Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : WBP4_HUMAN

For an explanation of this page, click here

WBP4_HUMAN
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WBP4_HUMAN
θ value	3.47952e-169 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBP4_MOUSE
θ value	2.52267e-127 (rank : 2)	NC score	0.942255 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	100	Shared Neighborhood Hits	34
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

PRP40_HUMAN
θ value	7.34386e-10 (rank : 3)	NC score	0.405093 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	7.34386e-10 (rank : 4)	NC score	0.406196 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

TCRG1_HUMAN
θ value	0.00228821 (rank : 5)	NC score	0.184246 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	929	Shared Neighborhood Hits	43
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	0.00228821 (rank : 6)	NC score	0.181522 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	947	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

IQGA1_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.156523 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

RU1C_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.230562 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	0.0148317 (rank : 9)	NC score	0.228862 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

IQGA1_MOUSE
θ value	0.0252991 (rank : 10)	NC score	0.151935 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

GAS7_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.147562 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	259	Shared Neighborhood Hits	24
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

YTDC1_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.095236 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	458	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

K1688_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.098450 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

NKTR_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.064874 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

GAS7_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.138185 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GP179_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.056607 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

IQGA2_HUMAN
θ value	0.21417 (rank : 17)	NC score	0.144408 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

OXR1_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.072979 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	516	Shared Neighborhood Hits	22
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SEC63_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.088375 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	601	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

HSP7C_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.030029 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

IQGA3_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.150241 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

RPTN_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.045930 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SEC63_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.082591 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	586	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

MYRIP_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.058460 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PSIP1_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.062825 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

TCF8_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.011618 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	1067	Shared Neighborhood Hits	17
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

IWS1_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.077766 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	1258	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RHG12_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.078215 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SIA7A_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.029984 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

CEP63_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.021259 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	1005	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

HORN_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.042910 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

NFM_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.029209 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	1328	Shared Neighborhood Hits	46
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SDPR_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.035212 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

ITCH_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.054943 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	162	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.055423 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

IWS1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.082115 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	1241	Shared Neighborhood Hits	37
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYRIP_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.049152 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PHF10_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.021491 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

RHG18_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.035709 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

IRX3_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.023783 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

MINT_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.026773 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	1514	Shared Neighborhood Hits	35
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NPBL_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.055927 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PIN1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.100121 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.114665 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

RHG12_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.068825 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ANR11_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.031096 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	1289	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BARH2_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.010028 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

DGC14_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.055874 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

DMP1_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.058531 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

HSP7C_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.024882 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

IRX3_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.022104 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

LRCH2_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.010336 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MYT1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.038372 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	475	Shared Neighborhood Hits	30
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NED4L_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.046219 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	238	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NIPBL_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.055026 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	1311	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

OGFR_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.029402 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	584	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PDE10_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.012562 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

SETD2_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.087522 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ADA17_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.011223 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

GANAB_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.014199 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GAS8_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.014550 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	819	Shared Neighborhood Hits	16
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

LEO1_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.059542 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LRRF1_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.032370 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	625	Shared Neighborhood Hits	24
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LSP1_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.036889 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

MOR2A_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.014809 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

NCKX1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.036634 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

PCIF1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.035309 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

TCF8_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.012750 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	1057	Shared Neighborhood Hits	27
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

WWP1_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.058735 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

DYNA_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.021827 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	1194	Shared Neighborhood Hits	25
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.022919 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	1084	Shared Neighborhood Hits	26
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

LEO1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.063982 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NEDD4_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.046356 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NRX1A_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.007889 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PQBP1_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.049540 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

RAD50_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.014449 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	1366	Shared Neighborhood Hits	28
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SUHW4_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.005693 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	737	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

YO11_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.026342 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

AMD_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.014423 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

EVPL_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.012909 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

KIF5C_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.010943 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	974	Shared Neighborhood Hits	21
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.011002 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	1040	Shared Neighborhood Hits	22
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LRC50_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.012402 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	275	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MYT1_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.031298 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	385	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ROCK2_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.003429 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	2073	Shared Neighborhood Hits	23
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

WDFY3_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.007264 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

CCD55_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.054432 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CYLC2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.062315 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.054773 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

K1688_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.057153 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

NUCKS_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050873 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.059107 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PINL_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.080085 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PKCB1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.052536 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	488	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

WWP1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.052899 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	262	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP2_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.053656 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.053483 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

YAP1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.053303 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

Hits sorted by NC score

WBP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.47952e-169 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBP4_MOUSE
NC score	0.942255 (rank : 2)	θ value	2.52267e-127 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	100	Shared Neighborhood Hits	34
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

PRP40_MOUSE
NC score	0.406196 (rank : 3)	θ value	7.34386e-10 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.405093 (rank : 4)	θ value	7.34386e-10 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RU1C_HUMAN
NC score	0.230562 (rank : 5)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
NC score	0.228862 (rank : 6)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

TCRG1_HUMAN
NC score	0.184246 (rank : 7)	θ value	0.00228821 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	929	Shared Neighborhood Hits	43
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.181522 (rank : 8)	θ value	0.00228821 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	947	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

IQGA1_HUMAN
NC score	0.156523 (rank : 9)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
NC score	0.151935 (rank : 10)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

IQGA3_HUMAN
NC score	0.150241 (rank : 11)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

GAS7_MOUSE
NC score	0.147562 (rank : 12)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	259	Shared Neighborhood Hits	24
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

IQGA2_HUMAN
NC score	0.144408 (rank : 13)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

GAS7_HUMAN
NC score	0.138185 (rank : 14)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PIN1_MOUSE
NC score	0.114665 (rank : 15)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_HUMAN
NC score	0.100121 (rank : 16)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

K1688_HUMAN
NC score	0.098450 (rank : 17)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

YTDC1_HUMAN
NC score	0.095236 (rank : 18)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	458	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

SEC63_MOUSE
NC score	0.088375 (rank : 19)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	601	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SETD2_HUMAN
NC score	0.087522 (rank : 20)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SEC63_HUMAN
NC score	0.082591 (rank : 21)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	586	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

IWS1_HUMAN
NC score	0.082115 (rank : 22)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	1241	Shared Neighborhood Hits	37
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PINL_HUMAN
NC score	0.080085 (rank : 23)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RHG12_MOUSE
NC score	0.078215 (rank : 24)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

IWS1_MOUSE
NC score	0.077766 (rank : 25)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	1258	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

OXR1_MOUSE
NC score	0.072979 (rank : 26)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	516	Shared Neighborhood Hits	22
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

RHG12_HUMAN
NC score	0.068825 (rank : 27)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

NKTR_HUMAN
NC score	0.064874 (rank : 28)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

LEO1_HUMAN
NC score	0.063982 (rank : 29)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PSIP1_MOUSE
NC score	0.062825 (rank : 30)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

CYLC2_HUMAN
NC score	0.062315 (rank : 31)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

LEO1_MOUSE
NC score	0.059542 (rank : 32)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NUCKS_MOUSE
NC score	0.059107 (rank : 33)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

WWP1_MOUSE
NC score	0.058735 (rank : 34)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

DMP1_MOUSE
NC score	0.058531 (rank : 35)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MYRIP_HUMAN
NC score	0.058460 (rank : 36)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

K1688_MOUSE
NC score	0.057153 (rank : 37)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

GP179_HUMAN
NC score	0.056607 (rank : 38)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

NPBL_MOUSE
NC score	0.055927 (rank : 39)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

DGC14_MOUSE
NC score	0.055874 (rank : 40)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

ITCH_MOUSE
NC score	0.055423 (rank : 41)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NIPBL_HUMAN
NC score	0.055026 (rank : 42)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	1311	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ITCH_HUMAN
NC score	0.054943 (rank : 43)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	162	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

DMP1_HUMAN
NC score	0.054773 (rank : 44)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CCD55_MOUSE
NC score	0.054432 (rank : 45)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	519	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

WWP2_HUMAN
NC score	0.053656 (rank : 46)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
NC score	0.053483 (rank : 47)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

YAP1_MOUSE
NC score	0.053303 (rank : 48)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWP1_HUMAN
NC score	0.052899 (rank : 49)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	262	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

PKCB1_HUMAN
NC score	0.052536 (rank : 50)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	488	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

NUCKS_HUMAN
NC score	0.050873 (rank : 51)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PQBP1_MOUSE
NC score	0.049540 (rank : 52)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

MYRIP_MOUSE
NC score	0.049152 (rank : 53)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NEDD4_MOUSE
NC score	0.046356 (rank : 54)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NED4L_HUMAN
NC score	0.046219 (rank : 55)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	238	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

RPTN_MOUSE
NC score	0.045930 (rank : 56)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

HORN_MOUSE
NC score	0.042910 (rank : 57)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

MYT1_HUMAN
NC score	0.038372 (rank : 58)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	475	Shared Neighborhood Hits	30
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

LSP1_HUMAN
NC score	0.036889 (rank : 59)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

NCKX1_HUMAN
NC score	0.036634 (rank : 60)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

RHG18_MOUSE
NC score	0.035709 (rank : 61)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

PCIF1_HUMAN
NC score	0.035309 (rank : 62)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

SDPR_HUMAN
NC score	0.035212 (rank : 63)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

LRRF1_HUMAN
NC score	0.032370 (rank : 64)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	625	Shared Neighborhood Hits	24
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MYT1_MOUSE
NC score	0.031298 (rank : 65)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	385	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ANR11_HUMAN
NC score	0.031096 (rank : 66)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	1289	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

HSP7C_MOUSE
NC score	0.030029 (rank : 67)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

SIA7A_HUMAN
NC score	0.029984 (rank : 68)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	177	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

OGFR_MOUSE
NC score	0.029402 (rank : 69)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	584	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

NFM_HUMAN
NC score	0.029209 (rank : 70)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	1328	Shared Neighborhood Hits	46
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MINT_MOUSE
NC score	0.026773 (rank : 71)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	1514	Shared Neighborhood Hits	35
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

YO11_MOUSE
NC score	0.026342 (rank : 72)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

HSP7C_HUMAN
NC score	0.024882 (rank : 73)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

IRX3_HUMAN
NC score	0.023783 (rank : 74)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

DYNA_MOUSE
NC score	0.022919 (rank : 75)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	1084	Shared Neighborhood Hits	26
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

IRX3_MOUSE
NC score	0.022104 (rank : 76)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

DYNA_HUMAN
NC score	0.021827 (rank : 77)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	1194	Shared Neighborhood Hits	25
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

PHF10_MOUSE
NC score	0.021491 (rank : 78)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

CEP63_HUMAN
NC score	0.021259 (rank : 79)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	1005	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

MOR2A_MOUSE
NC score	0.014809 (rank : 80)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

GAS8_HUMAN
NC score	0.014550 (rank : 81)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	819	Shared Neighborhood Hits	16
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RAD50_MOUSE
NC score	0.014449 (rank : 82)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	1366	Shared Neighborhood Hits	28
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

AMD_MOUSE
NC score	0.014423 (rank : 83)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

GANAB_MOUSE
NC score	0.014199 (rank : 84)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

EVPL_HUMAN
NC score	0.012909 (rank : 85)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

TCF8_HUMAN
NC score	0.012750 (rank : 86)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	1057	Shared Neighborhood Hits	27
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

PDE10_HUMAN
NC score	0.012562 (rank : 87)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

LRC50_HUMAN
NC score	0.012402 (rank : 88)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	275	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

TCF8_MOUSE
NC score	0.011618 (rank : 89)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	1067	Shared Neighborhood Hits	17
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

ADA17_HUMAN
NC score	0.011223 (rank : 90)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

KIF5C_MOUSE
NC score	0.011002 (rank : 91)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	1040	Shared Neighborhood Hits	22
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_HUMAN
NC score	0.010943 (rank : 92)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	974	Shared Neighborhood Hits	21
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LRCH2_HUMAN
NC score	0.010336 (rank : 93)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

BARH2_HUMAN
NC score	0.010028 (rank : 94)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

NRX1A_HUMAN
NC score	0.007889 (rank : 95)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

WDFY3_MOUSE
NC score	0.007264 (rank : 96)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

SUHW4_MOUSE
NC score	0.005693 (rank : 97)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	737	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ROCK2_HUMAN
NC score	0.003429 (rank : 98)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	2073	Shared Neighborhood Hits	23
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).