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Network neighborhood for query Sequence : SENP2_HUMAN

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SENP2_HUMAN
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SENP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_MOUSE
θ value	0 (rank : 2)	NC score	0.998202 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP1_MOUSE
θ value	2.31364e-80 (rank : 3)	NC score	0.923250 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_HUMAN
θ value	1.26953e-78 (rank : 4)	NC score	0.926097 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP3_HUMAN
θ value	2.26708e-35 (rank : 5)	NC score	0.817099 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
θ value	5.0505e-35 (rank : 6)	NC score	0.813431 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP5_HUMAN
θ value	5.584e-34 (rank : 7)	NC score	0.812454 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP6_HUMAN
θ value	1.33837e-11 (rank : 8)	NC score	0.547410 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
θ value	7.34386e-10 (rank : 9)	NC score	0.509018 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	97	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

K0690_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.056753 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

APOF_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.029406 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q13790, Q8TC13	Gene names	APOF
Domain Architecture	No domain graphic available
Description	Apolipoprotein F precursor (Apo-F) (Lipid transfer inhibitor protein) (LTIP).

CE152_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.003595 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	976	Shared Neighborhood Hits	4
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TITIN_HUMAN
θ value	6.88961 (rank : 13)	NC score	-0.000333 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WAPL_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.012139 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

K0690_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.035339 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

SPTA2_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.004936 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	888	Shared Neighborhood Hits	4
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

STAG3_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.006758 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

TCPE_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.008031 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.008038 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

SENP8_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.136565 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
θ value	θ > 10 (rank : 21)	NC score	0.110110 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

Hits sorted by NC score

SENP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_MOUSE
NC score	0.998202 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP1_HUMAN
NC score	0.926097 (rank : 3)	θ value	1.26953e-78 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
NC score	0.923250 (rank : 4)	θ value	2.31364e-80 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP3_HUMAN
NC score	0.817099 (rank : 5)	θ value	2.26708e-35 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
NC score	0.813431 (rank : 6)	θ value	5.0505e-35 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP5_HUMAN
NC score	0.812454 (rank : 7)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP6_HUMAN
NC score	0.547410 (rank : 8)	θ value	1.33837e-11 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
NC score	0.509018 (rank : 9)	θ value	7.34386e-10 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	97	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP8_HUMAN
NC score	0.136565 (rank : 10)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
NC score	0.110110 (rank : 11)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

K0690_MOUSE
NC score	0.056753 (rank : 12)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

K0690_HUMAN
NC score	0.035339 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

APOF_HUMAN
NC score	0.029406 (rank : 14)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q13790, Q8TC13	Gene names	APOF
Domain Architecture	No domain graphic available
Description	Apolipoprotein F precursor (Apo-F) (Lipid transfer inhibitor protein) (LTIP).

WAPL_MOUSE
NC score	0.012139 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

TCPE_MOUSE
NC score	0.008038 (rank : 16)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
NC score	0.008031 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

STAG3_HUMAN
NC score	0.006758 (rank : 18)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

SPTA2_HUMAN
NC score	0.004936 (rank : 19)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	888	Shared Neighborhood Hits	4
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

CE152_HUMAN
NC score	0.003595 (rank : 20)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	976	Shared Neighborhood Hits	4
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TITIN_HUMAN
NC score	-0.000333 (rank : 21)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	2923	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).