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Network neighborhood for query Sequence : MSH5_HUMAN

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MSH5_HUMAN
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MSH5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

MSH5_MOUSE
θ value	0 (rank : 2)	NC score	0.998423 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUM7, Q9Z1Q6	Gene names	Msh5
Domain Architecture	No domain graphic available
Description	MutS protein homolog 5.

MSH3_HUMAN
θ value	4.86918e-46 (rank : 3)	NC score	0.828198 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

MSH3_MOUSE
θ value	6.15952e-41 (rank : 4)	NC score	0.822937 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P13705	Gene names	Msh3, Rep-3
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Repair-3 protein) (REP-1).

MSH2_MOUSE
θ value	3.16345e-37 (rank : 5)	NC score	0.805653 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P43247	Gene names	Msh2
Domain Architecture
Description	DNA mismatch repair protein Msh2 (MutS protein homolog 2).

MSH4_MOUSE
θ value	1.12514e-34 (rank : 6)	NC score	0.798839 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

MSH2_HUMAN
θ value	1.46948e-34 (rank : 7)	NC score	0.799587 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P43246, O75488	Gene names	MSH2
Domain Architecture
Description	DNA mismatch repair protein Msh2 (MutS protein homolog 2).

MSH4_HUMAN
θ value	5.584e-34 (rank : 8)	NC score	0.800886 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	O15457, Q8NEB3, Q9UNP8	Gene names	MSH4
Domain Architecture
Description	MutS protein homolog 4.

MSH6_MOUSE
θ value	1.24399e-33 (rank : 9)	NC score	0.763835 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_HUMAN
θ value	1.16434e-31 (rank : 10)	NC score	0.754730 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

CP250_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.009162 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	1805	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

HCN2_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.012497 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MEP1B_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.021867 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

NASP_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.031034 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ABCB9_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.006003 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

CBS_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.036123 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

MMP15_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.004834 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

HXA4_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.002008 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

INVS_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.004382 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	609	Shared Neighborhood Hits	4
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CSAD_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.006722 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

INVS_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.004095 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

MEP1B_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.015469 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

ZCPW1_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.054223 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

Hits sorted by NC score

MSH5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

MSH5_MOUSE
NC score	0.998423 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUM7, Q9Z1Q6	Gene names	Msh5
Domain Architecture	No domain graphic available
Description	MutS protein homolog 5.

MSH3_HUMAN
NC score	0.828198 (rank : 3)	θ value	4.86918e-46 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

MSH3_MOUSE
NC score	0.822937 (rank : 4)	θ value	6.15952e-41 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P13705	Gene names	Msh3, Rep-3
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Repair-3 protein) (REP-1).

MSH2_MOUSE
NC score	0.805653 (rank : 5)	θ value	3.16345e-37 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P43247	Gene names	Msh2
Domain Architecture
Description	DNA mismatch repair protein Msh2 (MutS protein homolog 2).

MSH4_HUMAN
NC score	0.800886 (rank : 6)	θ value	5.584e-34 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	O15457, Q8NEB3, Q9UNP8	Gene names	MSH4
Domain Architecture
Description	MutS protein homolog 4.

MSH2_HUMAN
NC score	0.799587 (rank : 7)	θ value	1.46948e-34 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P43246, O75488	Gene names	MSH2
Domain Architecture
Description	DNA mismatch repair protein Msh2 (MutS protein homolog 2).

MSH4_MOUSE
NC score	0.798839 (rank : 8)	θ value	1.12514e-34 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

MSH6_MOUSE
NC score	0.763835 (rank : 9)	θ value	1.24399e-33 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_HUMAN
NC score	0.754730 (rank : 10)	θ value	1.16434e-31 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

ZCPW1_HUMAN
NC score	0.054223 (rank : 11)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

CBS_HUMAN
NC score	0.036123 (rank : 12)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

NASP_HUMAN
NC score	0.031034 (rank : 13)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MEP1B_MOUSE
NC score	0.021867 (rank : 14)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1B_HUMAN
NC score	0.015469 (rank : 15)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

HCN2_HUMAN
NC score	0.012497 (rank : 16)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CP250_HUMAN
NC score	0.009162 (rank : 17)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	1805	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CSAD_MOUSE
NC score	0.006722 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBE0	Gene names	Csad
Domain Architecture
Description	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Sulfinoalanine decarboxylase) (Cysteine-sulfinate decarboxylase).

ABCB9_MOUSE
NC score	0.006003 (rank : 19)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

MMP15_MOUSE
NC score	0.004834 (rank : 20)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

INVS_MOUSE
NC score	0.004382 (rank : 21)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	609	Shared Neighborhood Hits	4
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

INVS_HUMAN
NC score	0.004095 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

HXA4_MOUSE
NC score	0.002008 (rank : 23)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).