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Network neighborhood for query Sequence : SENP8_HUMAN

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SENP8_HUMAN
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SENP8_HUMAN
θ value	5.44333e-122 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
θ value	3.53647e-113 (rank : 2)	NC score	0.997392 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

SENP5_HUMAN
θ value	0.000270298 (rank : 3)	NC score	0.296252 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP3_MOUSE
θ value	0.000602161 (rank : 4)	NC score	0.280659 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP3_HUMAN
θ value	0.00134147 (rank : 5)	NC score	0.275433 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP1_HUMAN
θ value	0.0431538 (rank : 6)	NC score	0.222132 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.213071 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP6_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.152415 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP2_HUMAN
θ value	θ > 10 (rank : 9)	NC score	0.136565 (rank : 10)
Query Neighborhood Hits	8	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_MOUSE
θ value	θ > 10 (rank : 10)	NC score	0.137138 (rank : 9)
Query Neighborhood Hits	8	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP7_HUMAN
θ value	θ > 10 (rank : 11)	NC score	0.099131 (rank : 11)
Query Neighborhood Hits	8	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

Hits sorted by NC score

SENP8_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.44333e-122 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
NC score	0.997392 (rank : 2)	θ value	3.53647e-113 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

SENP5_HUMAN
NC score	0.296252 (rank : 3)	θ value	0.000270298 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP3_MOUSE
NC score	0.280659 (rank : 4)	θ value	0.000602161 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP3_HUMAN
NC score	0.275433 (rank : 5)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP1_HUMAN
NC score	0.222132 (rank : 6)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
NC score	0.213071 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP6_HUMAN
NC score	0.152415 (rank : 8)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP2_MOUSE
NC score	0.137138 (rank : 9)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	8	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_HUMAN
NC score	0.136565 (rank : 10)	θ value	θ > 10 (rank : 9)
Query Neighborhood Hits	8	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP7_HUMAN
NC score	0.099131 (rank : 11)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	8	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).