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Network neighborhood for query Sequence : PRKRA_MOUSE

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PRKRA_MOUSE
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRKRA_MOUSE
θ value	3.58407e-182 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
θ value	9.76035e-180 (rank : 2)	NC score	0.999708 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	25
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

TRBP2_HUMAN
θ value	1.07722e-69 (rank : 3)	NC score	0.939561 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

TRBP2_MOUSE
θ value	3.13423e-69 (rank : 4)	NC score	0.935188 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

STAU2_MOUSE
θ value	2.60593e-15 (rank : 5)	NC score	0.594449 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_HUMAN
θ value	7.58209e-15 (rank : 6)	NC score	0.595981 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU1_HUMAN
θ value	3.18553e-13 (rank : 7)	NC score	0.583810 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
θ value	6.00763e-12 (rank : 8)	NC score	0.570869 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

DSRAD_HUMAN
θ value	9.92553e-07 (rank : 9)	NC score	0.361560 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

DSRAD_MOUSE
θ value	9.92553e-07 (rank : 10)	NC score	0.335662 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

DGCR8_HUMAN
θ value	0.00134147 (rank : 11)	NC score	0.178647 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	0.00134147 (rank : 12)	NC score	0.178737 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

E2AK2_HUMAN
θ value	0.0330416 (rank : 13)	NC score	0.028792 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

RED1_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.291719 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED2_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.253547 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RED1_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.286701 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED2_MOUSE
θ value	0.0961366 (rank : 17)	NC score	0.233655 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

ILF3_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.227163 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

ILF3_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.219246 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

SON_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.042458 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	1568	Shared Neighborhood Hits	13
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.064677 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	957	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

UROL1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.026123 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

RNC_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.056438 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	176	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

CT032_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.023735 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

RB3GP_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.020410 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UJ7, Q6A0D7, Q8C4Y0, Q8C679, Q8C6A5, Q8K324	Gene names	Rab3gap1, Kiaa0066, Rab3gap
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase- activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP).

Hits sorted by NC score

PRKRA_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.58407e-182 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
NC score	0.999708 (rank : 2)	θ value	9.76035e-180 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	25
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

TRBP2_HUMAN
NC score	0.939561 (rank : 3)	θ value	1.07722e-69 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

TRBP2_MOUSE
NC score	0.935188 (rank : 4)	θ value	3.13423e-69 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

STAU2_HUMAN
NC score	0.595981 (rank : 5)	θ value	7.58209e-15 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_MOUSE
NC score	0.594449 (rank : 6)	θ value	2.60593e-15 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU1_HUMAN
NC score	0.583810 (rank : 7)	θ value	3.18553e-13 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
NC score	0.570869 (rank : 8)	θ value	6.00763e-12 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

DSRAD_HUMAN
NC score	0.361560 (rank : 9)	θ value	9.92553e-07 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

DSRAD_MOUSE
NC score	0.335662 (rank : 10)	θ value	9.92553e-07 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

RED1_HUMAN
NC score	0.291719 (rank : 11)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED1_MOUSE
NC score	0.286701 (rank : 12)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED2_HUMAN
NC score	0.253547 (rank : 13)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RED2_MOUSE
NC score	0.233655 (rank : 14)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

ILF3_HUMAN
NC score	0.227163 (rank : 15)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

ILF3_MOUSE
NC score	0.219246 (rank : 16)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

DGCR8_MOUSE
NC score	0.178737 (rank : 17)	θ value	0.00134147 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

DGCR8_HUMAN
NC score	0.178647 (rank : 18)	θ value	0.00134147 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

SON_MOUSE
NC score	0.064677 (rank : 19)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	957	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

RNC_HUMAN
NC score	0.056438 (rank : 20)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	176	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

SON_HUMAN
NC score	0.042458 (rank : 21)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	1568	Shared Neighborhood Hits	13
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

E2AK2_HUMAN
NC score	0.028792 (rank : 22)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

UROL1_HUMAN
NC score	0.026123 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CT032_HUMAN
NC score	0.023735 (rank : 24)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

RB3GP_MOUSE
NC score	0.020410 (rank : 25)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UJ7, Q6A0D7, Q8C4Y0, Q8C679, Q8C6A5, Q8K324	Gene names	Rab3gap1, Kiaa0066, Rab3gap
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase- activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP).