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Network neighborhood for query Sequence : SENP7_HUMAN

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SENP7_HUMAN
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SENP7_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP6_HUMAN
θ value	1.08223e-53 (rank : 2)	NC score	0.771824 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP1_MOUSE
θ value	2.28291e-11 (rank : 3)	NC score	0.518660 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_HUMAN
θ value	5.08577e-11 (rank : 4)	NC score	0.520830 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_HUMAN
θ value	7.34386e-10 (rank : 5)	NC score	0.509018 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_MOUSE
θ value	7.34386e-10 (rank : 6)	NC score	0.513076 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP5_HUMAN
θ value	1.80886e-08 (rank : 7)	NC score	0.473921 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP3_HUMAN
θ value	3.77169e-06 (rank : 8)	NC score	0.448861 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
θ value	3.77169e-06 (rank : 9)	NC score	0.446848 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

RIF1_HUMAN
θ value	5.44631e-05 (rank : 10)	NC score	0.141188 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	320	Shared Neighborhood Hits	26
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

FLIP1_MOUSE
θ value	0.00665767 (rank : 11)	NC score	0.050728 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	1176	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CYLC1_HUMAN
θ value	0.0252991 (rank : 12)	NC score	0.098154 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DSPP_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.102355 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ATRX_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.083504 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	842	Shared Neighborhood Hits	51
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DSPP_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.092039 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MYRIP_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.067147 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

REST_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.043190 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	1605	Shared Neighborhood Hits	42
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

THOC2_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.089196 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

GPTC8_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.070788 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

YTDC1_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.086963 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CLSPN_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.070063 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

ZN318_HUMAN
θ value	0.279714 (rank : 22)	NC score	0.058121 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

AP3B2_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.046865 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

PRP40_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.075440 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	442	Shared Neighborhood Hits	32
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

WDR60_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.058467 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ATRX_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.078430 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

RRP5_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.062657 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

CHD1_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.031216 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	20
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

TITIN_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.014739 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	2923	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

K0423_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.041866 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

REST_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.037546 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	1506	Shared Neighborhood Hits	40
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ROCK1_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.017060 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	2000	Shared Neighborhood Hits	35
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CI039_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.040044 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	1171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

PPIG_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.048537 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	670	Shared Neighborhood Hits	47
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPGR_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.043952 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

SDC3_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.040756 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

DMP1_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.069331 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

GCC2_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.031445 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	1619	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MAP9_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.061751 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	518	Shared Neighborhood Hits	37
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PRP40_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.064821 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	447	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

ZHX1_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.023229 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

CD2L1_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.010143 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	1463	Shared Neighborhood Hits	40
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CIR_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.050134 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

ESCO1_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.031674 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

NCA11_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.015838 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA12_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.015922 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	437	Shared Neighborhood Hits	5
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NKTR_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.050129 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	658	Shared Neighborhood Hits	41
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

YSK4_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.006400 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	921	Shared Neighborhood Hits	14
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

ZC11A_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.039564 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC313_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.047621 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	772	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CENPF_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.030487 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	1932	Shared Neighborhood Hits	48
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DMP1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.079161 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ELOA1_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.046824 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MINT_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.033735 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	1291	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SENP8_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.098527 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

SVIL_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.023856 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

VSX1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.009681 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

DCR1A_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.024236 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

KLF6_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.000748 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	693	Shared Neighborhood Hits	2
SwissProt Accessions	Q99612, Q5VUT7, Q5VUT8, Q9BT79	Gene names	KLF6, BCD1, COPEB, CPBP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 6 (Core promoter element-binding protein) (B- cell-derived protein 1) (Proto-oncogene BCD1) (Transcription factor Zf9) (GC-rich sites-binding factor GBF).

MYO5C_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.019152 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	1206	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ROCK1_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.016553 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	2126	Shared Neighborhood Hits	40
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

UPAR_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.034455 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P35456	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, GPI-anchored form precursor (uPAR) (U-PAR) (CD87 antigen).

UPAS_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.041044 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P35457	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, secreted form precursor (uPAR) (U-PAR) (CD87 antigen).

ZAN_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.010639 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	808	Shared Neighborhood Hits	6
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CEP57_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.033728 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	580	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

FREM2_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.011331 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

GCC2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.028563 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	1558	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

HM20A_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.030320 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.030146 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	348	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

MCM3_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.012760 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

PHF14_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.027510 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

POT15_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.014426 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	893	Shared Neighborhood Hits	29
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RBP24_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.028542 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SPAT7_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.026716 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VP2, Q8BK23	Gene names	Spata7
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 homolog.

GOGA4_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.026640 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	2034	Shared Neighborhood Hits	45
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K1383_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.041956 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

MAML3_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.015811 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MSH4_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.013597 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

RBBP6_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.047308 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

AHTF1_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.014451 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CB010_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.036798 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

CJ068_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.023891 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CLMN_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.007308 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

EST1A_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.016240 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

HOME1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.021535 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	564	Shared Neighborhood Hits	16
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

IL6RB_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.011446 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

NEK1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.007362 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

PRP4B_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.008950 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	1040	Shared Neighborhood Hits	26
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

PTN13_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.003734 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RARG1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.008874 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.008898 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.008820 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.008837 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RSRC1_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.024743 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SLK_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.009933 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	1798	Shared Neighborhood Hits	41
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TPR_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.028576 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	1921	Shared Neighborhood Hits	45
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UBP26_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.011577 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

IWS1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.050598 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	1241	Shared Neighborhood Hits	45
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.050468 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RBBP6_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.056760 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RIF1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.081567 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SENP8_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.099131 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

Hits sorted by NC score

SENP7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP6_HUMAN
NC score	0.771824 (rank : 2)	θ value	1.08223e-53 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP1_HUMAN
NC score	0.520830 (rank : 3)	θ value	5.08577e-11 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
NC score	0.518660 (rank : 4)	θ value	2.28291e-11 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_MOUSE
NC score	0.513076 (rank : 5)	θ value	7.34386e-10 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_HUMAN
NC score	0.509018 (rank : 6)	θ value	7.34386e-10 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP5_HUMAN
NC score	0.473921 (rank : 7)	θ value	1.80886e-08 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP3_HUMAN
NC score	0.448861 (rank : 8)	θ value	3.77169e-06 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
NC score	0.446848 (rank : 9)	θ value	3.77169e-06 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

RIF1_HUMAN
NC score	0.141188 (rank : 10)	θ value	5.44631e-05 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	320	Shared Neighborhood Hits	26
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

DSPP_MOUSE
NC score	0.102355 (rank : 11)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SENP8_HUMAN
NC score	0.099131 (rank : 12)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
NC score	0.098527 (rank : 13)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

CYLC1_HUMAN
NC score	0.098154 (rank : 14)	θ value	0.0252991 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DSPP_HUMAN
NC score	0.092039 (rank : 15)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

THOC2_HUMAN
NC score	0.089196 (rank : 16)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

YTDC1_HUMAN
NC score	0.086963 (rank : 17)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	458	Shared Neighborhood Hits	36
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ATRX_HUMAN
NC score	0.083504 (rank : 18)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	842	Shared Neighborhood Hits	51
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RIF1_MOUSE
NC score	0.081567 (rank : 19)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

DMP1_HUMAN
NC score	0.079161 (rank : 20)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ATRX_MOUSE
NC score	0.078430 (rank : 21)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

PRP40_HUMAN
NC score	0.075440 (rank : 22)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	442	Shared Neighborhood Hits	32
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

GPTC8_HUMAN
NC score	0.070788 (rank : 23)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CLSPN_HUMAN
NC score	0.070063 (rank : 24)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DMP1_MOUSE
NC score	0.069331 (rank : 25)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MYRIP_HUMAN
NC score	0.067147 (rank : 26)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PRP40_MOUSE
NC score	0.064821 (rank : 27)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	447	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RRP5_HUMAN
NC score	0.062657 (rank : 28)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

MAP9_HUMAN
NC score	0.061751 (rank : 29)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	518	Shared Neighborhood Hits	37
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

WDR60_HUMAN
NC score	0.058467 (rank : 30)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZN318_HUMAN
NC score	0.058121 (rank : 31)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

RBBP6_HUMAN
NC score	0.056760 (rank : 32)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FLIP1_MOUSE
NC score	0.050728 (rank : 33)	θ value	0.00665767 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	1176	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

IWS1_HUMAN
NC score	0.050598 (rank : 34)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	1241	Shared Neighborhood Hits	45
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
NC score	0.050468 (rank : 35)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CIR_MOUSE
NC score	0.050134 (rank : 36)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

NKTR_HUMAN
NC score	0.050129 (rank : 37)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	658	Shared Neighborhood Hits	41
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPIG_HUMAN
NC score	0.048537 (rank : 38)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	670	Shared Neighborhood Hits	47
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

ZC313_HUMAN
NC score	0.047621 (rank : 39)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	772	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RBBP6_MOUSE
NC score	0.047308 (rank : 40)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

AP3B2_MOUSE
NC score	0.046865 (rank : 41)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ELOA1_HUMAN
NC score	0.046824 (rank : 42)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

RPGR_HUMAN
NC score	0.043952 (rank : 43)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

REST_HUMAN
NC score	0.043190 (rank : 44)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	1605	Shared Neighborhood Hits	42
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

K1383_HUMAN
NC score	0.041956 (rank : 45)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

K0423_HUMAN
NC score	0.041866 (rank : 46)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

UPAS_MOUSE
NC score	0.041044 (rank : 47)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P35457	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, secreted form precursor (uPAR) (U-PAR) (CD87 antigen).

SDC3_MOUSE
NC score	0.040756 (rank : 48)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

CI039_HUMAN
NC score	0.040044 (rank : 49)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	1171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ZC11A_MOUSE
NC score	0.039564 (rank : 50)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

REST_MOUSE
NC score	0.037546 (rank : 51)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	1506	Shared Neighborhood Hits	40
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CB010_HUMAN
NC score	0.036798 (rank : 52)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

UPAR_MOUSE
NC score	0.034455 (rank : 53)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P35456	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, GPI-anchored form precursor (uPAR) (U-PAR) (CD87 antigen).

MINT_HUMAN
NC score	0.033735 (rank : 54)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	1291	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CEP57_MOUSE
NC score	0.033728 (rank : 55)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	580	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

ESCO1_MOUSE
NC score	0.031674 (rank : 56)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

GCC2_MOUSE
NC score	0.031445 (rank : 57)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	1619	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CHD1_HUMAN
NC score	0.031216 (rank : 58)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	20
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CENPF_HUMAN
NC score	0.030487 (rank : 59)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	1932	Shared Neighborhood Hits	48
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HM20A_HUMAN
NC score	0.030320 (rank : 60)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.030146 (rank : 61)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	348	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

TPR_HUMAN
NC score	0.028576 (rank : 62)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	1921	Shared Neighborhood Hits	45
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GCC2_HUMAN
NC score	0.028563 (rank : 63)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	1558	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.028542 (rank : 64)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

PHF14_HUMAN
NC score	0.027510 (rank : 65)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

SPAT7_MOUSE
NC score	0.026716 (rank : 66)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VP2, Q8BK23	Gene names	Spata7
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 homolog.

GOGA4_HUMAN
NC score	0.026640 (rank : 67)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	2034	Shared Neighborhood Hits	45
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RSRC1_MOUSE
NC score	0.024743 (rank : 68)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

DCR1A_MOUSE
NC score	0.024236 (rank : 69)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

CJ068_HUMAN
NC score	0.023891 (rank : 70)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

SVIL_HUMAN
NC score	0.023856 (rank : 71)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

ZHX1_HUMAN
NC score	0.023229 (rank : 72)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

HOME1_HUMAN
NC score	0.021535 (rank : 73)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	564	Shared Neighborhood Hits	16
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

MYO5C_HUMAN
NC score	0.019152 (rank : 74)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	1206	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ROCK1_HUMAN
NC score	0.017060 (rank : 75)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	2000	Shared Neighborhood Hits	35
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
NC score	0.016553 (rank : 76)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	2126	Shared Neighborhood Hits	40
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

EST1A_MOUSE
NC score	0.016240 (rank : 77)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	138	Shared Neighborhood Hits	8
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

NCA12_HUMAN
NC score	0.015922 (rank : 78)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	437	Shared Neighborhood Hits	5
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA11_HUMAN
NC score	0.015838 (rank : 79)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

MAML3_HUMAN
NC score	0.015811 (rank : 80)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	323	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

TITIN_HUMAN
NC score	0.014739 (rank : 81)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	2923	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AHTF1_MOUSE
NC score	0.014451 (rank : 82)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

POT15_HUMAN
NC score	0.014426 (rank : 83)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	893	Shared Neighborhood Hits	29
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

MSH4_MOUSE
NC score	0.013597 (rank : 84)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

MCM3_HUMAN
NC score	0.012760 (rank : 85)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

UBP26_MOUSE
NC score	0.011577 (rank : 86)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

IL6RB_MOUSE
NC score	0.011446 (rank : 87)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

FREM2_MOUSE
NC score	0.011331 (rank : 88)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

ZAN_MOUSE
NC score	0.010639 (rank : 89)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	808	Shared Neighborhood Hits	6
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CD2L1_MOUSE
NC score	0.010143 (rank : 90)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	1463	Shared Neighborhood Hits	40
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

SLK_MOUSE
NC score	0.009933 (rank : 91)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	1798	Shared Neighborhood Hits	41
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

VSX1_MOUSE
NC score	0.009681 (rank : 92)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

PRP4B_MOUSE
NC score	0.008950 (rank : 93)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	1040	Shared Neighborhood Hits	26
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

RARG1_MOUSE
NC score	0.008898 (rank : 94)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG1_HUMAN
NC score	0.008874 (rank : 95)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.008837 (rank : 96)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG2_HUMAN
NC score	0.008820 (rank : 97)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

NEK1_MOUSE
NC score	0.007362 (rank : 98)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

CLMN_MOUSE
NC score	0.007308 (rank : 99)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

YSK4_HUMAN
NC score	0.006400 (rank : 100)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	921	Shared Neighborhood Hits	14
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

PTN13_MOUSE
NC score	0.003734 (rank : 101)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

KLF6_HUMAN
NC score	0.000748 (rank : 102)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	693	Shared Neighborhood Hits	2
SwissProt Accessions	Q99612, Q5VUT7, Q5VUT8, Q9BT79	Gene names	KLF6, BCD1, COPEB, CPBP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 6 (Core promoter element-binding protein) (B- cell-derived protein 1) (Proto-oncogene BCD1) (Transcription factor Zf9) (GC-rich sites-binding factor GBF).