e-09 (rank : 9) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 64 | |
SwissProt Accessions | P16879, Q62122 | Gene names | Fes, Fps | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes). |
SOCS2_MOUSE
|
||||||
NC score | 0.138990 (rank : 87) | θ value | θ > 10 (rank : 354) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | O35717 | Gene names | Socs2, Cis2, Cish2 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2). |
SOCS2_HUMAN
|
||||||
NC score | 0.138511 (rank : 88) | θ value | θ > 10 (rank : 353) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 104 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | O14508, O14542, O95102, Q9UKS5 | Gene names | SOCS2, CIS2, SSI2, STATI2 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2). |
FGR_MOUSE
|
||||||
NC score | 0.138135 (rank : 89) | θ value | 2.36792 (rank : 103) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1069 | Shared Neighborhood Hits | 98 | |
SwissProt Accessions | P14234, Q61404 | Gene names | Fgr | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR). |
MATK_HUMAN
|
||||||
NC score | 0.136605 (rank : 90) | θ value | 0.0563607 (rank : 58) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 954 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P42679 | Gene names | MATK, CTK, HYL | |||
Domain Architecture |
|
|||||
Description | Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase). |
MATK_MOUSE
|
||||||
NC score | 0.135683 (rank : 91) | θ value | 0.0736092 (rank : 60) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 952 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P41242, Q6LE90 | Gene names | Matk, Ctk, Ntk | |||
Domain Architecture |
|
|||||
Description | Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK). |
CHIN_HUMAN
|
||||||
NC score | 0.134643 (rank : 92) | θ value | 5.27518 (rank : 125) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P15882, Q53SD6, Q53SH5, Q96FB0 | Gene names | CHN1, ARHGAP2, CHN | |||
Domain Architecture |
|
|||||
Description | N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2). |
LCP2_MOUSE
|
||||||
NC score | 0.132056 (rank : 93) | θ value | 3.0926 (rank : 109) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 177 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q60787 | Gene names | Lcp2 | |||
Domain Architecture |
|
|||||
Description | Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76). |
PTK6_HUMAN
|
||||||
NC score | 0.129960 (rank : 94) | θ value | 0.0148317 (rank : 47) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1020 | Shared Neighborhood Hits | 87 | |
SwissProt Accessions | Q13882 | Gene names | PTK6, BRK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK). |
FGR_HUMAN
|
||||||
NC score | 0.129075 (rank : 95) | θ value | θ > 10 (rank : 239) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1067 | Shared Neighborhood Hits | 96 | |
SwissProt Accessions | P09769, Q9UIQ3 | Gene names | FGR, SRC2 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR). |
FRK_HUMAN
|
||||||
NC score | 0.127958 (rank : 96) | θ value | θ > 10 (rank : 242) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1058 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P42685, Q13128 | Gene names | FRK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK). |
PTK6_MOUSE
|
||||||
NC score | 0.127872 (rank : 97) | θ value | 0.0563607 (rank : 59) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q64434 | Gene names | Ptk6, Sik | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase). |
KSYK_HUMAN
|
||||||
NC score | 0.127412 (rank : 98) | θ value | 0.0563607 (rank : 57) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 901 | Shared Neighborhood Hits | 89 | |
SwissProt Accessions | P43405 | Gene names | SYK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase). |
SRC_MOUSE
|
||||||
NC score | 0.127216 (rank : 99) | θ value | θ > 10 (rank : 365) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1033 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P05480 | Gene names | Src | |||
Domain Architecture |
|
|||||
Description | Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src). |
SRC_HUMAN
|
||||||
NC score | 0.127177 (rank : 100) | θ value | θ > 10 (rank : 364) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1058 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P12931, Q86VB9, Q9H5A8 | Gene names | SRC, SRC1 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). |
SRMS_MOUSE
|
||||||
NC score | 0.127052 (rank : 101) | θ value | 0.00102713 (rank : 31) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 964 | Shared Neighborhood Hits | 88 | |
SwissProt Accessions | Q62270, Q62360, Q923M5 | Gene names | Srms, Srm | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70). |
YES_HUMAN
|
||||||
NC score | 0.126919 (rank : 102) | θ value | 4.03905 (rank : 122) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1059 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | P07947 | Gene names | YES1, YES | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes). |
YES_MOUSE
|
||||||
NC score | 0.126701 (rank : 103) | θ value | 3.0926 (rank : 115) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1052 | Shared Neighborhood Hits | 92 | |
SwissProt Accessions | Q04736 | Gene names | Yes1, Yes | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes). |
SRMS_HUMAN
|
||||||
NC score | 0.125074 (rank : 104) | θ value | 0.0148317 (rank : 51) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 946 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | Q9H3Y6 | Gene names | SRMS, C20orf148 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Srms (EC 2.7.10.2). |
KSYK_MOUSE
|
||||||
NC score | 0.124748 (rank : 105) | θ value | 0.163984 (rank : 65) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 944 | Shared Neighborhood Hits | 91 | |
SwissProt Accessions | P48025 | Gene names | Syk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase). |
FYN_MOUSE
|
||||||
NC score | 0.120651 (rank : 106) | θ value | θ > 10 (rank : 244) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1073 | Shared Neighborhood Hits | 90 | |
SwissProt Accessions | P39688 | Gene names | Fyn | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn). |
FYN_HUMAN
|
||||||
NC score | 0.120247 (rank : 107) | θ value | θ > 10 (rank : 243) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1078 | Shared Neighborhood Hits | 93 | |
SwissProt Accessions | P06241 | Gene names | FYN | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK). |
LCP2_HUMAN
|
||||||
NC score | 0.120079 (rank : 108) | θ value | 3.0926 (rank : 108) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 531 | Shared Neighborhood Hits | 63 | |
SwissProt Accessions | Q13094 | Gene names | LCP2 | |||
Domain Architecture |
|
|||||
Description | Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76). |
SOCS7_MOUSE
|
||||||
NC score | 0.116880 (rank : 109) | θ value | θ > 10 (rank : 359) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 154 | Shared Neighborhood Hits | 58 | |
SwissProt Accessions | Q8VHQ2 | Gene names | Socs7, Cish7, Nap4 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 7 (SOCS-7). |
TXK_MOUSE
|
||||||
NC score | 0.114373 (rank : 110) | θ value | θ > 10 (rank : 390) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P42682 | Gene names | Txk, Rlk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase). |
LCK_HUMAN
|
||||||
NC score | 0.113991 (rank : 111) | θ value | 8.99809 (rank : 146) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 987 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8 | Gene names | LCK | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase). |
LCK_MOUSE
|
||||||
NC score | 0.113039 (rank : 112) | θ value | 8.99809 (rank : 147) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 981 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | P06240, Q61794, Q61795, Q62320, Q91X65 | Gene names | Lck, Lsk-t | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK). |
BMX_HUMAN
|
||||||
NC score | 0.111559 (rank : 113) | θ value | 0.0330416 (rank : 54) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 942 | Shared Neighborhood Hits | 79 | |
SwissProt Accessions | P51813, O60564, Q12871 | Gene names | BMX | |||
Domain Architecture |
|
|||||
Description | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38). |
HCK_HUMAN
|
||||||
NC score | 0.111228 (rank : 114) | θ value | θ > 10 (rank : 249) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1035 | Shared Neighborhood Hits | 85 | |
SwissProt Accessions | P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5 | Gene names | HCK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase). |
BLK_MOUSE
|
||||||
NC score | 0.110798 (rank : 115) | θ value | θ > 10 (rank : 171) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 992 | Shared Neighborhood Hits | 82 | |
SwissProt Accessions | P16277 | Gene names | Blk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK). |
HCK_MOUSE
|
||||||
NC score | 0.110274 (rank : 116) | θ value | θ > 10 (rank : 250) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1029 | Shared Neighborhood Hits | 80 | |
SwissProt Accessions | P08103 | Gene names | Hck | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK). |
BMX_MOUSE
|
||||||
NC score | 0.109777 (rank : 117) | θ value | 0.0563607 (rank : 56) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 912 | Shared Neighborhood Hits | 78 | |
SwissProt Accessions | P97504 | Gene names | Bmx | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog). |
TXK_HUMAN
|
||||||
NC score | 0.109062 (rank : 118) | θ value | θ > 10 (rank : 389) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 971 | Shared Neighborhood Hits | 77 | |
SwissProt Accessions | P42681, Q14220 | Gene names | TXK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase TXK (EC 2.7.10.2). |
BLNK_MOUSE
|
||||||
NC score | 0.108871 (rank : 119) | θ value | 1.81305 (rank : 97) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 296 | Shared Neighborhood Hits | 47 | |
SwissProt Accessions | Q9QUN3, O88504 | Gene names | Blnk, Bash, Ly57, Slp65 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57). |
BTK_HUMAN
|
||||||
NC score | 0.107285 (rank : 120) | θ value | θ > 10 (rank : 174) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 74 | |
SwissProt Accessions | Q06187 | Gene names | BTK, AGMX1, ATK, BPK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK). |
BTK_MOUSE
|
||||||
NC score | 0.106874 (rank : 121) | θ value | θ > 10 (rank : 175) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1017 | Shared Neighborhood Hits | 73 | |
SwissProt Accessions | P35991, Q61365 | Gene names | Btk, Bpk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB). |
LYN_MOUSE
|
||||||
NC score | 0.106684 (rank : 122) | θ value | θ > 10 (rank : 278) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1023 | Shared Neighborhood Hits | 84 | |
SwissProt Accessions | P25911, Q62127 | Gene names | Lyn | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Lyn (EC 2.7.10.2). |
ITK_HUMAN
|
||||||
NC score | 0.105799 (rank : 123) | θ value | θ > 10 (rank : 262) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1016 | Shared Neighborhood Hits | 81 | |
SwissProt Accessions | Q08881 | Gene names | ITK, EMT, LYK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT). |
LYN_HUMAN
|
||||||
NC score | 0.105505 (rank : 124) | θ value | θ > 10 (rank : 277) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1022 | Shared Neighborhood Hits | 83 | |
SwissProt Accessions | P07948 | Gene names | LYN | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Lyn (EC 2.7.10.2). |
BLK_HUMAN
|
||||||
NC score | 0.105466 (rank : 125) | θ value | θ > 10 (rank : 170) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 994 | Shared Neighborhood Hits | 74 | |
SwissProt Accessions | P51451, Q16291 | Gene names | BLK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK). |
ITK_MOUSE
|
||||||
NC score | 0.105031 (rank : 126) | θ value | θ > 10 (rank : 263) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 985 | Shared Neighborhood Hits | 78 | |
SwissProt Accessions | Q03526 | Gene names | Itk, Emt, Tlk, Tsk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK). |
CHIO_HUMAN
|
||||||
NC score | 0.103038 (rank : 127) | θ value | 8.99809 (rank : 145) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 220 | Shared Neighborhood Hits | 72 | |
SwissProt Accessions | P52757, Q75MM2 | Gene names | CHN2, ARHGAP3, BCH | |||
Domain Architecture |
|
|||||
Description | Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3). |
TEC_HUMAN
|
||||||
NC score | 0.101934 (rank : 128) | θ value | θ > 10 (rank : 376) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1006 | Shared Neighborhood Hits | 69 | |
SwissProt Accessions | P42680 | Gene names | TEC, PSCTK4 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Tec (EC 2.7.10.2). |
TEC_MOUSE
|
||||||
NC score | 0.099293 (rank : 129) | θ value | θ > 10 (rank : 377) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1006 | Shared Neighborhood Hits | 65 | |
SwissProt Accessions | P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3 | Gene names | Tec | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase Tec (EC 2.7.10.2). |
ZAP70_MOUSE
|
||||||
NC score | 0.098897 (rank : 130) | θ value | 4.03905 (rank : 124) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 905 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | P43404 | Gene names | Zap70, Srk, Zap-70 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase). |
ZAP70_HUMAN
|
||||||
NC score | 0.097833 (rank : 131) | θ value | 4.03905 (rank : 123) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 893 | Shared Neighborhood Hits | 86 | |
SwissProt Accessions | P43403 | Gene names | ZAP70, SRK | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase). |
CISH_HUMAN
|
||||||
NC score | 0.096727 (rank : 132) | θ value | θ > 10 (rank : 179) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 48 | |
SwissProt Accessions | Q9NSE2, Q9NS38, Q9Y5R1 | Gene names | CISH, G18 | |||
Domain Architecture |
|
|||||
Description | Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18). |
CISH_MOUSE
|
||||||
NC score | 0.095425 (rank : 133) | θ value | θ > 10 (rank : 180) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 94 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q62225, Q3TC70 | Gene names | Cish, Cis | |||
Domain Architecture |
|
|||||
Description | Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS). |
BLNK_HUMAN
|
||||||
NC score | 0.093922 (rank : 134) | θ value | θ > 10 (rank : 172) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 228 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q8WV28, O75498, O75499 | Gene names | BLNK, BASH, SLP65 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65). |
SELV_HUMAN
|
||||||
NC score | 0.092259 (rank : 135) | θ value | 0.00509761 (rank : 41) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 118 | Shared Neighborhood Hits | 7 | |
SwissProt Accessions | P59797 | Gene names | SELV | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Selenoprotein V. |
SOCS5_HUMAN
|
||||||
NC score | 0.087326 (rank : 136) | θ value | 3.0926 (rank : 113) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 91 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | O75159, Q8IYZ4 | Gene names | SOCS5, CIS6, CISH5, CISH6, KIAA0671 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6). |
SOCS5_MOUSE
|
||||||
NC score | 0.087224 (rank : 137) | θ value | 3.0926 (rank : 114) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 93 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | O54928 | Gene names | Socs5, Cish5 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5). |
NPHP1_MOUSE
|
||||||
NC score | 0.086477 (rank : 138) | θ value | θ > 10 (rank : 298) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 267 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2 | Gene names | Nphp1, Nph1 | |||
Domain Architecture |
|
|||||
Description | Nephrocystin-1. |
NPHP1_HUMAN
|
||||||
NC score | 0.083244 (rank : 139) | θ value | θ > 10 (rank : 297) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 288 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O15259, O14837 | Gene names | NPHP1, NPH1 | |||
Domain Architecture |
|
|||||
Description | Nephrocystin-1 (Juvenile nephronophthisis 1 protein). |
SRBS1_MOUSE
|
||||||
NC score | 0.076661 (rank : 140) | θ value | θ > 10 (rank : 361) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 409 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9 | Gene names | Sorbs1, Kiaa1296, Sh3d5 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12). |
CD2AP_HUMAN
|
||||||
NC score | 0.075638 (rank : 141) | θ value | θ > 10 (rank : 176) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 315 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9Y5K6, Q9UG97 | Gene names | CD2AP | |||
Domain Architecture |
|
|||||
Description | CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS). |
STAM1_MOUSE
|
||||||
NC score | 0.074465 (rank : 142) | θ value | θ > 10 (rank : 371) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 273 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | P70297 | Gene names | Stam, Stam1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 1 (STAM-1). |
STAM1_HUMAN
|
||||||
NC score | 0.074397 (rank : 143) | θ value | θ > 10 (rank : 370) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 271 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q92783, Q8N6D9 | Gene names | STAM, STAM1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 1 (STAM-1). |
SRBS1_HUMAN
|
||||||
NC score | 0.073765 (rank : 144) | θ value | θ > 10 (rank : 360) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 396 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338 | Gene names | SORBS1, KIAA1296, SH3D5 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12). |
RYK_HUMAN
|
||||||
NC score | 0.072209 (rank : 145) | θ value | θ > 10 (rank : 337) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 701 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P34925, Q04696 | Gene names | RYK, JTK5A | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase RYK precursor (EC 2.7.10.1). |
CD2AP_MOUSE
|
||||||
NC score | 0.072009 (rank : 146) | θ value | θ > 10 (rank : 177) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 336 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q9JLQ0, O88903, Q8K4Z1, Q8VCI9 | Gene names | Cd2ap, Mets1 | |||
Domain Architecture |
|
|||||
Description | CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1). |
RYK_MOUSE
|
||||||
NC score | 0.071648 (rank : 147) | θ value | θ > 10 (rank : 338) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 715 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q01887, Q61890 | Gene names | Ryk, Mrk | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase). |
STYK1_HUMAN
|
||||||
NC score | 0.071599 (rank : 148) | θ value | θ > 10 (rank : 374) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 786 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q6J9G0, Q9BXY2, Q9NSH1 | Gene names | STYK1, NOK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique). |
STAC_MOUSE
|
||||||
NC score | 0.071397 (rank : 149) | θ value | θ > 10 (rank : 369) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 268 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | P97306 | Gene names | Stac | |||
Domain Architecture |
|
|||||
Description | SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein). |
SOCS3_HUMAN
|
||||||
NC score | 0.071110 (rank : 150) | θ value | θ > 10 (rank : 355) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 77 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O14543, O14509 | Gene names | SOCS3, CIS3, SSI3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3). |
STYK1_MOUSE
|
||||||
NC score | 0.071061 (rank : 151) | θ value | θ > 10 (rank : 375) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 779 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q6J9G1, Q8BZH6, Q8BZT1 | Gene names | Styk1, Nok | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK). |
LTK_HUMAN
|
||||||
NC score | 0.070957 (rank : 152) | θ value | θ > 10 (rank : 275) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 774 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P29376 | Gene names | LTK, TYK1 | |||
Domain Architecture |
|
|||||
Description | Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1). |
LTK_MOUSE
|
||||||
NC score | 0.070105 (rank : 153) | θ value | θ > 10 (rank : 276) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 770 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P08923 | Gene names | Ltk | |||
Domain Architecture |
|
|||||
Description | Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1). |
RAD21_HUMAN
|
||||||
NC score | 0.070000 (rank : 154) | θ value | 0.0961366 (rank : 62) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 46 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | O60216, Q15001, Q99568 | Gene names | RAD21, HR21, KIAA0078, NXP1 | |||
Domain Architecture |
|
|||||
Description | Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog). |
VINEX_MOUSE
|
||||||
NC score | 0.069936 (rank : 155) | θ value | θ > 10 (rank : 405) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 286 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9R1Z8, Q62423 | Gene names | Sorbs3, Scam1, Sh3d4 | |||
Domain Architecture |
|
|||||
Description | Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3). |
ALK_MOUSE
|
||||||
NC score | 0.069851 (rank : 156) | θ value | θ > 10 (rank : 160) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 811 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P97793 | Gene names | Alk | |||
Domain Architecture |
|
|||||
Description | ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen). |
ALK_HUMAN
|
||||||
NC score | 0.069433 (rank : 157) | θ value | θ > 10 (rank : 159) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 795 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q9UM73, Q9Y4K6 | Gene names | ALK | |||
Domain Architecture |
|
|||||
Description | ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen). |
SOCS3_MOUSE
|
||||||
NC score | 0.069315 (rank : 158) | θ value | θ > 10 (rank : 356) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 72 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | O35718, P97803, Q3U7X5 | Gene names | Socs3, Cis3, Cish3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10). |
STAM2_HUMAN
|
||||||
NC score | 0.068927 (rank : 159) | θ value | θ > 10 (rank : 372) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 288 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | O75886, Q7LDQ0, Q9UF58 | Gene names | STAM2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 2 (STAM-2). |
ACK1_MOUSE
|
||||||
NC score | 0.068925 (rank : 160) | θ value | θ > 10 (rank : 157) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1080 | Shared Neighborhood Hits | 47 | |
SwissProt Accessions | O54967, Q8C2U0, Q8K0K4 | Gene names | Tnk2, Ack1 | |||
Domain Architecture |
|
|||||
Description | Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2). |
STAC_HUMAN
|
||||||
NC score | 0.068735 (rank : 161) | θ value | θ > 10 (rank : 368) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 276 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q99469 | Gene names | STAC | |||
Domain Architecture |
|
|||||
Description | SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein). |
ACK1_HUMAN
|
||||||
NC score | 0.068536 (rank : 162) | θ value | θ > 10 (rank : 156) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1140 | Shared Neighborhood Hits | 46 | |
SwissProt Accessions | Q07912, Q8N6U7, Q96H59 | Gene names | TNK2, ACK1 | |||
Domain Architecture |
|
|||||
Description | Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2). |
DNMBP_HUMAN
|
||||||
NC score | 0.068248 (rank : 163) | θ value | θ > 10 (rank : 188) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 413 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q6XZF7, Q8IVY3, Q9Y2L3 | Gene names | DNMBP, KIAA1010 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Dynamin-binding protein (Scaffold protein Tuba). |
NCF2_HUMAN
|
||||||
NC score | 0.067852 (rank : 164) | θ value | θ > 10 (rank : 295) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 229 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P19878, Q2PP06, Q8NFC7, Q9BV51 | Gene names | NCF2 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2). |
PPIP1_HUMAN
|
||||||
NC score | 0.067843 (rank : 165) | θ value | θ > 10 (rank : 324) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 389 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | O43586, O43585, O95657 | Gene names | PSTPIP1, CD2BP1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP). |
SH3K1_HUMAN
|
||||||
NC score | 0.067431 (rank : 166) | θ value | θ > 10 (rank : 346) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 341 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0 | Gene names | SH3KBP1, CIN85 | |||
Domain Architecture |
|
|||||
Description | SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3). |
RPGF3_MOUSE
|
||||||
NC score | 0.067411 (rank : 167) | θ value | 1.38821 (rank : 94) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 54 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q8VCC8, Q8BZK9, Q8R1R1 | Gene names | Rapgef3, Epac, Epac1 | |||
Domain Architecture |
|
|||||
Description | Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1). |
ROS_HUMAN
|
||||||
NC score | 0.067372 (rank : 168) | θ value | θ > 10 (rank : 336) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 907 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P08922, Q15368 | Gene names | ROS1 | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1). |
VINEX_HUMAN
|
||||||
NC score | 0.067276 (rank : 169) | θ value | θ > 10 (rank : 404) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 270 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | O60504, Q9UQE4 | Gene names | SORBS3, SCAM1 | |||
Domain Architecture |
|
|||||
Description | Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1). |
MERTK_HUMAN
|
||||||
NC score | 0.067244 (rank : 170) | θ value | θ > 10 (rank : 283) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q12866, Q9HBB4 | Gene names | MERTK, MER | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). |
STAC3_HUMAN
|
||||||
NC score | 0.067205 (rank : 171) | θ value | θ > 10 (rank : 366) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 228 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q96MF2, Q96HU5 | Gene names | STAC3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH3 and cysteine-rich domain-containing protein 3. |
STAC3_MOUSE
|
||||||
NC score | 0.067145 (rank : 172) | θ value | θ > 10 (rank : 367) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 232 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8BZ71 | Gene names | Stac3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | SH3 and cysteine-rich domain-containing protein 3. |
TENS4_MOUSE
|
||||||
NC score | 0.066869 (rank : 173) | θ value | θ > 10 (rank : 380) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 225 | Shared Neighborhood Hits | 54 | |
SwissProt Accessions | Q8BZ33, Q3TCM8, Q7TNR5 | Gene names | Tns4 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-4 precursor. |
AATK_MOUSE
|
||||||
NC score | 0.066789 (rank : 174) | θ value | θ > 10 (rank : 151) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 942 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2 | Gene names | Aatk, Kiaa0641 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase). |
SH3K1_MOUSE
|
||||||
NC score | 0.066613 (rank : 175) | θ value | θ > 10 (rank : 347) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 332 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3 | Gene names | Sh3kbp1, Ruk, Seta | |||
Domain Architecture |
|
|||||
Description | SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk). |
MERTK_MOUSE
|
||||||
NC score | 0.066507 (rank : 176) | θ value | θ > 10 (rank : 284) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 974 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q60805, Q62194 | Gene names | Mertk, Mer | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). |
FAK2_HUMAN
|
||||||
NC score | 0.066504 (rank : 177) | θ value | θ > 10 (rank : 229) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q14289, Q13475, Q14290, Q16709 | Gene names | PTK2B, FAK2, PYK2, RAFTK | |||
Domain Architecture |
|
|||||
Description | Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK). |
M3KL4_HUMAN
|
||||||
NC score | 0.066344 (rank : 178) | θ value | θ > 10 (rank : 282) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1087 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1 | Gene names | MLK4, KIAA1804 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4). |
STAM2_MOUSE
|
||||||
NC score | 0.066276 (rank : 179) | θ value | θ > 10 (rank : 373) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 285 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O88811, Q8C8Y4 | Gene names | Stam2, Hbp | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein). |
FLT3_MOUSE
|
||||||
NC score | 0.066239 (rank : 180) | θ value | θ > 10 (rank : 241) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q00342 | Gene names | Flt3, Flk-2, Flt-3 | |||
Domain Architecture |
|
|||||
Description | FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen). |
RAD21_MOUSE
|
||||||
NC score | 0.066130 (rank : 181) | θ value | 0.279714 (rank : 68) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 59 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q61550, P70219, Q91VB9, Q9DBU4 | Gene names | Rad21, Hr21 | |||
Domain Architecture |
|
|||||
Description | Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog). |
FAK2_MOUSE
|
||||||
NC score | 0.065957 (rank : 182) | θ value | θ > 10 (rank : 230) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 851 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9QVP9 | Gene names | Ptk2b, Fak2, Pyk2, Raftk | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK). |
DNMBP_MOUSE
|
||||||
NC score | 0.065943 (rank : 183) | θ value | θ > 10 (rank : 189) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 435 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2 | Gene names | Dnmbp, Kiaa1010 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Dynamin-binding protein (Scaffold protein Tuba). |
FLT3_HUMAN
|
||||||
NC score | 0.065935 (rank : 184) | θ value | θ > 10 (rank : 240) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 843 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P36888, Q13414 | Gene names | FLT3, STK1 | |||
Domain Architecture |
|
|||||
Description | FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen). |
UFO_HUMAN
|
||||||
NC score | 0.065622 (rank : 185) | θ value | θ > 10 (rank : 395) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 981 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | P30530 | Gene names | AXL, UFO | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene). |
IGF1R_MOUSE
|
||||||
NC score | 0.065528 (rank : 186) | θ value | θ > 10 (rank : 254) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 973 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q60751, O70438, Q62123 | Gene names | Igf1r | |||
Domain Architecture |
|
|||||
Description | Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]. |
M3K11_HUMAN
|
||||||
NC score | 0.065521 (rank : 187) | θ value | θ > 10 (rank : 280) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1136 | Shared Neighborhood Hits | 55 | |
SwissProt Accessions | Q16584, Q6P2G4 | Gene names | MAP3K11, MLK3, SPRK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase). |
IGF1R_HUMAN
|
||||||
NC score | 0.065513 (rank : 188) | θ value | θ > 10 (rank : 253) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 977 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P08069 | Gene names | IGF1R | |||
Domain Architecture |
|
|||||
Description | Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]. |
RPGF3_HUMAN
|
||||||
NC score | 0.065251 (rank : 189) | θ value | 1.06291 (rank : 87) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 56 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | O95398, O95634, Q8WVN0 | Gene names | RAPGEF3, CGEF1, EPAC, EPAC1 | |||
Domain Architecture |
|
|||||
Description | Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP). |
TNK1_HUMAN
|
||||||
NC score | 0.065157 (rank : 190) | θ value | θ > 10 (rank : 387) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 815 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q13470, O95364, Q8IYI4 | Gene names | TNK1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1). |
AATK_HUMAN
|
||||||
NC score | 0.065134 (rank : 191) | θ value | θ > 10 (rank : 150) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1243 | Shared Neighborhood Hits | 40 | |
SwissProt Accessions | Q6ZMQ8, O75136, Q6ZN31, Q86X28 | Gene names | AATK, KIAA0641 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP). |
DDR1_MOUSE
|
||||||
NC score | 0.065126 (rank : 192) | θ value | θ > 10 (rank : 185) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 818 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q03146 | Gene names | Ddr1, Cak, Eddr1, Mpk6 | |||
Domain Architecture |
|
|||||
Description | Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen). |
ERBB2_HUMAN
|
||||||
NC score | 0.065031 (rank : 193) | θ value | θ > 10 (rank : 220) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1073 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | P04626, Q14256, Q6LDV1, Q9UMK4 | Gene names | ERBB2, HER2, NEU, NGL | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19). |
EPHAA_HUMAN
|
||||||
NC score | 0.064993 (rank : 194) | θ value | θ > 10 (rank : 208) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 960 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q5JZY3, Q6NW42 | Gene names | EPHA10 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Ephrin type-A receptor 10 precursor (EC 2.7.10.1). |
DDR1_HUMAN
|
||||||
NC score | 0.064964 (rank : 195) | θ value | θ > 10 (rank : 184) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 819 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q08345, Q14196, Q16562, Q5ST12, Q9UD37 | Gene names | DDR1, CAK, EDDR1, RTK6, TRKE | |||
Domain Architecture |
|
|||||
Description | Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen). |
CSF1R_HUMAN
|
||||||
NC score | 0.064921 (rank : 196) | θ value | θ > 10 (rank : 181) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 943 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P07333, Q6LDW5, Q6LDY4 | Gene names | CSF1R, FMS | |||
Domain Architecture |
|
|||||
Description | Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen). |
TNK1_MOUSE
|
||||||
NC score | 0.064900 (rank : 197) | θ value | θ > 10 (rank : 388) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 806 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q99ML2, Q8CCC4, Q8K0X9, Q91V11 | Gene names | Tnk1, Kos1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells). |
UFO_MOUSE
|
||||||
NC score | 0.064742 (rank : 198) | θ value | θ > 10 (rank : 396) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q00993 | Gene names | Axl, Ark, Ufo | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase). |
ROR2_MOUSE
|
||||||
NC score | 0.064704 (rank : 199) | θ value | θ > 10 (rank : 335) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1000 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9Z138 | Gene names | Ror2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2). |
NTRK1_HUMAN
|
||||||
NC score | 0.064655 (rank : 200) | θ value | θ > 10 (rank : 299) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1023 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7 | Gene names | NTRK1, TRK | |||
Domain Architecture |
|
|||||
Description | High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A). |
PPIP1_MOUSE
|
||||||
NC score | 0.064585 (rank : 201) | θ value | θ > 10 (rank : 325) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 377 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | P97814, Q4V9R4 | Gene names | Pstpip1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1). |
INSRR_MOUSE
|
||||||
NC score | 0.064581 (rank : 202) | θ value | θ > 10 (rank : 259) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 961 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q9WTL4 | Gene names | Insrr, Irr | |||
Domain Architecture |
|
|||||
Description | Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]. |
ERBB3_MOUSE
|
||||||
NC score | 0.064566 (rank : 203) | θ value | θ > 10 (rank : 223) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 898 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317 | Gene names | Erbb3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor). |
INSRR_HUMAN
|
||||||
NC score | 0.064549 (rank : 204) | θ value | θ > 10 (rank : 258) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 950 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P14616, O60724 | Gene names | INSRR, IRR | |||
Domain Architecture |
|
|||||
Description | Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]. |
KIT_MOUSE
|
||||||
NC score | 0.064503 (rank : 205) | θ value | θ > 10 (rank : 272) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 949 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P05532, Q61415, Q61416, Q61417, Q6LEE9 | Gene names | Kit, Sl | |||
Domain Architecture |
|
|||||
Description | Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen). |
KIT_HUMAN
|
||||||
NC score | 0.064415 (rank : 206) | θ value | θ > 10 (rank : 271) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 953 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P10721, Q9UM99 | Gene names | KIT | |||
Domain Architecture |
|
|||||
Description | Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen). |
ERBB3_HUMAN
|
||||||
NC score | 0.064357 (rank : 207) | θ value | θ > 10 (rank : 222) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 918 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P21860 | Gene names | ERBB3, HER3 | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3). |
ERBB2_MOUSE
|
||||||
NC score | 0.064333 (rank : 208) | θ value | θ > 10 (rank : 221) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 918 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P70424, Q61525, Q6ZPE0 | Gene names | Erbb2, Kiaa3023, Neu | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene). |
FAK1_MOUSE
|
||||||
NC score | 0.064326 (rank : 209) | θ value | θ > 10 (rank : 228) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P34152, O08578 | Gene names | Ptk2, Fadk, Fak, Fak1 | |||
Domain Architecture |
|
|||||
Description | Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK). |
FAK1_HUMAN
|
||||||
NC score | 0.064290 (rank : 210) | θ value | θ > 10 (rank : 227) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q05397, Q14291, Q9UD85 | Gene names | PTK2, FAK, FAK1 | |||
Domain Architecture |
|
|||||
Description | Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2). |
CSF1R_MOUSE
|
||||||
NC score | 0.064241 (rank : 211) | θ value | θ > 10 (rank : 182) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 983 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P09581, Q3U3P1, Q9DBH9 | Gene names | Csf1r, Csfmr, Fms | |||
Domain Architecture |
|
|||||
Description | Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen). |
ERBB4_HUMAN
|
||||||
NC score | 0.064239 (rank : 212) | θ value | θ > 10 (rank : 224) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 910 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q15303 | Gene names | ERBB4, HER4 | |||
Domain Architecture |
|
|||||
Description | Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4). |
EPHB6_HUMAN
|
||||||
NC score | 0.064191 (rank : 213) | θ value | θ > 10 (rank : 216) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 912 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | O15197 | Gene names | EPHB6 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP). |
FGFR4_MOUSE
|
||||||
NC score | 0.064189 (rank : 214) | θ value | θ > 10 (rank : 238) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1026 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q03142, Q5J7D9, Q8C3V5, Q8CIB8 | Gene names | Fgfr4, Fgfr-4, Mpk-11 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen). |
RON_MOUSE
|
||||||
NC score | 0.064014 (rank : 215) | θ value | θ > 10 (rank : 331) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 836 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q62190, Q62555 | Gene names | Mst1r, Ron, Stk | |||
Domain Architecture |
|
|||||
Description | Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]. |
NCF1_HUMAN
|
||||||
NC score | 0.064010 (rank : 216) | θ value | θ > 10 (rank : 293) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 198 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2 | Gene names | NCF1 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2). |
TYRO3_MOUSE
|
||||||
NC score | 0.064009 (rank : 217) | θ value | θ > 10 (rank : 394) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1007 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87 | Gene names | Tyro3, Dtk, Rse | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3). |
EPHB6_MOUSE
|
||||||
NC score | 0.064004 (rank : 218) | θ value | θ > 10 (rank : 217) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 906 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O08644, Q8BN76, Q8K0A9 | Gene names | Ephb6, Cekl | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP). |
TYRO3_HUMAN
|
||||||
NC score | 0.063895 (rank : 219) | θ value | θ > 10 (rank : 393) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 995 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q06418, O14953, Q86VR3 | Gene names | TYRO3, BYK, DTK, RSE, SKY | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk). |
PGFRB_HUMAN
|
||||||
NC score | 0.063738 (rank : 220) | θ value | θ > 10 (rank : 320) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 962 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P09619, Q8N5L4 | Gene names | PDGFRB | |||
Domain Architecture |
|
|||||
Description | Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen). |
NCF1_MOUSE
|
||||||
NC score | 0.063650 (rank : 221) | θ value | θ > 10 (rank : 294) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 198 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q09014, O70144, Q9JI34 | Gene names | Ncf1 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K). |
M3K9_HUMAN
|
||||||
NC score | 0.063636 (rank : 222) | θ value | θ > 10 (rank : 281) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1123 | Shared Neighborhood Hits | 52 | |
SwissProt Accessions | P80192, Q6EH31, Q9H2N5 | Gene names | MAP3K9, MLK1, PRKE1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1). |
PGFRB_MOUSE
|
||||||
NC score | 0.063612 (rank : 223) | θ value | θ > 10 (rank : 321) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 960 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P05622 | Gene names | Pdgfrb, Pdgfr | |||
Domain Architecture |
|
|||||
Description | Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen). |
INSR_HUMAN
|
||||||
NC score | 0.063506 (rank : 224) | θ value | θ > 10 (rank : 260) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 963 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P06213 | Gene names | INSR | |||
Domain Architecture |
|
|||||
Description | Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta]. |
PGFRA_MOUSE
|
||||||
NC score | 0.063382 (rank : 225) | θ value | θ > 10 (rank : 319) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 975 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P26618, Q62046 | Gene names | Pdgfra | |||
Domain Architecture |
|
|||||
Description | Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen). |
RET_HUMAN
|
||||||
NC score | 0.063348 (rank : 226) | θ value | θ > 10 (rank : 327) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 873 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P07949, Q15250 | Gene names | RET | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret). |
DDR2_HUMAN
|
||||||
NC score | 0.063311 (rank : 227) | θ value | θ > 10 (rank : 186) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 818 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q16832 | Gene names | DDR2, NTRKR3, TKT, TYRO10 | |||
Domain Architecture |
|
|||||
Description | Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen). |
DDR2_MOUSE
|
||||||
NC score | 0.063249 (rank : 228) | θ value | θ > 10 (rank : 187) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 813 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q62371 | Gene names | Ddr2, Ntrkr3, Tkt, Tyro10 | |||
Domain Architecture |
|
|||||
Description | Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen). |
ROR2_HUMAN
|
||||||
NC score | 0.063236 (rank : 229) | θ value | θ > 10 (rank : 334) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1014 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61 | Gene names | ROR2, NTRKR2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2). |
ARHG7_MOUSE
|
||||||
NC score | 0.063194 (rank : 230) | θ value | θ > 10 (rank : 169) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 396 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q9ES28, O08757, Q9ES27 | Gene names | Arhgef7, Pak3bp | |||
Domain Architecture |
|
|||||
Description | Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR). |
PGFRA_HUMAN
|
||||||
NC score | 0.063176 (rank : 231) | θ value | θ > 10 (rank : 318) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 980 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P16234, Q96KZ7 | Gene names | PDGFRA | |||
Domain Architecture |
|
|||||
Description | Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen). |
TENS4_HUMAN
|
||||||
NC score | 0.063124 (rank : 232) | θ value | θ > 10 (rank : 379) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 214 | Shared Neighborhood Hits | 51 | |
SwissProt Accessions | Q8IZW8, Q71RB7, Q8WV64, Q96JV4 | Gene names | TNS4, CTEN | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-4 precursor (C-terminal tensin-like protein). |
FGFR4_HUMAN
|
||||||
NC score | 0.063080 (rank : 233) | θ value | θ > 10 (rank : 237) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1037 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P22455, O43785, Q14309 | Gene names | FGFR4, JTK2, TKF | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen). |
INSR_MOUSE
|
||||||
NC score | 0.063060 (rank : 234) | θ value | θ > 10 (rank : 261) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 968 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P15208 | Gene names | Insr | |||
Domain Architecture |
|
|||||
Description | Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta]. |
ROR1_MOUSE
|
||||||
NC score | 0.063035 (rank : 235) | θ value | θ > 10 (rank : 333) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1025 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q9Z139 | Gene names | Ror1, Ntrkr1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1). |
EGFR_MOUSE
|
||||||
NC score | 0.063021 (rank : 236) | θ value | θ > 10 (rank : 191) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 927 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q01279 | Gene names | Egfr | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor precursor (EC 2.7.10.1). |
NTRK3_HUMAN
|
||||||
NC score | 0.062929 (rank : 237) | θ value | θ > 10 (rank : 302) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1115 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q16288, Q12827, Q16289 | Gene names | NTRK3, TRKC | |||
Domain Architecture |
|
|||||
Description | NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C). |
ROR1_HUMAN
|
||||||
NC score | 0.062916 (rank : 238) | θ value | θ > 10 (rank : 332) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1018 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q01973, Q92776 | Gene names | ROR1, NTRKR1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1). |
RET_MOUSE
|
||||||
NC score | 0.062888 (rank : 239) | θ value | θ > 10 (rank : 328) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 884 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P35546, Q8BQ34, Q9QXH9 | Gene names | Ret | |||
Domain Architecture |
|
|||||
Description | Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret). |
RON_HUMAN
|
||||||
NC score | 0.062823 (rank : 240) | θ value | θ > 10 (rank : 330) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 842 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q04912 | Gene names | MST1R, RON | |||
Domain Architecture |
|
|||||
Description | Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]. |
EGFR_HUMAN
|
||||||
NC score | 0.062796 (rank : 241) | θ value | θ > 10 (rank : 190) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 939 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5 | Gene names | EGFR, ERBB1 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1). |
M3K10_HUMAN
|
||||||
NC score | 0.062716 (rank : 242) | θ value | θ > 10 (rank : 279) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1071 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q02779, Q12761, Q14871 | Gene names | MAP3K10, MLK2, MST | |||
Domain Architecture |
|
|||||
Description | Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST). |
EPHA1_MOUSE
|
||||||
NC score | 0.062459 (rank : 243) | θ value | θ > 10 (rank : 193) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 958 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q60750, Q8CED9, Q9ESJ2 | Gene names | Epha1, Esk | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK). |
ARHG7_HUMAN
|
||||||
NC score | 0.062432 (rank : 244) | θ value | θ > 10 (rank : 168) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 347 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1 | Gene names | ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85). |
MET_MOUSE
|
||||||
NC score | 0.062413 (rank : 245) | θ value | θ > 10 (rank : 286) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 844 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P16056, Q62125 | Gene names | Met | |||
Domain Architecture |
|
|||||
Description | Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met). |
MUSK_MOUSE
|
||||||
NC score | 0.062302 (rank : 246) | θ value | θ > 10 (rank : 292) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1057 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q61006, Q61005, Q61987, Q61988 | Gene names | Musk, Nsk2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK). |
MLKL_HUMAN
|
||||||
NC score | 0.062185 (rank : 247) | θ value | θ > 10 (rank : 287) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 600 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q8NB16, Q8N6V0 | Gene names | MLKL | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mixed lineage kinase domain-like protein. |
MET_HUMAN
|
||||||
NC score | 0.062125 (rank : 248) | θ value | θ > 10 (rank : 285) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 831 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P08581, O60366, Q12875, Q9UDX7, Q9UPL8 | Gene names | MET | |||
Domain Architecture |
|
|||||
Description | Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met). |
TIE1_HUMAN
|
||||||
NC score | 0.062098 (rank : 249) | θ value | θ > 10 (rank : 383) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1241 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P35590 | Gene names | TIE1, TIE | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1). |
MUSK_HUMAN
|
||||||
NC score | 0.061846 (rank : 250) | θ value | θ > 10 (rank : 291) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1074 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | O15146 | Gene names | MUSK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK). |
FGFR3_HUMAN
|
||||||
NC score | 0.061794 (rank : 251) | θ value | θ > 10 (rank : 235) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1042 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P22607, Q14308, Q16294, Q16608 | Gene names | FGFR3, JTK4 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). |
EPHA1_HUMAN
|
||||||
NC score | 0.061545 (rank : 252) | θ value | θ > 10 (rank : 192) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 997 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P21709, Q15405 | Gene names | EPHA1, EPH, EPHT, EPHT1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH). |
TIE1_MOUSE
|
||||||
NC score | 0.061534 (rank : 253) | θ value | θ > 10 (rank : 384) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1266 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q06806, Q811F4 | Gene names | Tie1, Tie, Tie-1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1). |
FGFR3_MOUSE
|
||||||
NC score | 0.061526 (rank : 254) | θ value | θ > 10 (rank : 236) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1059 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q61851, Q61564, Q63834 | Gene names | Fgfr3, Mfr3, Sam3 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen). |
EPHA6_HUMAN
|
||||||
NC score | 0.061477 (rank : 255) | θ value | θ > 10 (rank : 202) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 959 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9UF33 | Gene names | EPHA6, EHK2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2). |
EPHA6_MOUSE
|
||||||
NC score | 0.061326 (rank : 256) | θ value | θ > 10 (rank : 203) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 946 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q62413, Q8CCN2 | Gene names | Epha6, Ehk-2, Ehk2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2). |
FGFR2_MOUSE
|
||||||
NC score | 0.061073 (rank : 257) | θ value | θ > 10 (rank : 234) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1062 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P21803, O55141, Q00389, Q61342 | Gene names | Fgfr2, Bek, Ect1 | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen). |
FGFR2_HUMAN
|
||||||
NC score | 0.060900 (rank : 258) | θ value | θ > 10 (rank : 233) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1062 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0 | Gene names | FGFR2, BEK, KSAM | |||
Domain Architecture |
|
|||||
Description | Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen). |
EPHA5_MOUSE
|
||||||
NC score | 0.060772 (rank : 259) | θ value | θ > 10 (rank : 201) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 950 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q60629 | Gene names | Epha5, Bsk, Cek7, Ehk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7). |
ARHG6_HUMAN
|
||||||
NC score | 0.060761 (rank : 260) | θ value | θ > 10 (rank : 166) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 376 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q15052, Q15396, Q5JQ66, Q86XH0 | Gene names | ARHGEF6, COOL2, KIAA0006, PIXA | |||
Domain Architecture |
|
|||||
Description | Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2). |
FGFR1_MOUSE
|
||||||
NC score | 0.060620 (rank : 261) | θ value | θ > 10 (rank : 232) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1068 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P16092, Q01736, Q61562, Q80T10 | Gene names | Fgfr1, Flg | |||
Domain Architecture |
|
|||||
Description | Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen). |
FGFR1_HUMAN
|
||||||
NC score | 0.060592 (rank : 262) | θ value | θ > 10 (rank : 231) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1069 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685 | Gene names | FGFR1, FGFBR, FLG, FLT2 | |||
Domain Architecture |
|
|||||
Description | Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen). |
NTRK2_HUMAN
|
||||||
NC score | 0.060515 (rank : 263) | θ value | θ > 10 (rank : 300) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1081 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q16620, Q16675, Q8WXJ6 | Gene names | NTRK2, TRKB | |||
Domain Architecture |
|
|||||
Description | BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B). |
NTRK2_MOUSE
|
||||||
NC score | 0.060506 (rank : 264) | θ value | θ > 10 (rank : 301) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1088 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P15209, Q3TUF9, Q80WU0, Q91XJ9 | Gene names | Ntrk2, Trkb | |||
Domain Architecture |
|
|||||
Description | BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B). |
TIE2_MOUSE
|
||||||
NC score | 0.060304 (rank : 265) | θ value | θ > 10 (rank : 386) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1204 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q02858 | Gene names | Tek, Hyk, Tie-2, Tie2 | |||
Domain Architecture |
|
|||||
Description | Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen). |
EPHA2_HUMAN
|
||||||
NC score | 0.060257 (rank : 266) | θ value | θ > 10 (rank : 194) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1021 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29317 | Gene names | EPHA2, ECK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase). |
MLKL_MOUSE
|
||||||
NC score | 0.060176 (rank : 267) | θ value | θ > 10 (rank : 288) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 707 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9D2Y4, Q8CIJ5 | Gene names | Mlkl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mixed lineage kinase domain-like protein. |
HCLS1_HUMAN
|
||||||
NC score | 0.060173 (rank : 268) | θ value | θ > 10 (rank : 251) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 358 | Shared Neighborhood Hits | 39 | |
SwissProt Accessions | P14317 | Gene names | HCLS1, HS1 | |||
Domain Architecture |
|
|||||
Description | Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75). |
TIE2_HUMAN
|
||||||
NC score | 0.060169 (rank : 269) | θ value | θ > 10 (rank : 385) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1192 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q02763 | Gene names | TEK, TIE2 | |||
Domain Architecture |
|
|||||
Description | Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen). |
PACN2_HUMAN
|
||||||
NC score | 0.060077 (rank : 270) | θ value | θ > 10 (rank : 312) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 339 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2 | Gene names | PACSIN2 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 2. |
VGFR3_HUMAN
|
||||||
NC score | 0.060073 (rank : 271) | θ value | θ > 10 (rank : 402) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1037 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35916 | Gene names | FLT4 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4). |
HCLS1_MOUSE
|
||||||
NC score | 0.060014 (rank : 272) | θ value | θ > 10 (rank : 252) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 329 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | P49710 | Gene names | Hcls1, Hs1 | |||
Domain Architecture |
|
|||||
Description | Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1). |
EPHA2_MOUSE
|
||||||
NC score | 0.059783 (rank : 273) | θ value | θ > 10 (rank : 195) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1020 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q03145, Q60633, Q62212 | Gene names | Epha2, Eck, Sek2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2). |
EPHA8_MOUSE
|
||||||
NC score | 0.059659 (rank : 274) | θ value | θ > 10 (rank : 207) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 969 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | O09127 | Gene names | Epha8, Eek | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase). |
ARHG6_MOUSE
|
||||||
NC score | 0.059576 (rank : 275) | θ value | θ > 10 (rank : 167) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 394 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q8K4I3, Q8C9V4 | Gene names | Arhgef6 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6). |
EPHA8_HUMAN
|
||||||
NC score | 0.059507 (rank : 276) | θ value | θ > 10 (rank : 206) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 956 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29322, Q9NUA9, Q9P269 | Gene names | EPHA8, EEK, KIAA1459 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3). |
EPHB3_MOUSE
|
||||||
NC score | 0.059417 (rank : 277) | θ value | θ > 10 (rank : 213) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 996 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54754, Q62214 | Gene names | Ephb3, Etk2, Mdk5, Sek4 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4). |
EPHB3_HUMAN
|
||||||
NC score | 0.059384 (rank : 278) | θ value | θ > 10 (rank : 212) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 996 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54753, Q7Z740 | Gene names | EPHB3, ETK2, HEK2 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2). |
EPHB4_HUMAN
|
||||||
NC score | 0.059353 (rank : 279) | θ value | θ > 10 (rank : 214) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1056 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P54760, Q9BTA5, Q9BXP0 | Gene names | EPHB4, HTK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK). |
PTK7_HUMAN
|
||||||
NC score | 0.059272 (rank : 280) | θ value | θ > 10 (rank : 326) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q13308, Q13417 | Gene names | PTK7, CCK4 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4). |
PACN1_HUMAN
|
||||||
NC score | 0.059098 (rank : 281) | θ value | θ > 10 (rank : 310) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 320 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9BY11, Q9P2G8 | Gene names | PACSIN1, KIAA1379 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 1. |
VGFR3_MOUSE
|
||||||
NC score | 0.059066 (rank : 282) | θ value | θ > 10 (rank : 403) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1056 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35917 | Gene names | Flt4, Flt-4 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4). |
VGFR2_HUMAN
|
||||||
NC score | 0.059014 (rank : 283) | θ value | θ > 10 (rank : 400) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P35968, O60723, Q14178 | Gene names | KDR, FLK1 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen). |
EPHB2_MOUSE
|
||||||
NC score | 0.058851 (rank : 284) | θ value | θ > 10 (rank : 211) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 982 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54763, Q62213, Q9QVY4 | Gene names | Ephb2, Epth3, Nuk, Sek3 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3). |
VGFR2_MOUSE
|
||||||
NC score | 0.058845 (rank : 285) | θ value | θ > 10 (rank : 401) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1089 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P35918 | Gene names | Kdr, Flk-1, Flk1 | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen). |
EPHB2_HUMAN
|
||||||
NC score | 0.058833 (rank : 286) | θ value | θ > 10 (rank : 210) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 983 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8 | Gene names | EPHB2, DRT, EPTH3, ERK, HEK5 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen). |
EPHA4_HUMAN
|
||||||
NC score | 0.058830 (rank : 287) | θ value | θ > 10 (rank : 198) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 975 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54764 | Gene names | EPHA4, HEK8, SEK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8). |
EPHA4_MOUSE
|
||||||
NC score | 0.058821 (rank : 288) | θ value | θ > 10 (rank : 199) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 982 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q03137 | Gene names | Epha4, Sek, Sek1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3). |
EPHA3_MOUSE
|
||||||
NC score | 0.058795 (rank : 289) | θ value | θ > 10 (rank : 197) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29319 | Gene names | Epha3, Etk1, Mek4, Tyro4 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4). |
EPHB4_MOUSE
|
||||||
NC score | 0.058661 (rank : 290) | θ value | θ > 10 (rank : 215) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1013 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P54761, Q60627 | Gene names | Ephb4, Htk, Mdk2, Myk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1). |
JAK1_MOUSE
|
||||||
NC score | 0.058650 (rank : 291) | θ value | θ > 10 (rank : 266) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 854 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P52332, Q62126 | Gene names | Jak1 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1). |
EPHB1_HUMAN
|
||||||
NC score | 0.058578 (rank : 292) | θ value | θ > 10 (rank : 209) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 988 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P54762, O43569, O95142, O95143 | Gene names | EPHB1, EPHT2, NET | |||
Domain Architecture |
|
|||||
Description | Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK). |
EPHA3_HUMAN
|
||||||
NC score | 0.058559 (rank : 293) | θ value | θ > 10 (rank : 196) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1005 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P29320, Q9H2V3, Q9H2V4 | Gene names | EPHA3, ETK, ETK1, HEK | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4). |
OSTF1_HUMAN
|
||||||
NC score | 0.058378 (rank : 294) | θ value | θ > 10 (rank : 303) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 466 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q92882, Q5W126, Q96IJ4 | Gene names | OSTF1 | |||
Domain Architecture |
|
|||||
Description | Osteoclast-stimulating factor 1. |
EPHA5_HUMAN
|
||||||
NC score | 0.058197 (rank : 295) | θ value | θ > 10 (rank : 200) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1009 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P54756 | Gene names | EPHA5, EHK1, HEK7 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7). |
EPHA7_HUMAN
|
||||||
NC score | 0.058143 (rank : 296) | θ value | θ > 10 (rank : 204) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1053 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124 | Gene names | EPHA7, EHK3, HEK11 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11). |
PACN3_MOUSE
|
||||||
NC score | 0.058075 (rank : 297) | θ value | θ > 10 (rank : 315) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 380 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q99JB8, Q9EQP9 | Gene names | Pacsin3 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase II substrate protein 3. |
EPHA7_MOUSE
|
||||||
NC score | 0.058053 (rank : 298) | θ value | θ > 10 (rank : 205) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1025 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q61772, Q61505, Q61773, Q61774 | Gene names | Epha7, Ebk, Ehk3, Mdk1 | |||
Domain Architecture |
|
|||||
Description | Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1). |
SRC8_HUMAN
|
||||||
NC score | 0.057885 (rank : 299) | θ value | θ > 10 (rank : 362) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 269 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q14247 | Gene names | CTTN, EMS1 | |||
Domain Architecture |
|
|||||
Description | Src substrate cortactin (Amplaxin) (Oncogene EMS1). |
JAK1_HUMAN
|
||||||
NC score | 0.057804 (rank : 300) | θ value | θ > 10 (rank : 265) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 858 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | P23458 | Gene names | JAK1, JAK1A | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1). |
SOCS1_HUMAN
|
||||||
NC score | 0.057486 (rank : 301) | θ value | θ > 10 (rank : 351) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 79 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O15524, O15097, Q9NSA7 | Gene names | SOCS1, SSI1, TIP3 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3). |
PACN1_MOUSE
|
||||||
NC score | 0.057285 (rank : 302) | θ value | θ > 10 (rank : 311) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 283 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q61644 | Gene names | Pacsin1, Pacsin | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 1. |
PACN2_MOUSE
|
||||||
NC score | 0.057135 (rank : 303) | θ value | θ > 10 (rank : 313) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 382 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | Q9WVE8 | Gene names | Pacsin2 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 2. |
VGFR1_HUMAN
|
||||||
NC score | 0.056883 (rank : 304) | θ value | θ > 10 (rank : 398) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1109 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P17948, O60722, P16057, Q12954 | Gene names | FLT1, FLT, FRT | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1). |
VGFR1_MOUSE
|
||||||
NC score | 0.056792 (rank : 305) | θ value | θ > 10 (rank : 399) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1118 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | P35969, O55094, Q61517 | Gene names | Flt1, Emrk2, Flt | |||
Domain Architecture |
|
|||||
Description | Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2). |
PEX13_HUMAN
|
||||||
NC score | 0.056573 (rank : 306) | θ value | θ > 10 (rank : 316) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 128 | Shared Neighborhood Hits | 20 | |
SwissProt Accessions | Q92968 | Gene names | PEX13 | |||
Domain Architecture |
|
|||||
Description | Peroxisomal membrane protein PEX13 (Peroxin-13). |
SRC8_MOUSE
|
||||||
NC score | 0.056521 (rank : 307) | θ value | θ > 10 (rank : 363) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 292 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q60598 | Gene names | Cttn, Ems1 | |||
Domain Architecture |
|
|||||
Description | Src substrate cortactin. |
JAK3_HUMAN
|
||||||
NC score | 0.056206 (rank : 308) | θ value | θ > 10 (rank : 269) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 827 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P52333, Q13259, Q13260, Q13611, Q9Y6S2 | Gene names | JAK3 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK). |
ANPRA_HUMAN
|
||||||
NC score | 0.056196 (rank : 309) | θ value | θ > 10 (rank : 161) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 612 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P16066, Q6P4Q3 | Gene names | NPR1, ANPRA | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor). |
SOCS1_MOUSE
|
||||||
NC score | 0.056184 (rank : 310) | θ value | θ > 10 (rank : 352) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 82 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O35716, O35960, Q3U3L0 | Gene names | Socs1, Cish1, Ssi1 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1). |
OSTF1_MOUSE
|
||||||
NC score | 0.055943 (rank : 311) | θ value | θ > 10 (rank : 304) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 467 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q62422, Q3UF05 | Gene names | Ostf1, Sh3d3, Sh3p2 | |||
Domain Architecture |
|
|||||
Description | Osteoclast-stimulating factor 1 (SH3 domain protein 3). |
PACN3_HUMAN
|
||||||
NC score | 0.055783 (rank : 312) | θ value | θ > 10 (rank : 314) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 385 | Shared Neighborhood Hits | 35 | |
SwissProt Accessions | Q9UKS6, Q9H331, Q9NWV9 | Gene names | PACSIN3 | |||
Domain Architecture |
|
|||||
Description | Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I). |
TENS1_HUMAN
|
||||||
NC score | 0.055698 (rank : 313) | θ value | θ > 10 (rank : 378) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 400 | Shared Neighborhood Hits | 53 | |
SwissProt Accessions | Q9HBL0 | Gene names | TNS1, TNS | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Tensin-1. |
GUC2F_HUMAN
|
||||||
NC score | 0.055683 (rank : 314) | θ value | θ > 10 (rank : 248) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 740 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P51841, Q9UJF1 | Gene names | GUCY2F, GUC2F, RETGC2 | |||
Domain Architecture |
|
|||||
Description | Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F). |
ANPRA_MOUSE
|
||||||
NC score | 0.055654 (rank : 315) | θ value | θ > 10 (rank : 162) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 600 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P18293 | Gene names | Npr1, Npra | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor). |
ABI3_HUMAN
|
||||||
NC score | 0.055062 (rank : 316) | θ value | θ > 10 (rank : 154) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q9P2A4, Q9H0P6 | Gene names | ABI3, NESH | |||
Domain Architecture |
No domain graphic available |
|||||
Description | ABI gene family member 3 (New molecule including SH3) (Nesh). |
JAK2_MOUSE
|
||||||
NC score | 0.054953 (rank : 317) | θ value | θ > 10 (rank : 268) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 839 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q62120, Q62124 | Gene names | Jak2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2). |
TYK2_MOUSE
|
||||||
NC score | 0.054794 (rank : 318) | θ value | θ > 10 (rank : 392) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 850 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9R117, O88431, Q8VE41 | Gene names | Tyk2 | |||
Domain Architecture |
|
|||||
Description | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2). |
EPS8_HUMAN
|
||||||
NC score | 0.054651 (rank : 319) | θ value | θ > 10 (rank : 218) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 151 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q12929, Q8N6J0 | Gene names | EPS8 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor kinase substrate 8. |
JAK2_HUMAN
|
||||||
NC score | 0.054461 (rank : 320) | θ value | θ > 10 (rank : 267) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 847 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | O60674, O14636, O75297 | Gene names | JAK2 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2). |
SH3G3_MOUSE
|
||||||
NC score | 0.054192 (rank : 321) | θ value | θ > 10 (rank : 345) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 236 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q62421 | Gene names | Sh3gl3, Sh3d2c, Sh3d2c2 | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13). |
ILK_MOUSE
|
||||||
NC score | 0.054063 (rank : 322) | θ value | θ > 10 (rank : 257) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 858 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | O55222 | Gene names | Ilk | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase (EC 2.7.11.1). |
TYK2_HUMAN
|
||||||
NC score | 0.053946 (rank : 323) | θ value | θ > 10 (rank : 391) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 841 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | P29597, Q6QB10, Q96CH0 | Gene names | TYK2 | |||
Domain Architecture |
|
|||||
Description | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2). |
SH3G2_HUMAN
|
||||||
NC score | 0.053710 (rank : 324) | θ value | θ > 10 (rank : 343) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 324 | Shared Neighborhood Hits | 33 | |
SwissProt Accessions | Q99962, Q9NQK5 | Gene names | SH3GL2, CNSA2, SH3D2A | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1). |
JAK3_MOUSE
|
||||||
NC score | 0.053669 (rank : 325) | θ value | θ > 10 (rank : 270) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 821 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q62137, Q61746, Q61747 | Gene names | Jak3 | |||
Domain Architecture |
|
|||||
Description | Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3). |
ILK1_HUMAN
|
||||||
NC score | 0.053547 (rank : 326) | θ value | θ > 10 (rank : 255) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 857 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q13418 | Gene names | ILK, ILK1 | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK). |
GUC2C_HUMAN
|
||||||
NC score | 0.053461 (rank : 327) | θ value | θ > 10 (rank : 247) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 624 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | P25092 | Gene names | GUCY2C, GUC2C, STAR | |||
Domain Architecture |
|
|||||
Description | Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR). |
SOCS4_MOUSE
|
||||||
NC score | 0.053355 (rank : 328) | θ value | θ > 10 (rank : 358) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 69 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q91ZA6 | Gene names | Socs4, Socs7 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7). |
SH3G3_HUMAN
|
||||||
NC score | 0.053084 (rank : 329) | θ value | θ > 10 (rank : 344) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 222 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q99963, O43553, O43554 | Gene names | SH3GL3, CNSA3, SH3D2C | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2). |
ILK2_HUMAN
|
||||||
NC score | 0.053053 (rank : 330) | θ value | θ > 10 (rank : 256) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 848 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | P57043 | Gene names | ILK2 | |||
Domain Architecture |
|
|||||
Description | Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2). |
RHG04_HUMAN
|
||||||
NC score | 0.053009 (rank : 331) | θ value | θ > 10 (rank : 329) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | P98171, Q14144 | Gene names | ARHGAP4, KIAA0131, RGC1, RHOGAP4 | |||
Domain Architecture |
|
|||||
Description | Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115). |
SOCS4_HUMAN
|
||||||
NC score | 0.052788 (rank : 332) | θ value | θ > 10 (rank : 357) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 69 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q8WXH5 | Gene names | SOCS4, SOCS7 | |||
Domain Architecture |
|
|||||
Description | Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7). |
TEX14_MOUSE
|
||||||
NC score | 0.052695 (rank : 333) | θ value | θ > 10 (rank : 382) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1333 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8 | Gene names | Tex14 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Testis-expressed protein 14 (Testis-expressed sequence 14). |
SH3G1_MOUSE
|
||||||
NC score | 0.052616 (rank : 334) | θ value | θ > 10 (rank : 342) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 291 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | Q62419 | Gene names | Sh3gl1, Sh3d2b | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8). |
CIP4_HUMAN
|
||||||
NC score | 0.052461 (rank : 335) | θ value | θ > 10 (rank : 178) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 374 | Shared Neighborhood Hits | 22 | |
SwissProt Accessions | Q15642, O15184, Q5TZN1 | Gene names | TRIP10, CIP4 | |||
Domain Architecture |
|
|||||
Description | Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10). |
ABI2_HUMAN
|
||||||
NC score | 0.052414 (rank : 336) | θ value | θ > 10 (rank : 152) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 350 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q9NYB9, Q13147, Q13249, Q13801, Q9BV70 | Gene names | ABI2, ARGBPIA | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1). |
ANPRB_MOUSE
|
||||||
NC score | 0.052015 (rank : 337) | θ value | θ > 10 (rank : 164) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 607 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9 | Gene names | Npr2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor). |
AHI1_MOUSE
|
||||||
NC score | 0.051890 (rank : 338) | θ value | θ > 10 (rank : 158) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 496 | Shared Neighborhood Hits | 36 | |
SwissProt Accessions | Q8K3E5, Q7TNV2, Q9CVY1 | Gene names | Ahi1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Jouberin (Abelson helper integration site 1 protein) (AHI-1). |
ANPRB_HUMAN
|
||||||
NC score | 0.051859 (rank : 339) | θ value | θ > 10 (rank : 163) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 646 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | P20594, O60871, Q9UQ50 | Gene names | NPR2, ANPRB | |||
Domain Architecture |
|
|||||
Description | Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor). |
PEX13_MOUSE
|
||||||
NC score | 0.051797 (rank : 340) | θ value | θ > 10 (rank : 317) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 19 | |
SwissProt Accessions | Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1 | Gene names | Pex13 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Peroxisomal membrane protein PEX13 (Peroxin-13). |
ES8L3_MOUSE
|
||||||
NC score | 0.051637 (rank : 341) | θ value | θ > 10 (rank : 226) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 168 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | Q91WL0, Q3TJ14 | Gene names | Eps8l3, Eps8r3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3). |
CT032_HUMAN
|
||||||
NC score | 0.051567 (rank : 342) | θ value | θ > 10 (rank : 183) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 235 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q9NQ75, Q96K09, Q9BYL5 | Gene names | HEFL, C20orf32 | |||
Domain Architecture |
|
|||||
Description | HEF-like protein. |
ABI2_MOUSE
|
||||||
NC score | 0.051542 (rank : 343) | θ value | θ > 10 (rank : 153) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 266 | Shared Neighborhood Hits | 31 | |
SwissProt Accessions | P62484, Q6PHU3 | Gene names | Abi2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Abl interactor 2 (Abelson interactor 2) (Abi-2). |
ARHG4_HUMAN
|
||||||
NC score | 0.051469 (rank : 344) | θ value | θ > 10 (rank : 165) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 242 | Shared Neighborhood Hits | 28 | |
SwissProt Accessions | Q9NR80, Q9HDC6, Q9UPP0 | Gene names | ARHGEF4, KIAA1112 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef). |
EPS8_MOUSE
|
||||||
NC score | 0.051378 (rank : 345) | θ value | θ > 10 (rank : 219) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 157 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q08509 | Gene names | Eps8 | |||
Domain Architecture |
|
|||||
Description | Epidermal growth factor receptor kinase substrate 8. |
TEX14_HUMAN
|
||||||
NC score | 0.051338 (rank : 346) | θ value | θ > 10 (rank : 381) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1103 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9 | Gene names | TEX14 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Testis-expressed protein 14 (Testis-expressed sequence 14). |
KSR2_HUMAN
|
||||||
NC score | 0.051281 (rank : 347) | θ value | θ > 10 (rank : 274) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 920 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q6VAB6, Q8N775 | Gene names | KSR2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Kinase suppressor of ras-2 (hKSR2). |
KSR1_HUMAN
|
||||||
NC score | 0.051013 (rank : 348) | θ value | θ > 10 (rank : 273) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 867 | Shared Neighborhood Hits | 29 | |
SwissProt Accessions | Q8IVT5, Q13476 | Gene names | KSR1, KSR | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Kinase suppressor of ras-1 (Kinase suppressor of ras). |
SH3G1_HUMAN
|
||||||
NC score | 0.050866 (rank : 349) | θ value | θ > 10 (rank : 341) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 307 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q99961, Q99668 | Gene names | SH3GL1, CNSA1, SH3D2B | |||
Domain Architecture |
|
|||||
Description | SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL). |
BRAF1_HUMAN
|
||||||
NC score | 0.050672 (rank : 350) | θ value | θ > 10 (rank : 173) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 883 | Shared Neighborhood Hits | 34 | |
SwissProt Accessions | P15056, Q13878, Q9Y6T3 | Gene names | BRAF, BRAF1, RAFB1 | |||
Domain Architecture |
|
|||||
Description | B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1). |
ITSN2_HUMAN
|
||||||
NC score | 0.050602 (rank : 351) | θ value | θ > 10 (rank : 264) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1173 | Shared Neighborhood Hits | 49 | |
SwissProt Accessions | Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4 | Gene names | ITSN2, KIAA1256, SH3D1B, SWAP | |||
Domain Architecture |
|
|||||
Description | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein). |
MLTK_HUMAN
|
||||||
NC score | 0.050586 (rank : 352) | θ value | θ > 10 (rank : 289) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 911 | Shared Neighborhood Hits | 27 | |
SwissProt Accessions | Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9 | Gene names | MLTK, ZAK | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein). |
TCGAP_HUMAN
|
||||||
NC score | 0.050572 (rank : 353) | θ value | 0.0961366 (rank : 64) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 872 | Shared Neighborhood Hits | 38 | |
SwissProt Accessions | O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23 | Gene names | SNX26, TCGAP | |||
Domain Architecture |
|
|||||
Description | TC10/CDC42 GTPase-activating protein (Sorting nexin-26). |
MLTK_MOUSE
|
||||||
NC score | 0.050533 (rank : 354) | θ value | θ > 10 (rank : 290) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 874 | Shared Neighborhood Hits | 26 | |
SwissProt Accessions | Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3 | Gene names | Mltk | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK). |
ABI3_MOUSE
|
||||||
NC score | 0.050504 (rank : 355) | θ value | θ > 10 (rank : 155) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 227 | Shared Neighborhood Hits | 30 | |
SwissProt Accessions | Q8BYZ1, Q6PE63, Q9D7S4 | Gene names | Abi3, Nesh | |||
Domain Architecture |
No domain graphic available |
|||||
Description | ABI gene family member 3 (New molecule including SH3) (Nesh). |
NCF4_MOUSE
|
||||||
NC score | 0.050150 (rank : 356) | θ value | θ > 10 (rank : 296) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 177 | Shared Neighborhood Hits | 23 | |
SwissProt Accessions | P97369 | Gene names | Ncf4 | |||
Domain Architecture |
|
|||||
Description | Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox). |
ES8L2_HUMAN
|
||||||
NC score | 0.050023 (rank : 357) | θ value | θ > 10 (rank : 225) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 193 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9 | Gene names | EPS8L2, EPS8R2 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2). |
MBD6_HUMAN
|
||||||
NC score | 0.047734 (rank : 358) | θ value | 0.365318 (rank : 72) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 349 | Shared Neighborhood Hits | 17 | |
SwissProt Accessions | Q96DN6, Q8N3M0, Q8NA81, Q96Q00 | Gene names | MBD6, KIAA1887 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6). |
RAI1_HUMAN
|
||||||
NC score | 0.047662 (rank : 359) | θ value | 0.279714 (rank : 69) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 360 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69 | Gene names | RAI1, KIAA1820 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Retinoic acid-induced protein 1. |
RAI1_MOUSE
|
||||||
NC score | 0.047211 (rank : 360) | θ value | 0.813845 (rank : 81) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 344 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | Q61818, Q6ZPH7, Q8CEV1 | Gene names | Rai1, Kiaa1820 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Retinoic acid-induced protein 1. |
DOT1L_HUMAN
|
||||||
NC score | 0.045358 (rank : 361) | θ value | 0.279714 (rank : 67) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 660 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | Q8TEK3, O60379, Q96JL1 | Gene names | DOT1L, KIAA1814 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein). |
SELPL_HUMAN
|
||||||
NC score | 0.044941 (rank : 362) | θ value | 3.0926 (rank : 111) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 68 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q14242, Q12775 | Gene names | SELPLG | |||
Domain Architecture |
No domain graphic available |
|||||
Description | P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen). |
SELPL_MOUSE
|
||||||
NC score | 0.043280 (rank : 363) | θ value | 0.365318 (rank : 73) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 588 | Shared Neighborhood Hits | 24 | |
SwissProt Accessions | Q62170 | Gene names | Selplg, Selp1, Selpl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand). |
B2L13_HUMAN
|
||||||
NC score | 0.043274 (rank : 364) | θ value | 0.365318 (rank : 71) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 57 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q9BXK5, Q96B37, Q96IB7, Q9BY01, Q9HC05, Q9UFE0, Q9UKN3 | Gene names | BCL2L13, MIL1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo). |
ASPP1_MOUSE
|
||||||
NC score | 0.039301 (rank : 365) | θ value | 8.99809 (rank : 142) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1244 | Shared Neighborhood Hits | 46 | |
SwissProt Accessions | Q62415 | Gene names | Ppp1r13b, Aspp1 | |||
Domain Architecture |
|
|||||
Description | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B). |
RIMB1_HUMAN
|
||||||
NC score | 0.036051 (rank : 366) | θ value | 1.81305 (rank : 101) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1479 | Shared Neighborhood Hits | 45 | |
SwissProt Accessions | O95153, O75111, Q8N5W3 | Gene names | BZRAP1, KIAA0612, RBP1 | |||
Domain Architecture |
|
|||||
Description | Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1). |
WNK2_HUMAN
|
||||||
NC score | 0.035896 (rank : 367) | θ value | 6.88961 (rank : 141) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1407 | Shared Neighborhood Hits | 50 | |
SwissProt Accessions | Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4 | Gene names | WNK2, KIAA1760, PRKWNK2 | |||
Domain Architecture |
|
|||||
Description | Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2). |
SON_HUMAN
|
||||||
NC score | 0.032436 (rank : 368) | θ value | 0.365318 (rank : 74) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1568 | Shared Neighborhood Hits | 44 | |
SwissProt Accessions | P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0 | Gene names | SON, C21orf50, DBP5, KIAA1019, NREBP | |||
Domain Architecture |
|
|||||
Description | SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1). |
FMNL_HUMAN
|
||||||
NC score | 0.029031 (rank : 369) | θ value | 1.06291 (rank : 84) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 529 | Shared Neighborhood Hits | 16 | |
SwissProt Accessions | O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10 | Gene names | FMNL1, C17orf1, C17orf1B, FMNL | |||
Domain Architecture |
|
|||||
Description | Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13). |
FMNL_MOUSE
|
||||||
NC score | 0.027368 (rank : 370) | θ value | 1.81305 (rank : 99) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 428 | Shared Neighborhood Hits | 12 | |
SwissProt Accessions | Q9JL26, Q6KAN4, Q9Z2V7 | Gene names | Fmnl1, Frl | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Formin-like protein 1 (Formin-related protein). |
MNT_MOUSE
|
||||||
NC score | 0.026760 (rank : 371) | θ value | 1.38821 (rank : 91) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 432 | Shared Neighborhood Hits | 15 | |
SwissProt Accessions | O08789, P97349 | Gene names | Mnt, Rox | |||
Domain Architecture |
|
|||||
Description | Max-binding protein MNT (Protein ROX) (Myc antagonist MNT). |
MLL3_HUMAN
|
||||||
NC score | 0.024971 (rank : 372) | θ value | 2.36792 (rank : 104) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1644 | Shared Neighborhood Hits | 37 | |
SwissProt Accessions | Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7 | Gene names | MLL3, HALR, KIAA1506 | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein). |
CS016_HUMAN
|
||||||
NC score | 0.024931 (rank : 373) | θ value | 5.27518 (rank : 126) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 310 | Shared Neighborhood Hits | 14 | |
SwissProt Accessions | Q8ND99 | Gene names | C19orf16 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Uncharacterized protein C19orf16. |
PODXL_MOUSE
|
||||||
NC score | 0.024445 (rank : 374) | θ value | 4.03905 (rank : 119) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 130 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q9R0M4, Q9ESZ1 | Gene names | Podxl, Pclp1 | |||
Domain Architecture |
|
|||||
Description | Podocalyxin-like protein 1 precursor. |
TIMD1_MOUSE
|
||||||
NC score | 0.024219 (rank : 375) | θ value | 1.38821 (rank : 95) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 97 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q5QNS5, Q7TPU2, Q8VIM1, Q8VIM2 | Gene names | Havcr1, Tim1, Timd1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Hepatitis A virus cellular receptor 1 homolog precursor (HAVcr-1) (T cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T cell membrane protein 1) (TIM-1). |
MEGF9_HUMAN
|
||||||
NC score | 0.022439 (rank : 376) | θ value | 0.0252991 (rank : 53) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 557 | Shared Neighborhood Hits | 12 | |
SwissProt Accessions | Q9H1U4, O75098 | Gene names | MEGF9, EGFL5, KIAA0818 | |||
Domain Architecture |
|
|||||
Description | Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5). |
BASP_HUMAN
|
||||||
NC score | 0.022030 (rank : 377) | θ value | 4.03905 (rank : 116) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 321 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | P80723, O43596, Q5U0S0 | Gene names | BASP1, NAP22 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein). |
MLL3_MOUSE
|
||||||
NC score | 0.021435 (rank : 378) | θ value | 5.27518 (rank : 128) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1399 | Shared Neighborhood Hits | 25 | |
SwissProt Accessions | Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6 | Gene names | Mll3 | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3). |
RTN4_MOUSE
|
||||||
NC score | 0.021435 (rank : 379) | θ value | 1.06291 (rank : 88) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 341 | Shared Neighborhood Hits | 10 | |
SwissProt Accessions | Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3 | Gene names | Rtn4, Kiaa0886, Nogo | |||
Domain Architecture |
|
|||||
Description | Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein). |
MLL2_HUMAN
|
||||||
NC score | 0.021364 (rank : 380) | θ value | 5.27518 (rank : 127) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1788 | Shared Neighborhood Hits | 32 | |
SwissProt Accessions | O14686, O14687 | Gene names | MLL2, ALR | |||
Domain Architecture |
|
|||||
Description | Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein). |
REL_HUMAN
|
||||||
NC score | 0.021048 (rank : 381) | θ value | 0.62314 (rank : 77) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 31 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | Q04864, Q2PNZ7, Q6LDY0 | Gene names | REL | |||
Domain Architecture |
|
|||||
Description | C-Rel proto-oncogene protein (C-Rel protein). |
TIRAP_HUMAN
|
||||||
NC score | 0.020690 (rank : 382) | θ value | 4.03905 (rank : 121) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 33 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P58753, Q8N5E5 | Gene names | TIRAP, MAL | |||
Domain Architecture |
|
|||||
Description | Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt). |
LIPS_MOUSE
|
||||||
NC score | 0.020035 (rank : 383) | θ value | 3.0926 (rank : 110) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 17 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P54310, P97866, Q3TE34, Q6GU16 | Gene names | Lipe | |||
Domain Architecture |
|
|||||
Description | Hormone-sensitive lipase (EC 3.1.1.79) (HSL). |
SNPC4_MOUSE
|
||||||
NC score | 0.019378 (rank : 384) | θ value | 4.03905 (rank : 120) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 237 | Shared Neighborhood Hits | 13 | |
SwissProt Accessions | Q8BP86, Q6PGG7, Q80UG9, Q810L1 | Gene names | Snapc4 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit). |
RERE_HUMAN
|
||||||
NC score | 0.017983 (rank : 385) | θ value | 5.27518 (rank : 130) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 779 | Shared Neighborhood Hits | 19 | |
SwissProt Accessions | Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4 | Gene names | RERE, ARG, ARP, ATN1L, KIAA0458 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein). |
ST5_MOUSE
|
||||||
NC score | 0.016508 (rank : 386) | θ value | 1.06291 (rank : 89) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 126 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q924W7, Q78H54, Q8K2P3, Q924W8 | Gene names | St5, Dennd2b | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Suppression of tumorigenicity 5 (DENN domain-containing protein 2B). |
PLCB3_HUMAN
|
||||||
NC score | 0.016402 (rank : 387) | θ value | 1.06291 (rank : 86) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 445 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q01970 | Gene names | PLCB3 | |||
Domain Architecture |
|
|||||
Description | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3). |
RERE_MOUSE
|
||||||
NC score | 0.016381 (rank : 388) | θ value | 8.99809 (rank : 148) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 785 | Shared Neighborhood Hits | 21 | |
SwissProt Accessions | Q80TZ9 | Gene names | Rere, Atr2, Kiaa0458 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Arginine-glutamic acid dipeptide repeats protein (Atrophin-2). |
BAT3_MOUSE
|
||||||
NC score | 0.014753 (rank : 389) | θ value | 8.99809 (rank : 143) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 518 | Shared Neighborhood Hits | 18 | |
SwissProt Accessions | Q9Z1R2, Q8SNA3 | Gene names | Bat3 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Large proline-rich protein BAT3 (HLA-B-associated transcript 3). |
MUC2_HUMAN
|
||||||
NC score | 0.012936 (rank : 390) | θ value | 4.03905 (rank : 117) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 906 | Shared Neighborhood Hits | 17 | |
SwissProt Accessions | Q02817, Q14878 | Gene names | MUC2, SMUC | |||
Domain Architecture |
|
|||||
Description | Mucin-2 precursor (Intestinal mucin-2). |
ZYX_HUMAN
|
||||||
NC score | 0.012645 (rank : 391) | θ value | 1.38821 (rank : 96) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 387 | Shared Neighborhood Hits | 11 | |
SwissProt Accessions | Q15942 | Gene names | ZYX | |||
Domain Architecture |
|
|||||
Description | Zyxin (Zyxin-2). |
FGRL1_HUMAN
|
||||||
NC score | 0.012191 (rank : 392) | θ value | 0.813845 (rank : 78) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 335 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q8N441, Q6PJN1, Q9BXN7, Q9H4D7 | Gene names | FGFRL1, FGFR5, FHFR | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor). |
HCFC1_MOUSE
|
||||||
NC score | 0.011841 (rank : 393) | θ value | 6.88961 (rank : 136) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 348 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2 | Gene names | Hcfc1 | |||
Domain Architecture |
No domain graphic available |
|||||
Description | Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]. |
B4GN1_HUMAN
|
||||||
NC score | 0.011006 (rank : 394) | θ value | 6.88961 (rank : 134) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 13 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | Q00973 | Gene names | B4GALNT1, GALGT, SIAT2 | |||
Domain Architecture |
|
|||||
Description | Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T). |
ROBO3_MOUSE
|
||||||
NC score | 0.010109 (rank : 395) | θ value | 0.813845 (rank : 82) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 524 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q9Z2I4 | Gene names | Robo3, Rbig1 | |||
Domain Architecture |
|
|||||
Description | Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1). |
SAFB1_HUMAN
|
||||||
NC score | 0.009975 (rank : 396) | θ value | 6.88961 (rank : 138) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 493 | Shared Neighborhood Hits | 7 | |
SwissProt Accessions | Q15424, O60406, Q59HH8 | Gene names | SAFB, HAP, HET, SAFB1 | |||
Domain Architecture |
|
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Description | Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein). |
PCNT_HUMAN
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NC score | 0.008209 (rank : 397) | θ value | 1.38821 (rank : 93) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 1551 | Shared Neighborhood Hits | 21 | |
SwissProt Accessions | O95613, O43152, Q7Z7C9 | Gene names | PCNT, KIAA0402, PCNT2 | |||
Domain Architecture |
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Description | Pericentrin (Pericentrin B) (Kendrin). |
SAFB2_HUMAN
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NC score | 0.007700 (rank : 398) | θ value | 6.88961 (rank : 139) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 720 | Shared Neighborhood Hits | 8 | |
SwissProt Accessions | Q14151, Q8TB13 | Gene names | SAFB2, KIAA0138 | |||
Domain Architecture |
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Description | Scaffold attachment factor B2. |
NKX24_MOUSE
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NC score | 0.006876 (rank : 399) | θ value | 1.81305 (rank : 100) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 356 | Shared Neighborhood Hits | 5 | |
SwissProt Accessions | Q9EQM3, Q9EQM4 | Gene names | Nkx2-4, Nkx2d | |||
Domain Architecture |
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Description | Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D). |
CALX_HUMAN
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NC score | 0.006369 (rank : 400) | θ value | 8.99809 (rank : 144) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 96 | Shared Neighborhood Hits | 3 | |
SwissProt Accessions | P27824 | Gene names | CANX | |||
Domain Architecture |
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Description | Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90). |
MSX1_HUMAN
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NC score | 0.006174 (rank : 401) | θ value | 1.38821 (rank : 92) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 374 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | P28360, Q96NY4 | Gene names | MSX1, HOX7 | |||
Domain Architecture |
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Description | Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7). |
ROBO3_HUMAN
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NC score | 0.005354 (rank : 402) | θ value | 6.88961 (rank : 137) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 570 | Shared Neighborhood Hits | 6 | |
SwissProt Accessions | Q96MS0 | Gene names | ROBO3 | |||
Domain Architecture |
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Description | Roundabout homolog 3 precursor (Roundabout-like protein 3). |
AGRIN_HUMAN
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NC score | 0.004557 (rank : 403) | θ value | 6.88961 (rank : 132) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 582 | Shared Neighborhood Hits | 9 | |
SwissProt Accessions | O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4 | Gene names | AGRIN, AGRN | |||
Domain Architecture |
No domain graphic available |
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Description | Agrin precursor. |
ANR38_HUMAN
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NC score | 0.003641 (rank : 404) | θ value | 6.88961 (rank : 133) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 443 | Shared Neighborhood Hits | 4 | |
SwissProt Accessions | Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3 | Gene names | ANKRD38 | |||
Domain Architecture |
No domain graphic available |
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Description | Ankyrin repeat domain-containing protein 38. |
ZNF31_HUMAN
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NC score | -0.004964 (rank : 405) | θ value | 5.27518 (rank : 131) | |||
Query Neighborhood Hits | 149 | Target Neighborhood Hits | 769 | Shared Neighborhood Hits | 2 | |
SwissProt Accessions | P17040, Q96H84 | Gene names | ZNF31, KOX29, ZNF360, ZSCAN20 | |||
Domain Architecture |
No domain graphic available |
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Description | Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360). |