Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CBS_HUMAN

For an explanation of this page, click here

CBS_HUMAN
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

SRR_HUMAN
θ value	2.98157e-11 (rank : 2)	NC score	0.471098 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZT4	Gene names	SRR
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

SRR_MOUSE
θ value	6.64225e-11 (rank : 3)	NC score	0.478050 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZX7	Gene names	Srr
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

PER3_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.048698 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	479	Shared Neighborhood Hits	4
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CLCN6_MOUSE
θ value	0.47712 (rank : 5)	NC score	0.060377 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

SDHL_MOUSE
θ value	0.813845 (rank : 6)	NC score	0.181362 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

CLCN6_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.055973 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

TITIN_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.009499 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GSCR1_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.036294 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

EMID2_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.020550 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

PTN12_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.013153 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

STAC3_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.023212 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

MSH5_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.036123 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

TCOF_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.028955 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MSH5_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.034486 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUM7, Q9Z1Q6	Gene names	Msh5
Domain Architecture	No domain graphic available
Description	MutS protein homolog 5.

ZN696_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.001172 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	743	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7X3	Gene names	ZNF696
Domain Architecture	No domain graphic available
Description	Zinc finger protein 696.

BHLH3_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.021491 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

CO5A1_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.009206 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	434	Shared Neighborhood Hits	4
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

NKTR_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.011046 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	658	Shared Neighborhood Hits	4
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RIN2_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.018075 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

LAG3_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.022514 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

SDHL_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.135779 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P20132	Gene names	SDS, SDH
Domain Architecture
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

Hits sorted by NC score

CBS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35520, Q99425, Q9BWC5	Gene names	CBS
Domain Architecture
Description	Cystathionine beta-synthase (EC 4.2.1.22) (Serine sulfhydrase) (Beta- thionase).

SRR_MOUSE
NC score	0.478050 (rank : 2)	θ value	6.64225e-11 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZX7	Gene names	Srr
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

SRR_HUMAN
NC score	0.471098 (rank : 3)	θ value	2.98157e-11 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZT4	Gene names	SRR
Domain Architecture
Description	Serine racemase (EC 5.1.1.-).

SDHL_MOUSE
NC score	0.181362 (rank : 4)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

SDHL_HUMAN
NC score	0.135779 (rank : 5)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P20132	Gene names	SDS, SDH
Domain Architecture
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

CLCN6_MOUSE
NC score	0.060377 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

CLCN6_HUMAN
NC score	0.055973 (rank : 7)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

PER3_HUMAN
NC score	0.048698 (rank : 8)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	479	Shared Neighborhood Hits	4
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

GSCR1_HUMAN
NC score	0.036294 (rank : 9)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MSH5_HUMAN
NC score	0.036123 (rank : 10)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

MSH5_MOUSE
NC score	0.034486 (rank : 11)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUM7, Q9Z1Q6	Gene names	Msh5
Domain Architecture	No domain graphic available
Description	MutS protein homolog 5.

TCOF_HUMAN
NC score	0.028955 (rank : 12)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

STAC3_MOUSE
NC score	0.023212 (rank : 13)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

LAG3_HUMAN
NC score	0.022514 (rank : 14)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

BHLH3_HUMAN
NC score	0.021491 (rank : 15)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

EMID2_HUMAN
NC score	0.020550 (rank : 16)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

RIN2_HUMAN
NC score	0.018075 (rank : 17)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

PTN12_MOUSE
NC score	0.013153 (rank : 18)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

NKTR_HUMAN
NC score	0.011046 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	658	Shared Neighborhood Hits	4
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TITIN_HUMAN
NC score	0.009499 (rank : 20)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CO5A1_HUMAN
NC score	0.009206 (rank : 21)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	434	Shared Neighborhood Hits	4
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

ZN696_HUMAN
NC score	0.001172 (rank : 22)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	743	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7X3	Gene names	ZNF696
Domain Architecture	No domain graphic available
Description	Zinc finger protein 696.